Various LncRNA Mechanisms in Gene Regulation Involving miRNAs or RNA-Binding Proteins in Non-Small-Cell Lung Cancer: Main Signaling Pathways and Networks.
Autorzy:
Braga EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.; Research Centre for Medical Genetics, 115522 Moscow, Russia. Fridman MV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Burdennyy AM; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. LoginovVI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.; Research Centre for Medical Genetics, 115522 Moscow, Russia. Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. Pronina IV; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Morozov SG; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs.
Autorzy:
Braga EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.; Research Centre for Medical Genetics, 115522 Moscow, Russia. Fridman MV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Burdennyy AM; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Filippova EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. LoginovVI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.; Research Centre for Medical Genetics, 115522 Moscow, Russia. Pronina IV; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. Kushlinskii NE; N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia.
Aberrant Methylation of 20 miRNA Genes Specifically Involved in Various Steps of Ovarian Carcinoma Spread: From Primary Tumors to Peritoneal Macroscopic Metastases.
Autorzy:
LoginovVI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Pronina IV; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Filippova EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Burdennyy AM; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Lukina SS; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Kazubskaya TP; N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia. Uroshlev LA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Fridman MV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Brovkina OI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Apanovich NV; Research Center for Medical Genetics, 115478 Moscow, Russia. Karpukhin AV; Research Center for Medical Genetics, 115478 Moscow, Russia. Stilidi IS; N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia. Kushlinskii NE; N.N. Blokhin National Medical Research Center of Oncology, 115478 Moscow, Russia. Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. Braga EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
LncRNAs in the Regulation of Genes and Signaling Pathways through miRNA-Mediated and Other Mechanisms in Clear Cell Renal Cell Carcinoma.
Autorzy:
Braga EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Fridman MV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Filippova EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. LoginovVI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Pronina IV; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Burdennyy AM; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Karpukhin AV; Research Centre for Medical Genetics, 115522 Moscow, Russia. Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. Morozov SG; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Long Noncoding RNA GAS5 in Breast Cancer: Epigenetic Mechanisms and Biological Functions.
Autorzy:
Filippova EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Fridman MV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991 Moscow, Russia. Burdennyy AM; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. LoginovVI; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Pronina IV; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Lukina SS; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia. Braga EA; Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Tumor Suppressor Function of the SEMA3B Gene in Human Lung and Renal Cancers.
Autorzy:
LoginovVI; Laboratory of Pathogenomics and Transcriptomics, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, 125315, Moscow, Russia; Laboratory of Molecular Genetics of Complex Inherited Diseases, Research Center of Medical Genetics, Russian Academy of Medical Sciences, 115478, Moscow, Russia. Dmitriev AA; Laboratory of Structural and Functional Genomics, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia; Department of Pathomorphology, P.A. Herzen Moscow Cancer Research Institute, Ministry of Healthcare of the Russian Federation, 125284, Moscow, Russia. Senchenko VN; Laboratory of Structural and Functional Genomics, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia. Pronina IV; Laboratory of Pathogenomics and Transcriptomics, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, 125315, Moscow, Russia; Laboratory of Molecular Genetics of Complex Inherited Diseases, Research Center of Medical Genetics, Russian Academy of Medical Sciences, 115478, Moscow, Russia. Khodyrev DS; Laboratory of Genetics, Federal Research Clinical Center of Federal Medical and Biological Agency of Russia, 115682, Moscow, Russia. Kudryavtseva AV; Laboratory of Structural and Functional Genomics, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia; Department of Pathomorphology, P.A. Herzen Moscow Cancer Research Institute, Ministry of Healthcare of the Russian Federation, 125284, Moscow, Russia. Krasnov GS; Laboratory of Structural and Functional Genomics, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia; Laboratory of Biotechnology, Mechnikov Research Institute for Vaccines and Sera, Russian Academy of Medical Sciences, 105064, Moscow, Russia. Gerashchenko GV; Department of Molecular Oncogenetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 03680, Kiev, Ukraine. Chashchina LI; Department of Molecular Oncogenetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 03680, Kiev, Ukraine. Kazubskaya TP; Research Institute of Clinical Oncology, N.N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, 115478, Moscow, Russia. Kondratieva TT; Research Institute of Clinical Oncology, N.N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, 115478, Moscow, Russia. Lerman MI; Scientific Board, Affina Biotechnologies, 06902, Stamford, CT, USA. Angeloni D; The Institute of Life Sciences, Scuola Superiore Sant'Anna, 56127, Pisa, Italy; Institute of Clinical Physiology, National Research Council, 56124, Pisa, Italy; Istituto Toscano Tumori, 56124, Pisa, Italy. Braga EA; Laboratory of Pathogenomics and Transcriptomics, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, 125315, Moscow, Russia; Laboratory of Molecular Genetics of Complex Inherited Diseases, Research Center of Medical Genetics, Russian Academy of Medical Sciences, 115478, Moscow, Russia; Laboratory of Post Genomic Molecular Genetic Research, Institute of Biochemical Physics, Russian Academy of Sciences, 119334, Moscow, Russia. Kashuba VI; Department of Molecular Oncogenetics, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 03680, Kiev, Ukraine; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, SE-17177, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2015 May 11; Vol. 10 (5), pp. e0123369. Date of Electronic Publication: 2015 May 11 (Print Publication: 2015).
Upregulation of RHOA and NKIRAS1 genes in lung tumors is associated with loss of their methylation as well as with methylation of regulatory miRNA genes.
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