Autor: "Levy, Daniel" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study.
Autorzy:: Keshawarz A; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Bui H; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Joehanes R; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Ma J; Framingham Heart Study, Framingham, MA, USA.; Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Liu C; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Huan T; Framingham Heart Study, Framingham, MA, USA.; Department of Ophthalmology and Visual Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Hwang SJ; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Tejada B; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Sooda M; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Courchesne P; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Munson PJ; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Demirkale CY; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA.
Yao C; Framingham Heart Study, Framingham, MA, USA.
Heard-Costa NL; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
Pitsillides AN; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Lin H; Framingham Heart Study, Framingham, MA, USA.; Division of Clinical Informatics, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Liu CT; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Wang Y; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Peloso GM; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Lundin J; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Haessler J; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Du Z; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Cho M; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hersh CP; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Castaldi P; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; General Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wen J; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Li Y; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Reiner AP; Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Feolo M; National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD, USA.
Sharopova N; National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD, USA.
Vasan RS; Framingham Heart Study, Framingham, MA, USA.; Department of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, USA.
DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Kooperberg C; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Levy D; Framingham Heart Study, Framingham, MA, USA. .; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 10; Vol. 13 (1), pp. 12952. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: DNA Methylation*
Cardiovascular Diseases*/genetics
Humans ; Female ; Quantitative Trait Loci ; Gene Expression Regulation ; Longitudinal Studies ; CpG Islands/genetics ; Genome-Wide Association Study

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Skocz do pozycji: 2.

Tytuł:: Integrative Mendelian randomization reveals the soluble receptor for advanced glycation end products as protective in relation to rheumatoid arthritis.
Autorzy:: Lee GY; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.
Yao C; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.
Hwang SJ; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.
Ma J; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.; School of Nutrition Science and Policy, Tufts University, Boston, USA.
Joehanes R; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.
Lee DH; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.
Ellison RC; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.; Boston University School of Medicine, Boston, MA, USA.
Moore LL; Boston University School of Medicine, Boston, MA, USA.
Liu C; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA.; School of Public Health, Boston University, Boston, MA, USA.
Levy D; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. .; Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA, 01702, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 May 17; Vol. 13 (1), pp. 8002. Date of Electronic Publication: 2023 May 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: Arthritis, Rheumatoid*/genetics
Cardiovascular Diseases*/complications
Humans ; Receptor for Advanced Glycation End Products/genetics ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Polymorphism, Single Nucleotide ; Glycation End Products, Advanced

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Skocz do pozycji: 3.

Tytuł:: Integrative analysis of clinical and epigenetic biomarkers of mortality.
Autorzy:: Huan T; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Department of Ophthalmology and Visual Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Nguyen S; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Colicino E; Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Ochoa-Rosales C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Centro de Vida Saludable de la Universidad de Concepción, Concepción, Chile.
Hill WD; Department of Psychology, Lothian Birth Cohorts, University of Edinburgh, Edinburgh, UK.
Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
Soerensen M; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Biochemistry and Pharmacology, Center for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
Zhang Y; Division of Clinical Epidemiology & Aging Research, German Cancer Rsrch Ctr (DKFZ), Heidelberg, Germany.
Baldassari A; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Elhadad MA; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Toshiko T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA.
Zheng Y; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Domingo-Relloso A; Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institute, Madrid, Spain.; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.; Department of Statistics and Operations Research, University of Valencia, Valencia, Spain.
Lee DH; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ma J; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Nutrition Epidemiology and Data Science, Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Yao C; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Hwang SJ; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Joehanes R; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Fornage M; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Bressler J; Department of Internal Medicine, Erasmus, Rotterdam, the Netherlands.
van Meurs JBJ; Department of Internal Medicine, Erasmus, Rotterdam, the Netherlands.
Debrabant B; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.
Mengel-From J; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
Hjelmborg J; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.
Christensen K; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
Vokonas P; Veterans Affairs, Normative Aging Study, Boston, Massachusetts, USA.; Veterans Affairs, Boston Healthcare System, Boston, Massachusetts, USA.; Boston University School of Public Health, Boston, Massachusetts, USA.
Schwartz J; Departments of Environmental Health and Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
Gahrib SA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Department of Psychology, Univ of Edinburgh, Edinburgh, UK.
Sotoodehnia N; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
Sitlani CM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
Kunze S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Neuherberg, Germany.; Institute of Medical Information Sciences, Biometry and Epidemiology, Ludwig-Maximilians-University, Munich, Germany.
Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Deary IJ; Division of Pulmonary, Critical Care and Sleep Medicine, Center for Lung Biology, University of Washington, Seattle, Washington, USA.
Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA.
Qu Y; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Greenland P; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Lloyd-Jones DM; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Bandinelli S; Geriatric Unit, LHATC (Local Health Authorities Tuscany Centre), Florence, Italy.
Voortman T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Hermann B; Division of Clinical Epidemiology & Aging Research, German Cancer Rsrch Ctr (DKFZ), Heidelberg, Germany.; Network Aging Research (NAR), University of Heidelberg, Heidelberg, Germany.
Baccarelli A; Precision Medicine Program, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
Whitsel E; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.; Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Pankow JS; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Levy D; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2022 Jun; Vol. 21 (6), pp. e13608. Date of Electronic Publication: 2022 May 12.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:: Cardiovascular Diseases*/genetics
Neoplasms*/genetics
Biomarkers ; DNA Methylation/genetics ; Epigenesis, Genetic ; Epigenomics ; Humans ; Male

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Skocz do pozycji: 4.

Tytuł:: Cardiovascular disease protein biomarkers are associated with kidney function: The Framingham Heart Study.
Autorzy:: Keshawarz A; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Framingham Heart Study, Framingham, Massachusetts, United States of America.
Hwang SJ; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Framingham Heart Study, Framingham, Massachusetts, United States of America.
Lee GY; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Framingham Heart Study, Framingham, Massachusetts, United States of America.
Yu Z; Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland, United States of America.
Yao C; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Framingham Heart Study, Framingham, Massachusetts, United States of America.
Köttgen A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Levy D; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Framingham Heart Study, Framingham, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 May 11; Vol. 17 (5), pp. e0268293. Date of Electronic Publication: 2022 May 11 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
MeSH Terms:: Cardiovascular Diseases*
Renal Insufficiency, Chronic*
Biomarkers ; Blood Proteins ; Cross-Sectional Studies ; Extracellular Matrix Proteins ; Female ; Glomerular Filtration Rate ; Humans ; Kidney ; Longitudinal Studies ; Male

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Skocz do pozycji: 5.

Tytuł:: Association of 71 cardiovascular disease-related plasma proteins with pulmonary function in the community.
Autorzy:: McNeill JN; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Lee DH; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Hwang SJ; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Courchesne P; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Yao C; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Huan T; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Joehanes R; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
O'Connor GT; Pulmonary Center, Boston University, Boston, Massachusetts, United States of America.
Ho JE; Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
Levy D; The Framingham Heart Study, Framingham, Massachusetts, and the Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Apr 07; Vol. 17 (4), pp. e0266523. Date of Electronic Publication: 2022 Apr 07 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cardiovascular Diseases*
Adult ; Blood Proteins ; Cross-Sectional Studies ; Forced Expiratory Volume/physiology ; Humans ; Inflammation ; Lung ; Spirometry ; Vital Capacity/physiology

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Skocz do pozycji: 6.

Tytuł:: Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs.
Autorzy:: Castellani CA; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Longchamps RJ; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sumpter JA; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Newcomb CE; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lane JA; Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, MN, USA.
Grove ML; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Bressler J; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Floyd JS; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Wang P; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Tin A; Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Coresh J; Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Pankow JS; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Fornage M; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Guallar E; Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
O'Rourke B; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, MN, USA.
Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Levy D; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Sotoodehnia N; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Arking DE; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Pokaż więcej
Źródło:: Genome medicine [Genome Med] 2020 Sep 28; Vol. 12 (1), pp. 84. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: CpG Islands*
DNA Copy Number Variations*
DNA Methylation*
DNA, Mitochondrial*
Cardiovascular Diseases/*genetics
Cardiovascular Diseases/*mortality
Mitochondria/*genetics
Cross-Sectional Studies ; DNA-Binding Proteins/genetics ; Disease Susceptibility ; Gene Expression ; Gene Knockdown Techniques ; Genome-Wide Association Study ; Humans ; Mitochondrial Proteins/genetics ; Odds Ratio ; Phenotype ; Polymorphism, Single Nucleotide ; Prognosis ; Quantitative Trait Loci ; Signal Transduction ; Transcription Factors/genetics

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Skocz do pozycji: 7.

Tytuł:: Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.
Autorzy:: Shu L; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Chan KHK; Departments of Epidemiology and Medicine and Center for Global Cardiometabolic Health, Brown University, Providence, RI, United States of America.; Hong Kong Institute of Diabetes and Obesity, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.
Zhang G; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Huan T; The Framingham Heart Study, Framingham, MA, USA and the Population Sciences Branch, National Heart, Lung, and Blood Institute, Bethesda, MD, United States of America.
Kurt Z; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Zhao Y; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Codoni V; Sorbonne Universités, UPMC Univ. Paris 06, INSERM, UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.
Trégouët DA; Sorbonne Universités, UPMC Univ. Paris 06, INSERM, UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.
Yang J; Department of Public Health, Hangzhou Normal University School of Medicine, Hangzhou, China.; Collaborative Innovation Center for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, United States of America.
Luo X; Department of Biostatistics, Brown University, Providence, RI, United States of America.
Levy D; The Framingham Heart Study, Framingham, MA, USA and the Population Sciences Branch, National Heart, Lung, and Blood Institute, Bethesda, MD, United States of America.
Lusis AJ; Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States of America.
Liu S; Departments of Epidemiology and Medicine and Center for Global Cardiometabolic Health, Brown University, Providence, RI, United States of America.; Department of Endocrinology, Guangdong General Hospital/Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Yang X; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.; Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, CA, United States of America.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, United States of America.; Pokaż więcej
Corporate Authors:: Cardiogenics Consortium
Źródło:: PLoS genetics [PLoS Genet] 2017 Sep 28; Vol. 13 (9), pp. e1007040. Date of Electronic Publication: 2017 Sep 28 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Gene Regulatory Networks*
Cardiovascular Diseases/*genetics
Diabetes Mellitus, Type 2/*genetics
Ethnicity/*genetics
Adipocytes/metabolism ; Amino Acids, Branched-Chain/metabolism ; Animals ; Caveolin 1/genetics ; Caveolin 1/metabolism ; Disease Models, Animal ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Gene Expression Regulation ; Genome-Wide Association Study ; Glucose/metabolism ; Glycoproteins/genetics ; Glycoproteins/metabolism ; Humans ; Hydroxymethylglutaryl CoA Reductases/genetics ; Hydroxymethylglutaryl CoA Reductases/metabolism ; Insulin-Like Growth Factor I/genetics ; Insulin-Like Growth Factor I/metabolism ; Lipid Metabolism ; Male ; Mice ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; Reproducibility of Results ; United States

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors.
Autorzy:: McManus DD; Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA. .; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA. .; Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA. .; 55 Lake Avenue North, Worcester, MA, 01655, USA. .
Rong J; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Neurology Division, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Huan T; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch and Division of Intramural Research, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MA, USA.
Lacey S; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Tanriverdi K; Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Munson PJ; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA.
Larson MG; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Mathematics and Statistics, Boston University, Boston, MA, USA.
Joehanes R; Population Sciences Branch and Division of Intramural Research, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MA, USA.; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA.; Hebrew SeniorLife, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Murthy V; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Shah R; Cardiology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Freedman JE; Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Levy D; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch and Division of Intramural Research, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MA, USA.; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2017 Feb 08; Vol. 18 (1), pp. 139. Date of Electronic Publication: 2017 Feb 08.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural
MeSH Terms:: Transcriptome*
Cardiovascular Diseases/*genetics
MicroRNAs/*metabolism
RNA, Messenger/*metabolism
Adult ; Aged ; Cardiovascular Diseases/etiology ; Cohort Studies ; Databases, Genetic ; Female ; Gene Expression Profiling ; Humans ; Logistic Models ; Male ; MicroRNAs/blood ; MicroRNAs/genetics ; Middle Aged ; Phenotype ; Prospective Studies ; RNA, Messenger/blood ; RNA, Messenger/genetics ; Risk Factors

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Whole blood gene expression and atrial fibrillation: the Framingham Heart Study.
Autorzy:: Lin H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America.
Yin X; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America.
Lunetta KL; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Dupuis J; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
McManus DD; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Cardiology Division, Department of Medicine, and Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Lubitz SA; Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.
Magnani JW; Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Joehanes R; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, Maryland, United States of America; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Munson PJ; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, Maryland, United States of America; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Larson MG; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, United States of America.
Levy D; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America.
Benjamin EJ; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, United States of America; Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America; Section of Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 May 07; Vol. 9 (5), pp. e96794. Date of Electronic Publication: 2014 May 07 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Genome, Human*
Atrial Fibrillation/*genetics
Cardiovascular Diseases/*genetics
Aged ; Atrial Fibrillation/blood ; Atrial Fibrillation/pathology ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/pathology ; Epistasis, Genetic/genetics ; Female ; Gene Expression Profiling ; Humans ; Male ; Middle Aged ; Risk Factors ; Signal Transduction/genetics