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    Wyświetlanie 1-9 z 9
    Tytuł:
    Inflammasome Coordinates Senescent Chronic Wound Induced by Thalassophryne nattereri Venom.
    Autorzy:
    Lima C; Immunoregulation Unit of the Laboratory of Applied Toxinology (CETICs/FAPESP), Butantan Institute, São Paulo 05503-009, Brazil.
    Andrade-Barros AI; Immunoregulation Unit of the Laboratory of Applied Toxinology (CETICs/FAPESP), Butantan Institute, São Paulo 05503-009, Brazil.
    Carvalho FF; Immunoregulation Unit of the Laboratory of Applied Toxinology (CETICs/FAPESP), Butantan Institute, São Paulo 05503-009, Brazil.
    Falcão MAP; Immunoregulation Unit of the Laboratory of Applied Toxinology (CETICs/FAPESP), Butantan Institute, São Paulo 05503-009, Brazil.
    Lopes-Ferreira M; Immunoregulation Unit of the Laboratory of Applied Toxinology (CETICs/FAPESP), Butantan Institute, São Paulo 05503-009, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 May 08; Vol. 24 (9). Date of Electronic Publication: 2023 May 08.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Venoms*
    Fish Venoms*/pharmacology
    Mice ; Animals ; Inflammasomes ; Inflammation/chemically induced ; Neutrophils ; Caspase 1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effective Pre-Clinical Treatment of Fish Envenoming with Polyclonal Antiserum.
    Autorzy:
    Lopes Ferreira M; Immunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Falcão MAP; Immunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Bruni FM; Immunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Haddad V Jr; Faculdade de Medicina, Universidade Estadual Paulista, Botucatu 18618-689, Brazil.
    Marques EE; Environmental Sciences, Campus of Palmas, Federal University of Tocantins, Palmas 77001-090, Brazil.
    Seibert CS; Environmental Sciences, Campus of Palmas, Federal University of Tocantins, Palmas 77001-090, Brazil.
    Lima C; Immunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 May 06; Vol. 24 (9). Date of Electronic Publication: 2023 May 06.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Fish Venoms*/toxicity
    Batrachoidiformes*
    Perciformes*
    Catfishes*
    Mice ; Animals ; Immune Sera
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Natterin-like depletion by CRISPR/Cas9 impairs zebrafish (Danio rerio) embryonic development.
    Autorzy:
    Seni-Silva AC; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.; Post-Graduation Program of Toxinology, Butantan Institute, São Paulo, SP, Brazil.
    Maleski ALA; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.; Post-Graduation Program of Toxinology, Butantan Institute, São Paulo, SP, Brazil.
    Souza MM; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.
    Falcao MAP; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.
    Disner GR; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.
    Lopes-Ferreira M; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil.
    Lima C; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500, Butantan, São Paulo, 05503-009, Brazil. carla.lima@butantan.gov.br.
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    Źródło:
    BMC genomics [BMC Genomics] 2022 Feb 12; Vol. 23 (1), pp. 123. Date of Electronic Publication: 2022 Feb 12.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Fish Venoms*
    Zebrafish*/genetics
    Animals ; CRISPR-Cas Systems ; Embryonic Development/genetics ; Pore Forming Cytotoxic Proteins ; Zebrafish Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Molecular Characterization and Functional Analysis of the Nattectin-like Toxin from the Venomous Fish Thalassophryne maculosa .
    Autorzy:
    Lopes-Ferreira M; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
    Sosa-Rosales I; Escuela de Ciências Aplicadas del Mar, Universidad de Oriente, Boca de Rio 6304, Venezuela.
    Silva Junior PI; Protein Chemistry Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
    Conceicao K; Peptide Biochemistry Laboratory, UNIFESP, Sao Jose dos Campos 12247-014, Brazil.
    Maleski ALA; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.; Post-Graduation Program of Toxinology, Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
    Balan-Lima L; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
    Disner GR; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
    Lima C; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, Sao Paulo 05503-009, Brazil.
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    Źródło:
    Toxins [Toxins (Basel)] 2021 Dec 21; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 21.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Batrachoidiformes*
    Fish Venoms/*chemistry
    Lectins, C-Type/*chemistry
    Marine Toxins/*chemistry
    Amino Acid Sequence ; Animals ; Fish Venoms/pharmacology ; Marine Toxins/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Natterin Proteins Diversity: A Review on Phylogeny, Structure, and Immune Function.
    Autorzy:
    Lima C; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
    Disner GR; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
    Falcão MAP; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
    Seni-Silva AC; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.; Post-Graduation Program of Toxinology, Butantan Institute, São Paulo 05503-900, Brazil.
    Maleski ALA; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.; Post-Graduation Program of Toxinology, Butantan Institute, São Paulo 05503-900, Brazil.
    Souza MM; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
    Reis Tonello MC; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
    Lopes-Ferreira M; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brasil Avenue, 1500 Butantan, São Paulo 05503-900, Brazil.
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    Źródło:
    Toxins [Toxins (Basel)] 2021 Jul 31; Vol. 13 (8). Date of Electronic Publication: 2021 Jul 31.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Fish Venoms*/chemistry
    Fish Venoms*/genetics
    Fish Venoms*/immunology
    Pore Forming Cytotoxic Proteins*/chemistry
    Pore Forming Cytotoxic Proteins*/genetics
    Pore Forming Cytotoxic Proteins*/immunology
    Animals ; Molecular Structure ; Phylogeny
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    In Silico Target Prediction of Overexpressed microRNAs from LPS-Challenged Zebrafish ( Danio rerio ) Treated with the Novel Anti-Inflammatory Peptide Tn P.
    Autorzy:
    Disner GR; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICS/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Falcão MAP; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICS/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Lima C; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICS/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Lopes-Ferreira M; Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICS/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
    Pokaż więcej
    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Jul 01; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Anti-Inflammatory Agents/*pharmacology
    Fish Venoms/*pharmacology
    Gene Expression/*drug effects
    MicroRNAs/*genetics
    Peptides/*pharmacology
    Animals ; Computational Biology/methods ; Computer Simulation ; DNA-Binding Proteins/metabolism ; Gene Ontology ; Immunity, Innate/genetics ; Lipopolysaccharides/pharmacology ; MicroRNAs/biosynthesis ; MicroRNAs/metabolism ; Transcription Factors/metabolism ; Transcriptome ; Zebrafish
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
    Autorzy:
    Komegae EN; Immunoregulation Unit, Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, Brazil.
    Souza TA; Immunoregulation Unit, Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, Brazil.
    Grund LZ; Immunoregulation Unit, Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, Brazil.
    Lima C; Immunoregulation Unit, Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, Brazil.
    Lopes-Ferreira M; Immunoregulation Unit, Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, Brazil.
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    Źródło:
    PloS one [PLoS One] 2017 Feb 24; Vol. 12 (2), pp. e0171796. Date of Electronic Publication: 2017 Feb 24 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Encephalomyelitis, Autoimmune, Experimental/*drug therapy
    Fish Venoms/*chemistry
    Immunologic Factors/*pharmacology
    Peptides/*pharmacology
    Spinal Cord/*drug effects
    T-Lymphocytes, Regulatory/*drug effects
    Amino Acid Sequence ; Animals ; Antigens, Differentiation/genetics ; Antigens, Differentiation/immunology ; Brazil ; Cuprizone ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/chemically induced ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Female ; Gene Expression Regulation ; Immunologic Factors/isolation & purification ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukin-10/genetics ; Interleukin-10/immunology ; Interleukin-17/genetics ; Interleukin-17/immunology ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/pathology ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/immunology ; Mice ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/immunology ; Multiple Sclerosis/pathology ; Peptides/isolation & purification ; Perciformes/metabolism ; Spinal Cord/immunology ; Spinal Cord/pathology ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/pathology ; Th1 Cells/drug effects ; Th1 Cells/immunology ; Th1 Cells/pathology ; Th17 Cells/drug effects ; Th17 Cells/immunology ; Th17 Cells/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation.
    Autorzy:
    Pareja-Santos A; Special Laboratory of Applied Toxinology (CAT/CEPID), Butantan Institute, Butantan, Sao Paulo, Brazil.
    Saraiva TC
    Costa EP
    Santos MF
    Zorn TT
    Souza VM
    Lopes-Ferreira M
    Lima C
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    Źródło:
    International journal of experimental pathology [Int J Exp Pathol] 2009 Feb; Vol. 90 (1), pp. 34-43.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Batrachoidiformes/*metabolism
    Extracellular Matrix/*drug effects
    Fish Venoms/*toxicity
    Inflammation/*chemically induced
    Animals ; Cells, Cultured ; Chemotaxis, Leukocyte/drug effects ; Collagen/metabolism ; Cytoskeleton/drug effects ; Cytoskeleton/pathology ; Extracellular Matrix/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Male ; Matrix Metalloproteinases/biosynthesis ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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