- Tytuł:
-
Effect of metformin on cell proliferation,
apoptosis , migration and invasion in A172 glioma cells and its mechanisms. - Autorzy:
- Źródło:
- Molecular medicine reports [Mol Med Rep] 2019 Aug; Vol. 20 (2), pp. 887-894. Date of Electronic Publication: 2019 Jun 06.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Gene Expression Regulation, Neoplastic*
Antineoplastic Agents/*pharmacologyApoptosis /*drug effects
Hypoglycemic Agents/*pharmacology
Metformin/*pharmacology
Neuroglia/*drug effects
AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ;Apoptosis /genetics ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Malondialdehyde/agonists ; Malondialdehyde/metabolism ; Neuroglia/metabolism ; Neuroglia/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe