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Tytuł :
Luteolin attenuates hepatic injury in septic mice by regulating P2X7R-based HMGB1 release.
Autorzy :
Zhang ZH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Yang HX; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Jin Q; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Wu YL; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Cui ZY; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Shang Y; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Liu J; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Zhan ZY; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Lian LH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
Nan JX; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, Jilin Province 133002, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. .
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Źródło :
Food & function [Food Funct] 2021 Oct 04. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Metabolic profiling of nanosilver toxicity in the gills of common carp.
Autorzy :
Li QQ; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China; Yunnan International Joint Research Center for Hydro-Ecology Science & Engineering, Yunnan University, Kunming 650091, People's Republic of China.
Xiang QQ; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China; Yunnan International Joint Research Center for Hydro-Ecology Science & Engineering, Yunnan University, Kunming 650091, People's Republic of China.
Lian LH; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China.
Chen ZY; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China.
Luo X; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China; Yunnan International Joint Research Center for Hydro-Ecology Science & Engineering, Yunnan University, Kunming 650091, People's Republic of China.
Ding CZ; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China; Yunnan International Joint Research Center for Hydro-Ecology Science & Engineering, Yunnan University, Kunming 650091, People's Republic of China.
Chen LQ; Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of International Rivers and Trans-Boundary Eco-security, Yunnan University, Kunming 650091, People's Republic of China; Yunnan International Joint Research Center for Hydro-Ecology Science & Engineering, Yunnan University, Kunming 650091, People's Republic of China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Oct 01; Vol. 222, pp. 112548. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Carps*
Metal Nanoparticles*/toxicity
Animals ; Gills ; Metabolomics ; Silver/toxicity
Czasopismo naukowe
Tytuł :
Modulation of HMGB1 Release in APAP-Induced Liver Injury: A Possible Strategy of Chikusetsusaponin V Targeting NETs Formation.
Autorzy :
Liu J; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jiang M; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jin Q; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Wu YL; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Cui ZY; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Cui BW; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Shang Y; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Zhan ZY; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Lin YC; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jiao JY; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Piao MH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Zhang ZH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Sun RH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Nan JX; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.; Clinical Research Centre, Yanbian University Hospital, Yanji, China.
Lian LH; Key Laboratory of Traditional Chinese Korean Medicine Research (Yanbian University), State Ethnic Affairs Commission, Yanji, China.; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, China.; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
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Źródło :
Frontiers in pharmacology [Front Pharmacol] 2021 Jul 21; Vol. 12, pp. 723881. Date of Electronic Publication: 2021 Jul 21 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Parthenolide, bioactive compound of Chrysanthemum parthenium L., ameliorates fibrogenesis and inflammation in hepatic fibrosis via regulating the crosstalk of TLR4 and STAT3 signaling pathway.
Autorzy :
Cui ZY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Wang G; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Zhang J; Research and Development Center, Liaoning Shengjing Stem cell technology Co., Ltd, Shenyang, China.
Song J; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jiang YC; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Dou JY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Lian LH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Nan JX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.; Clinical Research Centre, Affiliated Hospital of Yanbian University, Yanji, China.
Wu YL; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Jul 12. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
[A case report of peri-left bundle branch pacing in a preschooler].
Autorzy :
Yang ZP; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Lin YZ; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Wu MQ; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Chen JQ; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Lian LH; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Liao XW; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Peng YM; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Zhang JC; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
Chen L; Division of Cardiology, Provincial Hospital of Fujian Medical University, Fuzhou 350001, China.
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Źródło :
Zhonghua xin xue guan bing za zhi [Zhonghua Xin Xue Guan Bing Za Zhi] 2021 Jan 11; Vol. 49 (1), pp. 74-76. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genus Gentiana: A review on phytochemistry, pharmacology and molecular mechanism.
Autorzy :
Jiang M; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. Electronic address: .
Cui BW; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. Electronic address: .
Wu YL; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. Electronic address: .
Nan JX; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China; Clinical Research Centre, Yanbian University Hospital, Yanji, Jilin Province 133002, China. Electronic address: .
Lian LH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jan 10; Vol. 264, pp. 113391. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gentiana*
Drugs, Chinese Herbal/*therapeutic use
Ethnopharmacology/*methods
Phytochemicals/*therapeutic use
Animals ; Cardiovascular Agents/isolation & purification ; Cardiovascular Agents/therapeutic use ; Drugs, Chinese Herbal/isolation & purification ; Ethnopharmacology/trends ; Gastrointestinal Agents/isolation & purification ; Gastrointestinal Agents/therapeutic use ; Humans ; Phytochemicals/isolation & purification
Czasopismo naukowe
Tytuł :
Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis.
Autorzy :
Zhan ZY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Wu M; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Shang Y; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Jiang M; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Liu J; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Qiao CY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Ye H; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Lin YC; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Piao MH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Sun RH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Zhang ZH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Jiao JY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Wu YL; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
Nan JX; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China and Clinical Research Centre, Yanbian University Hospital, Yanji, Jilin Province 133002, China.
Lian LH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China. , College of Pharmacy, Yanbian University, Yanji, Jilin Province 133002, China.
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Źródło :
Food & function [Food Funct] 2021 Jan 07; Vol. 12 (1), pp. 362-372. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat/*adverse effects
Ethanol/*adverse effects
Fatty Liver, Alcoholic/*prevention & control
Pyroptosis/*drug effects
Quercetin/*analogs & derivatives
Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Binge Drinking/complications ; Cells, Cultured ; Central Nervous System Depressants/adverse effects ; Disease Models, Animal ; Fatty Liver, Alcoholic/etiology ; Humans ; Male ; Mice ; Mice, Inbred ICR ; Quercetin/pharmacology
Czasopismo naukowe
Tytuł :
Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages.
Autorzy :
Qiao CY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Li Y; Department of Physiology, Seoul National University College of Medicine, 03080, Seoul, Republic of Korea.
Shang Y; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Jiang M; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Liu J; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Zhan ZY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Ye H; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Lin YC; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Jiao JY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Sun RH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Zhang ZH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Piao MH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Wu YL; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Nan JX; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China. .; Clinical Research Centre, Yanbian University Hospital, Yanji, 133002, Jilin, China. .
Lian LH; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China. .
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Źródło :
Inflammopharmacology [Inflammopharmacology] 2020 Dec; Vol. 28 (6), pp. 1481-1493. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Biflavonoids/*pharmacology
Catechin/*pharmacology
Cathepsin B/*metabolism
Gout/*metabolism
Inflammasomes/*metabolism
Interleukin-1beta/*metabolism
Macrophages/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Proanthocyanidins/*pharmacology
Uric Acid/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Cytokines/metabolism ; Dinoprostone/metabolism ; Gout/drug therapy ; Inflammasomes/drug effects ; Inflammation/drug therapy ; Inflammation/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Neutrophils/drug effects ; Neutrophils/metabolism
Czasopismo naukowe
Tytuł :
P2X7R orchestrates the progression of murine hepatic fibrosis by making a feedback loop from macrophage to hepatic stellate cells.
Autorzy :
Jiang M; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Cui BW; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Wu YL; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Zhang Y; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Shang Y; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Liu J; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Yang HX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Qiao CY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Zhan ZY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Ye H; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Jin Q; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Nan JX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Clinical Research Center, Yanbian University Hospital, Yanji, Jilin Province, 133002, China. Electronic address: .
Lian LH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 22-32. Date of Electronic Publication: 2020 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical and Drug Induced Liver Injury/*metabolism
Hepatic Stellate Cells/*drug effects
Liver Cirrhosis/*metabolism
Macrophages, Peritoneal/*drug effects
Receptors, Purinergic P2X7/*metabolism
Animals ; Cell Culture Techniques ; Cell Line, Tumor ; Chemical and Drug Induced Liver Injury/pathology ; Disease Models, Animal ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Feedback, Physiological ; Hepatic Stellate Cells/metabolism ; Hepatic Stellate Cells/pathology ; Humans ; Liver Cirrhosis/pathology ; Macrophages, Peritoneal/metabolism ; Macrophages, Peritoneal/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Purinergic P2X Receptor Antagonists/pharmacology ; Pyridines/pharmacology ; Tetrazoles/pharmacology ; Thioacetamide/toxicity
Czasopismo naukowe
Tytuł :
Severe fundus lesions induced by ocular jellyfish stings: A case report.
Autorzy :
Zheng XY; Department of Ophthalmology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China.
Cheng DJ; Department of Nephrology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China.
Lian LH; Department of Ophthalmology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China.
Zhang RT; Department of Ophthalmology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China.
Yu XY; Department of Ophthalmology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China. .
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Źródło :
World journal of clinical cases [World J Clin Cases] 2020 Oct 06; Vol. 8 (19), pp. 4544-4549.
Typ publikacji :
Case Reports
Raport
Tytuł :
20 S -Protopanaxatriol Ameliorates Hepatic Fibrosis, Potentially Involving FXR-Mediated Inflammatory Signaling Cascades.
Autorzy :
Song J; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Cui ZY; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Lian LH; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Han X; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Hou LS; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Wang G; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Gao L; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Zhu Y; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Jiang YC; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Dou JY; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Hu ZH; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
Zhao YQ; Shenyang Pharmaceutical University, Shenyang 110016, China.
Nan JX; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.; Clinical Research Center, Affiliated Hospital of Yanbian University, Yanji, Jilin 133002, China.
Wu YL; Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin 133002, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Aug 05; Vol. 68 (31), pp. 8195-8204. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Liver Cirrhosis/*drug therapy
Plant Extracts/*administration & dosage
Receptors, Cytoplasmic and Nuclear/*immunology
Sapogenins/*administration & dosage
Animals ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Humans ; Interleukin-1beta/genetics ; Interleukin-1beta/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Panax/chemistry ; Plant Extracts/chemistry ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Interleukin-1 Type I/genetics ; Receptors, Interleukin-1 Type I/immunology ; Receptors, Purinergic P2X7/genetics ; Receptors, Purinergic P2X7/immunology ; Sapogenins/chemistry ; Signal Transduction
Czasopismo naukowe
Tytuł :
Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake.
Autorzy :
Yang HX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Shang Y; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Jin Q; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Wu YL; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Liu J; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Qiao CY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Zhan ZY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Ye H; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
Nan JX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.; Clinical Research Center, Yanbian University Hospital, Yanji 133002, China.
Lian LH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji 133002, China.
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Źródło :
Biomolecules & therapeutics [Biomol Ther (Seoul)] 2020 Jul 01; Vol. 28 (4), pp. 320-327.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
P2X7 receptor-targeted regulation by tetrahydroxystilbene glucoside in alcoholic hepatosteatosis: A new strategy towards macrophage-hepatocyte crosstalk.
Autorzy :
Zhang Y; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jiang M; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Cui BW; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jin CH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Wu YL; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Shang Y; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Yang HX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Wu M; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Liu J; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Qiao CY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Zhan ZY; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Ye H; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Zheng GH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Jin Q; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Lian LH; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.
Nan JX; Key Laboratory for Traditional Chinese Korean Medicine of Jilin Province, College of Pharmacy, Yanbian University, Yanji, China.; Clinical Research Center, Yanbian University Hospital, Yanji, China.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2020 Jun; Vol. 177 (12), pp. 2793-2811. Date of Electronic Publication: 2020 Feb 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophages*/metabolism
Receptors, Purinergic P2X7*
Adenosine Triphosphate ; Animals ; Glucosides ; Hepatocytes/metabolism ; Interleukin-1beta/metabolism ; Mice ; Mice, Inbred C57BL ; Stilbenes
Czasopismo naukowe
Tytuł :
Design, synthesis, and antifibrosis evaluation of 4-(benzo-[c][1,2,5]thiadiazol-5-yl)-3(5)-(6-methyl- pyridin-2-yl)pyrazole and 3(5)-(6-methylpyridin- 2-yl)-4-(thieno-[3,2,-c]pyridin-2-yl)pyrazole derivatives.
Autorzy :
Zhu WJ; College of Pharmacy, Yanbian University, Yanji, 133002, PR China.
Cui BW; College of Pharmacy, Yanbian University, Yanji, 133002, PR China.
Wang HM; College of Pharmacy, Yanbian University, Yanji, 133002, PR China.
Nan JX; College of Pharmacy, Yanbian University, Yanji, 133002, PR China.
Piao HR; College of Pharmacy, Yanbian University, Yanji, 133002, PR China.
Lian LH; College of Pharmacy, Yanbian University, Yanji, 133002, PR China. Electronic address: .
Jin CH; College of Pharmacy, Yanbian University, Yanji, 133002, PR China; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Molecular Medicine Research Center, Yanbian University, Yanji, 133002, PR China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Oct 15; Vol. 180, pp. 15-27. Date of Electronic Publication: 2019 Jul 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Fibrosis/*drug therapy
Protein Kinase Inhibitors/*pharmacology
Pyrazoles/*pharmacology
Receptor, Transforming Growth Factor-beta Type I/*antagonists & inhibitors
Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Fibrosis/metabolism ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Phosphorylation/drug effects ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; Receptor, Transforming Growth Factor-beta Type I/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent manner.
Autorzy :
Han X; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Cui ZY; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Song J; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Piao HQ; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Lian LH; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Hou LS; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Wang G; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Zheng S; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Dong XX; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China.
Nan JX; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China; Clinical Research Center, Affiliated Hospital of Yanbian University, Yanji, Jilin Province, 133002, China. Electronic address: .
Wu YL; Key Laboratory for Natural Resource of ChangBai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin Province, 133002, China. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2019 Sep 25; Vol. 311, pp. 108794. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Diterpenes/*pharmacology
Lipogenesis/*drug effects
Liver X Receptors/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Alanine Transaminase/blood ; Animals ; Aspartate Aminotransferases/blood ; Body Weight/drug effects ; Cell Line ; Diet, High-Fat ; Diterpenes/chemistry ; Gene Expression Regulation/drug effects ; Liver X Receptors/agonists ; Liver X Receptors/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/pathology ; PPAR alpha/genetics ; PPAR alpha/metabolism ; Palmitic Acid/pharmacology ; Receptors, Cytoplasmic and Nuclear/antagonists & inhibitors ; Receptors, Cytoplasmic and Nuclear/genetics ; Signal Transduction/drug effects ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.
Autorzy :
Wang JY; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Wang Z; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Li MY; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Zhang Z; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Mi C; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Zuo HX; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Xing Y; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Wu YL; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Lian LH; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Xu GH; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Piao LX; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China.
Ma J; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China. Electronic address: .
Jin X; Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2018 Dec 25; Vol. 296, pp. 134-144. Date of Electronic Publication: 2018 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Movement/*drug effects
Epithelial-Mesenchymal Transition/*drug effects
Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors
Neoplasms/*drug therapy
Quinolines/*pharmacology
Snail Family Transcription Factors/*antagonists & inhibitors
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Cell Proliferation/drug effects ; Dictamnus/chemistry ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Neoplasms/diagnostic imaging ; Neoplasms/metabolism ; Neoplasms, Experimental/diagnostic imaging ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/metabolism ; Plant Roots/chemistry ; Quinolines/chemistry ; Quinolines/isolation & purification ; Signal Transduction/drug effects ; Snail Family Transcription Factors/metabolism ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Inhibition of P2X7R-NLRP3 Inflammasome Activation by Pleurotus citrinopileatus: A Possible Protective Role in Alcoholic Hepatosteatosis.
Autorzy :
Li X; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Jin Q; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Zhang Y; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Wu YL; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Jin CM; Analysis Center , Dt&CRO, Incorporated , Yongin-si , Gyeonggi-do 17042 , Republic of Korea.
Cui BW; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Li Y; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Jin MJ; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Shang Y; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Jiang M; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Yang HX; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Wu M; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Liu J; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Lian LH; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.
Nan JX; Key Laboratory for Natural Resource of Changbai Mountain and Functional Molecules, Ministry of Education, College of Pharmacy , Yanbian University , Yanji , Jilin 133002 , People's Republic of China.; Clinical Research Center , Yanbian University Hospital , Yanji , Jilin 133002 , People's Republic of China.
Pokaż więcej
Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2018 Dec 19; Vol. 66 (50), pp. 13183-13190. Date of Electronic Publication: 2018 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Liver, Alcoholic/*drug therapy
Inflammasomes/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*immunology
Pleurotus/*chemistry
Receptors, Purinergic P2X7/*immunology
AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/immunology ; Animals ; Fatty Liver, Alcoholic/genetics ; Fatty Liver, Alcoholic/immunology ; Fatty Liver, Alcoholic/metabolism ; Hep G2 Cells ; Humans ; Inflammasomes/genetics ; Liver/drug effects ; Liver/immunology ; Male ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Receptors, Purinergic P2X7/genetics ; Sirtuin 1/genetics ; Sirtuin 1/immunology ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/immunology ; Triglycerides/metabolism
Czasopismo naukowe

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