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Wyszukujesz frazę ""Lim PL"" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł :
Repression of tau hyperphosphorylation by chronic endurance exercise in aged transgenic mouse model of tauopathies.
Autorzy :
Leem YH; Department of Chemistry and Nano Science, and Brain Disease Research Institute, Ewha Womans University, Seoul, Korea.
Lim HJ
Shim SB
Cho JY
Kim BS
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2009 Aug 15; Vol. 87 (11), pp. 2561-70.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging*
Physical Conditioning, Animal*/physiology
Tauopathies/*physiopathology
Tauopathies/*therapy
tau Proteins/*metabolism
Animals ; Brain/enzymology ; Brain/physiopathology ; Disease Models, Animal ; Female ; Hippocampus/physiopathology ; Humans ; Male ; Mice ; Mice, Transgenic ; Phosphorylation/physiology ; Signal Transduction/physiology ; Tauopathies/enzymology ; tau Proteins/genetics
Czasopismo naukowe
Tytuł :
Nordihydroguaiaretic acid induces astroglial death via glutathione depletion.
Autorzy :
Im JY; Division of Nano Sciences and Brain Disease Research Institute, Ewha Womans University, Seoul, Republic of Korea.
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2007 Nov 01; Vol. 85 (14), pp. 3127-34.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*pharmacology
Astrocytes/*drug effects
Cerebral Cortex/*cytology
Glutathione/*metabolism
Masoprocol/*pharmacology
Analysis of Variance ; Animals ; Cell Death/drug effects ; Dose-Response Relationship, Drug ; Drug Interactions ; Embryo, Mammalian ; Enzyme Inhibitors/pharmacology ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Neurons/drug effects ; Reactive Oxygen Species/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Optimization of chronic stress paradigms using anxiety- and depression-like behavioral parameters.
Autorzy :
Kim KS; Department of Neuroscience and Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Republic of Korea.
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2006 Feb 15; Vol. 83 (3), pp. 497-507.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anxiety/*diagnosis
Anxiety/*etiology
Behavior, Animal/*physiology
Depression/*diagnosis
Depression/*etiology
Stress, Physiological/*complications
Amygdala/metabolism ; Amygdala/physiopathology ; Analysis of Variance ; Animals ; Anxiety/genetics ; Chronic Disease ; Depression/genetics ; Disease Models, Animal ; Gene Expression ; Gene Expression Regulation ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Male ; Maze Learning/physiology ; Mice ; Mice, Inbred C57BL ; Oligonucleotide Array Sequence Analysis/methods ; RNA, Messenger/metabolism ; Restraint, Physical/methods ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Risk Assessment ; Risk Factors ; Stress, Physiological/genetics ; Stress, Physiological/pathology ; Time Factors
Czasopismo naukowe
Tytuł :
Cadmium-induced astroglial death proceeds via glutathione depletion.
Autorzy :
Im JY; Department of Neuroscience, Neuroscience Research Center and Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea.
Paik SG
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2006 Feb 01; Vol. 83 (2), pp. 301-8.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*drug effects
Cadmium/*pharmacology
Glutathione/*metabolism
Animals ; Animals, Newborn ; Antioxidants/pharmacology ; Cell Count/methods ; Cell Death/drug effects ; Cells, Cultured ; Cerebral Cortex/cytology ; Diamide/pharmacology ; Dose-Response Relationship, Drug ; Drug Interactions ; Extracellular Space/drug effects ; Glutathione/analogs & derivatives ; Glutathione/pharmacology ; Malates/pharmacology ; Mice ; Mice, Inbred ICR ; Time Factors
Czasopismo naukowe
Tytuł :
Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein.
Autorzy :
Lee KW; Department of Neuroscience, Ewha Institute of Neuroscience and Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea.
Lee SH
Kim H
Song JS
Yang SD
Paik SG
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2004 May 15; Vol. 76 (4), pp. 572-80.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*complications
Amyloid beta-Protein Precursor/*toxicity
Anxiety/*etiology
Cognition Disorders/*etiology
Alzheimer Disease/chemically induced ; Amyloid beta-Protein Precursor/biosynthesis ; Amyloid beta-Protein Precursor/genetics ; Analysis of Variance ; Animals ; Avoidance Learning/physiology ; Behavior, Animal ; Blotting, Northern/methods ; Blotting, Western/methods ; Disease Models, Animal ; Humans ; Immunohistochemistry/methods ; Maze Learning ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Motor Activity ; Mutation ; Oligonucleotide Array Sequence Analysis/methods ; Psychomotor Performance ; RNA, Messenger/biosynthesis ; Reaction Time ; Reverse Transcriptase Polymerase Chain Reaction/methods
Czasopismo naukowe
Tytuł :
Protective effects of extracellular glutathione against Zn2+-induced cell death in vitro and in vivo.
Autorzy :
Cho IH; Department of Neuroscience, Ewha Institute of Neuroscience and Medical Research Center, Ewha Womans University School of Medicine, Seoul, Korea.
Im JY
Kim D
Kim KS
Lee JK
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2003 Dec 01; Vol. 74 (5), pp. 736-43.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*drug effects
Glutathione/*pharmacology
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Zinc/*toxicity
Animals ; Astrocytes/pathology ; Cell Death/physiology ; Cells, Cultured ; Cerebral Cortex/drug effects ; Cerebral Cortex/pathology ; Excitatory Amino Acid Agonists/administration & dosage ; Excitatory Amino Acid Agonists/pharmacology ; Extracellular Fluid/chemistry ; Hippocampus/drug effects ; Hippocampus/pathology ; Injections, Intraventricular ; Kainic Acid/administration & dosage ; Kainic Acid/pharmacology ; Mice ; Neurons/pathology
Czasopismo naukowe
Tytuł :
Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice.
Autorzy :
Im JY; Department of Neuroscience, Ewha Institute of Neuroscience and Medical Research Center, Ewha Womans University School of Medicine, Seoul, Korea.
Lee KW
Kim MH
Lee SH
Ha HY
Cho IH
Kim D
Yu MS
Kim JB
Lee JK
Kim YJ
Youn BW
Yang SD
Shin HS
Han PL
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2003 Oct 15; Vol. 74 (2), pp. 326-32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing*
Brain Infarction/*enzymology
Brain Ischemia/*enzymology
Carrier Proteins/*metabolism
Mitogen-Activated Protein Kinases/*metabolism
Animals ; Brain Infarction/genetics ; Brain Infarction/pathology ; Brain Ischemia/genetics ; Brain Ischemia/pathology ; Carrier Proteins/genetics ; Female ; Infarction, Middle Cerebral Artery/enzymology ; Infarction, Middle Cerebral Artery/genetics ; JNK Mitogen-Activated Protein Kinases ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phosphorylation ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.
Autorzy :
Piao CS; Department of Anatomy, Inha University School of Medicine, Inchon, Korea.
Kim JB
Han PL
Lee JK
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Źródło :
Journal of neuroscience research [J Neurosci Res] 2003 Aug 15; Vol. 73 (4), pp. 537-44.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use
Brain Infarction/*prevention & control
Imidazoles/*therapeutic use
Mitogen-Activated Protein Kinases/*metabolism
Pyridines/*therapeutic use
Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Astrocytes/pathology ; Blotting, Western/methods ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Brain Infarction/metabolism ; Cyclooxygenase 2 ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Immunohistochemistry/methods ; Infarction, Middle Cerebral Artery/physiopathology ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Lectins/metabolism ; Male ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Mitogen-Activated Protein Kinase 14 ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Neurologic Examination ; Nitric Oxide Synthase/genetics ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type II ; Prostaglandin-Endoperoxide Synthases/genetics ; Prostaglandin-Endoperoxide Synthases/metabolism ; RNA, Messenger/biosynthesis ; Rats ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Tetrazolium Salts/metabolism ; Time Factors
Czasopismo naukowe
    Wyświetlanie 1-10 z 10

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