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Wyszukujesz frazę ""Liver X Receptors"" wg kryterium: Temat


Tytuł:
Relationships of Liver X Receptor Antagonists and Atherosclerosis in Drinking Water from Six Chinese Major Cities.
Autorzy:
Shen X; MOE Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, People's Republic of China.
Li Q; MOE Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, People's Republic of China.
Hu W; MOE Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, People's Republic of China.
Yang M; State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
An W; State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Hu J; MOE Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, People's Republic of China.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2023 Dec 05; Vol. 57 (48), pp. 19374-19382. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/chemically induced
Atherosclerosis*/metabolism
Drinking Water*
Liver X Receptors*/antagonists & inhibitors
Humans ; China ; Cholesterol/metabolism ; Cities
Czasopismo naukowe
Tytuł:
Activation of LXRs alleviates neuropathic pain-induced cognitive dysfunction by modulation of microglia polarization and synaptic plasticity via PI3K/AKT pathway.
Autorzy:
Han S; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China.
Yuan X; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China.
Zhao F; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China.
Manyande A; School of Human and Social Sciences, University of West London, London, UK.
Gao F; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China.
Wang J; Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei Province, China.
Zhang W; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China. .
Tian X; Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, Hubei Province, China. .
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Źródło:
Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2024 Feb; Vol. 73 (2), pp. 157-174. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Neuralgia*/drug therapy
Cognitive Dysfunction*/drug therapy
Benzenesulfonamides*
Fluorocarbons*
Humans ; Mice ; Animals ; Liver X Receptors/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Microglia/metabolism ; Neuroinflammatory Diseases ; Neuronal Plasticity
Czasopismo naukowe
Tytuł:
Microwave-Promoted Total Synthesis of Puniceloid D for Modulating the Liver X Receptor.
Autorzy:
Jung YJ; College of Pharmacy, Kyungsung University, Busan 48434, Republic of Korea.
Hosseininasab N; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Park J; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Hyun S; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Jung JK; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Kwak JH; College of Pharmacy, Kyungsung University, Busan 48434, Republic of Korea.; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 15; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolic Syndrome*
Biological Products*/pharmacology
Humans ; Liver X Receptors ; Microwaves ; Head
Czasopismo naukowe
Tytuł:
The activation of liver X receptors in Madin-Darby bovine kidney cells and mice restricts infection by bovine viral diarrhea virus.
Autorzy:
Cui Y; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China.
Yuan X; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China.
Zhao Z; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China.
Li C; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China.
Liu Y; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China; Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, Daqing, China; Heilongjiang Province Cultivating Collaborative Innovation Center for The Beidahuang Modern Agricultural Industry Technology, Daqing, China.
Zhou Y; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China; Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, Daqing, China; Heilongjiang Province Cultivating Collaborative Innovation Center for The Beidahuang Modern Agricultural Industry Technology, Daqing, China.
Zhu Z; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China; Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, Daqing, China; Heilongjiang Province Cultivating Collaborative Innovation Center for The Beidahuang Modern Agricultural Industry Technology, Daqing, China. Electronic address: .
Zhang Z; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China; Heilongjiang Provincial Technology Innovation Center for Bovine Disease Control and Prevention, Daqing, China; Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, Daqing, China; Heilongjiang Province Cultivating Collaborative Innovation Center for The Beidahuang Modern Agricultural Industry Technology, Daqing, China. Electronic address: .
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Źródło:
Veterinary microbiology [Vet Microbiol] 2024 Jan; Vol. 288, pp. 109948. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Diarrhea Viruses, Bovine Viral*/genetics
Diarrhea Virus 1, Bovine Viral*
Cattle ; Animals ; Mice ; Cell Line ; Liver X Receptors ; Virus Replication/genetics ; Kidney ; Antiviral Agents/pharmacology ; Cholesterol ; Diarrhea/veterinary
Czasopismo naukowe
Tytuł:
Insulin Downregulates the Expression of ATP-binding Cassette Transporter A-I in Human Hepatoma Cell Line HepG2 in a FOXO1 and LXR Dependent Manner.
Autorzy:
Shavva VS; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.
Babina AV; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.
Nekrasova EV; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.
Lisunov AV; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.; Department of Embryology, St. Petersburg State University, St. Petersburg, Russia.
Dizhe EB; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.
Oleinikova GN; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia.
Orlov SV; Department of Biochemistry, Institute of Experimental Medicine, St. Petersburg, Russia. .; Department of Embryology, St. Petersburg State University, St. Petersburg, Russia. .
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Źródło:
Cell biochemistry and biophysics [Cell Biochem Biophys] 2023 Mar; Vol. 81 (1), pp. 151-160. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
ATP Binding Cassette Transporter 1*/genetics
Insulin*/metabolism
Liver X Receptors*/genetics
Liver X Receptors*/metabolism
Orphan Nuclear Receptors*/genetics
Orphan Nuclear Receptors*/metabolism
Animals ; Humans ; Mice ; Carcinoma, Hepatocellular ; Cell Line ; Forkhead Box Protein O1/genetics ; Forkhead Box Protein O1/metabolism ; Liver Neoplasms ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway.
Autorzy:
Yan H; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Liu Y; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Li X; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Yu B; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
He J; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Mao X; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Yu J; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Huang Z; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Luo Y; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Luo J; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Wu A; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Chen D; Key Laboratory of Animal Disease Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease resistant Nutrition of Sichuan Province, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
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Źródło:
ELife [Elife] 2024 Mar 05; Vol. 12. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokine Release Syndrome*
Interleukin-4*
Animals ; Mice ; Liver X Receptors ; Leucine/pharmacology ; Lipopolysaccharides ; Cytokines ; Signal Transduction ; Macrophages ; Mechanistic Target of Rapamycin Complex 1
Czasopismo naukowe
Tytuł:
Liver X Receptor Agonist 4β-Hydroxycholesterol as a Prognostic Factor in Coronary Artery Disease.
Autorzy:
Rahunen R; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Biocenter Oulu University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Tulppo M; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Rinne V; Admescope (Symeres Finland Ltd) Oulu Finland.
Lepojärvi S; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Perkiömäki JS; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Huikuri HV; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Ukkola O; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Junttila J; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Biocenter Oulu University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
Hukkanen J; Research Unit of Biomedicine and Internal Medicine University of Oulu Oulu Finland.; Biocenter Oulu University of Oulu Oulu Finland.; Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
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Źródło:
Journal of the American Heart Association [J Am Heart Assoc] 2024 Mar 05; Vol. 13 (5), pp. e031824. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Coronary Artery Disease*
Hydroxycholesterols*
Male ; Humans ; Female ; Liver X Receptors ; Prognosis ; Death ; Death, Sudden, Cardiac/epidemiology ; Risk Factors
Czasopismo naukowe
Tytuł:
Discovery of Anti-Hypercholesterolemia Agents Targeting LXRα from Marine Microorganism-Derived Natural Products.
Autorzy:
Fang Y; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
She J; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Zhang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Gu T; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Xie D; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Luo X; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Yi X; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Gao C; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Liu Y; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Zhang C; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Tang L; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhou X; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
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Źródło:
Journal of natural products [J Nat Prod] 2024 Feb 23; Vol. 87 (2), pp. 322-331. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypercholesterolemia*/drug therapy
Orphan Nuclear Receptors*/metabolism
Orphan Nuclear Receptors*/pharmacology
Animals ; Mice ; Cholesterol/metabolism ; Liver ; Liver X Receptors/metabolism ; Mice, Knockout ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Combining PLGA microspheres loaded with Liver X receptor agonist GW3965 with a chitosan nerve conduit can promote the healing and regeneration of the wounded sciatic nerve.
Autorzy:
Zhong Y; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Li S; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Chen Y; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Tang Y; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xiao X; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Nie T; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
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Źródło:
Journal of biomedical materials research. Part B, Applied biomaterials [J Biomed Mater Res B Appl Biomater] 2024 Feb; Vol. 112 (2), pp. e35378.
Typ publikacji:
Journal Article
MeSH Terms:
Chitosan*/pharmacology
Peripheral Nerve Injuries*/drug therapy
Benzoates*
Benzylamines*
Rats ; Animals ; Liver X Receptors/therapeutic use ; Microspheres ; Schwann Cells ; Sciatic Nerve/injuries ; Nerve Regeneration
Czasopismo naukowe
Tytuł:
Fermented natto powder alleviates obesity by regulating LXR pathway and gut microbiota in obesity rats.
Autorzy:
Sun R; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.; Future Food (Bai Ma) Research Institute, Nanjing 211200, Jiangsu, China.
Niu H; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Li Y; Science and Technology Exchange and Cooperation Division, Jilin Academy of Agricultural Sciences, Changchun 130033, Jilin, China.
Sun M; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Hua M; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Miao X; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Su Y; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Wang J; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Li D; Institute of Agro-product Process, Jilin Academy of Agricultural Science, Changchun 130033, Jilin, China.
Wang Y; Institute of Agricultural Quality Standards and Testing Technology, Liaoning Academy of Agricultural Sciences, Shenyang 110000, Liaoning, China.
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Źródło:
Journal of applied microbiology [J Appl Microbiol] 2024 Feb 01; Vol. 135 (2).
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
Soy Foods*
Rats ; Animals ; Mice ; Powders/pharmacology ; Liver X Receptors ; Rats, Sprague-Dawley ; Obesity/microbiology ; Diet, High-Fat ; Cholesterol/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Cornelian Cherry ( Cornus mas L.) Fruit Extract Lowers SREBP-1c and C/EBPα in Liver and Alters Various PPAR-α, PPAR-γ, LXR-α Target Genes in Cholesterol-Rich Diet Rabbit Model.
Autorzy:
Danielewski M; Department of Pharmacology, Wroclaw Medical University, J. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.
Rapak A; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland.
Kruszyńska A; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland.
Małodobra-Mazur M; Department of Forensic Medicine, Division of Molecular Techniques, Wroclaw Medical University, M. Sklodowskiej-Curie 52, 50-369 Wroclaw, Poland.
Oleszkiewicz P; Department of Radiology and Imaging Diagnostics II, Lower Silesian Center of Oncology, Pulmonology and Hematology, Grabiszynska 105, 53-439 Wroclaw, Poland.
Dzimira S; Department of Pathology, Wroclaw University of Environmental and Life Sciences, C. K. Norwida 31, 50-375 Wroclaw, Poland.
Kucharska AZ; Department of Fruit, Vegetable, and Plant Nutraceutical Technology, Wroclaw University of Environmental and Life Sciences, J. Chelmonskiego 37, 51-630 Wroclaw, Poland.
Słupski W; Department of Pharmacology, Wroclaw Medical University, J. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.
Matuszewska A; Department of Pharmacology, Wroclaw Medical University, J. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.
Nowak B; Department of Pharmacology, Wroclaw Medical University, J. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.
Szeląg A; Department of Pharmacology, Wroclaw Medical University, J. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland.
Piórecki N; Bolestraszyce Arboretum and Institute of Physiography, Bolestraszyce 130, 37-722 Wyszatyce, Poland.; Institute of Physical Culture Sciences, Medical College, University of Rzeszow, Cicha 2A, 35-326 Rzeszow, Poland.
Zaleska-Dorobisz U; Department of General and Pediatric Radiology, Wroclaw Medical University, M. Sklodowskiej-Curie 50/52, 50-369 Wroclaw, Poland.
Sozański T; Department of Preclinical Sciences, Pharmacology and Medical Diagnostics, Faculty of Medicine, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 18; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Cornus*/chemistry
Lagomorpha*
Plant Extracts*/pharmacology
Animals ; Rabbits ; Anthocyanins ; ATP-Binding Cassette Transporters ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; Diet ; Fruit/chemistry ; Liver ; Liver X Receptors/genetics ; PPAR alpha/genetics ; PPAR gamma/genetics ; Sterol Regulatory Element Binding Protein 1/genetics
Czasopismo naukowe
Tytuł:
Role of Brain Liver X Receptor in Parkinson's Disease: Hidden Treasure and Emerging Opportunities.
Autorzy:
Alnaaim SA; Clinical Neurosciences Department, College of Medicine, King Faisal University, Hofuf, Saudi Arabia.
Al-Kuraishy HM; Department of Clinical Pharmacology and Therapeutic Medicine, College of Medicine, ALmustansiriyiah University, Baghdad, 14132, Iraq.
Alexiou A; Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW, 2770, Australia.; AFNP Med, 1030, Wien, Austria.
Papadakis M; Department of Surgery II, University Hospital Witten-Herdecke, Heusnerstrasse 40, University of Witten-Herdecke, 42283, Wuppertal, Germany. marios_.
Saad HM; Department of Pathology, Faculty of Veterinary Medicine, Matrouh University, Marsa Matruh, 51744, Egypt.
Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, AlBeheira, 22511, Egypt.
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Źródło:
Molecular neurobiology [Mol Neurobiol] 2024 Jan; Vol. 61 (1), pp. 341-357. Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*/pathology
Neurodegenerative Diseases*/metabolism
Humans ; Liver X Receptors/metabolism ; Neuroinflammatory Diseases ; Brain/metabolism ; Dopaminergic Neurons/metabolism ; Cholesterol/metabolism
Czasopismo naukowe
Tytuł:
Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage.
Autorzy:
Fan L; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Jin L; MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Tang T; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Zheng Y; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Chen Z; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Lin H; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Ding C; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Wang T; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Chen H; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Guo Y; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Xu C; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Zhou H; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Wu X; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Fu X; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Yan F; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
Mao Z; MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Chen G; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310016, China.; Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases, Hangzhou, 310016, China.
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Źródło:
Theranostics [Theranostics] 2024 Jan 01; Vol. 14 (1), pp. 283-303. Date of Electronic Publication: 2024 Jan 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neutrophils*
Nanoparticles*
Mice ; Animals ; Humans ; Desmosterol ; Mice, Inbred C57BL ; Cerebral Hemorrhage/drug therapy ; Liver X Receptors ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł:
Hydroxylation site-specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR.
Autorzy:
Saito H; Laboratory of Food Biochemistry, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Tachiura W; Laboratory of Food Biochemistry, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Nishimura M; Laboratory of Food Biochemistry, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Shimizu M; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Sato R; Laboratory of Food Biochemistry, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan.
Yamauchi Y; Laboratory of Food Biochemistry, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Jan; Vol. 299 (1), pp. 102733. Date of Electronic Publication: 2022 Nov 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol*/metabolism
Liver X Receptors*/metabolism
Oxysterols*/metabolism
Sterol Regulatory Element Binding Protein 2*/metabolism
Animals ; Cricetinae ; Mice ; Rats ; CHO Cells ; Cholesterol 24-Hydroxylase ; Cricetulus ; Homeostasis ; Hydroxylation ; Proteins/metabolism
Czasopismo naukowe
Tytuł:
Liver X receptor activation mitigates oxysterol-induced dysfunction in fetoplacental endothelial cells.
Autorzy:
George M; Department of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria. Electronic address: .
Allerkamp HH; Department of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria.
Koshenov Z; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010 Graz, Austria; Department of Biochemistry, Weill Cornell Medicine, New York, USA.
Oflaz FE; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010 Graz, Austria.
Tam-Amersdorfer C; Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Immunology, Medical University of Graz, 8010 Graz, Austria.
Kolesnik T; Center for Medical Research, Medial University of Graz, Austria.
Rittchen S; Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Immunology, Medical University of Graz, 8010 Graz, Austria; Department of Pharmacology, Medical University of Graz, Austria.
Lang M; Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Immunology, Medical University of Graz, 8010 Graz, Austria.
Fröhlich E; Center for Medical Research, Medial University of Graz, Austria.
Graier W; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University of Graz, 8010 Graz, Austria.
Strobl H; Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Immunology, Medical University of Graz, 8010 Graz, Austria.
Wadsack C; Department of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria; BioTech-Med, 8010 Graz, Austria. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2024 Apr; Vol. 1869 (3), pp. 159466. Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Oxysterols*/metabolism
Pregnancy ; Female ; Humans ; Placenta/metabolism ; Liver X Receptors/metabolism ; Endothelial Cells/metabolism ; Reactive Oxygen Species/metabolism ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
CYP27A1 inhibits proliferation and migration of clear cell renal cell carcinoma via activation of LXRs/ABCA1.
Autorzy:
Liang Z; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Jiao W; Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Wang L; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chen Y; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Li D; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhang Z; Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhang Z; Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Liang Y; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. Electronic address: .
Niu H; Key Laboratory, Department of Urology and Andrology, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China; Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. Electronic address: .
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Źródło:
Experimental cell research [Exp Cell Res] 2022 Oct 01; Vol. 419 (1), pp. 113279. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP Binding Cassette Transporter 1*/metabolism
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/metabolism
Cholestanetriol 26-Monooxygenase*/metabolism
Kidney Neoplasms*
Liver X Receptors*/metabolism
Cell Proliferation ; Cholesterol ; Humans
Czasopismo naukowe
Tytuł:
Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages.
Autorzy:
Zhang R; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Dong Y; Department of Biochemistry, Microbiology, & Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Liu Y; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
Moezzi D; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Ghorbani S; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Mirzaei R; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Lozinski BM; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Dunn JF; Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Yong VW; Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada .
Xue M; Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China .; Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China.
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Źródło:
Stroke and vascular neurology [Stroke Vasc Neurol] 2023 Dec 29; Vol. 8 (6), pp. 486-502. Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Microglia*/metabolism
Brain Injuries*/metabolism
Mice ; Animals ; Liver X Receptors/agonists ; Liver X Receptors/metabolism ; Orphan Nuclear Receptors/agonists ; Orphan Nuclear Receptors/metabolism ; Diffusion Tensor Imaging ; Macrophages/metabolism ; Cholesterol/metabolism ; Cholesterol/pharmacology ; Cerebral Hemorrhage/metabolism ; Inflammation ; Hematoma
Czasopismo naukowe
Tytuł:
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Autorzy:
Vacondio D; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Nogueira Pinto H; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Coenen L; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Biomedical Primate Research Centre, Department of Neurobiology and Aging, Rijswijk, the Netherlands.
Mulder IA; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam UMC location University of Amsterdam, Department of Biomedical Engineering and Physics, Meibergdreef 9, Amsterdam, the Netherlands.
Fontijn R; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
van Het Hof B; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Fung WK; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Jongejan A; Amsterdam UMC location University of Amsterdam, Epidemiology and Data Science, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Public Health, Methodology, Amsterdam, The Netherlands.; Amsterdam Infection and Immunity, Inflammatory Diseases, Amsterdam, The Netherlands.
Kooij G; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Zelcer N; Amsterdam UMC location University of Amsterdam Department of Medical Biochemistry, Meibergdreef 9, Amsterdam, the Netherlands.; Amsterdam UMC location University of Amsterdam, Cardiovascular Sciences and Gastroenterology and Metabolism, Meibergdreef 9, Amsterdam, the Netherlands.
Rozemuller AJ; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Pathology, De Boelelaan 1117, Amsterdam, the Netherlands.
de Vries HE; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.
de Wit NM; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, De Boelelaan 1108, Amsterdam, the Netherlands. .; Amsterdam Neuroscience, Amsterdam, the Netherlands. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Nov 28; Vol. 14 (11), pp. 781. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/metabolism
Cerebral Amyloid Angiopathy*/complications
Cerebral Amyloid Angiopathy*/metabolism
Cerebral Amyloid Angiopathy*/pathology
Humans ; Amyloid beta-Peptides/metabolism ; Blood-Brain Barrier/metabolism ; Endothelial Cells/metabolism ; Hypoxia/metabolism ; Liver X Receptors/genetics ; Liver X Receptors/metabolism ; Snail Family Transcription Factors/genetics ; Snail Family Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
LXR activation ameliorates high glucose stress-induced aberrant mitochondrial dynamics via downregulation of Calpain1 expression in H9c2 cardiomyoblasts.
Autorzy:
Lin J; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Wang F; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Jiang G; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Zhang T; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
Zhang J; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.
He Q; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. Electronic address: .
Fan Y; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jul 23; Vol. 614, pp. 145-152. Date of Electronic Publication: 2022 May 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calpain*/genetics
Calpain*/metabolism
Diabetes Mellitus, Experimental*/metabolism
Diabetic Cardiomyopathies*/metabolism
Glucose*/metabolism
Liver X Receptors*/genetics
Liver X Receptors*/metabolism
Mitochondrial Dynamics*/genetics
Mitochondrial Dynamics*/physiology
Animals ; Apoptosis ; Down-Regulation ; Myocytes, Cardiac/metabolism ; Oxidative Stress ; Rats
Czasopismo naukowe
Tytuł:
Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407.
Autorzy:
Han W; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China.; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China.
Zhang D; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China.; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China.
Zhang P; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China.
Tao Q; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China.; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China.
Du X; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China.; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China.; Department of Pharmacy, Inner Mongolia Medical College, Hohhot, 010110, China.
Yu C; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China. .
Dong P; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China. .; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China. .
Zhu Y; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, 301617, China. .; Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biomedicine, 220 Dongting Road, TEDA, Tianjin, 300457, China. .
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Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Dec 08; Vol. 23 (1), pp. 445. Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophages*
Hyperlipidemias*/drug therapy
Male ; Mice ; Animals ; Cholesterol/metabolism ; Liver X Receptors/metabolism ; Ethanol
Czasopismo naukowe

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