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Wyświetlanie 1-14 z 14
Tytuł:
A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART.
Autorzy:
O'Connor MA; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Munson PV; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Dross SE; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Tunggal HC; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Lewis TB; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Osborn J; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
Peterson CW; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA.; Department of Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Huang MW; Department of Laboratory Medicine and Pathology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Moats C; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.; Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA.
Smedley J; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.; Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA.
Jerome KR; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA.; Department of Laboratory Medicine and Pathology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Kiem HP; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA.; Department of Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Bagley KC; Profectus Biosciences Inc., 6411 Beckley Street, Baltimore, MD 21224, USA.
Mullins JI; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.
Fuller DH; Department of Microbiology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.; Washington National Primate Research Center, 1705 NE Pacific Street, Seattle, WA 98195, USA.
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Źródło:
Viruses [Viruses] 2021 Aug 14; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Homeostasis*
Sustained Virologic Response*
Anti-Retroviral Agents/*therapeutic use
Gastrointestinal Tract/*immunology
Simian Acquired Immunodeficiency Syndrome/*immunology
Simian Immunodeficiency Virus/*immunology
T-Lymphocytes, Regulatory/*immunology
Th17 Cells/*immunology
Acute Disease ; Animals ; Gastrointestinal Tract/physiopathology ; Immunity, Mucosal/drug effects ; Immunity, Mucosal/immunology ; Intraepithelial Lymphocytes/immunology ; Kinetics ; Macaca mulatta ; Male ; Models, Animal ; Simian Immunodeficiency Virus/pathogenicity ; Viral Load/drug effects ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł:
Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy.
Autorzy:
Lewis TB; Department of Cell Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. travis.lewis@uphs.upenn.edu.
Glasgow JN; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
Harms AS; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
Standaert DG; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. .
Curiel DT; Department of Radiation Oncology, School of Medicine, Washington University in St. Louis, St. Louis, MO 63108, USA. .
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Źródło:
Viruses [Viruses] 2014 Aug 21; Vol. 6 (8), pp. 3293-310. Date of Electronic Publication: 2014 Aug 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Transduction, Genetic*
Viral Tropism*
Adenoviridae/*physiology
Capsid Proteins/*metabolism
Genetic Therapy/*methods
Organisms, Genetically Modified/*physiology
Parkinson Disease/*therapy
Adenoviridae/genetics ; Animals ; Brain/virology ; Capsid Proteins/genetics ; Cell Line ; Mice ; Neurons/virology ; Organisms, Genetically Modified/genetics
Czasopismo naukowe
Tytuł:
Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy.
Autorzy:
Lewis TB; Department of Cell Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Glasgow JN
Glandon AM
Curiel DT
Standaert DG
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Źródło:
PloS one [PLoS One] 2010 Sep 17; Vol. 5 (9). Date of Electronic Publication: 2010 Sep 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Transduction, Genetic*
Viral Tropism*
Adenoviridae/*physiology
Brain/*metabolism
Dopamine/*metabolism
Parkinson Disease/*genetics
Parkinson Disease/*therapy
Receptors, Virus/*genetics
Adenoviridae/genetics ; Animals ; Brain/virology ; Coxsackie and Adenovirus Receptor-Like Membrane Protein ; Disease Models, Animal ; Dopamine/genetics ; Gene Expression ; Genetic Therapy ; Genetic Vectors/genetics ; Genetic Vectors/physiology ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/metabolism ; Neurons/virology ; Parkinson Disease/metabolism ; Protein Binding ; Receptors, Virus/metabolism ; Receptors, Virus/therapeutic use
Czasopismo naukowe
    Wyświetlanie 1-14 z 14

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