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Tytuł :
Overcoming the hypoxia-induced drug resistance in liver tumor by the concurrent use of apigenin and paclitaxel.
Autorzy :
Li K; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Li M; School of Life Science, Chongqing University, Chongqing, 401331, China.
Luo Z; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China; School of Life Science, Chongqing University, Chongqing, 401331, China. Electronic address: .
Mao Y; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Yu Y; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
He Y; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Zhou J; School of Life Science, Chongqing University, Chongqing, 401331, China.
Fei Y; School of Life Science, Chongqing University, Chongqing, 401331, China.
Pei Y; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Cai K; Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 May 28; Vol. 526 (2), pp. 321-327. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Apigenin/*pharmacology
Cell Hypoxia/*drug effects
Drug Resistance, Neoplasm/*drug effects
Liver Neoplasms/*drug therapy
Paclitaxel/*pharmacology
Animals ; Antineoplastic Agents, Phytogenic/administration & dosage ; Apigenin/administration & dosage ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Hep G2 Cells ; Humans ; Injections, Intravenous ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Liver Neoplasms, Experimental/drug therapy ; Liver Neoplasms, Experimental/metabolism ; Liver Neoplasms, Experimental/pathology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Paclitaxel/administration & dosage ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Autorzy :
Lin YH; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Zhang S; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Zhu M; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Lu T; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Chen K; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Wen Z; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Wang S; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Xiao G; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Luo D; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Jia Y; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Li L; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
MacConmara M; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.
Hoshida Y; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Singal AG; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Yopp A; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.
Wang T; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas; Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas.
Zhu H; Children's Research Institute, Departments of Pediatrics and Internal Medicine, Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2020 May; Vol. 158 (6), pp. 1698-1712.e14. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Polyploidy*
Carcinoma, Hepatocellular/*genetics
Hepatocytes/*physiology
Liver Neoplasms/*genetics
Liver Regeneration/*genetics
Animals ; Carbon Tetrachloride/toxicity ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/pathology ; Cells, Cultured ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/pathology ; Diethylnitrosamine/toxicity ; Female ; Gene Knockdown Techniques ; Hepatectomy ; Hepatocytes/drug effects ; Humans ; Liver/cytology ; Liver/drug effects ; Liver/pathology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Liver Neoplasms/chemically induced ; Liver Neoplasms/pathology ; Liver Neoplasms, Experimental/chemically induced ; Liver Neoplasms, Experimental/genetics ; Liver Neoplasms, Experimental/pathology ; Liver Regeneration/drug effects ; Male ; Mice ; Mice, Transgenic ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Primary Cell Culture ; Protective Factors ; RNA-Seq ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Comparison of Liver Transplantation and Liver Resection for Hepatocellular Carcinoma Patients with Portal Vein Tumor Thrombus Type I and Type II.
Autorzy :
Lv JY; The First Central Clinical College of Tianjin Medical University, Tianjin, China.
Zhang NN; Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Department of Hepatobiliary Surgery, Tianjin First Central Hospital, Tianjin Key Laboratory for Organ Transplantation, Tianjin, China.; Post-doctoral Research Center, Nankai University, Tianjin, China.
Du YW; Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Wu Y; School of Statistics and Data Science, Nankai University, Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin, Tianjin, China.
Song TQ; Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Zhang YM; Department of Hepatobiliary Surgery, Tianjin First Central Hospital, Tianjin Key Laboratory for Organ Transplantation, Tianjin, China.
Qu Y; School of Statistics and Data Science, Nankai University, Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin, Tianjin, China.
Liu YX; School of Statistics and Data Science, Nankai University, Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin, Tianjin, China.
Gu J; The First Central Clinical College of Tianjin Medical University, Tianjin, China.
Wang ZY; Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Qiu YB; The First Central Clinical College of Tianjin Medical University, Tianjin, China.
Yang B; The First Central Clinical College of Tianjin Medical University, Tianjin, China.
Tian DZ; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Guo QJ; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Zhang L; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Sun JS; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Xie Y; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Wang ZL; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Sun X; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China.
Jiang WT; Department of Liver Transplantation, Tianjin First Central Hospital, NHC Key Laboratory for Critical Care Medicine, Key Laboratory of Transplantation, Chinese Academy of Medical Sciences, Tianjin, China. .
Lu W; Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Tianjin Second People's Hospital, Tianjin Medical Research Institute of Liver Disease, Tianjin, China. .
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Źródło :
Yonsei medical journal [Yonsei Med J] 2021 Jan; Vol. 62 (1), pp. 29-40.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Hepatectomy*
Liver Transplantation*
Carcinoma, Hepatocellular/*complications
Carcinoma, Hepatocellular/*surgery
Liver Neoplasms/*complications
Liver Neoplasms/*surgery
Thrombosis/*complications
Adult ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Female ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Portal Vein/pathology ; Prognosis ; Retrospective Studies ; Risk Factors ; alpha-Fetoproteins/metabolism
Czasopismo naukowe
Tytuł :
APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases.
Autorzy :
Yamashita S; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Chun YS; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Kopetz SE; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Maru D; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Conrad C; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Aloia TA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Vauthey JN; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
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Źródło :
Annals of surgery [Ann Surg] 2020 Dec; Vol. 272 (6), pp. 1080-1085.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Adenomatous Polyposis Coli Protein/*genetics
Class I Phosphatidylinositol 3-Kinases/*genetics
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*mortality
Liver Neoplasms/*genetics
Liver Neoplasms/*mortality
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Colorectal Neoplasms/pathology ; Combined Modality Therapy ; Female ; Hepatectomy ; Humans ; Liver Neoplasms/secondary ; Liver Neoplasms/therapy ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł :
Platelet and neutrophil to lymphocyte ratios predict survival in patients with resectable colorectal liver metastases.
Autorzy :
Erstad DJ; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Taylor MS; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Qadan M; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Axtell AL; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; Codman Center for Clinical Effectiveness in Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Fuchs BC; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Berger DL; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Clancy TE; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Tanabe KK; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Chang DC; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; Codman Center for Clinical Effectiveness in Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Ferrone CR; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: .
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Źródło :
American journal of surgery [Am J Surg] 2020 Dec; Vol. 220 (6), pp. 1579-1585. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Lymphocytes*
Neutrophils*
Colorectal Neoplasms/*blood
Colorectal Neoplasms/*mortality
Liver Neoplasms/*blood
Liver Neoplasms/*mortality
Adult ; Aged ; Colorectal Neoplasms/pathology ; Female ; Hepatectomy ; Humans ; Leukocyte Count ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Platelet Count ; Predictive Value of Tests ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Prognostic value of γ-glutamyl transpeptidase to albumin ratio combined with aspartate aminotransferase to lymphocyte ratio in patients with hepatocellular carcinoma after hepatectomy.
Autorzy :
Liu KJ; School of Clinical Medicine, Ningxia Medical University.
Lv YX; School of Basic Medicine, Ningxia Medical University.
Niu YM; School of Clinical Medicine, Ningxia Medical University.
Bu Y; School of Clinical Medicine, Ningxia Medical University.; Department of Hepatobiliary Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Nov 25; Vol. 99 (48), pp. e23339.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*blood
Carcinoma, Hepatocellular/*surgery
Liver Neoplasms/*blood
Liver Neoplasms/*surgery
Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking/epidemiology ; Aspartate Aminotransferases/blood ; Biomarkers ; Carcinoma, Hepatocellular/epidemiology ; Carcinoma, Hepatocellular/mortality ; Female ; Hepatectomy ; Humans ; Kaplan-Meier Estimate ; Liver Neoplasms/epidemiology ; Liver Neoplasms/mortality ; Lymphocytes/metabolism ; Male ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Prognosis ; ROC Curve ; Retrospective Studies ; Serum Albumin/analysis ; Sex Factors ; Smoking/epidemiology ; gamma-Glutamyltransferase/blood
Czasopismo naukowe
Tytuł :
Long noncoding RNA PICSAR/miR-588/EIF6 axis regulates tumorigenesis of hepatocellular carcinoma by activating PI3K/AKT/mTOR signaling pathway.
Autorzy :
Liu Z; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Mo H; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Sun L; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang L; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Chen T; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yao B; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liu R; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Niu Y; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Tu K; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xu Q; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital (People's Hospital of Hangzhou Medical College), Hangzhou, China.
Yang N; Department of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Nov; Vol. 111 (11), pp. 4118-4128. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Signal Transduction*
Carcinoma, Hepatocellular/*genetics
Carcinoma, Hepatocellular/*metabolism
Cell Transformation, Neoplastic/*genetics
Cell Transformation, Neoplastic/*metabolism
Liver Neoplasms/*genetics
Liver Neoplasms/*metabolism
Animals ; Apoptosis/genetics ; Biomarkers, Tumor ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Disease Models, Animal ; Female ; Humans ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Male ; Mice ; MicroRNAs/genetics ; Peptide Initiation Factors/genetics ; Peptide Initiation Factors/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Prognosis ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Long Noncoding/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Autorzy :
Xiang L; Unit of Hepatobiliary Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China.
Huang X; Department of Radiation Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China.
Wang S; Department of gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ou H; Department of Hepatobiliary Surgery, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, China.
Chen Z; Unit of Hepatobiliary Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of General Surgery, Affiliated Baoan Hospital of Shenzhen, Southern Medical University, Shenzhen, China.
Hu Z; Unit of Hepatobiliary Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Huang Y; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Li X; Unit of Hepatobiliary Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuan Y; Department of Radiation Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China.
Yang D; Unit of Hepatobiliary Surgery, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Nov; Vol. 111 (11), pp. 4102-4117. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Deletion*
Carcinoma, Hepatocellular/*genetics
Carcinoma, Hepatocellular/*pathology
Liver Neoplasms/*genetics
Liver Neoplasms/*pathology
RNA, Long Noncoding/*genetics
Zinc Finger E-box-Binding Homeobox 1/*genetics
Aged ; Animals ; Biomarkers ; Biomarkers, Tumor ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/mortality ; Cell Line, Tumor ; Cell Movement ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Liver Neoplasms/metabolism ; Liver Neoplasms/mortality ; Male ; Mice ; Middle Aged ; Prognosis ; Pseudogenes ; Zinc Finger E-box-Binding Homeobox 1/metabolism
Czasopismo naukowe
Tytuł :
Hepatocellular carcinoma surveillance in Australia: time to improve the diagnosis of cirrhosis and use liver ultrasound.
Autorzy :
Jeffrey GP; University of Western Australia, Perth, WA.
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Źródło :
The Medical journal of Australia [Med J Aust] 2020 Nov; Vol. 213 (9), pp. 432-432.e1. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Letter; Comment
MeSH Terms :
Carcinoma, Hepatocellular*/diagnostic imaging
Carcinoma, Hepatocellular*/epidemiology
Liver Neoplasms*/diagnostic imaging
Liver Neoplasms*/epidemiology
Australia/epidemiology ; Humans ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/epidemiology ; Ultrasonography
Opinia redakcyjna
Tytuł :
Icaritin-induced immunomodulatory efficacy in advanced hepatitis B virus-related hepatocellular carcinoma: Immunodynamic biomarkers and overall survival.
Autorzy :
Qin SK; Clinical Oncology Department, Nanjing Jinling Hospital, Nanjing, China.
Li Q; National Cancer Center/National Clinical Research Center, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Ming Xu J; The 5th Medical Centre, Chinese PLA General Hospital, Beijing, China.
Liang J; Clinical Oncology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Cheng Y; Clinical Oncology Department, Jilin Cancer Hospital, Changchun, China.
Fan Y; National Cancer Center/National Clinical Research Center, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Jiang J; National Cancer Center/National Clinical Research Center, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Ye H; Research & Development Department, SinoTech Genomics, Shanghai, China.
Tao H; School of Life Science, Sun Yat-Sen University, Guangzhou, China.
Li L; School of Life Science, Sun Yat-Sen University, Guangzhou, China.
Zheng L; School of Life Science, Sun Yat-Sen University, Guangzhou, China.
Wei Z; Biostatistical Department, Tigermed Consulting Co., Ltd., Shanghai, China.
Li S; Research & Clinical Development, Shenogen Pharma Group, Beijing, China.
Meng K; Research & Clinical Development, Shenogen Pharma Group, Beijing, China.
Ye B; Research & Clinical Development, Shenogen Pharma Group, Beijing, China.
Sun Y; National Cancer Center/National Clinical Research Center, Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Nov; Vol. 111 (11), pp. 4218-4231. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*etiology
Carcinoma, Hepatocellular/*metabolism
Flavonoids/*pharmacology
Hepatitis B/*complications
Immunomodulation/*drug effects
Liver Neoplasms/*etiology
Liver Neoplasms/*metabolism
Animals ; Biomarkers ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Clinical Trials, Phase II as Topic ; Cytokines ; Disease Models, Animal ; Flavonoids/therapeutic use ; Humans ; Kaplan-Meier Estimate ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Lymphocyte Activation ; Mice ; Multicenter Studies as Topic ; Myeloid-Derived Suppressor Cells/drug effects ; Myeloid-Derived Suppressor Cells/immunology ; Myeloid-Derived Suppressor Cells/metabolism ; Neoplasm Staging ; Prognosis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Hepatocellular carcinoma surveillance in Australia: time to improve the diagnosis of cirrhosis and use liver ultrasound.
Autorzy :
Larcos G; Westmead Hospital, Sydney, NSW.
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Źródło :
The Medical journal of Australia [Med J Aust] 2020 Nov; Vol. 213 (9), pp. 431-431.e1. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Letter; Comment
MeSH Terms :
Carcinoma, Hepatocellular*/diagnostic imaging
Carcinoma, Hepatocellular*/epidemiology
Liver Neoplasms*/diagnostic imaging
Liver Neoplasms*/epidemiology
Australia/epidemiology ; Humans ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/epidemiology ; Ultrasonography
Opinia redakcyjna
Tytuł :
Immune-related microRNA signature for predicting prognosis and the immune microenvironment in hepatocellular carcinoma.
Autorzy :
Li Y; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China.
He X; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China.
Zhang X; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China.
Xu Y; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China.
Wu Y; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China. Electronic address: .
Xu X; Cancer Center, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan 430060, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118799. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*immunology
Carcinoma, Hepatocellular/*immunology
Liver Neoplasms/*immunology
MicroRNAs/*immunology
Tumor Microenvironment/*immunology
Aged ; Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/genetics ; Female ; Humans ; Liver Neoplasms/diagnosis ; Liver Neoplasms/genetics ; Male ; MicroRNAs/genetics ; Middle Aged ; Prognosis ; Retrospective Studies ; Transcriptome ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
[Current state of hepatocellular carcinoma surveillance for chronic liver disease in 91 cases of primary hepatocellular carcinoma].
Autorzy :
Kurosugi A; Department of Gastroenterology, Eastern Chiba Medical Center.; Department of Gastroenterology, Chiba University Hospital.
Kamezaki H; Department of Gastroenterology, Eastern Chiba Medical Center.
Iwanaga T; Department of Gastroenterology, Eastern Chiba Medical Center.; Department of Gastroenterology, Chiba University Hospital.
Senoo J; Department of Gastroenterology, Eastern Chiba Medical Center.
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Źródło :
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology [Nihon Shokakibyo Gakkai Zasshi] 2021; Vol. 118 (1), pp. 55-60.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular*/diagnostic imaging
Carcinoma, Hepatocellular*/epidemiology
Carcinoma, Hepatocellular*/etiology
Liver Neoplasms*/epidemiology
Liver Neoplasms*/etiology
Humans ; Liver Cirrhosis ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Prognostic Value of Alpha-Fetoprotein in Patients Who Achieve a Complete Response to Transarterial Chemoembolization for Hepatocellular Carcinoma.
Autorzy :
Lee JS; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Chon YE; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Kim BK; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Park JY; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Kim DY; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Ahn SH; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Han KH; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea.
Kang W; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Choi MS; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Gwak GY; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Paik YH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee JH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Koh KC; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Paik SW; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim HY; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Kim TH; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Yoo K; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Ha Y; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Kim MN; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Lee JH; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Hwang SG; Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Kim SS; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
Cho HJ; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
Cheong JY; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
Cho SW; Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
Park SH; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.
Heo NY; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea.
Hong YM; Liver Center, Pusan National University Yangsan Hospital, Yangsan, Korea.
Yoon KT; Liver Center, Pusan National University Yangsan Hospital, Yangsan, Korea.
Cho M; Liver Center, Pusan National University Yangsan Hospital, Yangsan, Korea.
Park JG; Department of Internal Medicine, Yeungnam University Medical Centre, Daegu, Korea.
Kang MK; Department of Internal Medicine, Yeungnam University Medical Centre, Daegu, Korea.
Park SY; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Kweon YO; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Tak WY; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Jang SY; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Sinn DH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. .
Kim SU; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Yonsei Liver Center, Severance Hospital, Seoul, Korea. .
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Corporate Authors :
Korean TACE Study Group
Źródło :
Yonsei medical journal [Yonsei Med J] 2021 Jan; Vol. 62 (1), pp. 12-20.
Typ publikacji :
Journal Article
MeSH Terms :
Arteries*
Chemoembolization, Therapeutic*/adverse effects
Carcinoma, Hepatocellular/*therapy
Liver Neoplasms/*therapy
alpha-Fetoproteins/*metabolism
Adult ; Aged ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/metabolism ; Female ; Humans ; Liver Neoplasms/diagnosis ; Liver Neoplasms/metabolism ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Recurrence ; Treatment Outcome ; Venous Thrombosis/etiology
Czasopismo naukowe
Tytuł :
Chapter XX Antiviral Treatment and Cancer Control.
Autorzy :
Shih WL; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Fang CT; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Chen PJ; Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan. .
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Źródło :
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer [Recent Results Cancer Res] 2021; Vol. 217, pp. 325-354.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Carcinoma, Hepatocellular*/prevention & control
Carcinoma, Hepatocellular*/virology
Herpesvirus 8, Human*
Liver Neoplasms*/prevention & control
Liver Neoplasms*/virology
Adult ; Herpesvirus 4, Human ; Humans ; Neoplasms/prevention & control ; Neoplasms/virology
Czasopismo naukowe
Tytuł :
Notch Signaling and Liver Cancer.
Autorzy :
Kawaguchi K; Department of Gastroenterology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Kaneko S; Department of Gastroenterology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan. .
Pokaż więcej
Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1287, pp. 69-80.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Liver Neoplasms*/metabolism
Liver Neoplasms*/virology
Signal Transduction*
Receptors, Notch/*metabolism
Hepatitis/metabolism ; Hepatitis/virology ; Hepatitis B virus/pathogenicity ; Humans ; Repressor Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Trans-chalcone induces death by autophagy mediated by p53 up-regulation and β-catenin down-regulation on human hepatocellular carcinoma HuH7.5 cell line.
Autorzy :
Siqueira EDS; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil. Electronic address: .
Concato VM; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
Tomiotto-Pellissier F; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitiba, Paraná, Brazil.
Silva TF; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
Bortoleti BTDS; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitiba, Paraná, Brazil.
Gonçalves MD; Laboratory of Biotransformation and Phytochemistry, State University of Londrina, Paraná, Brazil.
Costa IN; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
Junior WAV; Laboratory of Research for Pain, Neuropathy and Inflammation, State University of Londrina, Paraná, Brazil.
Pavanelli WR; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
Panis C; Laboratory of Tumor of Biology, State University of West Paraná, Francisco Beltrão, Paraná, Brazil.
Mantovani MS; Laboratory of Toxicological Genetics, State University of Londrina, PR, Brazil.
Miranda-Sapla MM; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
Conchon-Costa I; Laboratory of Immunopathology of Neglected Diseases and Cancer, State University of Londrina - UEL. Rodovia Celso Garcia Cid Campus Zip Code 86057-970, Post Box 10.011. Londrina, PR, Brazil.
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jan; Vol. 80, pp. 153373. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*drug therapy
Chalcone/*pharmacology
Chalcones/*pharmacology
Liver Neoplasms/*drug therapy
Tumor Suppressor Protein p53/*metabolism
beta Catenin/*metabolism
Apoptosis/drug effects ; Autophagy/drug effects ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Down-Regulation/drug effects ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Oxysophocarpine suppresses FGFR1-overexpressed hepatocellular carcinoma growth and sensitizes the therapeutic effect of lenvatinib.
Autorzy :
Zhao Z; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China.
Song J; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China.
Zhang D; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China.
Wu F; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China.
Tu J; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China.
Ji J; Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University/Affiliated Lishui Hospital of Zhejiang University/The Central Hospital of Zhejiang Lishui, Lishui 323000, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118642. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*therapeutic use
Carcinoma, Hepatocellular/*drug therapy
Carcinoma, Hepatocellular/*pathology
Liver Neoplasms/*drug therapy
Liver Neoplasms/*pathology
Receptor, Fibroblast Growth Factor, Type 1/*metabolism
Alkaloids/pharmacology ; Animals ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Liver Neoplasms/genetics ; MAP Kinase Signaling System/drug effects ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Phenylurea Compounds ; Proto-Oncogene Proteins c-akt/metabolism ; Quinolines ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
c-Src promotes the growth and tumorigenesis of hepatocellular carcinoma via the Hippo signaling pathway.
Autorzy :
Yang J; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China.
Zhang X; Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China. Electronic address: .
Liu L; Department of Ultrasound, The Second People's Hospital of Fujian Province, Fuzhou 350001, Fujian, China.
Yang X; Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China.
Qian Q; Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China.
Du B; Department of Oncology, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian, China.
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118711. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*/drug effects
Carcinogenesis/*metabolism
Carcinogenesis/*pathology
Carcinoma, Hepatocellular/*enzymology
Carcinoma, Hepatocellular/*pathology
Liver Neoplasms/*enzymology
Liver Neoplasms/*pathology
Protein-Serine-Threonine Kinases/*metabolism
Proto-Oncogene Proteins pp60(c-src)/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Carcinogenesis/drug effects ; Carcinogenesis/genetics ; Carcinoma, Hepatocellular/genetics ; Cell Cycle Checkpoints/drug effects ; Cell Cycle Checkpoints/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Movement/genetics ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Liver Neoplasms/genetics ; Male ; Mice, Nude ; Neoplasm Invasiveness ; Prognosis ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins pp60(c-src)/antagonists & inhibitors ; Proto-Oncogene Proteins pp60(c-src)/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription, Genetic/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Hepatocellular carcinoma with type II-III portal vein tumour thrombosis: treatment using transarterial chemoembolisation and microwave ablation.
Autorzy :
Zhao WP; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Li H; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Guo J; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Cai L; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Duan Y; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Hou X; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Du H; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Shao X; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Diao Z; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Li C; Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Pokaż więcej
Źródło :
The British journal of radiology [Br J Radiol] 2021 Jan 01; Vol. 94 (1117), pp. 20200415. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Ablation Techniques/*methods
Carcinoma, Hepatocellular/*therapy
Chemoembolization, Therapeutic/*methods
Liver Neoplasms/*therapy
Portal Vein/*pathology
Venous Thrombosis/*therapy
Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/surgery ; Combined Modality Therapy/methods ; Female ; Follow-Up Studies ; Humans ; Liver/surgery ; Liver Neoplasms/complications ; Liver Neoplasms/surgery ; Male ; Microwaves ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery
Czasopismo naukowe

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