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Tytuł :
Involved free light chains <10 mg/L with treatment predict better outcomes in systemic light-chain amyloidosis.
Autorzy :
Godara A; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.; Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Toskic D; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Albanese J; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Rosenthal B; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Siddiqui NS; Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Kugelmass A; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Zhou P; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.
Fogaren T; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.; Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Varga C; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.; Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Landau HJ; Division of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York.
Comenzo RL; John Conant Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, Massachusetts.; Division of Hematology-Oncology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Jan; Vol. 96 (1), pp. E20-E23. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Clinical Trial; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunoglobulin Light-chain Amyloidosis*/blood
Immunoglobulin Light-chain Amyloidosis*/mortality
Immunoglobulin Light-chain Amyloidosis*/therapy
Immunoglobulin Light-chain Amyloidosis*/urine
Immunoglobulin Light Chains/*blood
Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Immunoglobulin Light Chains/urine ; Male ; Middle Aged ; Survival Rate
Raport
Tytuł :
Light-based technologies for management of COVID-19 pandemic crisis.
Autorzy :
Sabino CP; Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, SP, Brazil; BioLambda, Scientific and Commercial LTD, São Paulo, SP, Brazil. Electronic address: .
Ball AR; GAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA.
Baptista MS; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP, Brazil.. Electronic address: .
Dai T; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Hamblin MR; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa.
Ribeiro MS; Center for Lasers and Applications, Nuclear, and Energy Research Institute, National Commission for Nuclear Energy, São Paulo, SP, Brazil.
Santos AL; GAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA; Department of Chemistry Rice University, Houston, TX, USA; IdISBA - Fundación de Investigación Sanitaria de las Islas Baleares, Palma, Spain.
Sellera FP; Department of Internal Medicine, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil; School of Veterinary Medicine, Metropolitan University of Santos, Santos, Brazil.
Tegos GP; GAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA; Micromoria LLC, Marlborough, USA.
Wainwright M; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2020 Nov; Vol. 212, pp. 111999. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Light*
Coronavirus Infections/*therapy
Pneumonia, Viral/*therapy
Betacoronavirus/isolation & purification ; Betacoronavirus/radiation effects ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Humans ; Infrared Rays/therapeutic use ; Lasers, Solid-State/therapeutic use ; Low-Level Light Therapy ; Pandemics ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/therapeutic use ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
Bortezomib, Melphalan, Dexamethasone: A New Standard of Care for AL Amyloidosis?
Autorzy :
Pratt G; University Hospitals Birmingham, National Health Service Foundation Trust, Birmingham, United Kingdom.
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Źródło :
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2020 Oct 01; Vol. 38 (28), pp. 3243-3244. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Amyloidosis*/drug therapy
Immunoglobulin Light-chain Amyloidosis*/drug therapy
Bortezomib ; Dexamethasone ; Humans ; Immunoglobulin Light Chains ; Melphalan ; Standard of Care
Opinia redakcyjna
Tytuł :
Photoreaction Mechanisms of Flavoprotein Photoreceptors and Their Applications.
Autorzy :
Iwata T; Department of Pharmaceutical Sciences, Toho University, Funabashi, Chiba, Japan.
Masuda S; Department of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1293, pp. 189-206.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Light*
Optogenetics*
Flavoproteins/*metabolism
Flavoproteins/*radiation effects
Light Signal Transduction/*radiation effects
Cryptochromes/genetics ; Cryptochromes/metabolism ; Cryptochromes/radiation effects ; Flavoproteins/genetics
Czasopismo naukowe
Tytuł :
Advancing the fundamental understanding and practical applications of photo-bioelectrocatalysis.
Autorzy :
Grattieri M; Department of Chemistry, University of Utah, 315 S 1400 E Rm 2020, Salt Lake City, UT 84112, USA. .
Beaver K
Gaffney EM
Dong F
Minteer SD
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Aug 07; Vol. 56 (61), pp. 8553-8568. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Light*
Renewable Energy*
Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Catalysis ; Electrochemical Techniques ; Electron Transport ; Light-Harvesting Protein Complexes/chemistry ; Light-Harvesting Protein Complexes/metabolism ; Oxidation-Reduction ; Photosynthesis ; Proteobacteria/metabolism ; Quantum Theory ; Thylakoids/chemistry ; Thylakoids/metabolism
Czasopismo naukowe
Tytuł :
Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis.
Autorzy :
Radamaker L; Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Baur J; Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Huhn S; Medical Department V, Section of Multiple Myeloma, Heidelberg University Hospital, Heidelberg, Germany.
Haupt C; Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Hegenbart U; Medical Department V, Amyloidosis Center, Heidelberg University Hospital, Heidelberg, Germany.
Schönland S; Medical Department V, Amyloidosis Center, Heidelberg University Hospital, Heidelberg, Germany.
Bansal A; Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Schmidt M; Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Fändrich M; Institute of Protein Biochemistry, Ulm University, Ulm, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 08; Vol. 12 (1), pp. 875. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy*
Amyloid/*ultrastructure
Immunoglobulin Light-chain Amyloidosis/*metabolism
Amino Acid Sequence ; Female ; Humans ; Immunoglobulin Light Chains/metabolism ; Middle Aged ; Mutation/genetics ; Protein Aggregates ; Protein Conformation
Czasopismo naukowe
Tytuł :
Double recording system of Period1 gene expression rhythm in the olfactory bulb and liver in freely moving mouse.
Autorzy :
Hamada K; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan.
Oota A; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan.
Ito R; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan.
Kasahara S; Global Center for Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, 060-8012, Japan.
Nakajima K; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan.
Kikuchi Y; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan.
Sutherland K; Global Center for Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, 060-8012, Japan.
Ishikawa M; Global Center for Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, 060-8012, Japan; Faculty of Health Sciences, Hokkaido University, Sapporo, Hokkaido, 060-8638, Japan.
Shirato H; Global Center for Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, 060-8012, Japan; Department of Proton Beam Therapy, Research Center for Collaborative Projects, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, 060-8638, Japan.
Ozaki M; Department of Biological Response and Regulation, Faculty of Health Sciences, Hokkaido University, Sapporo, Hokkaido, 060-0812, Japan.
Hamada T; Department of Pharmaceutical Sciences, International University of Health and Welfare, Ohtawara, Tochigi, 324-8501, Japan; Department of Biological Response and Regulation, Faculty of Health Sciences, Hokkaido University, Sapporo, Hokkaido, 060-0812, Japan; Hakujikai Institute of Gerontology, 5-11-1, Shikahama, Adachi Ward, Tokyo, 123-0864, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Sep 03; Vol. 529 (4), pp. 898-903. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Light Signal Transduction*
Circadian Rhythm/*physiology
Liver/*physiology
Olfactory Bulb/*physiology
Period Circadian Proteins/*genetics
Suprachiasmatic Nucleus/*physiology
Animals ; Circadian Rhythm/radiation effects ; Electrodes, Implanted ; Gene Expression Regulation ; Genes, Reporter ; Light ; Liver/radiation effects ; Luciferases/genetics ; Luciferases/metabolism ; Mice ; Mice, Transgenic ; Movement/physiology ; Olfactory Bulb/radiation effects ; Optogenetics ; Period Circadian Proteins/metabolism ; Stereotaxic Techniques ; Suprachiasmatic Nucleus/radiation effects
Czasopismo naukowe
Tytuł :
A randomized blinded retrospective study: the combined use of micro-needling technique, low-level laser therapy and autologous non-activated platelet-rich plasma improves hair re-growth in patients with androgenic alopecia.
Autorzy :
Gentile P; Department of Surgical Sciences, Plastic and Reconstructive Surgery, University of Rome 'Tor Vergata' School of Medicine , Rome, Italy.
Dionisi L; Dionisi Law Firm , Rome, Italy.
Pizzicannella J; ASL02 Lanciano-Vasto Chieti, Ss. Annunziata Hospital , Chieti, Italy.
de Angelis B; Department of Surgical Sciences, Plastic and Reconstructive Surgery, University of Rome 'Tor Vergata' School of Medicine , Rome, Italy.
de Fazio D; Institute of Plastic Surgery, Galeazzi Hospital , Milan, Italy.
Garcovich S; Institute of Dermatology, F. Policlinico Gemelli IRCSS, Università Cattolica del Sacro Cuore , Rome, Italy.
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Źródło :
Expert opinion on biological therapy [Expert Opin Biol Ther] 2020 Sep; Vol. 20 (9), pp. 1099-1109. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Low-Level Light Therapy*
Alopecia/*therapy
Hair/*physiology
Platelet-Rich Plasma/*chemistry
Adult ; Aged ; Alopecia/pathology ; Alopecia/radiotherapy ; Female ; Hair/growth & development ; Humans ; Light ; Male ; Middle Aged ; Randomized Controlled Trials as Topic ; Regenerative Medicine ; Retrospective Studies ; Severity of Illness Index ; Transplantation, Autologous ; Young Adult
Czasopismo naukowe
Tytuł :
Mechanosensitivity is an essential component of phototransduction in vertebrate rods.
Autorzy :
Bocchero U; Neurobiology Department, International School for Advanced Studies, Trieste, Italy.
Falleroni F; Neurobiology Department, International School for Advanced Studies, Trieste, Italy.
Mortal S; Neurobiology Department, International School for Advanced Studies, Trieste, Italy.
Li Y; Neurobiology Department, International School for Advanced Studies, Trieste, Italy.
Cojoc D; Institute of Materials, National Research Council of Italy (CNR), Trieste, Italy.
Lamb T; Eccles Institute of Neuroscience, John Curtin School of Medical Research, The Australian National University, Canberra, Australia.
Torre V; Neurobiology Department, International School for Advanced Studies, Trieste, Italy.; Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Zhejiang, China.; Center of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou Institute of Systems Medicine, Suzhou Industrial Park, Suzhou, China.
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Źródło :
PLoS biology [PLoS Biol] 2020 Jul 15; Vol. 18 (7), pp. e3000750. Date of Electronic Publication: 2020 Jul 15 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Light Signal Transduction*/radiation effects
Mechanotransduction, Cellular*/radiation effects
Retinal Rod Photoreceptor Cells/*metabolism
Xenopus laevis/*metabolism
Animals ; Calcium/metabolism ; Fluorescence ; Light ; Multigene Family ; Photic Stimulation ; Retinal Rod Photoreceptor Cells/radiation effects ; TRPC Cation Channels/genetics ; Xenopus Proteins/genetics
Czasopismo naukowe
Tytuł :
Adjustment of photosynthetic activity to drought and fluctuating light in wheat.
Autorzy :
Grieco M; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.; Department of Genebank, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.
Roustan V; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Dermendjiev G; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Rantala S; Molecular Plant Biology, University of Turku, Turku, Finland.
Jain A; Applied Bioinformatics Group, Institute of Cell Biology and Neuroscience, Goethe-University Frankfurt, Frankfurt, Germany.
Leonardelli M; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Neumann K; Department of Genebank, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.
Berger V; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Engelmeier D; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Bachmann G; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.
Ebersberger I; Applied Bioinformatics Group, Institute of Cell Biology and Neuroscience, Goethe-University Frankfurt, Frankfurt, Germany.; Senckenberg Biodiversity and Climate Research Centre (S-BIK-F), Frankfurt, Germany.; LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany.
Aro EM; Molecular Plant Biology, University of Turku, Turku, Finland.
Weckwerth W; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.; Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria.
Teige M; Ecogenomics and Systems Biology, University of Vienna, Vienna, Austria.; Max Perutz Labs, Department of Biochemistry & Cell Biology, University of Vienna, Vienna, Austria.
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Źródło :
Plant, cell & environment [Plant Cell Environ] 2020 Jun; Vol. 43 (6), pp. 1484-1500. Date of Electronic Publication: 2020 Mar 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Droughts*
Light*
Photosynthesis/*radiation effects
Triticum/*physiology
Triticum/*radiation effects
Acclimatization/physiology ; Ecotype ; Light-Harvesting Protein Complexes/metabolism ; Phosphorylation/radiation effects ; Photosystem II Protein Complex/metabolism ; Stress, Physiological/radiation effects ; Triticum/growth & development
Czasopismo naukowe
Tytuł :
Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 Integrates Age and Light Signals to Negatively Regulate Leaf Senescence.
Autorzy :
Tian T; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China.
Ma L; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China.
Liu Y; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China.
Xu D; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China.
Chen Q; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China.
Li G; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an 271018, China .
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Źródło :
The Plant cell [Plant Cell] 2020 May; Vol. 32 (5), pp. 1574-1588. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Light Signal Transduction*/drug effects
Light Signal Transduction*/radiation effects
Arabidopsis/*metabolism
Arabidopsis/*radiation effects
Arabidopsis Proteins/*metabolism
Phytochrome/*metabolism
Plant Leaves/*growth & development
Plant Leaves/*radiation effects
Arabidopsis/drug effects ; Base Sequence ; Light ; Mutation/genetics ; Plant Leaves/drug effects ; Promoter Regions, Genetic ; Protein Binding/drug effects ; Protein Binding/radiation effects ; Salicylic Acid/pharmacology ; Transcription, Genetic/drug effects ; Transcription, Genetic/radiation effects
Czasopismo naukowe
Tytuł :
The utility of repeat kidney biopsy in systemic immunoglobulin light chain amyloidosis.
Autorzy :
Angel-Korman A; Renal Section, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Jaberi A; Renal Section, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Sanchorawala V; Section of Hematology and Oncology, Department of Medicine, Boston Medical Center, Boston, MA, USA.; Amyloidosis Center, Boston University School of Medicine, Boston, MA, USA.
Havasi A; Renal Section, Department of Medicine, Boston Medical Center, Boston, MA, USA.; Amyloidosis Center, Boston University School of Medicine, Boston, MA, USA.
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Źródło :
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2020 Mar; Vol. 27 (1), pp. 17-24. Date of Electronic Publication: 2019 Oct 09.
Typ publikacji :
Clinical Trial; Journal Article; Video-Audio Media
MeSH Terms :
Immunoglobulin Light-chain Amyloidosis*/pathology
Immunoglobulin Light-chain Amyloidosis*/therapy
Plaque, Amyloid*/pathology
Plaque, Amyloid*/therapy
Proteinuria*/pathology
Proteinuria*/therapy
Kidney/*pathology
Adult ; Aged ; Biopsy ; Female ; Humans ; Immunoglobulin Light Chains ; Male ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Cryptochrome-mediated blue-light signalling modulates UVR8 photoreceptor activity and contributes to UV-B tolerance in Arabidopsis.
Autorzy :
Tissot N; Department of Botany and Plant Biology, Section of Biology, Faculty of Sciences, University of Geneva, 30 Quai E. Ansermet, 1211, Geneva 4, Switzerland.; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland.
Ulm R; Department of Botany and Plant Biology, Section of Biology, Faculty of Sciences, University of Geneva, 30 Quai E. Ansermet, 1211, Geneva 4, Switzerland. .; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2020 Mar 12; Vol. 11 (1), pp. 1323. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptation, Physiological*/radiation effects
Light Signal Transduction*/radiation effects
Ultraviolet Rays*
Arabidopsis/*physiology
Arabidopsis/*radiation effects
Arabidopsis Proteins/*metabolism
Chromosomal Proteins, Non-Histone/*metabolism
Cryptochromes/*metabolism
Arabidopsis/genetics ; Gene Expression Regulation, Plant/radiation effects ; Hypocotyl/growth & development ; Hypocotyl/radiation effects ; Light ; Models, Biological ; Protein Multimerization/radiation effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Seedlings/metabolism ; Seedlings/radiation effects
Czasopismo naukowe
Tytuł :
Red-shifted chlorophyll a bands allow uphill energy transfer to photosystem II reaction centers in an aerial green alga, Prasiola crispa, harvested in Antarctica.
Autorzy :
Kosugi M; Department of Biological Sciences, Faculty of Science and Engineering, Chuo University, 1-13-27, Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan. Electronic address: .
Ozawa SI; Research Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan.
Takahashi Y; Research Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan.
Kamei Y; Department of Basic Biology, School of Life Sciences, SOKENDAI (The Graduate University for Advanced Studies), Nishigonaka 38, Myodaiji, Okazaki, Aichi 444-8585, Japan; National Institute for Basic Biology, National Institutes of Natural Sciences, 38 Nishigonaka, Myodaiji, Okazaki, Aichi 444-8585, Japan.
Itoh S; Department of Physics, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
Kudoh S; National Institute of Polar Research, Research Organization of Information and Systems, 10-3 Midori-cho, Tachikawa, Tokyo 190-8518, Japan; Department of Polar Science, School of Multidisciplinary Science, SOKENDAI (The Graduate University for Advanced Studies), 10-3 Midori-cho, Tachikawa, Tokyo 190-8518, Japan.
Kashino Y; Department of Life Science, University of Hyogo, 3-2-1 Kohto, Kamigohri, Ako-gun, Hyogo 678-1297, Japan.
Koike H; Department of Biological Sciences, Faculty of Science and Engineering, Chuo University, 1-13-27, Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan.
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Źródło :
Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2020 Feb 01; Vol. 1861 (2), pp. 148139. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Light*
Chlorophyll A/*metabolism
Chlorophyta/*metabolism
Photosystem II Protein Complex/*metabolism
Antarctic Regions ; Light-Harvesting Protein Complexes/metabolism ; Oxygen/metabolism ; Photosystem I Protein Complex/metabolism ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Towards a novel target therapy for renal diseases related to plasma cell dyscrasias: The example of AL amyloidosis.
Autorzy :
Roccatello D; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy. Electronic address: .
Fenoglio R; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Baldovino S; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Naretto C; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Ferro M; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Barreca A; Pathology Division, Department of Oncology, University of Turin, Italy.
Rossi D; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Sciascia S; Nephrology and Dialysis Unit-CMID, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hospital of Turin, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
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Źródło :
Autoimmunity reviews [Autoimmun Rev] 2020 Sep; Vol. 19 (9), pp. 102622. Date of Electronic Publication: 2020 Jul 12.
Typ publikacji :
Letter
MeSH Terms :
Antibodies, Monoclonal/*therapeutic use
Immunoglobulin Light-chain Amyloidosis/*drug therapy
Kidney Diseases/*drug therapy
Paraproteinemias/*drug therapy
Humans ; Immunoglobulin Light Chains ; Immunoglobulin Light-chain Amyloidosis/pathology ; Kidney/pathology ; Kidney Diseases/pathology ; Paraproteinemias/pathology
Opinia redakcyjna
Tytuł :
Daratumumab plus CyBorD for patients with newly diagnosed AL amyloidosis: safety run-in results of ANDROMEDA.
Autorzy :
Palladini G; Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Kastritis E; Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Maurer MS; Columbia University Irving Medical Center, New York, NY.
Zonder J; Barbara Ann Karmanos Cancer Institute, Detroit, MI.
Minnema MC; Department of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands.
Wechalekar AD; Division of Medicine, Faculty of Medical Sciences, University College London, London, United Kingdom.
Jaccard A; Centre Hospitalier Universitaire and Reference Center for AL Amyloidosis, Limoges, France.
Lee HC; Division of Cancer Medicine, Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX.
Bumma N; Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Kaufman JL; Winship Cancer Institute, Emory University, Atlanta, GA.
Medvedova E; Oregon Health & Science University, Portland, OR.
Kovacsovics T; Division of Hematology and Hematologic Malignancies, University of Utah School of Medicine, and the Huntsman Cancer Institute, Salt Lake City, UT.
Rosenzweig M; Department of Hematology and Hematopoietic Cell Transplantation, Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope, Duarte, CA.
Sanchorawala V; Department of Medicine and Amyloidosis Center, Boston University School of Medicine and Boston Medical Center, Boston, MA.
Qin X; Janssen Research & Development, LLC, Spring House, PA.
Vasey SY; Janssen Research & Development, LLC, Spring House, PA.
Weiss BM; Janssen Research & Development, LLC, Spring House, PA.
Vermeulen J; Janssen Research & Development, Leiden, The Netherlands; and.
Merlini G; Amyloidosis Research and Treatment Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Comenzo RL; Division of Hematology/Oncology, John C. Davis Myeloma and Amyloid Program, Tufts Medical Center, Boston, MA.
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Źródło :
Blood [Blood] 2020 Jul 02; Vol. 136 (1), pp. 71-80.
Typ publikacji :
Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Immunoglobulin Light-chain Amyloidosis/*drug therapy
Acute Kidney Injury/chemically induced ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Bortezomib/administration & dosage ; Bortezomib/adverse effects ; Cellulitis/chemically induced ; Cyclophosphamide/administration & dosage ; Cyclophosphamide/adverse effects ; Dexamethasone/administration & dosage ; Dexamethasone/adverse effects ; Female ; Follow-Up Studies ; Humans ; Immunoglobulin Heavy Chains/blood ; Immunoglobulin Light Chains/blood ; Immunoglobulin Light-chain Amyloidosis/blood ; Immunoglobulin Light-chain Amyloidosis/pathology ; Immunoglobulin Light-chain Amyloidosis/urine ; Male ; Middle Aged ; Nervous System/pathology ; Pneumonia/chemically induced ; Treatment Outcome ; Viscera/pathology
Czasopismo naukowe
Tytuł :
Alternative pathways control actomyosin contractility in epitheliomuscle cells during morphogenesis and body contraction.
Autorzy :
Holz O; Philipps University Marburg, Faculty of Biology, Morphology and Evolution of Invertebrates, D-35039 Marburg, Germany.
Apel D; Philipps University Marburg, Faculty of Biology, Morphology and Evolution of Invertebrates, D-35039 Marburg, Germany; DFG Research Training Group, Membrane Plasticity in Tissue Development and Remodeling, GRK 2213, Philipps-Universität Marburg, Germany.
Hassel M; Philipps University Marburg, Faculty of Biology, Morphology and Evolution of Invertebrates, D-35039 Marburg, Germany. Electronic address: .
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Źródło :
Developmental biology [Dev Biol] 2020 Jul 01; Vol. 463 (1), pp. 88-98. Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Actomyosin/*metabolism
Muscle Contraction/*physiology
Myosin Light Chains/*metabolism
Actin Cytoskeleton/metabolism ; Actomyosin/physiology ; Animals ; Cell Shape ; Epithelial Cells/metabolism ; Hydra/metabolism ; Myosin-Light-Chain Kinase/metabolism ; Myosin-Light-Chain Kinase/physiology ; Phosphorylation ; Signal Transduction ; Stress Fibers/metabolism ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Tytuł :
The impact of COVID-19 in the management of AL amyloidosis and Immunoglobulin Deposition Disease: A single-center experience.
Autorzy :
Lee H; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.
Tay J; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.; Charbonneau Cancer Research Institute, Calgary, AB, Canada.
Duggan P; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.
McCulloch S; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.
Neri P; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.; Charbonneau Cancer Research Institute, Calgary, AB, Canada.
Bahlis NJ; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.; Charbonneau Cancer Research Institute, Calgary, AB, Canada.
Jimenez-Zepeda VH; Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada.; Charbonneau Cancer Research Institute, Calgary, AB, Canada.
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Źródło :
European journal of haematology [Eur J Haematol] 2021 Mar; Vol. 106 (3), pp. 340-345. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/epidemiology
Pandemics*
SARS-CoV-2*
Immunoglobulin Light Chains/*analysis
Immunoglobulin Light-chain Amyloidosis/*drug therapy
Paraproteinemias/*drug therapy
Aged ; Alberta/epidemiology ; Antibodies, Monoclonal/therapeutic use ; Basement Membrane/immunology ; Basement Membrane/pathology ; Bortezomib/therapeutic use ; COVID-19 Testing/statistics & numerical data ; Cyclophosphamide/therapeutic use ; Dexamethasone/therapeutic use ; Disease Management ; Disease Susceptibility ; Drug Therapy, Combination ; Female ; Humans ; Immunoglobulin Light-chain Amyloidosis/mortality ; Kaplan-Meier Estimate ; Lenalidomide/therapeutic use ; Male ; Methylprednisolone/therapeutic use ; Middle Aged ; Neoplasm, Residual ; Paraproteinemias/mortality ; Precision Medicine ; Retrospective Studies ; Telemedicine
Czasopismo naukowe

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