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Tytuł:
Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosis.
Autorzy:
Lu QJ; Traditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Li JY; School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Lin HX; Traditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Cai YS; Traditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Liu CS; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou, China.
Fu LP; Nanfang Hospital of Southern Medical University, Guangzhou, China.
Liu G; Nanfang Hospital of Southern Medical University, Guangzhou, China.
Yuan LX; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, Southern Medical University, Guangzhou, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1606-1615.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Arthritis, Experimental*/drug therapy
Arthritis, Rheumatoid*/drug therapy
Arthritis, Rheumatoid*/metabolism
Drugs, Chinese Herbal*/pharmacology
Gastrointestinal Microbiome*/drug effects
Animals ; Male ; RNA, Ribosomal, 16S/genetics ; Rats ; Rats, Sprague-Dawley ; Synovial Membrane/metabolism
Czasopismo naukowe
Tytuł:
Apatinib combined with Keytruda treatment induces apoptosis of gastric carcinoma cells through CES4/miR-616-5p/DUSP2 axis.
Autorzy:
Zhang F; Department of Traditional Chinese and Western Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yin Y; Department of Oncology, First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China.
Xu W; The Graduate School, Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China.
Zhou Z; Department of Traditional Chinese and Western Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Sun X; Department of Traditional Chinese and Western Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Li P; Department of Traditional Chinese and Western Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
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Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2021 Nov; Vol. 129 (5), pp. 345-356. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Apoptosis/*drug effects
Stomach Neoplasms/*drug therapy
Antibodies, Monoclonal, Humanized/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Carboxylic Ester Hydrolases/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Dual Specificity Phosphatase 2/genetics ; Gene Knockdown Techniques ; Humans ; MicroRNAs/genetics ; Pyridines/administration & dosage ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Ski promotes proliferation and inhibits apoptosis in fibroblasts under high-glucose conditions via the FoxO1 pathway.
Autorzy:
Peng Y; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Xiong RP; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhang ZH; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Ning YL; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhao Y; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Tan SW; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhou YG; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Li P; Department of Army Occupational Disease, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
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Źródło:
Cell proliferation [Cell Prolif] 2021 Feb; Vol. 54 (2), pp. e12971. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Glucose/*pharmacology
Nerve Tissue Proteins/*metabolism
Proto-Oncogene Proteins/*metabolism
Acetylation/drug effects ; Animals ; Cells, Cultured ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Histone Deacetylase 1/antagonists & inhibitors ; Histone Deacetylase 1/genetics ; Histone Deacetylase 1/metabolism ; Male ; Nerve Tissue Proteins/antagonists & inhibitors ; Nerve Tissue Proteins/genetics ; Phosphorylation/drug effects ; Proliferating Cell Nuclear Antigen/metabolism ; Proto-Oncogene Proteins/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; Rats ; Rats, Sprague-Dawley ; Smad2 Protein ; Smad3 Protein/metabolism
Czasopismo naukowe
Tytuł:
Naringin alleviates H 2 O 2 -induced apoptosis via the PI3K/Akt pathway in rat nucleus pulposus-derived mesenchymal stem cells.
Autorzy:
Nan LP; Department of Orthopedics, Dalian Medical University , Dalian, Liaoning, China.; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Wang F; Department of Orthopedics, Dalian Medical University , Dalian, Liaoning, China.; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Ran D; College of Veterinary Medicine, Yangzhou University , Yangzhou, China.
Zhou SF; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Liu Y; Department of Orthopedics, Dalian Medical University , Dalian, Liaoning, China.; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Zhang Z; Department of Orthopedics, Dalian Medical University , Dalian, Liaoning, China.; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Huang ZN; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Wang ZY; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Wang JC; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Feng XM; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
Zhang L; Department of Orthopedics, Clinical Medical College of Yangzhou University , Yangzhou, Jiangsu, China.
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Źródło:
Connective tissue research [Connect Tissue Res] 2020 Nov; Vol. 61 (6), pp. 554-567. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Flavanones/*pharmacology
Hydrogen Peroxide/*toxicity
Mesenchymal Stem Cells/*pathology
Nucleus Pulposus/*pathology
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Cell Survival/drug effects ; Flavanones/chemistry ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/ultrastructure ; Mitochondria/drug effects ; Mitochondria/pathology ; Mitochondria/ultrastructure ; Models, Biological ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
B7-H3 participates in human salivary gland epithelial cells apoptosis through NF-κB pathway in primary Sjögren's syndrome.
Autorzy:
Li P; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Yang Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Jin Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zhao R; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Dong C; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zheng W; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China.
Zhang T; Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226001, Jiangsu, People's Republic of China.
Li J; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China. .; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, People's Republic of China. .
Gu Z; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, 20th Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China. .; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, People's Republic of China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2019 Aug 14; Vol. 17 (1), pp. 268. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
B7 Antigens/*metabolism
Epithelial Cells/*metabolism
Epithelial Cells/*pathology
NF-kappa B/*metabolism
Salivary Glands/*pathology
Sjogren's Syndrome/*metabolism
Sjogren's Syndrome/*pathology
Aquaporin 5/metabolism ; B7 Antigens/blood ; Case-Control Studies ; Cell Proliferation ; Humans ; Middle Aged ; Sjogren's Syndrome/blood
Czasopismo naukowe
Tytuł:
Porphyromonas gingivalis induced inflammatory responses and promoted apoptosis in lung epithelial cells infected with H1N1 via the Bcl‑2/Bax/Caspase‑3 signaling pathway.
Autorzy:
Chen Y; School of Stomatology, Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Zhou R; Department of Stomatology, The Second Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Yi Z; Department of Stomatology, School of Stomatology, China Medical University, Shenyang, Liaoning 110002, P.R. China.
Li Y; Department of Pathogeny Biology, Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Fu Y; Department of Stomatology, The Second Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Zhang Y; Department of Pathogeny Biology, Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Li P; School of Stomatology, Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Li X; School of Stomatology, Jinzhou Medical University, Jinzhou, Liaoning 121000, P.R. China.
Pan Y; Department of Stomatology, School of Stomatology, China Medical University, Shenyang, Liaoning 110002, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2018 Jul; Vol. 18 (1), pp. 97-104. Date of Electronic Publication: 2018 May 07.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Influenza A Virus, H1N1 Subtype*
Porphyromonas gingivalis*
Signal Transduction*
Bacteroidaceae Infections/*metabolism
Caspase 3/*metabolism
Epithelial Cells/*metabolism
Influenza, Human/*metabolism
Lung/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
bcl-2-Associated X Protein/*metabolism
Bacteroidaceae Infections/pathology ; Bacteroidaceae Infections/virology ; Epithelial Cells/microbiology ; Epithelial Cells/virology ; Humans ; Inflammation/metabolism ; Inflammation/microbiology ; Inflammation/pathology ; Inflammation/virology ; Influenza, Human/microbiology ; Influenza, Human/pathology ; Lung/microbiology ; Lung/pathology ; Lung/virology
Czasopismo naukowe
Tytuł:
T-2 toxin induces apoptosis via the Bax-dependent caspase-3 activation in mouse primary Leydig cells.
Autorzy:
Zhang YF; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.; b College of Food and Bioengineering , Henan University of Science and Technology , Luoyang , China.
Su PK; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.; c The First Affiliated Hospital and College of Clinical Medicine , Henan University of Science and Technology , Luoyang , China.
Wang LJ; b College of Food and Bioengineering , Henan University of Science and Technology , Luoyang , China.
Zheng HQ; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.
Bai XF; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.
Li P; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.
Meng XP; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.
Yang JY; a College of Medical Technology and Engineering , Henan University of Science and Technology , Luoyang , China.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Jan; Vol. 28 (1), pp. 23-28. Date of Electronic Publication: 2017 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Caspase 3/*metabolism
Leydig Cells/*drug effects
T-2 Toxin/*toxicity
bcl-2-Associated X Protein/*metabolism
Animals ; Cell Proliferation/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Enzyme Activation ; Leydig Cells/enzymology ; Leydig Cells/pathology ; Male ; Mice ; Mitochondria/drug effects ; Mitochondria/enzymology ; Mitochondria/pathology ; Primary Cell Culture ; Signal Transduction/drug effects ; Time Factors
Czasopismo naukowe
Tytuł:
microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7.
Autorzy:
Wang X; Department of Endocrinology, Yuncheng Central Hospital, Yuncheng, Shanxi 044000, P.R. China.
Lin B; Henan University School of Basic Medical Sciences, Kaifeng, Henan 475004, P.R. China.
Nie L; Department of Endocrinology, Beijing Airport Hospital, Beijing 101318, P.R. China.
Li P; Department of Endocrinology, Yuncheng Central Hospital, Yuncheng, Shanxi 044000, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Oct; Vol. 16 (4), pp. 5667-5674. Date of Electronic Publication: 2017 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*
RNA Interference*
Apoptosis/*genetics
Glucose/*metabolism
MicroRNAs/*genetics
Podocytes/*metabolism
Sirtuins/*genetics
3' Untranslated Regions ; Animals ; Apoptosis/drug effects ; Caspase 3/metabolism ; Cell Line, Transformed ; Gene Knockdown Techniques ; Glucose/pharmacology ; Humans ; Mice
Czasopismo naukowe
Tytuł:
Blocking of stromal interaction molecule 1 expression influence cell proliferation and promote cell apoptosis in vitro and inhibit tumor growth in vivo in head and neck squamous cell carcinoma.
Autorzy:
Li P; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Bian XY; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.; Cardiopulmonary Function Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.
Chen Q; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.; Cardiopulmonary Function Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.
Yao XF; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Wang XD; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Zhang WC; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Tao YJ; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Jin R; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
Zhang L; Departments of Maxillofacial and Otorhinolaryngology Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, the People's Republic of China.; National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, the People's Republic of China.
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Źródło:
PloS one [PLoS One] 2017 May 11; Vol. 12 (5), pp. e0177484. Date of Electronic Publication: 2017 May 11 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Carcinoma, Squamous Cell/*physiopathology
Head and Neck Neoplasms/*physiopathology
Stromal Interaction Molecule 1/*genetics
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Blotting, Western ; Carcinoma, Squamous Cell/genetics ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Endoplasmic Reticulum Stress/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/genetics ; Head and Neck Neoplasms/genetics ; Humans ; Mice ; Mice, Nude ; Real-Time Polymerase Chain Reaction ; Squamous Cell Carcinoma of Head and Neck ; Stromal Interaction Molecule 1/metabolism ; Thapsigargin/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
DNase I aggravates islet β-cell apoptosis in type 2 diabetes.
Autorzy:
Zhu B; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.
Zhang L; Department of Pharmacy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. China.
Zhang YY; Department of Chinese Medicine, Beijing Hepingli Hospital, Beijing 100013, P.R. China.
Wang L; Department of Chinese Medicine, The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100050, P.R. China.
Li XG; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.
Liu T; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.
Fu YK; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.
Zheng YF; Department of Chinese Medicine, The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100050, P.R. China.
Li P; Department of Nephrology, China‑Japan Friendship Hospital, Beijing 100029, P.R. China.
Zhao ZG; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 Jun; Vol. 13 (6), pp. 4577-84. Date of Electronic Publication: 2016 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Deoxyribonuclease I/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Insulin-Secreting Cells/*metabolism
Adult ; Aged ; Biomarkers ; Blood Glucose ; Case-Control Studies ; Cell Line ; Deoxyribonuclease I/blood ; Deoxyribonuclease I/genetics ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/genetics ; Enzyme Activation ; Female ; Gene Expression ; Humans ; Immunohistochemistry ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
Geraniin induces apoptosis of human breast cancer cells MCF-7 via ROS-mediated stimulation of p38 MAPK.
Autorzy:
Zhai JW; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Gao C; d Peking University People's Hospital , Beijing , PR China.
Ma WD; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Wang W; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Yao LP; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Xia XX; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Luo M; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Zu YG; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
Fu YJ; a Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University , Harbin , PR China .; b Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University , Harbin , PR China .; c Collaborative Innovation Center for Development and Utilization of Forest Resources, Northeast Forestry University , Harbin , PR China .
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2016 Jun; Vol. 26 (5), pp. 311-8. Date of Electronic Publication: 2016 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Glucosides/*pharmacology
Hydrolyzable Tannins/*pharmacology
Reactive Oxygen Species/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Culture Techniques ; Cell Cycle/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Flow Cytometry ; Glucosides/isolation & purification ; Humans ; Hydrolyzable Tannins/isolation & purification ; MCF-7 Cells ; Membrane Potential, Mitochondrial/drug effects ; Time Factors
Czasopismo naukowe
Tytuł:
Overexpression of RBM5 induces autophagy in human lung adenocarcinoma cells.
Autorzy:
Su Z; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. su_.
Wang K; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Li R; Department of Urinary Surgery, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Yin J; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Hao Y; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Lv X; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Li J; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
Zhao L; Department of Pathophysiology, Norman Bethune College of Medicine of Jilin University, Changchun, Jilin, 130021, People's Republic of China. zhao_.
Du Y; Department of Pathophysiology, Norman Bethune College of Medicine of Jilin University, Changchun, Jilin, 130021, People's Republic of China. .
Li P; Department of Paediatrics, The Second Affiliated Hospital of Jilin University, Chuangchun, Jilin, 130041, People's Republic of China. .
Zhang J; Department of Respiratory Medicine, The Second Affiliated Hospital of Jilin University, Changchun, Jilin, 130041, People's Republic of China. .
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Źródło:
World journal of surgical oncology [World J Surg Oncol] 2016 Feb 29; Vol. 14, pp. 57. Date of Electronic Publication: 2016 Feb 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*pathology
Apoptosis/*drug effects
Autophagy/*drug effects
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*metabolism
Lung Neoplasms/*pathology
RNA-Binding Proteins/*metabolism
Tumor Suppressor Proteins/*metabolism
Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Animals ; Blotting, Western ; Cell Cycle Proteins/genetics ; DNA-Binding Proteins/genetics ; Female ; Humans ; Immunoenzyme Techniques ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured ; Tumor Suppressor Proteins/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
DBD-F induces apoptosis in gastric cancer-derived cells through suppressing HIF2α expression.
Autorzy:
Tong GH; Department of Laboratory Medicine, ShengJing Affiliated Hospital, China Medical University, Shenyang, 110004, China.
Tong WW; Department of Laboratory Medicine, ShengJing Affiliated Hospital, China Medical University, Shenyang, 110004, China.
Qin XS; Department of Laboratory Medicine, ShengJing Affiliated Hospital, China Medical University, Shenyang, 110004, China.
Lu LP; Department of Laboratory Medicine, ShengJing Affiliated Hospital, China Medical University, Shenyang, 110004, China.
Liu Y; Department of Laboratory Medicine, ShengJing Affiliated Hospital, China Medical University, Shenyang, 110004, China. liuyong_.
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2015 Dec; Vol. 38 (6), pp. 479-84. Date of Electronic Publication: 2015 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Basic Helix-Loop-Helix Transcription Factors/*biosynthesis
Oxazoles/*pharmacology
Stomach Neoplasms/*pathology
Sulfonamides/*pharmacology
Animals ; Blotting, Western ; Cell Line, Tumor ; Flow Cytometry ; Fluorescent Antibody Technique ; Humans ; Immunohistochemistry ; Mice ; Mice, Nude ; Reverse Transcriptase Polymerase Chain Reaction ; Transfection ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Effects of bleomycin A5 on caspase-3, P53, bcl-2 expression and telomerase activity in vascular endothelial cells.
Autorzy:
Huang YD; Department of Otorhinolaryngology, The 118 Hospital of Chinese PLA, Wenzhou, Zhejiang 325000, China.
Li P; Department of Otorhinolaryngology, General Hospital of Chengdu Military Region of PLA, Chengdu, Sichuan 610083, China.
Tong X; Department of Otorhinolaryngology, The First Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China 325000.
He Y; Department of Otorhinolaryngology, General Hospital of Chengdu Military Region of PLA, Chengdu, Sichuan 610083, China.
Zhuo Y; Department of Otorhinolaryngology, The 118 Hospital of Chinese PLA, Wenzhou, Zhejiang 325000, China.
Xia SW; Department of Otorhinolaryngology, The 118 Hospital of Chinese PLA, Wenzhou, Zhejiang 325000, China.
Luo XH; Department of Otorhinolaryngology, The 118 Hospital of Chinese PLA, Wenzhou, Zhejiang 325000, China.
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Źródło:
Indian journal of pharmacology [Indian J Pharmacol] 2015 Jan-Feb; Vol. 47 (1), pp. 55-8.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Bleomycin/*analogs & derivatives
Caspase 3/*metabolism
Enzyme Inhibitors/*pharmacology
Human Umbilical Vein Endothelial Cells/*drug effects
Proto-Oncogene Proteins c-bcl-2/*metabolism
Telomerase/*antagonists & inhibitors
Tumor Suppressor Protein p53/*metabolism
Bleomycin/toxicity ; Cells, Cultured ; Dose-Response Relationship, Drug ; Human Umbilical Vein Endothelial Cells/enzymology ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Signal Transduction/drug effects ; Telomerase/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł:
Water-soluble coenzyme q10 inhibits nuclear translocation of apoptosis inducing factor and cell death caused by mitochondrial complex I inhibition.
Autorzy:
Li H; Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan 75004, China. .
Chen G; Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan 75004, China. .
Ma W; Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan 75004, China. .
Li PA; Department of Pharmaceutical Sciences, Biomanufacturing Research Institute Biotechnology Enterprise (BRITE), North Carolina Central University, 1801 Fayetteville Street, Durham, NC 27707, USA. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2014 Jul 31; Vol. 15 (8), pp. 13388-400. Date of Electronic Publication: 2014 Jul 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Apoptosis Inducing Factor/*metabolism
Cell Nucleus/*metabolism
Electron Transport Complex I/*antagonists & inhibitors
Rotenone/*pharmacology
Ubiquinone/*analogs & derivatives
Animals ; Caspase 9/metabolism ; Cell Line ; Cytochromes c/metabolism ; Electron Transport Complex I/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/metabolism ; Reactive Oxygen Species/metabolism ; Ubiquinone/pharmacology ; Water/chemistry
Czasopismo naukowe
Tytuł:
Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells.
Autorzy:
Law BY; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Chan WK; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Xu SW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Wang JR; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Bai LP; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Liu L; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Wong VK; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
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Źródło:
Scientific reports [Sci Rep] 2014 Jul 01; Vol. 4, pp. 5510. Date of Electronic Publication: 2014 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alkaloids/*chemistry
Alkaloids/*pharmacology
Apoptosis/*drug effects
Apoptosis/*physiology
Autophagy/*drug effects
Autophagy/*physiology
HeLa Cells ; Humans ; Molecular Weight
Czasopismo naukowe
Tytuł:
Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells.
Autorzy:
Li P
Tian W
Ma X; College of Life Sciences, University of Chinese Academy of Sciences, No, 19A Yuquan Road, Beijing 100049, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2014 Jun 03; Vol. 13, pp. 138. Date of Electronic Publication: 2014 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Fatty Acid Synthase, Type I/*genetics
Protein Kinase Inhibitors/*pharmacology
Xanthones/*pharmacology
Apoptosis/genetics ; Cell Line, Tumor ; Fatty Acid Synthase, Type I/antagonists & inhibitors ; Fatty Acid Synthase, Type I/metabolism ; Female ; Focal Adhesion Kinase 1/antagonists & inhibitors ; Focal Adhesion Kinase 1/genetics ; Focal Adhesion Kinase 1/metabolism ; Humans ; Mammary Glands, Human/drug effects ; Mammary Glands, Human/metabolism ; Mammary Glands, Human/pathology ; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 3/genetics ; Mitogen-Activated Protein Kinase 3/metabolism ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
EGCG inhibits Cd(2+)-induced apoptosis through scavenging ROS rather than chelating Cd(2+) in HL-7702 cells.
Autorzy:
An Z; School of Life Sciences, Lanzhou University , Lanzhou, Gansu , China.
Qi Y
Huang D
Gu X
Tian Y
Li P
Li H
Zhang Y
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2014 May; Vol. 24 (4), pp. 259-67. Date of Electronic Publication: 2014 Jan 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Cadmium/*toxicity
Catechin/*analogs & derivatives
Reactive Oxygen Species/*metabolism
Cadmium/chemistry ; Catechin/pharmacology ; Cell Line ; Chelating Agents/chemistry ; Free Radical Scavengers/pharmacology ; Humans ; Liver/cytology ; Liver/drug effects ; Liver/metabolism ; Malondialdehyde/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Oxidative Stress/drug effects ; Proton Magnetic Resonance Spectroscopy ; Spectrophotometry, Ultraviolet
Czasopismo naukowe
Tytuł:
Inhibition of reverse-mode sodium-calcium exchanger activity and apoptosis by levosimendan in human cardiomyocyte progenitor cell-derived cardiomyocytes after anoxia and reoxygenation.
Autorzy:
Li PC; Department of Surgery, Division of Cardiovascular Surgery, China Medical University Hospital, Taichung, Taiwan ; Department of Life Science, Tunghai University, Taichung, Taiwan.
Yang YC; Department of Life sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan.
Hwang GY; Department of Life Science, Tunghai University, Taichung, Taiwan.
Kao LS; Department of Life sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan.
Lin CY; Clinical Immunology Center, China Medical University Hospital, Taichung, Taiwan ; College of Medicine, China Medical University, Taichung, Taiwan.
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Źródło:
PloS one [PLoS One] 2014 Feb 03; Vol. 9 (2), pp. e85909. Date of Electronic Publication: 2014 Feb 03 (Print Publication: 2014).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Hydrazones/*pharmacology
Myocytes, Cardiac/*drug effects
Pyridazines/*pharmacology
Sodium-Calcium Exchanger/*antagonists & inhibitors
Stem Cells/*drug effects
Adolescent ; Blotting, Western ; Cardiotonic Agents/pharmacology ; Cell Hypoxia ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cells, Cultured ; Child ; Endoplasmic Reticulum Stress/drug effects ; Female ; Flow Cytometry ; HEK293 Cells ; Humans ; Male ; Microscopy, Confocal ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Oxygen/pharmacology ; RNA Interference ; Simendan ; Sodium-Calcium Exchanger/genetics ; Sodium-Calcium Exchanger/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Thymic stromal lymphopoietin suppresses the apoptosis of decidual gamma-delta T cells via regulation of the signal transduction and activation of transcription 3/caspase-3 signaling pathway.
Autorzy:
Duan J; Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, China.
Jiang XP
Li MQ
Fan DX
Wang Y
Li DJ
Jin LP
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Źródło:
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2013 Dec; Vol. 70 (6), pp. 464-71. Date of Electronic Publication: 2013 Sep 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Signal Transduction*
Caspase 3/*metabolism
Cytokines/*metabolism
STAT3 Transcription Factor/*metabolism
T-Lymphocytes/*cytology
Adult ; Cytokines/immunology ; Female ; Humans ; Phosphorylation ; Pregnancy ; T-Lymphocytes/immunology ; Thymic Stromal Lymphopoietin
Czasopismo naukowe

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