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Wyszukujesz frazę ""Levis, MJ"" wg kryterium: Autor


Wyświetlanie 1-11 z 11
Tytuł:
Venetoclax in combination with hypomethylating agent for the treatment of advanced myeloproliferative neoplasms and acute myeloid leukemia with extramedullary disease.
Autorzy:
Sanber K; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Ye K; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Tsai HL; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Newman M; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital Department of Pharmacy, Baltimore, MD, USA.
Webster JA; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Gojo I; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Ghiaur G; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Prince GT; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Gondek LP; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Smith BD; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Levis MJ; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
DeZern AE; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Ambinder AJ; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Dalton WB; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Jain T; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2023 Apr; Vol. 64 (4), pp. 846-855. Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloproliferative Disorders*/diagnosis
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Humans ; Retrospective Studies ; Bridged Bicyclo Compounds, Heterocyclic/adverse effects ; Sulfonamides ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Azacitidine/therapeutic use
Czasopismo naukowe
Tytuł:
Genomic landscape of myelodysplastic/myeloproliferative neoplasm can predict response to hypomethylating agent therapy.
Autorzy:
Karantanos T; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Tsai HL; Division of Biostatistics and Bioinformatics, Johns Hopkins/Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
Gondek LP; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
DeZern AE; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Ghiaur G; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Dalton WB; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Gojo I; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Prince GT; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Webster J; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Ambinder A; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Smith BD; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Levis MJ; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Varadhan R; Division of Biostatistics and Bioinformatics, Johns Hopkins/Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
Jones RJ; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
Jain T; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2022 Aug; Vol. 63 (8), pp. 1942-1948. Date of Electronic Publication: 2022 Apr 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Myelodysplastic-Myeloproliferative Diseases*/diagnosis
Myelodysplastic-Myeloproliferative Diseases*/drug therapy
Myelodysplastic-Myeloproliferative Diseases*/genetics
Neoplasms*
Core Binding Factor Alpha 2 Subunit/genetics ; Genomics ; Humans ; Mutation
Czasopismo naukowe
Tytuł:
The impact of FLT3 mutation clearance and treatment response after gilteritinib therapy on overall survival in patients with FLT3 mutation-positive relapsed/refractory acute myeloid leukemia.
Autorzy:
Altman JK; Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA.
Perl AE; Abramson Comprehensive Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Hill JE; Astellas Pharma US, Inc., Northbrook, IL, USA.
Rosales M; Astellas Pharma US, Inc., Northbrook, IL, USA.
Bahceci E; Astellas Pharma US, Inc., Northbrook, IL, USA.
Levis MJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
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Źródło:
Cancer medicine [Cancer Med] 2021 Feb; Vol. 10 (3), pp. 797-805. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Aniline Compounds/*therapeutic use
Drug Resistance, Neoplasm/*genetics
Leukemia, Myeloid, Acute/*mortality
Pyrazines/*therapeutic use
fms-Like Tyrosine Kinase 3/*genetics
Adult ; Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Male ; Middle Aged ; Prognosis ; Protein Kinase Inhibitors/therapeutic use ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł:
Clustered incidence of adult acute promyelocytic leukemia in the vicinity of Baltimore.
Autorzy:
Li AY; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Kashanian SM; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Hambley BC; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Zacholski K; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Baer MR; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.
Duong VH; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.
El Chaer F; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.
Holtzman NG; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.
Norsworthy KJ; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Levis MJ; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Smith BD; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Kamangar F; Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, USA.
Ghiaur G; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Emadi A; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2020 Nov; Vol. 61 (11), pp. 2743-2747. Date of Electronic Publication: 2020 Jun 14.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Leukemia, Promyelocytic, Acute*/diagnosis
Leukemia, Promyelocytic, Acute*/epidemiology
Leukemia, Promyelocytic, Acute*/therapy
Adult ; Baltimore/epidemiology ; Humans ; Incidence ; Tretinoin
Raport
Tytuł:
Clinical implications of molecular markers in acute myeloid leukemia.
Autorzy:
Kayser S; Department of Internal Medicine V, University Hospital of Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Levis MJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland.
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Źródło:
European journal of haematology [Eur J Haematol] 2019 Jan; Vol. 102 (1), pp. 20-35. Date of Electronic Publication: 2018 Oct 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor*
Leukemia, Myeloid, Acute/*genetics
CCAAT-Binding Factor/genetics ; CCAAT-Binding Factor/metabolism ; Genetic Predisposition to Disease ; Genetic Variation ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/mortality ; Leukemia, Myeloid, Acute/therapy ; Leukemia, Promyelocytic, Acute/diagnosis ; Leukemia, Promyelocytic, Acute/genetics ; Leukemia, Promyelocytic, Acute/therapy ; Mutation ; Oncogene Proteins, Fusion ; Translocation, Genetic
Czasopismo naukowe
Tytuł:
Emerging molecular predictive and prognostic factors in acute myeloid leukemia.
Autorzy:
McCurdy SR; a Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Levis MJ; a Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore , MD , USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2018 Sep; Vol. 59 (9), pp. 2021-2039. Date of Electronic Publication: 2017 Nov 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mutation*
Genetic Predisposition to Disease/*genetics
Leukemia, Myeloid/*genetics
Leukemia, Myeloid/*therapy
Acute Disease ; Humans ; Leukemia, Myeloid/pathology ; Neoplasm Recurrence, Local ; Outcome Assessment, Health Care/methods ; Outcome Assessment, Health Care/statistics & numerical data ; Prognosis ; Risk Factors ; Survival Analysis
Czasopismo naukowe
Tytuł:
Expression of putative targets of immunotherapy in acute myeloid leukemia and healthy tissues.
Autorzy:
Goswami M; Myeloid Malignancies Section, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Hensel N; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Smith BD; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Prince GT; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Qin L; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Levitsky HI; 1] Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Cancer Immunology Experimental Medicine, Pharma Research and Early Development, Roche Glycart AG, Schlieren, Switzerland.
Strickland SA; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Jagasia M; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Savani BN; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Fraser JW; Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Sadrzadeh H; Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Rajkhowa T; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ito S; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jain NA; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Battiwalla M; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Fathi AT; Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Levis MJ; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Barrett AJ; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Hourigan CS; Myeloid Malignancies Section, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
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Źródło:
Leukemia [Leukemia] 2014 May; Vol. 28 (5), pp. 1167-70. Date of Electronic Publication: 2014 Jan 10.
Typ publikacji:
Letter; Research Support, N.I.H., Intramural
MeSH Terms:
Immunotherapy*
Leukemia, Myeloid, Acute/*metabolism
Humans
Raport
Tytuł:
FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations.
Autorzy:
Kayser S; Department of Internal Medicine III, University Hospital of Ulm , Germany.
Levis MJ
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2014 Feb; Vol. 55 (2), pp. 243-55. Date of Electronic Publication: 2013 Jun 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Leukemia, Myeloid/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
fms-Like Tyrosine Kinase 3/*antagonists & inhibitors
Acute Disease ; Drug Resistance, Neoplasm/genetics ; Humans ; Leukemia, Myeloid/genetics ; Mutation ; Neoplasm Recurrence, Local ; Tandem Repeat Sequences/genetics ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Tytuł:
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.
Autorzy:
Smith CC; Division of Hematology/Oncology, University of California, San Francisco, California 94143, USA.
Wang Q
Chin CS
Salerno S
Damon LE
Levis MJ
Perl AE
Travers KJ
Wang S
Hunt JP
Zarrinkar PP
Schadt EE
Kasarskis A
Kuriyan J
Shah NP
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Źródło:
Nature [Nature] 2012 Apr 15; Vol. 485 (7397), pp. 260-3. Date of Electronic Publication: 2012 Apr 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Targeted Therapy*
Benzothiazoles/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Leukemia, Myeloid, Acute/*genetics
Mutation/*genetics
Phenylurea Compounds/*therapeutic use
fms-Like Tyrosine Kinase 3/*antagonists & inhibitors
fms-Like Tyrosine Kinase 3/*genetics
Benzothiazoles/pharmacology ; Cell Line, Tumor ; DNA Mutational Analysis ; Drug Resistance, Neoplasm/genetics ; Humans ; Leukemia, Myeloid, Acute/metabolism ; Models, Molecular ; Molecular Structure ; Phenylurea Compounds/pharmacology ; Protein Binding ; Protein Structure, Tertiary/genetics ; Recurrence ; Reproducibility of Results ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Tytuł:
A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias.
Autorzy:
Pratz KW; Division of Hematologic Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA. />Cho E
Levis MJ
Karp JE
Gore SD
McDevitt M
Stine A
Zhao M
Baker SD
Carducci MA
Wright JJ
Rudek MA
Smith BD
Pokaż więcej
Źródło:
Leukemia [Leukemia] 2010 Aug; Vol. 24 (8), pp. 1437-44. Date of Electronic Publication: 2010 Jun 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Benzenesulfonates/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Pyridines/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/pharmacology ; Benzenesulfonates/pharmacokinetics ; Benzenesulfonates/pharmacology ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors ; Female ; Humans ; Leukemia, Myeloid, Acute/blood ; Male ; Middle Aged ; Niacinamide/analogs & derivatives ; Phenylurea Compounds ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacokinetics ; Pyridines/pharmacology ; Recurrence ; Sorafenib ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells.
Autorzy:
Kajiguchi T; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. />Chung EJ
Lee S
Stine A
Kiyoi H
Naoe T
Levis MJ
Neckers L
Trepel JB
Pokaż więcej
Źródło:
Leukemia [Leukemia] 2007 Dec; Vol. 21 (12), pp. 2476-84. Date of Electronic Publication: 2007 Sep 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Leukemic*
Active Transport, Cell Nucleus/*physiology
Leukemia, Myeloid/*metabolism
Neoplasm Proteins/*physiology
Protein Processing, Post-Translational/*physiology
Transcription, Genetic/*physiology
beta Catenin/*metabolism
fms-Like Tyrosine Kinase 3/*physiology
Acute Disease ; Animals ; Cell Line, Tumor ; Glycogen Synthase Kinase 3/antagonists & inhibitors ; Glycogen Synthase Kinase 3/physiology ; Glycogen Synthase Kinase 3 beta ; Humans ; Interleukin-3/pharmacology ; Leukemia, Myeloid/genetics ; Leukemia, Myeloid/pathology ; Membrane Proteins/pharmacology ; Mice ; Neoplasm Proteins/antagonists & inhibitors ; Phosphorylation ; Phosphotyrosine/metabolism ; RNA, Small Interfering/pharmacology ; Recombinant Proteins/metabolism ; Staurosporine/analogs & derivatives ; Staurosporine/pharmacology ; Tyrphostins/pharmacology ; beta Catenin/genetics ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors ; fms-Like Tyrosine Kinase 3/genetics
Czasopismo naukowe
    Wyświetlanie 1-11 z 11

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