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    Wyświetlanie 1-15 z 15
    Tytuł:
    Global transcriptional regulation of innate immunity by ATF-7 in C. elegans.
    Autorzy:
    Fletcher M; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Tillman EJ; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Butty VL; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Levine SS; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Kim DH; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
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    Źródło:
    PLoS genetics [PLoS Genet] 2019 Feb 21; Vol. 15 (2), pp. e1007830. Date of Electronic Publication: 2019 Feb 21 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Activating Transcription Factors/*metabolism
    Caenorhabditis elegans/*immunology
    Caenorhabditis elegans/*microbiology
    Caenorhabditis elegans Proteins/*metabolism
    Pseudomonas aeruginosa/*immunology
    Animals ; Caenorhabditis elegans/genetics ; Chromatin Immunoprecipitation ; Gene Expression Profiling/methods ; Gene Expression Regulation ; Genome-Wide Association Study ; Immunity, Innate ; MAP Kinase Signaling System ; Mitogen-Activated Protein Kinases/metabolism ; Sequence Analysis, RNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction.
    Autorzy:
    Herbert ZT; Molecular Biology Core Facilities at Dana-Farber Cancer Institute, Boston, MA, USA.
    Kershner JP; BioFrontiers Institute, Next-Gen Sequencing Facility, University of Colorado Boulder, Boulder, CO, USA.
    Butty VL; MIT BioMicro Center, Massachusetts Institute of Technology, Cambridge, MA, USA.
    Thimmapuram J; Bioinformatics Core, Purdue University, West Lafayette, IN, USA.
    Choudhari S; Bioinformatics Core, Purdue University, West Lafayette, IN, USA.
    Alekseyev YO; Microarray and Sequencing Resource Core Facility, Boston University, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, Boston University, Boston, MA, USA.
    Fan J; Genomic Core Facility, Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA.
    Podnar JW; Genomic Sequencing and Analysis Facility, University of Texas, Austin, TX, USA.
    Wilcox E; DNA Sequencing Center, Brigham Young University, Provo, UT, USA.
    Gipson J; Laboratory for Molecular Biology and Cytometry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
    Gillaspy A; Laboratory for Molecular Biology and Cytometry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
    Jepsen K; IGM Genomics Center, University of California, San Diego, La Jolla, CA, USA.
    BonDurant SS; UW Biotechnology Center, Gene Expression Center, University of Wisconsin-Madison, Madison, WI, USA.
    Morris K; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH, USA.
    Berkeley M; Molecular Biology Core Facilities at Dana-Farber Cancer Institute, Boston, MA, USA.
    LeClerc A; Microarray and Sequencing Resource Core Facility, Boston University, Boston, MA, USA.
    Simpson SD; Hubbard Center for Genome Studies, University of New Hampshire, Durham, NH, USA.
    Sommerville G; Molecular Biology Core Facilities at Dana-Farber Cancer Institute, Boston, MA, USA.
    Grimmett L; Molecular Biology Core Facilities at Dana-Farber Cancer Institute, Boston, MA, USA.
    Adams M; Genomics Core Facility, Van Andel Institute, Grand Rapids, MI, USA.
    Levine SS; MIT BioMicro Center, Massachusetts Institute of Technology, Cambridge, MA, USA. .
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    Źródło:
    BMC genomics [BMC Genomics] 2018 Mar 15; Vol. 19 (1), pp. 199. Date of Electronic Publication: 2018 Mar 15.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    High-Throughput Nucleotide Sequencing/*methods
    RNA, Ribosomal/*isolation & purification
    Sequence Analysis, RNA/*methods
    Gene Expression Profiling/methods ; Gene Library ; Humans ; Poly A/genetics ; RNA, Ribosomal/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Polycomb Repressive Complex 2 regulates lineage fidelity during embryonic stem cell differentiation.
    Autorzy:
    Thornton SR; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Butty VL; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Levine SS; BioMicro Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Boyer LA; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Oct 21; Vol. 9 (10), pp. e110498. Date of Electronic Publication: 2014 Oct 21 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Embryonic Stem Cells/*metabolism
    Polycomb Repressive Complex 2/*metabolism
    Animals ; Cell Differentiation ; Cell Line ; Cell Lineage ; CpG Islands ; DNA Methylation ; Embryonic Stem Cells/cytology ; Gene Expression ; Histones/genetics ; Histones/metabolism ; Mice ; Mice, Inbred C57BL ; Motor Neurons/cytology ; Motor Neurons/metabolism ; Polycomb Repressive Complex 2/genetics ; Promoter Regions, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.
    Autorzy:
    Subramanian V; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
    Mazumder A
    Surface LE
    Butty VL
    Fields PA
    Alwan A
    Torrey L
    Thai KK
    Levine SS
    Bathe M
    Boyer LA
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    Źródło:
    PLoS genetics [PLoS Genet] 2013; Vol. 9 (8), pp. e1003725. Date of Electronic Publication: 2013 Aug 22.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Cell Differentiation/*genetics
    Chromatin/*genetics
    Embryonic Development/*genetics
    Embryonic Stem Cells/*cytology
    Histones/*genetics
    Animals ; Asparagine/genetics ; Cell Lineage/genetics ; Gene Expression Regulation, Developmental ; Glycine/genetics ; Mice ; Nucleosomes/genetics ; Promoter Regions, Genetic ; Serine/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity.
    Autorzy:
    Mellios N; Department of Brain and Cognitive Sciences, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
    Sugihara H
    Castro J
    Banerjee A
    Le C
    Kumar A
    Crawford B
    Strathmann J
    Tropea D
    Levine SS
    Edbauer D
    Sur M
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    Źródło:
    Nature neuroscience [Nat Neurosci] 2011 Sep 04; Vol. 14 (10), pp. 1240-2. Date of Electronic Publication: 2011 Sep 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    MicroRNAs/*physiology
    Neuronal Plasticity/*physiology
    Pyramidal Cells/*physiology
    Visual Cortex/*cytology
    Age Factors ; Analysis of Variance ; Animals ; Animals, Newborn ; Calcium/metabolism ; Critical Period, Psychological ; Darkness ; Dendritic Spines/metabolism ; Dominance, Ocular ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/genetics ; Gene Expression Profiling/methods ; Gene Expression Regulation, Developmental/drug effects ; Gene Expression Regulation, Developmental/physiology ; In Vitro Techniques ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; MicroRNAs/chemistry ; MicroRNAs/genetics ; MicroRNAs/pharmacology ; Molecular Sequence Data ; Nerve Tissue Proteins/metabolism ; Neuronal Plasticity/genetics ; Oligonucleotide Array Sequence Analysis/methods ; Patch-Clamp Techniques ; Photic Stimulation/methods ; Pyramidal Cells/drug effects ; Pyramidal Cells/ultrastructure ; Sensory Deprivation ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Visual Cortex/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mediator and cohesin connect gene expression and chromatin architecture.
    Autorzy:
    Kagey MH; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.
    Newman JJ
    Bilodeau S
    Zhan Y
    Orlando DA
    van Berkum NL
    Ebmeier CC
    Goossens J
    Rahl PB
    Levine SS
    Taatjes DJ
    Dekker J
    Young RA
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    Źródło:
    Nature [Nature] 2010 Sep 23; Vol. 467 (7314), pp. 430-5. Date of Electronic Publication: 2010 Aug 18.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Cycle Proteins/*metabolism
    Chromatin/*genetics
    Chromatin/*metabolism
    Chromatin Assembly and Disassembly/*genetics
    Chromosomal Proteins, Non-Histone/*metabolism
    Embryonic Stem Cells/*metabolism
    Gene Expression Regulation/*genetics
    Mediator Complex/*metabolism
    Animals ; Cell Cycle Proteins/genetics ; Cells, Cultured ; Chromatin/chemistry ; Chromosomal Proteins, Non-Histone/genetics ; DNA/chemistry ; DNA/genetics ; DNA/metabolism ; Embryonic Stem Cells/cytology ; Enhancer Elements, Genetic/genetics ; Fibroblasts ; Mediator Complex/genetics ; Mice ; Nucleic Acid Conformation ; Organ Specificity ; Promoter Regions, Genetic/genetics ; Protein Binding ; Cohesins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Divergent transcription from active promoters.
    Autorzy:
    Seila AC; Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
    Calabrese JM
    Levine SS
    Yeo GW
    Rahl PB
    Flynn RA
    Young RA
    Sharp PA
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    Źródło:
    Science (New York, N.Y.) [Science] 2008 Dec 19; Vol. 322 (5909), pp. 1849-51. Date of Electronic Publication: 2008 Dec 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Promoter Regions, Genetic*
    Transcription, Genetic*
    RNA/*genetics
    RNA, Antisense/*genetics
    Animals ; Embryonic Stem Cells/metabolism ; Gene Expression Regulation ; HeLa Cells ; Histones/metabolism ; Humans ; Methylation ; Mice ; RNA/metabolism ; RNA, Antisense/metabolism ; Transcription Factors/metabolism ; Transcription Initiation Site
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Foxp3 occupancy and regulation of key target genes during T-cell stimulation.
    Autorzy:
    Marson A; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.
    Kretschmer K
    Frampton GM
    Jacobsen ES
    Polansky JK
    MacIsaac KD
    Levine SS
    Fraenkel E
    von Boehmer H
    Young RA
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    Źródło:
    Nature [Nature] 2007 Feb 22; Vol. 445 (7130), pp. 931-5. Date of Electronic Publication: 2007 Jan 21.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Forkhead Transcription Factors/*metabolism
    Gene Expression Regulation/*genetics
    Lymphocyte Activation/*genetics
    T-Lymphocytes, Regulatory/*immunology
    T-Lymphocytes, Regulatory/*metabolism
    Animals ; Cell Line ; Forkhead Transcription Factors/genetics ; Gene Expression Profiling ; Mice ; Models, Immunological ; Phenotype ; T-Lymphocytes, Regulatory/cytology ; Transcription, Genetic/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-15 z 15

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