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Wyszukujesz frazę ""Liver-Specific Organic Anion Transporter 1"" wg kryterium: Temat


Tytuł :
Genetic Factors and Delayed TSB Monitoring and Treatment as Risk Factors Associated with Severe Hyperbilirubinemia in Term Neonates Admitted for Phototherapy.
Autorzy :
Boo NY; Department of Population Medicine, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Bandar Sungai Long, Selangor, Malaysia.
Sin S; Department of Pre-Clinical Science, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Bandar Sungai Long, Selangor, Malaysia.
Chee SC; Department of Pediatrics, Selayang Hospital, Selayang, Selangor, Malaysia.
Mohamed M; Department of Pediatrics, Selayang Hospital, Selayang, Selangor, Malaysia.
Ahluwalia AK; Department of Pediatrics, Selayang Hospital, Selayang, Selangor, Malaysia.
Ling MM; Department of Pediatrics, Selayang Hospital, Selayang, Selangor, Malaysia.
Ong HK; Department of Pre-Clinical Science, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Bandar Sungai Long, Selangor, Malaysia.
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Źródło :
Journal of tropical pediatrics [J Trop Pediatr] 2020 Dec 01; Vol. 66 (6), pp. 569-582.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Bilirubin/*blood
Glucosephosphate Dehydrogenase/*genetics
Glucuronosyltransferase/*genetics
Hyperbilirubinemia, Neonatal/*genetics
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*genetics
Amplified Fragment Length Polymorphism Analysis ; Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Glucosephosphate Dehydrogenase/metabolism ; Glucuronosyltransferase/metabolism ; Humans ; Hyperbilirubinemia, Neonatal/diagnosis ; Hyperbilirubinemia, Neonatal/therapy ; Infant, Newborn ; Jaundice ; Liver-Specific Organic Anion Transporter 1/metabolism ; Male ; Phototherapy
Czasopismo naukowe
Tytuł :
Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.
Autorzy :
Li CY; Department of Pharmaceutics, University of Washington, Seattle, Washington (C.Y.L.); Amgen Research, Department of Pharmacokinetics and Drug Metabolism, Cambridge, Massachusetts (A.G.); SOLVO Biotechnology, Budapest, Hungary (Z.G., E.K.); Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington (B.P.).
Gupta A; Department of Pharmaceutics, University of Washington, Seattle, Washington (C.Y.L.); Amgen Research, Department of Pharmacokinetics and Drug Metabolism, Cambridge, Massachusetts (A.G.); SOLVO Biotechnology, Budapest, Hungary (Z.G., E.K.); Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington (B.P.).
Gáborik Z; Department of Pharmaceutics, University of Washington, Seattle, Washington (C.Y.L.); Amgen Research, Department of Pharmacokinetics and Drug Metabolism, Cambridge, Massachusetts (A.G.); SOLVO Biotechnology, Budapest, Hungary (Z.G., E.K.); Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington (B.P.).
Kis E; Department of Pharmaceutics, University of Washington, Seattle, Washington (C.Y.L.); Amgen Research, Department of Pharmacokinetics and Drug Metabolism, Cambridge, Massachusetts (A.G.); SOLVO Biotechnology, Budapest, Hungary (Z.G., E.K.); Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington (B.P.).
Prasad B; Department of Pharmaceutics, University of Washington, Seattle, Washington (C.Y.L.); Amgen Research, Department of Pharmacokinetics and Drug Metabolism, Cambridge, Massachusetts (A.G.); SOLVO Biotechnology, Budapest, Hungary (Z.G., E.K.); Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington (B.P.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Sep; Vol. 98 (3), pp. 234-242. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucuronides/*chemistry
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Organic Anion Transporters/*metabolism
Solute Carrier Organic Anion Transporter Family Member 1B3/*metabolism
Androgens/chemistry ; Biological Transport ; Cell Line ; HEK293 Cells ; Humans ; Liver-Specific Organic Anion Transporter 1/genetics ; Organic Anion Transporters/genetics ; Proteomics/methods ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics
Czasopismo naukowe
Tytuł :
Increased plasma concentrations of an antidyslipidemic drug pemafibrate co-administered with rifampicin or cyclosporine A in cynomolgus monkeys genotyped for the organic anion transporting polypeptide 1B1.
Autorzy :
Ogawa SI; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan; Tokyo New Drug Research Laboratories, Kowa Co., Ltd., Higashimurayama, Tokyo, 189-0022, Japan.
Shimizu M; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan.
Kamiya Y; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan.
Uehara S; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan; Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki, 210-0821, Japan.
Suemizu H; Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki, 210-0821, Japan.
Yamazaki H; Showa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan. Electronic address: .
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Źródło :
Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Aug; Vol. 35 (4), pp. 354-360. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Benzoxazoles/*blood
Butyrates/*blood
Cyclosporine/*blood
Hypolipidemic Agents/*blood
Liver-Specific Organic Anion Transporter 1/*genetics
Rifampin/*blood
Animals ; Benzoxazoles/administration & dosage ; Benzoxazoles/metabolism ; Butyrates/administration & dosage ; Butyrates/metabolism ; Caco-2 Cells ; Cyclosporine/administration & dosage ; Cyclosporine/metabolism ; Genotype ; Humans ; Hypolipidemic Agents/administration & dosage ; Hypolipidemic Agents/metabolism ; Injections, Intravenous ; Liver-Specific Organic Anion Transporter 1/metabolism ; Macaca fascicularis ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Rifampin/administration & dosage ; Rifampin/metabolism
Czasopismo naukowe
Tytuł :
[Analysis of genetic variants in a case with Rotor syndrome].
Autorzy :
Wang D; Department of Pediatrics, Jinhua Central Hospital, Jinhua, Zhejiang 321000, China. .
Li X
Lai P
Zheng L
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Źródło :
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2021 Apr 10; Vol. 38 (4), pp. 359-362.
Typ publikacji :
Journal Article
MeSH Terms :
Hyperbilirubinemia, Hereditary*
Exons/genetics ; Homozygote ; Humans ; Introns/genetics ; Liver-Specific Organic Anion Transporter 1 ; Male ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects.
Autorzy :
Fan X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Bai J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Hu M; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Xu Y; School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, China.
Zhao S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Sun Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Wang B; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Hu J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. Electronic address: .
Li Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Drug Metabolism, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
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Źródło :
Toxicology [Toxicology] 2020 May 15; Vol. 437, pp. 152445. Date of Electronic Publication: 2020 Apr 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemical and Drug Induced Liver Injury/*prevention & control
Flavonoids/*pharmacology
Liver/*drug effects
Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors
Organic Anion Transporters/*antagonists & inhibitors
Animals ; Bosentan ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Disease Models, Animal ; Flavonoids/chemistry ; Food-Drug Interactions ; HEK293 Cells ; Herb-Drug Interactions ; Humans ; Liver/metabolism ; Liver/pathology ; Liver-Specific Organic Anion Transporter 1/metabolism ; Male ; Methotrexate ; Molecular Conformation ; Organic Anion Transporters/metabolism ; Rats, Sprague-Dawley ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Physiologically Based Precision Dosing Approach for Drug-Drug-Gene Interactions: A Simvastatin Network Analysis.
Autorzy :
Wojtyniak JG; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
Selzer D; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
Schwab M; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; Departments of Clinical Pharmacology and Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.
Lehr T; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jan; Vol. 109 (1), pp. 201-211. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Interactions/*genetics
Simvastatin/*administration & dosage
ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Adult ; Computer Simulation ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 CYP3A/metabolism ; Humans ; Liver-Specific Organic Anion Transporter 1/genetics ; Liver-Specific Organic Anion Transporter 1/metabolism ; Male ; Models, Biological ; Polymorphism, Genetic/genetics ; Precision Medicine/methods ; Simvastatin/pharmacokinetics
Czasopismo naukowe
Tytuł :
Importance of OATP1B1 and 1B3 in the Liver Uptake of Luteolin and Its Consequent Glucuronidation Metabolites.
Autorzy :
Zhi H; College of Pharmaceutical Sciences , Soochow University , Suzhou 215123 , China.; Clinical Pharmacy Lab, Department of Pharmacy , The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University , Suzhou 215123 , China.
Yuan Y; Department of Pharmacy , The Affiliated Wuxi Matemity and Child Health Care Hospital of Nanjing Medical University , Wuxi 214000 , China.
Zhang C; College of Pharmaceutical Sciences , Soochow University , Suzhou 215123 , China.
Jiang Y; Clinical Pharmacy Lab, Department of Pharmacy , The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University , Suzhou 215123 , China.
Zhang H; Clinical Pharmacy Lab, Department of Pharmacy , The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University , Suzhou 215123 , China.
Wang C; Clinical Pharmacy Lab, Department of Pharmacy , The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University , Suzhou 215123 , China.
Ruan J; College of Pharmaceutical Sciences , Soochow University , Suzhou 215123 , China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Feb 19; Vol. 68 (7), pp. 2063-2070. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Luteolin/*metabolism
Solute Carrier Organic Anion Transporter Family Member 1B3/*metabolism
Biological Transport ; Glucuronosyltransferase/genetics ; Glucuronosyltransferase/metabolism ; Humans ; Liver-Specific Organic Anion Transporter 1/genetics ; Luteolin/chemistry ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics
Czasopismo naukowe
Tytuł :
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
Autorzy :
Liu J; Clinical Pharmacology Institute, Nanchang University, Nanchang, Jiangxi, 330031, China. .; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China. .
Guo Y; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China.
Liu K; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China.
Ye X; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China.
Wang F; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China.
Xu Y; School of Pharmacy, JiangXi Medical College, Shangrao, Jiangxi, 334000, China.
Xia C; Clinical Pharmacology Institute, Nanchang University, Nanchang, Jiangxi, 330031, China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 28; Vol. 10 (1), pp. 1308. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anions/*metabolism
Apigenin/*pharmacology
Glucuronates/*pharmacology
Hepatocytes/*drug effects
Hepatocytes/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Rosuvastatin Calcium/*metabolism
Animals ; Biomarkers ; Cell Line, Tumor ; Gene Expression ; Humans ; Liver/drug effects ; Liver/metabolism ; Liver-Specific Organic Anion Transporter 1/genetics ; Male ; Mass Spectrometry ; Rats ; Rosuvastatin Calcium/blood
Czasopismo naukowe
Tytuł :
Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma.
Autorzy :
Bowman CM; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Chen E; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Chen L; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Chen YC; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Liang X; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Wright M; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Chen Y; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California.
Mao J; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California .
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Źródło :
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2020 Jan; Vol. 48 (1), pp. 18-24. Date of Electronic Publication: 2019 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Proteins/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Solute Carrier Organic Anion Transporter Family Member 1B3/*metabolism
Cell Culture Techniques ; Culture Media ; HEK293 Cells ; Humans ; Liver-Specific Organic Anion Transporter 1/genetics ; Pravastatin/metabolism ; Protein Binding ; Quinolines/metabolism ; Rosuvastatin Calcium/metabolism ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Variability in In Vitro OATP1B1/1B3 Inhibition Data: Impact of Incubation Conditions on Variability and Subsequent Drug Interaction Predictions.
Autorzy :
McFeely SJ; Department of Pharmaceutics, UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.
Ritchie TK; Department of Pharmaceutics, UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.
Ragueneau-Majlessi I; Department of Pharmaceutics, UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.
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Źródło :
Clinical and translational science [Clin Transl Sci] 2020 Jan; Vol. 13 (1), pp. 47-52. Date of Electronic Publication: 2019 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Evaluation, Preclinical/*methods
Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors
Solute Carrier Organic Anion Transporter Family Member 1B3/*antagonists & inhibitors
Cell Culture Techniques/methods ; Cell Culture Techniques/standards ; Cyclosporine/pharmacology ; Datasets as Topic ; Drug Evaluation, Preclinical/standards ; Drug Interactions ; Gemfibrozil/pharmacology ; Guidelines as Topic ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Liver-Specific Organic Anion Transporter 1/metabolism ; Reproducibility of Results ; Rifampin/pharmacology ; Solute Carrier Organic Anion Transporter Family Member 1B3/metabolism ; United States ; United States Food and Drug Administration/standards
Czasopismo naukowe
Tytuł :
Effect of Hepatic Organic Anion-Transporting Polypeptide 1B Inhibition and Chronic Kidney Disease on the Pharmacokinetics of a Liver-Targeted Glucokinase Activator: A Model-Based Evaluation.
Autorzy :
Bergman A; Clinical Pharmacology, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut, USA.
Bi YA; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut, USA.
Mathialagan S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut, USA.
Litchfield J; Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts, USA.
Kazierad DJ; Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts, USA.
Pfefferkorn JA; Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts, USA.
Varma MVS; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2019 Oct; Vol. 106 (4), pp. 792-802. Date of Electronic Publication: 2019 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liver-Specific Organic Anion Transporter 1*/antagonists & inhibitors
Liver-Specific Organic Anion Transporter 1*/metabolism
Imidazoles/*pharmacokinetics
Kidney/*metabolism
Liver/*metabolism
Nicotinic Acids/*pharmacokinetics
Renal Insufficiency, Chronic/*metabolism
Area Under Curve ; Biological Transport ; Cyclosporine/pharmacokinetics ; Drug Interactions ; Enzyme Inhibitors/pharmacokinetics ; Glucokinase/metabolism ; HEK293 Cells ; Humans ; Hypoglycemia/chemically induced ; Hypoglycemia/prevention & control ; Membrane Transport Proteins/metabolism ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Impact of combinations of single-nucleotide polymorphisms of anthracycline transporter genes upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia.
Autorzy :
Megías-Vericat JE; Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain.; Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, Spain.
Martínez-Cuadrón D; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Herrero MJ; Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain.; Departamento Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.
Rodríguez-Veiga R; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Solana-Altabella A; Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, Spain.
Boluda B; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Ballesta-López O; Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, Spain.
Cano I; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Acuña-Cruz E; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Cervera J; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Poveda JL; Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, Spain.
Sanz M; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
Aliño SF; Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain.; Departamento Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.; Unidad de Farmacología Clínica, Área del Medicamento. Hospital Universitari I Politècnic, Valencia, Spain.
Montesinos P; Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain.; CIBERONC, Instituto Carlos III, Madrid, Spain.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2021 Mar; Vol. 62 (3), pp. 659-668. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Polymorphism, Single Nucleotide*
ATP-Binding Cassette Transporters/genetics ; Adult ; Anthracyclines/adverse effects ; Genotype ; Humans ; Induction Chemotherapy ; Liver-Specific Organic Anion Transporter 1/genetics ; Nucleotides/therapeutic use ; Prospective Studies
Czasopismo naukowe
Tytuł :
A model-based cost-effectiveness analysis of pharmacogenomic panel testing in cardiovascular disease management: preemptive, reactive, or none?
Autorzy :
Zhu Y; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.; Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Moriarty JP; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Swanson KM; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Takahashi PY; Division of Community Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Bielinski SJ; Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Weinshilboum R; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
Wang L; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
Borah BJ; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA. .; Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. .
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Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Mar; Vol. 23 (3), pp. 461-470. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmacogenetics*
Pharmacogenomic Testing*
Clopidogrel ; Cost-Benefit Analysis ; Humans ; Liver-Specific Organic Anion Transporter 1 ; Middle Aged ; Quality-Adjusted Life Years ; Vitamin K Epoxide Reductases
Czasopismo naukowe
Tytuł :
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment.
Autorzy :
Tatosian DA; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Yee KL; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Zhang Z; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Mostoller K; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Paul E; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Sutradhar S; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Larson P; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Chhibber A; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Wen J; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Wang YJ; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Lassman M; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Latham AH; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Pang J; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Crumley T; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Gillespie A; Data Management and Biometrics, Celerion, Lincoln, Nebraska, USA.
Marricco NC; Data Management and Biometrics, Celerion, Lincoln, Nebraska, USA.
Marenco T; Data Management and Biometrics, Celerion, Lincoln, Nebraska, USA.
Murphy M; Data Management and Biometrics, Celerion, Lincoln, Nebraska, USA.
Lasseter KC; Clinical Pharmacology of Miami, Inc, Miami, Florida, USA.
Marbury TC; Orlando Clinical Research Center, Orlando, Florida, USA.
Tweedie D; Merck & Co., Inc., Kenilworth, New Jersey, USA.; Currently Independent Consultant, Harleysville, Pennsylvania, USA.
Chu X; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Evers R; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Stoch SA; Merck & Co., Inc., Kenilworth, New Jersey, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Feb; Vol. 109 (2), pp. 403-415. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Interactions/*physiology
Kidney Diseases/*metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Area Under Curve ; Biomarkers/metabolism ; Healthy Volunteers ; Humans ; Liver-Specific Organic Anion Transporter 1/metabolism ; Midazolam/pharmacokinetics ; Rifampin/pharmacokinetics
Czasopismo naukowe
Tytuł :
Genetics of 35 blood and urine biomarkers in the UK Biobank.
Autorzy :
Sinnott-Armstrong N; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA. .; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland. .; VA Palo Alto Health Care System, Palo Alto, CA, USA. .
Tanigawa Y; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA. .
Amar D; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA.; Division of Cardiovascular Medicine and the Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA.
Mars N; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.
Benner C; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.
Aguirre M; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA.
Venkataraman GR; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA.
Wainberg M; Department of Computer Science, Stanford University, Stanford, CA, USA.
Ollila HM; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA.; Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Kiiskinen T; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland.
Havulinna AS; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare, Helsinki, Finland.
Pirruccello JP; Massachusetts General Hospital Division of Cardiology, Boston, MA, USA.; Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Qian J; Department of Statistics, Stanford University, Stanford, CA, USA.
Shcherbina A; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Division of Cardiovascular Medicine and the Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA.
Rodriguez F; Division of Cardiovascular Medicine and the Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA.
Assimes TL; VA Palo Alto Health Care System, Palo Alto, CA, USA.; Division of Cardiovascular Medicine and the Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA.
Agarwala V; Division of Cardiovascular Medicine and the Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA.
Tibshirani R; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA.; Department of Statistics, Stanford University, Stanford, CA, USA.
Hastie T; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA.; Department of Statistics, Stanford University, Stanford, CA, USA.
Ripatti S; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Public Health, Clinicum, University of Helsinki, Helsinki, Finland.
Pritchard JK; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA.
Daly MJ; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
Rivas MA; Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA. .
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Corporate Authors :
FinnGen
Źródło :
Nature genetics [Nat Genet] 2021 Feb; Vol. 53 (2), pp. 185-194. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biomarkers/*blood
Biomarkers/*urine
HLA Antigens/*genetics
Proteins/*genetics
Biological Specimen Banks ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/metabolism ; DNA Copy Number Variations ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Genetic Pleiotropy ; Humans ; Linkage Disequilibrium ; Liver-Specific Organic Anion Transporter 1/genetics ; Mendelian Randomization Analysis ; Polymorphism, Single Nucleotide ; Renal Insufficiency, Chronic ; Serine Endopeptidases/genetics ; United Kingdom
Czasopismo naukowe
Tytuł :
Rhabdomyolysis and acute kidney injury induced by the association of rosuvastatin and abiraterone: A case report and review of the literature.
Autorzy :
Ould-Nana I; Department of Intensive Care, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Cillis M; Department of Clinical Pharmacy, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Gizzi M; Department of Oncology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Gillion V; Department of Nephrology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Hantson P; Department of Intensive Care, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Gérard L; Department of Intensive Care, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
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Źródło :
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2021 Jan; Vol. 27 (1), pp. 216-219. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Abiraterone Acetate/*adverse effects
Acute Kidney Injury/*chemically induced
Rhabdomyolysis/*chemically induced
Rosuvastatin Calcium/*adverse effects
Aged ; Humans ; Liver-Specific Organic Anion Transporter 1/antagonists & inhibitors ; Male ; Prostatic Neoplasms, Castration-Resistant/drug therapy
Czasopismo naukowe
Tytuł :
Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.
Autorzy :
Zamek-Gliszczynski MJ; Drug Meabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Patel M; Pharmacokinetics and Drug Metabolism, Amgen Research, Cambridge, Massachusetts, USA.
Yang X; Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, Maryland, USA.
Lutz JD; Department of Clinical Pharmacology, Gilead Sciences, Inc, Foster City, California, USA.
Chu X; Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck & CO., Inc, Kenilworth, New Jersey, USA.
Brouwer KLR; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lai Y; Drug Metabolism, Gilead Sciences, Inc., Foster City, California, USA.
Lee CA; Nonclinical Development and Clinical Pharmacology, Arena Pharmaceuticals, San Diego, California, USA.
Neuhoff S; Simcyp Division, Certara UK Limited, Sheffield, UK.
Paine MF; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.
Sugiyama Y; Sugiyama Laboratory, RIKEN Baton Zone, Program, RIKEN Cluster for Science, RIKEN, Yokohama, Kanagawa, Japan.
Taskar KS; Drug Meabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK.
Galetin A; Centre for Applied Pharmacokinetic Research, School of Health Sciences, The University of Manchester, Manchester, UK.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jan; Vol. 109 (1), pp. 55-64. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism
Drug Development/*methods
Intestines/*physiology
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Biological Transport/physiology ; Hepatocytes/metabolism ; Humans ; Membrane Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.
Autorzy :
Türk D; Clinical Pharmacy, Saarland University, Campus C2 2, 66123, Saarbrücken, Germany.
Hanke N; Clinical Pharmacy, Saarland University, Campus C2 2, 66123, Saarbrücken, Germany.
Wolf S; Clinical Pharmacy, Saarland University, Campus C2 2, 66123, Saarbrücken, Germany.
Frechen S; Clinical Pharmacometrics, Bayer AG, Leverkusen, Germany.
Eissing T; Clinical Pharmacometrics, Bayer AG, Leverkusen, Germany.
Wendl T; Clinical Pharmacometrics, Bayer AG, Leverkusen, Germany.
Schwab M; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany.; Department of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.
Lehr T; Clinical Pharmacy, Saarland University, Campus C2 2, 66123, Saarbrücken, Germany. .
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Źródło :
Clinical pharmacokinetics [Clin Pharmacokinet] 2019 Dec; Vol. 58 (12), pp. 1595-1607.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Cytochrome P-450 CYP2C8/*drug effects
Liver-Specific Organic Anion Transporter 1/*drug effects
Area Under Curve ; Carbamates/administration & dosage ; Carbamates/pharmacokinetics ; Clarithromycin/administration & dosage ; Clarithromycin/pharmacokinetics ; Cytochrome P-450 CYP2C8/genetics ; Drug Interactions ; Gemfibrozil/administration & dosage ; Gemfibrozil/pharmacokinetics ; Humans ; Itraconazole/administration & dosage ; Itraconazole/pharmacokinetics ; Liver-Specific Organic Anion Transporter 1/genetics ; Pioglitazone/administration & dosage ; Pioglitazone/pharmacokinetics ; Piperidines/administration & dosage ; Piperidines/pharmacokinetics ; Rifampin/administration & dosage ; Rifampin/pharmacokinetics
Czasopismo naukowe
Tytuł :
Short-lasting inhibition of hepatic uptake transporter OATP1B1 by tyrosine kinase inhibitor pazopanib.
Autorzy :
Taguchi T; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., 14, Shinomiya, Minamigawara-cho, Yamashina-ku, Kyoto, 607-8042, Japan; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1102, Japan. Electronic address: .
Masuo Y; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1102, Japan. Electronic address: .
Sakai Y; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1102, Japan. Electronic address: .
Kato Y; Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1102, Japan. Electronic address: .
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Źródło :
Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2019 Dec; Vol. 34 (6), pp. 372-379. Date of Electronic Publication: 2019 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Pyrimidines/*pharmacology
Sulfonamides/*pharmacology
Biological Transport/drug effects ; Cells, Cultured ; HEK293 Cells ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Liver-Specific Organic Anion Transporter 1/metabolism
Czasopismo naukowe
Tytuł :
microRNA-206 modulates the hepatic expression of the organic anion-transporting polypeptide 1B1.
Autorzy :
El Saadany T; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
van Rosmalen B; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Gai Z; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.; Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Hiller C; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
Verheij J; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Stieger B; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
van Gulik T; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Visentin M; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
Kullak-Ublick GA; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.; Mechanistic Safety, CMO & Patient Safety, Global Drug Development, Novartis Pharma, Basel, Switzerland.
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Źródło :
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2019 Dec; Vol. 39 (12), pp. 2350-2359. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Estrone/*analogs & derivatives
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
MicroRNAs/*metabolism
Animals ; CHO Cells ; Cell Line, Tumor ; Computer Simulation ; Cricetulus ; Estrone/metabolism ; Female ; Humans ; Liver-Specific Organic Anion Transporter 1/genetics ; Male ; Middle Aged
Czasopismo naukowe

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