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Tytuł:
The implication of LPS/TLR4 and FXR receptors in hepatoprotective efficacy of indole-3-acetic acid and chenodeoxycholic acid.
Autorzy:
Aljarboa AS; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Electronic address: .
Alhusaini AM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Electronic address: .
Sarawi WS; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Electronic address: .
Mohammed R; Department of Histology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia. Electronic address: .
Ali RA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Electronic address: .
Hasan IH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Dec 01; Vol. 334, pp. 122182. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/pharmacology
Chemical and Drug Induced Liver Injury, Chronic*/metabolism
Rats ; Animals ; Chenodeoxycholic Acid/pharmacology ; Chenodeoxycholic Acid/metabolism ; Toll-Like Receptor 4/metabolism ; Liver/metabolism ; Glutathione/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Transcriptomic analysis reveals that RasGEF1b deletion alters basal and LPS-induced expression of genes involved in chemotaxis and cytokine responses in macrophages.
Autorzy:
Fernandes HB; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.
de Oliveira IM; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.; Faculdade de Medicina de Ribeirão Preto, Av. Bandeirantes, 3900 - Campus da USP, Ribeirão Preto, SP, 14049-900, Brazil.
Postler TS; Department of Microbiology & Immunology, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY, USA.; Design and Development Laboratory, International AIDS Vaccine Initiative, Brooklyn, NY, USA.
Lima SQ; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.
Santos CAC; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.; Instituto Federal de Educação, Ciência e Tecnologia de Rondônia (IFRO), Guajará-Mirim, RO, Brazil.
Oliveira MS; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.
Leão FB; Department of Microbiology & Immunology, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Ghosh S; Department of Microbiology & Immunology, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Souza MC; Faculdade de Medicina de Ribeirão Preto, Av. Bandeirantes, 3900 - Campus da USP, Ribeirão Preto, SP, 14049-900, Brazil.
Andrade W; Faculdade de Medicina de Ribeirão Preto, Av. Bandeirantes, 3900 - Campus da USP, Ribeirão Preto, SP, 14049-900, Brazil.
Silva AM; Laboratory of Inflammatory Genes, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 10; Vol. 13 (1), pp. 19614. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytokines*/genetics
Cytokines*/metabolism
Lipopolysaccharides*/pharmacology
Lipopolysaccharides*/metabolism
Animals ; Mice ; Chemotaxis ; Macrophages/metabolism ; Transcriptome
Czasopismo naukowe
Szczegóły
Tytuł:
Daeshiho-tang attenuates inflammatory response and oxidative stress in LPS-stimulated macrophages by regulating TLR4/MyD88, NF-κB, MAPK, and Nrf2/HO-1 pathways.
Autorzy:
Oh YJ; KM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Jin SE; KM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Shin HK; KM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Ha H; KM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 02; Vol. 13 (1), pp. 18891. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/metabolism
Lipopolysaccharides*/toxicity
Lipopolysaccharides*/metabolism
Animals ; Mice ; Myeloid Differentiation Factor 88/metabolism ; NF-E2-Related Factor 2/metabolism ; Toll-Like Receptor 4/metabolism ; Macrophages/metabolism ; Anti-Inflammatory Agents/therapeutic use ; RAW 264.7 Cells ; Oxidative Stress ; Nitric Oxide Synthase Type II/metabolism ; Cyclooxygenase 2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LPS induces SGPP2 to participate metabolic reprogramming in endothelial cells.
Autorzy:
Yi X; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chang ML; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhou ZD; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi L; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan H; Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qi J; Department of Orthopedics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi L; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .
Huan JN; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .
Huang XQ; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xqhuang_.
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2023 Nov 01; Vol. 208, pp. 780-793. Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biochemical Phenomena*
Lipopolysaccharides*/pharmacology
Lipopolysaccharides*/metabolism
Animals ; Humans ; Human Umbilical Vein Endothelial Cells ; Inflammation/genetics ; Inflammation/metabolism ; Phosphoric Monoester Hydrolases/metabolism ; Zebrafish/genetics ; Zebrafish/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Exploring the effects of embryonic and neonatal exposure to lipopolysaccharides on oligodendrocyte differentiation in the rat hippocampus and the protective effect of alpha-glycosyl isoquercitrin.
Autorzy:
Okano H; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Ojiro R; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Zou X; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Tang Q; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Ozawa S; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Koyanagi M; Global Scientific and Regulatory Affairs, San-Ei Gen F.F.I. Inc., 1-1-11 Sanwa-cho, Toyonaka, Osaka 561-8588, Japan.
Maronpot RR; Maronpot Consulting, LLC, 1612 Medfield Road, Raleigh, NC 27607, USA.
Yoshida T; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Shibutani M; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan. Electronic address: .
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Źródło:
Journal of chemical neuroanatomy [J Chem Neuroanat] 2023 Nov; Vol. 133, pp. 102336. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipopolysaccharides*/pharmacology
Hippocampus*
Rats ; Animals ; Male ; Rats, Sprague-Dawley ; Antioxidants/pharmacology ; Cell Differentiation/physiology ; Oligodendroglia ; Body Weight ; 2',3'-Cyclic-Nucleotide Phosphodiesterases/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells.
Autorzy:
Okojie AK; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA. .; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA. .
Uweru JO; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Coburn MA; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Li S; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.
Cao-Dao VD; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Eyo UB; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA. .; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Oct 21; Vol. 20 (1), pp. 242. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Microglia*/metabolism
Lipopolysaccharides*/toxicity
Lipopolysaccharides*/metabolism
Mice ; Animals ; Macrophages ; Aminopyridines/pharmacology ; Receptors, Colony-Stimulating Factor/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years.
Autorzy:
Read JF; Asthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, United States.; Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
Serralha M; Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
Armitage JD; Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.; School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Iqbal MM; Genomics WA, Joint Initiative of Telethon Kids Institute, Harry Perkins Institute of Medical Research and The University of Western Australia, Nedlands, WA, Australia.
Cruickshank MN; School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Saxena A; Genomics WA, Joint Initiative of Telethon Kids Institute, Harry Perkins Institute of Medical Research and The University of Western Australia, Nedlands, WA, Australia.
Strickland DH; Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.; UWA Centre for Child Health Research, The University of Western Australia, Nedlands, WA, Australia.
Waithman J; School of Biomedical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.
Holt PG; Telethon Kids Institute, The University of Western Australia, Perth, WA, Australia.; UWA Centre for Child Health Research, The University of Western Australia, Nedlands, WA, Australia.
Bosco A; Asthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, United States.; Department of Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Oct 17; Vol. 14, pp. 1275937. Date of Electronic Publication: 2023 Oct 17 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipopolysaccharides*/pharmacology
Lipopolysaccharides*/metabolism
Transcriptome*
Infant, Newborn ; Humans ; Monocytes ; Signal Transduction ; Gene Expression Regulation ; Poly I-C/pharmacology ; Poly I-C/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Immune evasion through Toll-like receptor 4: The role of the core oligosaccharides from α2-Proteobacteria atypical lipopolysaccharides.
Autorzy:
Matamoros-Recio A; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas 'Margarita Salas', CSIC, C/ Ramiro de Maeztu, 9, 28040 Madrid, Spain. Electronic address: .
Merino J; Centro de Biología Molecular 'Severo Ochoa', CSIC-Universidad Autónoma de Madrid, C/ Nicolás Cabrera, 1, 28049 Madrid, Spain.
Gallego-Jiménez A; Centro de Biología Molecular 'Severo Ochoa', CSIC-Universidad Autónoma de Madrid, C/ Nicolás Cabrera, 1, 28049 Madrid, Spain.
Conde-Alvarez R; Dpto. de Microbiología y Parasitología, Instituto de Salud Tropical (ISTUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Universidad de Navarra, Campus Universitario, 31009 Pamplona, Spain.
Fresno M; Centro de Biología Molecular 'Severo Ochoa', CSIC-Universidad Autónoma de Madrid, C/ Nicolás Cabrera, 1, 28049 Madrid, Spain.
Martín-Santamaría S; Department of Structural and Chemical Biology, Centro de Investigaciones Biológicas 'Margarita Salas', CSIC, C/ Ramiro de Maeztu, 9, 28040 Madrid, Spain. Electronic address: .
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Źródło:
Carbohydrate polymers [Carbohydr Polym] 2023 Oct 15; Vol. 318, pp. 121094. Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/chemistry
Bacterial Infections*
Humans ; Toll-Like Receptor 4 ; Lipid A/chemistry ; Proteobacteria ; Immune Evasion ; Bacteria ; Oligosaccharides
Czasopismo naukowe
Szczegóły
Tytuł:
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction.
Autorzy:
Sabogal-Guáqueta AM; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.
Marmolejo-Garza A; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences of Cells & Systems, section Molecular Neurobiology, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Trombetta-Lima M; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences of Cells & Systems, section Molecular Neurobiology, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Oun A; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.
Hunneman J; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.
Chen T; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands.
Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.; Neuroscience Center, Helsinki Institute for Life Science, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.
Lehtonen S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.
Kortholt A; Department of Cell Biochemistry, University of Groningen, Groningen, The Netherlands.; YETEM-Innovative Technologies Application and Research Centre Suleyman Demirel University, Isparta, Turkey.
Wolters JC; Laboratory of Pediatrics, Section Systems Medicine of Metabolism and Signaling, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Bakker BM; Laboratory of Pediatrics, Section Systems Medicine of Metabolism and Signaling, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Eggen BJL; Department of Biomedical Sciences of Cells & Systems, section Molecular Neurobiology, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Boddeke E; Department of Biomedical Sciences of Cells & Systems, section Molecular Neurobiology, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Dolga A; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 13; Vol. 14 (1), pp. 6454. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microglia*/metabolism
Lipopolysaccharides*/pharmacology
Lipopolysaccharides*/metabolism
Animals ; Mice ; Humans ; Proteomics ; Oxidative Phosphorylation ; Glycolysis
Czasopismo naukowe
Szczegóły
Tytuł:
Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway.
Autorzy:
Ren X; School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, No. 37, Shi-er-qiao Road, Jinniu District, 610075, 610075, Chengdu, Chengdu, Sichuan, China.; Department of Integrative Medicine, Xinqiao Hospital, Army Medical University, Chongqing, China.
Dai Y; Department of Integrative Medicine, Xinqiao Hospital, Army Medical University, Chongqing, China.
Shan M; Department of Integrative Medicine, Xinqiao Hospital, Army Medical University, Chongqing, China.
Zheng J; Department of Integrative Medicine, Xinqiao Hospital, Army Medical University, Chongqing, China.
Zhang Z; School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, No. 37, Shi-er-qiao Road, Jinniu District, 610075, 610075, Chengdu, Chengdu, Sichuan, China.
Shen T; School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, No. 37, Shi-er-qiao Road, Jinniu District, 610075, 610075, Chengdu, Chengdu, Sichuan, China. .
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Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Oct 10; Vol. 23 (1), pp. 358. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/pharmacology
Proto-Oncogene Proteins c-akt*/metabolism
Rats ; Animals ; Insulin Secretion ; Sirolimus ; Glucose/metabolism ; Polysaccharides/pharmacology ; TOR Serine-Threonine Kinases/metabolism ; Glucose Transport Proteins, Facilitative/metabolism ; Mammals/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Xanthorrhizol inhibits mitochondrial damage, oxidative stress and inflammation in LPS-induced MLE-12 cells by regulating MAPK pathway.
Autorzy:
Sun W; Department of Emergency Medicine, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China.
Liu M; Department of Infectious Diseases, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China. Electronic address: Liuming_.
Li Y; Department of Emergency Medicine, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China.
Hu X; Department of Emergency Medicine, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China.
Chen G; Department of Emergency Medicine, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China.
Zhang F; Department of Emergency Medicine, Xining No.1 People's Hospital, Xining 810000, Qinghai, PR China.
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Źródło:
Tissue & cell [Tissue Cell] 2023 Oct; Vol. 84, pp. 102170. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/toxicity
Lipopolysaccharides*/metabolism
Lung*
Animals ; Mice ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Oxidative Stress
Czasopismo naukowe
Szczegóły
Tytuł:
Radiographic and histopathological study of gastrointestinal dysmotility in lipopolysaccharide-induced sepsis in the rat.
Autorzy:
Castro M; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Universidad de Zaragoza, Zaragoza, Spain.; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.; Instituto Agroalimentario de Aragón (IA2), Universidad de Zaragoza-CITA, Zaragoza, Spain.
Valero MS; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Universidad de Zaragoza, Zaragoza, Spain.; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.; Instituto Agroalimentario de Aragón (IA2), Universidad de Zaragoza-CITA, Zaragoza, Spain.
López-Tofiño Y; Área de Farmacología y Nutrición, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.; High-Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), Alcorcón, Spain.
López-Gómez L; High-Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), Alcorcón, Spain.; Área de Histología Humana y Anatomía Patológica, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.
Girón R; Área de Farmacología y Nutrición, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.; High-Performance Research Group in Experimental Pharmacology (PHARMAKOM-URJC), Alcorcón, Spain.; Unidad Asociada I+D+i del Instituto de Química Médica (IQM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
Martín-Fontelles MI; Área de Farmacología y Nutrición, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.; Unidad Asociada I+D+i del Instituto de Química Médica (IQM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.; Grupo de Trabajo de Ciencias Básicas en Dolor y Analgesia de la Sociedad Española del Dolor, Madrid, Spain.
Uranga JA; High-Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), Alcorcón, Spain.; Área de Histología Humana y Anatomía Patológica, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.
Abalo R; Área de Farmacología y Nutrición, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, Spain.; High-Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), Alcorcón, Spain.; Unidad Asociada I+D+i del Instituto de Química Médica (IQM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.; Grupo de Trabajo de Ciencias Básicas en Dolor y Analgesia de la Sociedad Española del Dolor, Madrid, Spain.; Grupo de Trabajo de Cannabinoides de la Sociedad Española del Dolor, Madrid, Spain.
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Źródło:
Neurogastroenterology and motility [Neurogastroenterol Motil] 2023 Oct; Vol. 35 (10), pp. e14639. Date of Electronic Publication: 2023 Jul 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipopolysaccharides*/toxicity
Sepsis*/complications
Rats ; Male ; Animals ; Escherichia coli ; Cytokines/metabolism ; Ileum/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Structural characterization and anti-inflammatory effects of Enteromorpha prolifera polysaccharide-Fe/Zn complexes.
Autorzy:
Feng Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Wu Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Duan R; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Wang P; Qingdao Seawin Biotech Group Co., LTD, Qingdao 266071, China.
Zhong X; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Wu X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences; Changsha, Hunan 410125, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 6), pp. 127166. Date of Electronic Publication: 2023 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/pharmacology
Zinc*/chemistry
Chelating Agents/chemistry ; Iron/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Exopolysaccharide produced by Lactiplantibacillus plantarum Y12 exhibits inhibitory effect on the Shigella flexneri genes expression related to biofilm formation.
Autorzy:
Song Y; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China.
Sun M; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China.
Mu G; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Dalian Probiotics Function Research Key Laboratory, Dalian Polytechnic University, Dalian 116034, PR China. Electronic address: .
Tuo Y; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 5), pp. 127048. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Shigella flexneri*
Lipopolysaccharides*/pharmacology
Humans ; Biofilms ; Gene Expression Profiling
Czasopismo naukowe
Szczegóły
Tytuł:
Alleviative effect of poly-β-hydroxybutyrate on lipopolysaccharide-induced oxidative stress, inflammation and cell apoptosis in Cyprinus carpio.
Autorzy:
Li L; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, China.
Wei XF; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Yang ZY; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Zhu R; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Li DL; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Shang GJ; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Wang HT; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Meng ST; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Wang YT; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Liu SY; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China.
Wu LF; College of Animal Science and Technology/College of Animal Medicine, Jilin Agricultural University, Changchun, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 2), pp. 126784. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/toxicity
Carps*
Animals ; Kelch-Like ECH-Associated Protein 1 ; NLR Family, Pyrin Domain-Containing 3 Protein ; NF-E2-Related Factor 2 ; Inflammation/chemically induced ; Inflammation/drug therapy ; Oxidative Stress ; Inflammasomes ; Apoptosis ; RNA, Messenger ; Superoxide Dismutase/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264.7 macrophages.
Autorzy:
Zhao Q; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan, China.
Zheng W; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan, China.
Yuan Z; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan, China.
Wang X; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan, China.
Huang A; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan, China. Electronic address: .
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Źródło:
Food chemistry [Food Chem] 2023 Dec 15; Vol. 429, pp. 136804. Date of Electronic Publication: 2023 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/pharmacology
Buffaloes*/metabolism
Animals ; Mice ; Whey Proteins/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-6/metabolism ; NF-kappa B/metabolism ; Protein Hydrolysates/metabolism ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Macrophages ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/metabolism ; Cytokines/metabolism ; RAW 264.7 Cells
Czasopismo naukowe
Szczegóły
Tytuł:
Protective effect of hydrangenol on lipopolysaccharide-induced endotoxemia by suppressing intestinal inflammation.
Autorzy:
Jang SY; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Kim SY; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea; Department of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea; Neurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Song HA; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Kim H; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Chung KS; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Lee JK; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea; Department of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea; Neurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Lee KT; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea; Department of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea; Neurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2023 Dec; Vol. 125 (Pt A), pp. 111083. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*
Endotoxemia*/chemically induced
Endotoxemia*/drug therapy
Animals ; Mice ; Inflammation/chemically induced ; Inflammation/drug therapy ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Interleukin-6/metabolism ; RNA, Messenger
Czasopismo naukowe
Szczegóły
Tytuł:
Development of an In Vitro Model for Inflammation Mediated Renal Toxicity Using 3D Renal Tubules and Co-Cultured Human Immune Cells.
Autorzy:
Kyun ML; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Park T; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Jung H; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Kim I; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Kwon JI; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Jeong SY; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Choi M; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Park D; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.
Lee YB; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea. .
Moon KS; Department of Advanced Toxicology Research, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea. .
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Źródło:
Tissue engineering and regenerative medicine [Tissue Eng Regen Med] 2023 Dec; Vol. 20 (7), pp. 1173-1190. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:
Journal Article
MeSH Terms:
Leukocytes, Mononuclear*
Lipopolysaccharides*
Humans ; Coculture Techniques ; Cell Line ; Inflammation
Czasopismo naukowe
Szczegóły
Tytuł:
Interaction between mitochondrial homeostasis and barrier function in lipopolysaccharide-induced endothelial cell injury.
Autorzy:
Zhu W; Department of Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, China.
Liu X; Department of Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, China.
Luo L; Department of Hematology, Binzhou Medical University Hospital, Binzhou, China.
Huang X; Department of Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, China.
Wang X; Department of Intensive Care Unit, Binzhou Medical University Hospital, Binzhou, China.
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Źródło:
International journal of experimental pathology [Int J Exp Pathol] 2023 Dec; Vol. 104 (6), pp. 272-282. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/pharmacology
Endothelial Cells*/metabolism
Occludin/metabolism ; Occludin/pharmacology ; Tight Junctions/metabolism ; Oligomycins/pharmacology ; Oligomycins/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Microglia trigger the structural plasticity of GABAergic neurons in the hippocampal CA1 region of a lipopolysaccharide-induced neuroinflammation model.
Autorzy:
Chen J; School of Mental Health, Bengbu Medical College, Bengbu 233030, China.
Wang T; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou 310058, China.
Zhou Y; School of Mental Health, Bengbu Medical College, Bengbu 233030, China.
Hong Y; School of Mental Health, Bengbu Medical College, Bengbu 233030, China.
Zhang S; School of Clinical Medicine, Bengbu Medical College, Bengbu 233030, China.
Zhou Z; School of Nursing, Bengbu Medical College, Bengbu 233030, China.
Jiang A; School of Mental Health, Bengbu Medical College, Bengbu 233030, China.
Liu D; Department of Ophthalmology of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, 1369 West Wenyi Road, Hangzhou 311121, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou 310058, China. Electronic address: .
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Źródło:
Experimental neurology [Exp Neurol] 2023 Dec; Vol. 370, pp. 114565. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CA1 Region, Hippocampal*
Lipopolysaccharides*/toxicity
Mice ; Animals ; Microglia ; Neuroinflammatory Diseases ; GABAergic Neurons ; Synapses/physiology ; Inflammation/chemically induced ; Hippocampus
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 78950

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