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    Wyświetlanie 1-13 z 13
    Tytuł:
    Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma.
    Autorzy:
    Jeon AJ; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Teo YY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Sekar K; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Chong SL; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Wu L; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Chew SC; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Kendarsari RI; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Lai H; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Ling WH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore.
    Kaya NA; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Ramasamy A; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Oguz G; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
    Chung AY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore.
    Chan CY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore.
    Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore.
    Kam JH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore.
    Madhavan K; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.
    Kow A; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.
    Ganpathi IS; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore.
    Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore.
    Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore.
    Loh TJ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore.
    Wan WK; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore.
    Soon GST; Department of Pathology, National University Hospital, Singapore, 119074, Singapore.
    Pang YH; Department of Pathology, National University Hospital, Singapore, 119074, Singapore.
    Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
    Ong DB; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
    Lim J; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
    de Villa VH; Department of Surgery and Center for Liver Health and Transplantation, The Medical City, Pasig City, Metro Manila, Philippines.
    Cruz RDD; Department of Laboratory Medicine and Pathology, The Medical City, Pasig City, Metro Manila, Philippines.
    Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok, Thailand.
    Thammasiri J; Division of Pathology, National Cancer Institute, Bangkok, Thailand.
    Bonney GK; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.
    Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore.
    Tucker-Kellogg G; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
    Foo RSY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
    Chow PKH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore. .; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore. .; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore. .
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    Źródło:
    BMC cancer [BMC Cancer] 2023 Feb 03; Vol. 23 (1), pp. 118. Date of Electronic Publication: 2023 Feb 03.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Carcinoma, Hepatocellular*/genetics
    Carcinoma, Hepatocellular*/pathology
    Liver Neoplasms*/genetics
    Liver Neoplasms*/pathology
    Humans ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Prognosis ; Gene Expression Regulation, Neoplastic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma.
    Autorzy:
    Sieow JL; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
    Penny HL; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Gun SY; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Tan LQ; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Duan K; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Yeong JPS; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Pang A; Department of Haematology-Oncology, National University Cancer Institute, Singapore 119228, Singapore.
    Lim D; Department of Pathology, National University Health System, Singapore 119074, Singapore.
    Toh HC; Department of Oncology, National Cancer Centre, Singapore 169610, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Engleman E; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
    Rotzschke O; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Ng LG; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Chen J; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
    Tan SM; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
    Wong SC; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Jan 01; Vol. 24 (1). Date of Electronic Publication: 2023 Jan 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Pancreatic Neoplasms*/pathology
    Carcinoma, Pancreatic Ductal*/pathology
    Humans ; Animals ; Mice ; Neutrophils/metabolism ; Cell Line, Tumor ; Mice, Knockout ; Carcinogenesis ; Hypoxia-Inducible Factor 1 ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Tumor Microenvironment/genetics ; Pancreatic Neoplasms
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Intraperitoneally Delivered Umbilical Cord Lining Mesenchymal Stromal Cells Improve Survival and Kidney Function in Murine Lupus via Myeloid Pathway Targeting.
    Autorzy:
    Chua AWC; Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore 169856, Singapore.
    Guo D; Department of Clinical Translational Research, Singapore General Hospital, Singapore 169608, Singapore.
    Tan JC; Single-Cell Computational Immunology, Singapore Immunology Network, Singapore 138668, Singapore.
    Lim FTW; Department of Clinical Translational Research, Singapore General Hospital, Singapore 169608, Singapore.
    Ong CT; CellResearch Corporation Pte Ltd., Singapore 048943, Singapore.
    Masilamani J; CellResearch Corporation Pte Ltd., Singapore 048943, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Hwang WYK; Department of Hematology, Singapore General Hospital, Singapore 169856, Singapore.; National Cancer Centre Singapore, Singapore 169610, Singapore.
    Lim IJ; CellResearch Corporation Pte Ltd., Singapore 048943, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
    Chen J; Single-Cell Computational Immunology, Singapore Immunology Network, Singapore 138668, Singapore.
    Phan TT; CellResearch Corporation Pte Ltd., Singapore 048943, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
    Fan X; Department of Clinical Translational Research, Singapore General Hospital, Singapore 169608, Singapore.; SingHealth Duke-NUS Medicine Academic Clinical Programme, Duke-NUS Medical School, Singapore 169857, Singapore.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Dec 26; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 26.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Lupus Nephritis*
    Mesenchymal Stem Cells*/metabolism
    Lupus Erythematosus, Systemic*/therapy
    Female ; Humans ; Animals ; Mice ; Mice, Inbred MRL lpr ; Kidney/metabolism ; Cytokines/therapeutic use ; Immunoglobulin G/therapeutic use ; Umbilical Cord/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Human Umbilical Cord Lining-Derived Epithelial Cells: A Potential Source of Non-Native Epithelial Cells That Accelerate Healing in a Porcine Cutaneous Wound Model.
    Autorzy:
    Kua JEH; Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore.
    Siow CW; Skin Bank Unit, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
    Lim WK; Skin Bank Unit, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
    Masilamani J; CellResearch Corporation Pte. Ltd., 137 Market Street, Grace Global Raffles #08-02, Singapore 048943, Singapore.
    Tjin MS; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
    Yeong J; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, 61 Biopolis, Proteos, Singapore 138673, Singapore.; Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore.
    Phan TT; CellResearch Corporation Pte. Ltd., 137 Market Street, Grace Global Raffles #08-02, Singapore 048943, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge Road, Singapore 119228, Singapore.
    Chua AWC; Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore.; Skin Bank Unit, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.; Musculoskeletal Sciences Academic Clinical Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Aug 10; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 10.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Umbilical Cord*
    Wound Healing*
    Animals ; Epithelial Cells/metabolism ; Humans ; Keratinocytes ; Skin/metabolism ; Swine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Clinicopathological-Associated Regulatory Network of Deregulated circRNAs in Hepatocellular Carcinoma.
    Autorzy:
    Han J; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
    Thurnherr T; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 119077, Singapore.
    Chung AYF; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.
    Goh BKP; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.
    Chow PKH; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School Singapore, Singapore 169547, Singapore.; Department of Surgical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
    Chan CY; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.
    Cheow PC; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.
    Lee SY; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.
    Lim TKH; Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore.
    Chong SS; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
    Ooi LLPJ; Department of Hepato-Pancreato-Biliary & Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School Singapore, Singapore 169547, Singapore.; Department of Surgical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
    Lee CG; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 119077, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School Singapore, Singapore 169547, Singapore.; Division of Cellular & Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre Singapore, Level 6, Lab 5, 11 Hospital Drive, Singapore 169610, Singapore.
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    Źródło:
    Cancers [Cancers (Basel)] 2021 Jun 02; Vol. 13 (11). Date of Electronic Publication: 2021 Jun 02.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Biomarkers for Precision Urothelial Carcinoma Diagnosis: Current Approaches and the Application of Single-Cell Technologies.
    Autorzy:
    Hong M; A. Menarini Biomarkers Singapore Pte Ltd., Singapore 117440, Singapore.
    He G; Department of Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Goh S; Department of Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Low AWX; Department of Urology, Singapore General Hospital, Singapore 169854, Singapore.
    Tay KJ; Department of Urology, Singapore General Hospital, Singapore 169854, Singapore.
    Lim TKH; Department of Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Yeong J; Department of Pathology, Singapore General Hospital, Singapore 169856, Singapore.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore 138673, Singapore.
    Khor LY; Department of Pathology, Singapore General Hospital, Singapore 169856, Singapore.
    Lim TS; A. Menarini Biomarkers Singapore Pte Ltd., Singapore 117440, Singapore.
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    Źródło:
    Cancers [Cancers (Basel)] 2021 Jan 12; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 12.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Partial absence of PD-1 expression by tumor-infiltrating EBV-specific CD8 T cells in EBV-driven lymphoepithelioma-like carcinoma.
    Autorzy:
    Simoni Y; Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle WA USA.; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.; ImmunoScape Pte Ltd Singapore.
    Becht E; Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle WA USA.; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.
    Li S; Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle WA USA.; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.
    Loh CY; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.
    Yeong JPS; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.; Department of Anatomical Pathology Singapore General Hospital Singapore General Hospital Singapore.
    Lim TKH; Department of Anatomical Pathology Singapore General Hospital Singapore General Hospital Singapore.
    Takano A; Department of Anatomical Pathology Singapore General Hospital Singapore General Hospital Singapore.
    Tan DSW; Division of Medical Oncology National Cancer Centre Singapore (NCCS) Singapore.; Agency for Science, Technology and Research (ASTAR) Genome Institute of Singapore (GIS) Singapore.
    Newell EW; Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Seattle WA USA.; Agency for Science, Technology and Research Singapore (ASTAR) Singapore Immunology Network (SIgN) Singapore.; Senior Corresponding Author.
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    Źródło:
    Clinical & translational immunology [Clin Transl Immunology] 2020 Sep 09; Vol. 9 (9), pp. e1175. Date of Electronic Publication: 2020 Sep 09 (Print Publication: 2020).
    Typ publikacji:
    Case Reports
    Raport
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Network of clinically-relevant lncRNAs-mRNAs associated with prognosis of hepatocellular carcinoma patients.
    Autorzy:
    Lim LJ; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
    Jin Y; Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre Singapore, Level 6, Lab 5, 11 Hospital Drive, 169610, Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
    Yang H; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
    Chung AYF; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Goh BKP; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Chow PKH; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Graduate School, Singapore, Singapore.; Department of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Chan CY; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Blanks WK; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; The University of North Carolina, Chapel Hill, USA.
    Cheow PC; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Lee SY; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Lim TKH; Department of Pathology, Singapore General Hospital, Singapore, Singapore.
    Chong SS; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
    Ooi LLPJ; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Graduate School, Singapore, Singapore.; Department of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Lee CG; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. .; Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre Singapore, Level 6, Lab 5, 11 Hospital Drive, 169610, Singapore, Singapore. .; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore. .; Duke-NUS Graduate School, Singapore, Singapore. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jul 07; Vol. 10 (1), pp. 11124. Date of Electronic Publication: 2020 Jul 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carcinoma, Hepatocellular/*genetics
    Liver Neoplasms/*genetics
    RNA, Long Noncoding/*genetics
    RNA, Messenger/*genetics
    RNA, Neoplasm/*genetics
    Carcinoma, Hepatocellular/diagnosis ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/genetics ; Gene Regulatory Networks/drug effects ; Genetic Markers/genetics ; Humans ; Liver Neoplasms/diagnosis ; Prognosis ; Real-Time Polymerase Chain Reaction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    An Optimised Protocol Harnessing Laser Capture Microdissection for Transcriptomic Analysis on Matched Primary and Metastatic Colorectal Tumours.
    Autorzy:
    Ong CJ; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Tan QX; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Lim HJ; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Shannon NB; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Lim WK; Cancer and Stem Cell Biology, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
    Hendrikson J; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Ng WH; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Tan JWS; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Koh KKN; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Wasudevan SD; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Ng CCY; Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Rajasegaran V; Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Singapore, S169856, Singapore.
    Ong CK; Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Kon OL; Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Teh BT; Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Tan GHC; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Chia CS; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Soo KC; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore.
    Teo MCC; Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, S169610, Singapore. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jan 20; Vol. 10 (1), pp. 682. Date of Electronic Publication: 2020 Jan 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Colorectal Neoplasms/*surgery
    Gene Expression Profiling/*methods
    Krukenberg Tumor/*surgery
    Laser Capture Microdissection/*methods
    Ovarian Neoplasms/*surgery
    Colorectal Neoplasms/genetics ; Colorectal Neoplasms/secondary ; Female ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Krukenberg Tumor/genetics ; Ovarian Neoplasms/genetics ; Sequence Analysis, RNA ; Specimen Handling ; Workflow
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A set of molecular markers predicts chemosensitivity to Mitomycin-C following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis.
    Autorzy:
    Shannon NB; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Tan JW; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Tan HL; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Wang W; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Chen Y; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Lim HJ; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Tan QX; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Hendrikson J; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Ng WH; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Loo LY; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Skanthakumar T; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Wasudevan SD; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Kon OL; Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
    Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.
    Tan GHC; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Chia CS; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Soo KC; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.
    Ong CJ; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore. .
    Teo MCC; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jul 22; Vol. 9 (1), pp. 10572. Date of Electronic Publication: 2019 Jul 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibiotics, Antineoplastic/*therapeutic use
    Colorectal Neoplasms/*therapy
    Cytoreduction Surgical Procedures/*methods
    Hyperthermia, Induced/*methods
    Mitomycin/*therapeutic use
    Peritoneal Neoplasms/*secondary
    Adult ; Aged ; Biomarkers, Tumor/analysis ; Colorectal Neoplasms/chemistry ; Colorectal Neoplasms/pathology ; Combined Modality Therapy ; Female ; Humans ; Male ; Middle Aged ; Peritoneal Neoplasms/chemistry ; Peritoneal Neoplasms/therapy ; Proportional Hazards Models ; Survival Analysis ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circulating microRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma.
    Autorzy:
    Jin Y; Division of Cellular & Molecular Research, National Cancer Centre Singapore, Singapore, Singapore.
    Wong YS; Division of Cellular & Molecular Research, National Cancer Centre Singapore, Singapore, Singapore.
    Goh BKP; Department of Hepato-pancreato-biliary & Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Chan CY; Department of Hepato-pancreato-biliary & Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Cheow PC; Department of Hepato-pancreato-biliary & Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Chow PKH; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore.
    Lim TKH; Department of Pathology, Singapore General Hospital, Singapore, Singapore.
    Goh GBB; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
    Krishnamoorthy TL; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
    Kumar R; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore.
    Ng TP; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
    Chong SS; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Laboratory Medicine, National University Hospital, Singapore, Singapore.
    Tan HH; Blood Services Group, Health Sciences Authority, Singapore, Singapore.
    Chung AYF; Department of Hepato-pancreato-biliary & Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Ooi LLPJ; Department of Hepato-pancreato-biliary & Transplant Surgery, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore.
    Chang JPE; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.
    Tan CK; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore. .
    Lee CGL; Division of Cellular & Molecular Research, National Cancer Centre Singapore, Singapore, Singapore. .; Duke-NUS Graduate Medical School, Singapore, Singapore. .; Department of Biochemistry, National University of Singapore, Singapore, Singapore. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jul 18; Vol. 9 (1), pp. 10464. Date of Electronic Publication: 2019 Jul 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Biomarkers, Tumor/*genetics
    Carcinoma, Hepatocellular/*pathology
    Early Detection of Cancer/*methods
    Hepatitis B, Chronic/*complications
    Liver Cirrhosis/*pathology
    MicroRNAs/*genetics
    Biomarkers, Tumor/blood ; Carcinoma, Hepatocellular/blood ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/virology ; Case-Control Studies ; Disease Progression ; Female ; Follow-Up Studies ; Gene Expression Profiling ; Hepatitis B virus/isolation & purification ; Hepatitis B, Chronic/virology ; Humans ; Liver Cirrhosis/blood ; Liver Cirrhosis/genetics ; Liver Cirrhosis/virology ; Liver Neoplasms/blood ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Liver Neoplasms/virology ; Male ; MicroRNAs/blood ; Middle Aged ; Prognosis ; Survival Rate
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Quantification of hepatic steatosis in chronic liver disease using novel automated method of second harmonic generation and two-photon excited fluorescence.
    Autorzy:
    Goh GB; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
    Leow WQ; Department of Pathology, Singapore General Hospital, Singapore, Singapore.
    Liang S; Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
    Wan WK; Department of Pathology, Singapore General Hospital, Singapore, Singapore.
    Lim TKH; Department of Pathology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
    Tan CK; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
    Chang PE; Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore. .; Duke-NUS Medical School, Singapore, Singapore. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Feb 27; Vol. 9 (1), pp. 2975. Date of Electronic Publication: 2019 Feb 27.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Fatty Liver/*metabolism
    Fatty Liver/*pathology
    Microscopy, Fluorescence, Multiphoton/*methods
    Second Harmonic Generation Microscopy/*methods
    Algorithms ; Automation, Laboratory/methods ; Fatty Liver/diagnosis ; Fluorescence ; Humans ; Liver/pathology ; Liver Cirrhosis/pathology ; Liver Diseases/pathology ; Photons ; Reproducibility of Results
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prognostic significance of KIT exon 11 deletion mutation in intermediate-risk gastrointestinal stromal tumor.
    Autorzy:
    Quek R; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore.
    Farid M; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
    Kanjanapan Y; Department of Medical Oncology, The Canberra Hospital, Garran, Australia.
    Lim C; Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore.
    Tan IB; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore.; Genome Institute of Singapore, Singapore.
    Kesavan S; Department of Pathology, Singapore General Hospital, Singapore.
    Lim TKH; Duke-NUS Graduate Medical School, Singapore.; Department of Pathology, Singapore General Hospital, Singapore.; School of Biological Sciences, Nanyang Technological University Singapore, Singapore.
    Oon LL; Department of Pathology, Singapore General Hospital, Singapore.
    Goh BK; Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.
    Chan WH; Department of Surgery, Singapore General Hospital, Singapore.
    Teo M; Division of Surgical Oncology, National Cancer Centre Singapore, Singapore.
    Chung AY; Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.
    Ong HS; Department of Upper GI and Bariatric Surgery, Singapore General Hospital, Singapore.
    Wong WK; Department of Upper GI and Bariatric Surgery, Singapore General Hospital, Singapore.
    Tan P; Genome Institute of Singapore, Singapore.; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore.; Center for Translational Medicine, Cancer Science Institute of Singapore, National University of Singapore, Singapore.
    Yip D; Department of Medical Oncology, The Canberra Hospital, Garran, Australia.; ANU Medical School, Australian National University, Acton, Canberra, Australia.
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    Źródło:
    Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2017 Jun; Vol. 13 (3), pp. 115-124. Date of Electronic Publication: 2016 Oct 17.
    Typ publikacji:
    Journal Article; Multicenter Study
    MeSH Terms:
    Exons*
    Sequence Deletion*
    Gastrointestinal Stromal Tumors/*genetics
    Proto-Oncogene Proteins c-kit/*genetics
    Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-13 z 13

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