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Wyszukujesz frazę ""Lipoproteins, LDL"" wg kryterium: Temat


Tytuł :
Serum gamma-glutamyltransferase, oxidized LDL and mortality in the elderly.
Autorzy :
Spoto B; National Council of Research, Institute of Clinical Physiology (CNR-IFC), Ospedali Riuniti c/o EUROLINE di Barillà, Via Vallone Petrara 55-57, 89124, Reggio Calabria, Italy. .
D'Arrigo G; National Council of Research, Institute of Clinical Physiology (CNR-IFC), Ospedali Riuniti c/o EUROLINE di Barillà, Via Vallone Petrara 55-57, 89124, Reggio Calabria, Italy.
Tripepi G; National Council of Research, Institute of Clinical Physiology (CNR-IFC), Ospedali Riuniti c/o EUROLINE di Barillà, Via Vallone Petrara 55-57, 89124, Reggio Calabria, Italy.
Bolignano D; National Council of Research, Institute of Clinical Physiology (CNR-IFC), Ospedali Riuniti c/o EUROLINE di Barillà, Via Vallone Petrara 55-57, 89124, Reggio Calabria, Italy.
Zoccali C; National Council of Research, Institute of Clinical Physiology (CNR-IFC), Ospedali Riuniti c/o EUROLINE di Barillà, Via Vallone Petrara 55-57, 89124, Reggio Calabria, Italy.
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Źródło :
Aging clinical and experimental research [Aging Clin Exp Res] 2021 May; Vol. 33 (5), pp. 1393-1397. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Lipoproteins, LDL*
gamma-Glutamyltransferase*
Aged ; Biomarkers ; Humans ; Middle Aged ; Proportional Hazards Models ; Risk Factors
Czasopismo naukowe
Tytuł :
Low-density lipoprotein from active SLE patients is more atherogenic to endothelial cells than low-density lipoprotein from the same patients during remission.
Autorzy :
Rodríguez-Calvo R; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Reus, Spain.
Guardiola M; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Reus, Spain.
Oliva I; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Reus, Spain.
Arrando H; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.
Arranz I; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.
Ferré A; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.
Pellicer P; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.
Parra S; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Unitat de Malalties Autoinmunes, Medicina Interna, Hospital Universitari Sant Joan de Reus, Universitat Rovira i Virgili, Reus, Spain.
Ribalta J; Unitat de Recerca en Lípids i Arteriosclerosi, Departament de Medicina i Cirurgia, Universitat Rovira i Virgili, Reus, Spain.; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Reus, Spain.
Castro A; Institut d'Investigació Sanitària Pere Virgili, Reus, Spain.; Unitat de Malalties Autoinmunes, Medicina Interna, Hospital Universitari Sant Joan de Reus, Universitat Rovira i Virgili, Reus, Spain.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Feb 01; Vol. 60 (2), pp. 866-871.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipoproteins, LDL*/blood
Lipoproteins, LDL*/metabolism
Lupus Erythematosus, Systemic*/blood
Lupus Erythematosus, Systemic*/metabolism
Atherosclerosis/*metabolism
Chemokine CCL2/*metabolism
Matrix Metalloproteinase 2/*metabolism
Vascular Cell Adhesion Molecule-1/*metabolism
Aorta/pathology ; Cell Migration Assays/methods ; Cells, Cultured ; Correlation of Data ; Disease Progression ; Endothelial Cells/metabolism ; Female ; Heart Disease Risk Factors ; Humans ; Patient Acuity
Czasopismo naukowe
Tytuł :
[Adsorption behavior of low density lipoprotein on titanium surface].
Autorzy :
Xu LN; Department of Stomatology, Zhongshan Hospital Affiliated to Fudan University. Shanghai 200032, China. E-mail:.
Yu YJ
Sun J
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Źródło :
Shanghai kou qiang yi xue = Shanghai journal of stomatology [Shanghai Kou Qiang Yi Xue] 2021 Feb; Vol. 30 (1), pp. 50-54.
Typ publikacji :
Journal Article
MeSH Terms :
Lipoproteins, LDL*
Titanium*
Adsorption ; Microscopy, Electron, Scanning ; Surface Properties
Czasopismo naukowe
Tytuł :
Genome-scale CRISPR screening for modifiers of cellular LDL uptake.
Autorzy :
Emmer BT; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
Sherman EJ; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Chemical Biology Program, University of Michigan, Ann Arbor, Michigan, United States of America.
Lascuna PJ; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
Graham SE; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Willer CJ; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
Ginsburg D; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, United States of America.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2021 Jan 29; Vol. 17 (1), pp. e1009285. Date of Electronic Publication: 2021 Jan 29 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*genetics
Cholesterol/*genetics
Lipoproteins, LDL/*genetics
Receptors, LDL/*genetics
Atherosclerosis/pathology ; CRISPR-Cas Systems/genetics ; Cholesterol/metabolism ; Endocytosis/genetics ; Gene Expression Regulation/genetics ; Genome, Human/genetics ; Hep G2 Cells ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Humans ; Hypercholesterolemia/genetics ; Hypercholesterolemia/pathology ; Lipoproteins, LDL/metabolism ; RNA, Guide/genetics
Czasopismo naukowe
Tytuł :
A Salt Stimulus-Responsive Nanohydrogel for Controlled Fishing Low-Density Lipoprotein with Superior Adsorption Capacity.
Autorzy :
Cao JF; Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Xu W; Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Zhang YY; Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Shu Y; Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Wang JH; Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jan 27; Vol. 13 (3), pp. 4583-4592. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Chondroitin Sulfates/*chemistry
Hydrogels/*chemistry
Lipoproteins, LDL/*isolation & purification
Nanogels/*chemistry
Silicon Dioxide/*chemistry
Adsorption ; Animals ; Cattle ; Electrophoresis, Polyacrylamide Gel ; Humans ; Lipoproteins, LDL/blood ; Magnesium Chloride/chemistry
Czasopismo naukowe
Tytuł :
The effect of type 2 diabetes on CD36 expression and the uptake of oxLDL: Diabetes affects CD36 and oxLDL uptake.
Autorzy :
Kanoke A; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Nishijima Y; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Ljungberg M; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA; Linköping University, Linköping SE-581 83, Sweden.
Omodaka S; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Yang SY; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA.
Wong S; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA.
Rabiller G; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA.
Tominaga T; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Hsieh CL; SFVAMC, San Francisco, CA 94121, USA; Department of Medicine, UCSF, San Francisco, CA 94121, USA.
Liu J; Department of Neurological Surgery, UCSF, San Francisco, CA 94158, USA; SFVAMC, San Francisco, CA 94121, USA. Electronic address: .
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Źródło :
Experimental neurology [Exp Neurol] 2020 Dec; Vol. 334, pp. 113461. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CD36 Antigens/*biosynthesis
Diabetes Mellitus, Type 2/*metabolism
Lipoproteins, LDL/*metabolism
Animals ; CD36 Antigens/blood ; CD36 Antigens/genetics ; Cells, Cultured ; Diabetes Mellitus, Type 2/genetics ; Female ; Gene Expression ; Glucose/metabolism ; Glucose/toxicity ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Lipoproteins, LDL/blood ; Male ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Early Transcriptomic Response to OxLDL in Human Retinal Pigment Epithelial Cells.
Autorzy :
Koirala D; Department of Pharmaceutical Sciences; The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Beranova-Giorgianni S; Department of Pharmaceutical Sciences; The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Giorgianni F; Department of Pharmaceutical Sciences; The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 21; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*genetics
Lipoproteins, LDL/*metabolism
Macular Degeneration/*genetics
NF-E2-Related Factor 2/*genetics
Receptors, Aryl Hydrocarbon/*genetics
Aging/pathology ; Cell Line ; Cholesterol/metabolism ; Cholesterol, LDL/genetics ; Cholesterol, LDL/pharmacology ; Gene Expression Regulation/genetics ; Humans ; Lipoproteins, LDL/genetics ; Macula Lutea/metabolism ; Macula Lutea/pathology ; Macular Degeneration/drug therapy ; Macular Degeneration/metabolism ; Macular Degeneration/pathology ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/drug effects ; Phospholipids/metabolism ; Retinal Pigment Epithelium/metabolism ; Retinal Pigment Epithelium/pathology ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Polyphenols bind to low density lipoprotein at biologically relevant concentrations that are protective for heart disease.
Autorzy :
Tung WC; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Rizzo B; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Dabbagh Y; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Saraswat S; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Romanczyk M; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Codorniu-Hernández E; Department of Chemistry, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, T2N1N4, Canada.
Rebollido-Rios R; Research Group Bioinformatics, Faculty of Biology, Center for Medical Biotechnology, University of Duisburg-Essen, Universitätsstrase 1-5, 45141, Essen, Germany; Faculty of Medicine and University Hospital of Cologne, Department of Internal Medicine, University of Cologne, 50937, Cologne, Germany.
Needs PW; Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, NR4 7UQ, UK.
Kroon PA; Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, NR4 7UQ, UK.
Rakotomanomana N; Avignon University, INRAE, UMR408 SQPOV, 84000, Avignon, France.
Dangles O; Avignon University, INRAE, UMR408 SQPOV, 84000, Avignon, France.
Weikel K; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA.
Vinson J; Department of Chemistry, Loyola Science Center, University of Scranton, Scranton, PA, 18510, USA. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2020 Nov 15; Vol. 694, pp. 108589. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*pharmacology
Cardiotonic Agents/*pharmacology
Lipoproteins, LDL/*metabolism
Polyphenols/*pharmacology
Animals ; Antioxidants/metabolism ; Cardiotonic Agents/metabolism ; Humans ; Lipoproteins, LDL/chemistry ; Oxidation-Reduction/drug effects ; Polyphenols/metabolism ; Protein Binding ; Serum Albumin, Human/metabolism ; Swine
Czasopismo naukowe
Tytuł :
NET-associated citrullinated histones promote LDL aggregation and foam cell formation in vitro.
Autorzy :
Haritha VH; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, 686560, India. Electronic address: .
George A; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, 686560, India. Electronic address: .
Shaji BV; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, 686560, India. Electronic address: .
Anie Y; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, 686560, India. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Nov 15; Vol. 396 (2), pp. 112320. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Aggregates*/drug effects
Citrulline/*metabolism
Extracellular Traps/*metabolism
Foam Cells/*metabolism
Histones/*metabolism
Lipoproteins, LDL/*metabolism
Cell Movement/drug effects ; Extracellular Traps/drug effects ; Foam Cells/drug effects ; Humans ; Lipoproteins, LDL/pharmacology ; Neutrophils/drug effects ; Neutrophils/metabolism ; Oxidation-Reduction/drug effects
Czasopismo naukowe
Tytuł :
Affinity of chlordecone and chlordecol for human serum lipoproteins.
Autorzy :
Delannoy M; Université de Lorraine, INRAE, Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), USC 340, Nancy F-54000, France. Electronic address: .
Girardet JM; Université de Lorraine, INRAE, Interactions Arbres/Micro-organismes (IAM), UMR 1136, F-54000 Nancy, France.
Djelti F; Université de Lorraine, INRAE, Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), USC 340, Nancy F-54000, France.
Yen FT; Université de Lorraine, INRAE, Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), USC 340, Nancy F-54000, France.
Cakir-Kiefer C; Université de Lorraine, INRAE, Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), USC 340, Nancy F-54000, France.
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Źródło :
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2020 Nov; Vol. 80, pp. 103486. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Chlordecone/*chemistry
Insecticides/*chemistry
Lipoproteins, HDL/*chemistry
Lipoproteins, LDL/*chemistry
Chlordecone/metabolism ; Humans ; Insecticides/metabolism ; Lipoproteins, HDL/metabolism ; Lipoproteins, LDL/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
Aldehyde dehydrogenase 2 inhibited oxidized LDL-induced NLRP3 inflammasome priming and activation via attenuating oxidative stress.
Autorzy :
Xu Y; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China; School of Medicine, Shandong University, Jinan, China.
Yuan Q; Department of Cardiology, Ju-ye People's Hospital, Heze, China.
Cao S; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China.
Cui S; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China.
Xue L; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China.
Song X; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China; School of Basic Medicine, Shandong University, Jinan, China.
Li Z; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China; School of Basic Medicine, Shandong University, Jinan, China.
Xu R; School of Medicine, Shandong University, Jinan, China.
Yuan Q; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China. Electronic address: .
Li R; Department of Emergency, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital, Shandong University, Jinan, China; Key Laboratory of Cardiovascular Remodeling & Function Research, Chinese Ministry of Education & Chinese Ministry of Public Health, Qilu Hospital, Shandong University, Jinan, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Sep 03; Vol. 529 (4), pp. 998-1004. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aldehyde Dehydrogenase, Mitochondrial/*genetics
Anti-Inflammatory Agents/*pharmacology
Benzamides/*pharmacology
Benzodioxoles/*pharmacology
Inflammasomes/*drug effects
Lipoproteins, LDL/*antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein/*genetics
Aldehyde Dehydrogenase, Mitochondrial/metabolism ; Aldehydes/antagonists & inhibitors ; Aldehydes/metabolism ; Animals ; Caspase 1/genetics ; Caspase 1/metabolism ; DNA Damage ; Gene Expression Regulation ; Humans ; Inflammasomes/metabolism ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Lipoproteins, LDL/pharmacology ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein/antagonists & inhibitors ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Oxidative Stress/drug effects ; Pyroptosis/drug effects ; Pyroptosis/genetics ; RAW 264.7 Cells ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
miRNA-mediated macrophage behaviors responding to matrix stiffness and ox-LDL.
Autorzy :
Li J; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Key Laboratory on Space Physics and Chemistry of Ministry of Education and Key Laboratory on Macromolecular Science & Technology of Shanxi Province, Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Wang S; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Li Y; Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.; The Key Library of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.
Zhang N; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Gribskov M; Department of Biological Sciences, Purdue University, West Lafayette, Indiana.; Department of Computer Science, Purdue University, West Lafayette, Indiana.
Zhang X; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Lin M; Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.; The Key Library of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.
Shao D; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Zhang C; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Dai L; Institute of Medical Research, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Qin C; Key Laboratory on Space Physics and Chemistry of Ministry of Education and Key Laboratory on Macromolecular Science & Technology of Shanxi Province, Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Duan X; Second Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, P.R. China.; Institute of Medical Research, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
Li J; Collaborative Innovation Centre of Medical Engineering, Luoyang, Henan, China.
Xu F; Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.; The Key Library of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.
Yang H; School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.; Center of Special Environmental Biomechanics & Biomedical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, P.R. China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Sep; Vol. 235 (9), pp. 6139-6153. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*genetics
Extracellular Matrix/*genetics
Lipoproteins, LDL/*genetics
MicroRNAs/*genetics
Apoptosis/genetics ; Atherosclerosis/pathology ; Cell Movement/genetics ; Cells, Cultured ; Extracellular Matrix/metabolism ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Lipoproteins, LDL/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Monocytes/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Anti-Inflammatory HDL Function, Incident Cardiovascular Events, and Mortality: A Secondary Analysis of the JUPITER Randomized Clinical Trial.
Autorzy :
Ajala ON; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.
Demler OV; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.
Liu Y; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.
Farukhi Z; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.
Adelman SJ; VascularStrategies Plymouth PA.
Collins HL; VascularStrategies Plymouth PA.
Ridker PM; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.; Division of Cardiovascular Medicine Brigham and Women's Hospital Boston MA.
Rader DJ; Department of Genetics University of Pennsylvania Philadelphia PA.
Glynn RJ; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.
Mora S; Center for Lipid Metabolomics and Division of Preventive Medicine Brigham and Women's Hospital Boston MA.; Harvard Medical School Boston MA.; Division of Cardiovascular Medicine Brigham and Women's Hospital Boston MA.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2020 Sep; Vol. 9 (17), pp. e016507. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Cardiovascular Diseases/*mortality
Cholesterol, HDL/*blood
Lipoproteins, LDL/*drug effects
Aged ; Anti-Inflammatory Agents/pharmacology ; Cardiovascular Diseases/blood ; Case-Control Studies ; Cholesterol, HDL/pharmacology ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Lipoproteins, LDL/blood ; Male ; Middle Aged ; Placebos/administration & dosage ; Risk Factors ; Rosuvastatin Calcium/therapeutic use
Czasopismo naukowe
Tytuł :
Binding to heparin triggers deleterious structural and biochemical changes in human low-density lipoprotein, which are amplified in hyperglycemia.
Autorzy :
Jayaraman S; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: .
Chavez OR; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA.
Pérez A; Endocrinology Department of the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Spain.
Miñambres I; Endocrinology Department of the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Sánchez-Quesada JL; CIBER of Diabetes and Metabolic Diseases (CIBERDEM), Spain; Cardiovascular Biochemistry Group, Research Institute of the Hospital de Sant Pau, CIBERDEM, Barcelona, Spain.
Gursky O; Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA 02118, USA; Amyloidosis Treatment and Research Center, Boston University School of Medicine, Boston MA, USA.
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2020 Aug; Vol. 1865 (8), pp. 158712. Date of Electronic Publication: 2020 Apr 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*metabolism
Heparin/*metabolism
Hyperglycemia/*metabolism
Lipoproteins, LDL/*metabolism
Binding Sites ; Humans ; Hydrolysis ; Lipoproteins, LDL/blood ; Lipoproteins, LDL/chemistry ; Particle Size ; Protein Aggregates ; Protein Conformation ; Surface Properties
Czasopismo naukowe
Tytuł :
Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles.
Autorzy :
Marchini JF; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.; Departamento de Clínica Médica Instituto Central do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo SP Brazil.
Manica A; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.; Instituto de Cardiologia/Fundação Universitária de Cardiologia Porto Alegre RS Brazil.
Crestani P; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
Dutzmann J; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
Folco EJ; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
Weber H; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
Libby P; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
Croce K; Cardiovascular Division Department of Medicine Brigham and Women's HospitalHarvard Medical School Boston MA.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2020 Aug 04; Vol. 9 (15), pp. e015878. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell-Derived Microparticles/*metabolism
Lipoproteins, LDL/*pharmacology
Macrophages/*metabolism
Thrombosis/*etiology
Flow Cytometry ; Humans ; Lipoproteins, LDL/metabolism ; Macrophages/drug effects ; Thrombin/metabolism ; Thromboplastin/metabolism
Czasopismo naukowe
Tytuł :
An implanted port-catheter system for repeated hepatic arterial infusion of low-density lipoprotein-docosahexaenoic acid nanoparticles in normal rats: A safety study.
Autorzy :
Wang Y; Department of Hepatobiliary and pancreatic surgery, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan 450003, China; Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.
Li J; Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.
Subramaniyan I; Department of Pharmaceutical Sciences, Department of Pharmacy Practice within the Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Dallas, TX 75235, USA.
do Vale GD; Department of Molecular Genetics, Dallas, TX 75390, USA.
Chaudhary J; Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.
Anwar A; Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.
Wight-Carter M; Animal Resource Center, Dallas, TX 75390, USA.
McDonald JG; Department of Molecular Genetics, Dallas, TX 75390, USA.
Putnam WC; Department of Pharmaceutical Sciences, Department of Pharmacy Practice within the Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Dallas, TX 75235, USA.
Qin T; Department of Hepatobiliary and pancreatic surgery, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan 450003, China.
Zhang H; Department of Hepatobiliary and pancreatic surgery, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan 450003, China.
Corbin IR; Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA; Internal Medicine Division of Liver and Digestive Diseases, Dallas, TX 75390, USA; RadiologyUniversity of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Aug 01; Vol. 400, pp. 115037. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepatic Artery*
Catheters, Indwelling/*adverse effects
Docosahexaenoic Acids/*administration & dosage
Infusions, Intra-Arterial/*adverse effects
Lipoproteins, LDL/*administration & dosage
Liver/*metabolism
Nanoparticles/*administration & dosage
Animals ; Blood Glucose/analysis ; Docosahexaenoic Acids/pharmacokinetics ; Infusions, Intra-Arterial/methods ; Kidney Function Tests ; Lipids/blood ; Lipoproteins, LDL/pharmacokinetics ; Liver/blood supply ; Liver Function Tests ; Male ; Rats, Wistar ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Targeted delivery of mitomycin C-loaded and LDL-conjugated mesoporous silica nanoparticles for inhibiting the proliferation of pterygium subconjunctival fibroblasts.
Autorzy :
Wu M; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, School of Shanghai Medicine, Fudan University, Shanghai, 200031, PR China.
Wang S; Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University, Shanghai, 200433, PR China.
Wang Y; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, School of Shanghai Medicine, Fudan University, Shanghai, 200031, PR China.
Zhang F; Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and iChem, Fudan University, Shanghai, 200433, PR China. Electronic address: .
Shao T; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, School of Shanghai Medicine, Fudan University, Shanghai, 200031, PR China. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2020 Aug; Vol. 197, pp. 108124. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipoproteins, LDL*
Silicon Dioxide*
Conjunctiva/*pathology
Mitomycin/*administration & dosage
Pterygium/*drug therapy
Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Conjunctiva/drug effects ; Cross-Linking Reagents/administration & dosage ; Drug Delivery Systems ; Female ; Fibroblasts/drug effects ; Fibroblasts/pathology ; Humans ; Male ; Middle Aged ; Nanoparticles ; Pterygium/diagnosis ; Pterygium/metabolism
Czasopismo naukowe
Tytuł :
Effects of NIX-mediated mitophagy on ox-LDL-induced macrophage pyroptosis in atherosclerosis.
Autorzy :
Peng X; Department of Pathology, Anhui Armed Police General Hospital, Hefei, 230032, Anhui, China.
Chen H; Department of Pathology, Anhui Armed Police General Hospital, Hefei, 230032, Anhui, China.
Li Y; Department of Immunology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Huang D; Department of Immunology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Huang B; Department of Immunology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Sun D; Department of General Surgery, Anhui Armed Police General Hospital, Hefei, 230032, Anhui, China.
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Źródło :
Cell biology international [Cell Biol Int] 2020 Jul; Vol. 44 (7), pp. 1481-1490. Date of Electronic Publication: 2020 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Atherosclerosis/*pathology
Autophagy/*drug effects
Lipoproteins, LDL/*pharmacology
Macrophages/*drug effects
Mitochondria/*drug effects
Atherosclerosis/chemically induced ; Atherosclerosis/metabolism ; Cell Death/drug effects ; Humans ; Inflammasomes/drug effects ; Inflammasomes/metabolism ; Lipoproteins, LDL/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł :
Biomimetic sensors targeting oxidized-low-density lipoprotein with molecularly imprinted polymers.
Autorzy :
Chunta S; Department of Clinical Chemistry, Faculty of Medical Technology, Prince of Songkla University, Hatyai, Songkla, 90110, Thailand.
Suedee R; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hatyai, Songkla, 90110, Thailand.
Boonsriwong W; Faculty of Medical Technology, Nation University, Mueang, Lampang, 52000, Thailand.
Lieberzeit PA; Department of Physical Chemistry, Faculty for Chemistry, University of Vienna, Währinger Straße 42, A-1090, Vienna, Austria. Electronic address: .
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2020 Jun 15; Vol. 1116, pp. 27-35. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Lipoproteins, LDL/*blood
Molecularly Imprinted Polymers/*chemistry
Biomimetics/methods ; Humans ; Lipoproteins, LDL/chemistry ; Molecular Imprinting ; Polymethacrylic Acids/chemistry ; Povidone/analogs & derivatives ; Quartz Crystal Microbalance Techniques/methods
Czasopismo naukowe
Tytuł :
The role of oxidation of low-density lipids in pathogenesis of osteoarthritis: A narrative review.
Autorzy :
Hashimoto K; Department of Orthopaedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka, Japan.
Akagi M; Department of Orthopaedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka, Japan.
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Źródło :
The Journal of international medical research [J Int Med Res] 2020 Jun; Vol. 48 (6), pp. 300060520931609.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lipoproteins, LDL/*physiology
Osteoarthritis/*pathology
Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cartilage, Articular/pathology ; Chondrocytes/metabolism ; Humans ; Knee Joint/pathology ; Lipoproteins, LDL/metabolism ; Osteoarthritis/metabolism ; Oxidation-Reduction
Czasopismo naukowe

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