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Wyświetlanie 1-20 z 22
Podgląd okładki
Tytuł :
Cross-species functional modules link proteostasis to human normal aging
Autorzy :
Komljenovic, Andrea
Li, Hao
Sorrentino, Vincenzo
Kutalik, Zoltán
Auwerx, Johan
Robinson-Rechavi, Marc
Pokaż więcej
Temat :
Research Article
Biology and Life Sciences
Developmental Biology
Organism Development
Aging
Physiology
Physiological Processes
Medicine and Health Sciences
Anatomy
Musculoskeletal System
Muscles
Skeletal Muscles
Brain
Hippocampus
Genetics
Gene Expression
Gene Identification and Analysis
Genetic Networks
Computer and Information Sciences
Network Analysis
Evolutionary Biology
Evolutionary Genetics
Computational Biology
Genome Analysis
Genome-Wide Association Studies
Genomics
Human Genetics
Gene Ontologies
Adult
Aged
Aging/genetics
Aging/metabolism
Animals
Caenorhabditis elegans
Caloric Restriction
Drosophila melanogaster
Evolution, Molecular
Female
Gene Expression Profiling
Genetic Markers
Humans
Longevity/genetics
Longevity/physiology
Male
Mice
Middle Aged
Models, Biological
Proteostasis/genetics
Species Specificity
Young Adult
Systems biology
Genetic association
Proteostasis
Conserved sequence
Computational biology
Biology
Gene
Genome-wide association study
Model organism
ved/biology.organism_classification_rank.species
ved/biology
Trait
Computational Theory and Mathematics
Cellular and Molecular Neuroscience
Molecular Biology
Ecology
Modelling and Simulation
Ecology, Evolution, Behavior and Systematics
Human evolutionary genetics
biology.organism_classification
Gene expression profiling
Biology (General)
QH301-705.5
Źródło :
PLoS Computational Biology
PLoS computational biology, vol. 15, no. 7, pp. e1007162
PLoS Computational Biology, Vol 15, Iss 7, p e1007162 (2019)
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c9d30005a9a83fd8128230032b447b
http://europepmc.org/articles/PMC6634426
Szczegóły
Podgląd okładki
Tytuł :
A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity
Autorzy :
Megan M. Marron
Iva Miljkovic
Robert M. Boudreau
Kaare Christensen
Mary F. Feitosa
Joseph H. Lee
Paola Sebastiani
Bharat Thyagarajan
Mary K. Wojczynski
Joseph M. Zmuda
Anne B. Newman
Pokaż więcej
Temat :
Cognition
Healthy aging
Longevity
Metabolism
Phenotype
Lung/physiology
Metabolism/physiology
Humans
Family Health
Longevity/physiology
Healthy Aging/metabolism
Article
Endocrinology
Endocrinology, Diabetes and Metabolism
media_common.quotation_subject
media_common
medicine.medical_specialty
medicine
Offspring
Internal medicine
Cohort
Biology
Body mass index
Physiology
Insulin
medicine.medical_treatment
Proband
Allele
Źródło :
Marron, M M, Miljkovic, I, Boudreau, R M, Christensen, K, Feitosa, M F, Lee, J H, Sebastiani, P, Thyagarajan, B, Wojczynski, M K, Zmuda, J M, Newman, A B & Long Life Family Study 2019, ' A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity ', Metabolism: Clinical and Experimental, vol. 94, pp. 28-38 . https://doi.org/10.1016/j.metabol.2019.01.010
Metabolism
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816960f26dd60eb3dfec654d360c44d5
https://findresearcher.sdu.dk:8443/ws/files/146455969/A_novel_healthy_metabolic_phenotype_developed_among_a_cohort_of_families_enriched_for_longevity.pdf
Szczegóły
Podgląd okładki
Tytuł :
Assessment of health status by molecular measures in adults ranging from middle-aged to old
Autorzy :
Waaijer, M.E.C.
Westendorp, R.G.J.
Goldeck, D.
Gunn, D.A.
Pawelec, G.
Stijntjes, M.
Slagboom, E.P.
Maier, A. B.
Pokaż więcej
Temat :
Adult
Aged
80 and over
Biomarkers/analysis
C-Reactive Protein/analysis
Female
Geriatric Assessment/methods
Hand Strength/physiology
Health Status
Humans
Immunosenescence
Linear Models
Longevity/physiology
Male
Middle Aged
Multivariate Analysis
Stroop Test
Tumor Suppressor Protein p14ARF/analysis
Walk Test
Biochemistry
Ageing
Molecular Biology
Genetics
Endocrinology
Cell Biology
Źródło :
Experimental Gerontology. 87:175-181
Dostępność :
https://explore.openaire.eu/search/publication?articleId=dris___00893::9545759ca9d00f271d6130df19302183
http://www.scopus.com/inward/record.url?scp=84964330286&partnerID=8YFLogxK
Szczegóły
Podgląd okładki
Tytuł :
Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span
Autorzy :
Biana Shtaif
Galit Pinto
Manfredo Quadroni
Andrija Finka
Pierre Goloubinoff
Galia Gat-Yablonski
Pokaż więcej
Temat :
Cell Biology
Ageing
Proteostasis
Internal medicine
medicine.medical_specialty
medicine
Endocrinology
Chronic stress
Hsp90
biology.protein
biology
Biochemistry
Heat shock protein
Hsp70
Quantitative proteomics
Mitochondrion
Homeostasis
Research Paper
heat shock proteins
catch up growth
food restriction
aging
mitochondria
Aging/metabolism
Animals
Eating/physiology
Feeding Behavior/physiology
Food Deprivation
HSP70 Heat-Shock Proteins/metabolism
HSP90 Heat-Shock Proteins/metabolism
Homeostasis/physiology
Liver/metabolism
Longevity/physiology
Proteomics
Rats
Źródło :
Aging (Albany NY)
Aging, vol. 8, no. 8, pp. 1735-1758
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df9a55530d9c93b073185688750f859
https://www.aging-us.com/lookup/doi/10.18632/aging.101009
Szczegóły
Podgląd okładki
Tytuł :
Physiological increase of yolk testosterone level does not affect oxidative status and telomere length in gull hatchlings
Autorzy :
Parolini, Marco
Possenti, Cristina Daniela
Romano, Andrea
Caprioli, Manuela
Rubolini, Diego
Saino, Nicola
Pokaż więcej
Temat :
Multidisciplinary
Yolk
food.ingredient
food
Endocrinology
medicine.medical_specialty
medicine
Testosterone
Biology
Offspring
Internal medicine
Hatching
Androgen
medicine.drug_class
Oxidative stress
medicine.disease_cause
Hatchling
Telomere
Research Article
Biology and Life Sciences
Biochemistry
Hormones
Androgens
Lipid Hormones
Cell Biology
Chromosome Biology
Chromosomes
Chromosome Structure and Function
Telomeres
Telomere Length
Antioxidants
Oxidative Stress
Organisms
Eukaryota
Animals
Vertebrates
Amniotes
Birds
Seabirds
Gulls
Physiology
Reproductive Physiology
Oviposition
Clutches
Medicine and Health Sciences
Charadriiformes
Egg Yolk
Embryo, Nonmammalian
Longevity
Oxidation-Reduction
Reactive Oxygen Species
Biochemistry, Genetics and Molecular Biology (all)
Agricultural and Biological Sciences (all)
Settore BIO/07 - Ecologia
Androgens/metabolism
Antioxidants/metabolism
Charadriiformes/metabolism
Charadriiformes/physiology
Egg Yolk/metabolism
Embryo, Nonmammalian/metabolism
Longevity/physiology
Oxidative Stress/physiology
Reactive Oxygen Species/metabolism
Telomere/metabolism
Testosterone/metabolism
lcsh:Medicine
lcsh:R
lcsh:Science
lcsh:Q
embryonic structures
Źródło :
PLoS ONE
PloS one, vol. 13, no. 10, pp. e0206503
PLoS ONE, Vol 13, Iss 10, p e0206503 (2018)
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ce73b3211e2257e11ecdf47da9322f
Szczegóły
Podgląd okładki
Tytuł :
Diet has independent effects on the pace and shape of aging in Drosophila melanogaster
Autorzy :
Ruth Archer, C.
Basellini, Ugofilippo
Hunt, John
Simpson, Stephen J.
Lee, Kwang Pum
Baudisch, Annette
Pokaż więcej
Temat :
Geriatrics and Gerontology
Gerontology
Ageing
Geriatrics gerontology
Demography
Drosophila melanogaster
biology.organism_classification
biology
Single measure
Pace
Protein intake
Ecology
Research Article
Dietary restriction
Fruit flies
Geometric framework of nutrition
Gompertz
Shape
Dietary Proteins/analysis
Mortality
Feeding Behavior
Longevity/physiology
Aging/physiology
Animals
Animal Nutritional Physiological Phenomena
Diet
Life Expectancy
Models, Biological
Female
Dietary Carbohydrates/analysis
Nutritional Requirements/physiology
Źródło :
Biogerontology
Archer, C R, Basellini, U, Hunt, J, Simpson, S J, Lee, K P & Baudisch, A 2018, ' Diet has independent effects on the pace and shape of aging in Drosophila melanogaster ', Biogerontology, vol. 19, no. 1, pp. 1-12 . https://doi.org/10.1007/s10522-017-9729-1
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179d2c856b66db24fab990b627bbd371
Szczegóły
Podgląd okładki
Tytuł :
Demographics, Phenotypic Health Characteristics and Genetic Analysis of Centenarians in China
Autorzy :
Danan Gu
James W. Vaupel
Qiushi Feng
Yi Zeng
Pokaż więcej
Temat :
Article
Developmental Biology
Ageing
Longevity
media_common.quotation_subject
media_common
Socioeconomic status
Medicine
business.industry
business
Health indicator
Genome-wide association study
Centenarian
Population
education.field_of_study
education
Psychological resilience
Gerontology
Optimism
Adult
Aged
Aged, 80 and over
China
Cognition/physiology
Female
Gene-Environment Interaction
Genome-Wide Association Study
Health Status
Humans
Longevity/physiology
Male
Middle Aged
Population Dynamics
Self Report
Socioeconomic Factors
Źródło :
Zeng, Y, Feng, Q, Gu, D & Vaupel, J W 2017, ' Demographics, phenotypic health characteristics and genetic analysis of centenarians in China ', Mechanisms of Ageing and Development, vol. 165, no. Pt B, pp. 86-97 . https://doi.org/10.1016/j.mad.2016.12.010
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29477938dcad3cb7eb9ae42d9d675fbc
https://europepmc.org/articles/PMC5489367/
Szczegóły
Podgląd okładki
Tytuł :
Diversity of ageing across the tree of life
Autorzy :
Jones, Owen R.
Scheuerlein, Alexander
Salguero-Gómez, Roberto
Camarda, Carlo Giovanni
Schaible, Ralf
Casper, Brenda B.
Dahlgren, Johan P.
Ehrlén, Johan
García, María B.
Menges, Eric S.
Quintana-Ascencio, Pedro F.
Caswell, Hal
Baudisch, Annette
Vaupel, James W.
Pokaż więcej
Temat :
FNWI top publication
Article
Aging/physiology
Animals
Biological Evolution
Chlorophyta
Fertility/physiology
Longevity/physiology
Phylogeny
Plants
Reproduction/physiology
Multidisciplinary
Tree of life
Biology
Longevity
media_common.quotation_subject
media_common
Taxon
Phenoptosis
Ageing
Fertility
Ecology
Zoology
Evolution of ageing
Invertebrate
Źródło :
Jones, O, Scheuerlein, A, Salguero-Gómez, R, Camarda, C G, Schaible, R, Casper, B B, Dahlgren, J P, Ehrlén, J, García, M B, Menges, E S, Quintana-Ascencio, P F, Caswell, H, Baudisch, A & Vaupel, J W 2014, ' Diversity of ageing across the tree of life ', Nature, vol. 505, pp. 169–173 . https://doi.org/10.1038/nature12789
Nature, 505, 169-173. Nature Publishing Group
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b340013f279b025e27fcd634881b20
Szczegóły
Podgląd okładki
Tytuł :
Longitudinal Changes in Leukocyte Telomere Length and Mortality in Humans
Autorzy :
Laila Bendix
Mikael Thinggaard
Allan Linneberg
Kirsten Avlund
Merete Osler
Steen Kølvraa
Mogens Fenger
Pokaż więcej
Temat :
Biomarkers
Longevity
DNA damage and repair
Epidemiology
Life Style
Age Factors
Humans
Middle Aged
Risk Factors
Longevity/physiology
Male
Alcohol Drinking
Socioeconomic Factors
Telomere Shortening/physiology
Adult
Female
Aged
Leukocytes/pathology
Health Status
Longitudinal Studies
Smoking
Geriatrics and Gerontology
Ageing
Causality
Lifestyle factors
Correlation and dependence
Telomere
Genetics
Longitudinal study
Alcohol consumption
Medicine
business.industry
business
medicine.medical_specialty
Regression toward the mean
Demography
Źródło :
Bendix, L, Thinggaard, M, Fenger, M, Kølvraa, S, Avlund, K, Linneberg, A R & Osler, M 2014, ' Longitudinal Changes in Leukocyte Telomere Length and Mortality in Humans ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 69 A, no. 2, pp. 231-239 . https://doi.org/10.1093/gerona/glt153
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d79a5e2765b8407676c53eeaa0fb942
https://portal.findresearcher.sdu.dk/da/publications/7652ed95-68ac-4d6a-9249-0346756b5ad2
Szczegóły
Podgląd okładki
Tytuł :
Social insects as a model to study the molecular basis of ageing
Autorzy :
Stephanie Jemielity
Laurent Keller
Pokaż więcej
Temat :
Cell Biology
Endocrinology
Genetics
Molecular Biology
Ageing
Biochemistry
Biology
Model organism
ved/biology.organism_classification_rank.species
ved/biology
Evolutionary biology
Gene
Free-radical theory of aging
Vitellogenin
biology.protein
Juvenile hormone
ANT
Experimental work
Ecology
Aging/genetics/*physiology Animals Antioxidants/physiology Ants/genetics/*physiology Bees/genetics/*physiology Female Gene Expression Regulation/physiology Juvenile Hormones/physiology Longevity/physiology Male *Models, Biological Telomere/physiology Vitellogenins/physiology
behavior and behavior mechanisms
Źródło :
Experimental Gerontology, vol. 41, no. 6, pp. 553-6
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5864456ef2e147f191840d50608ff3be
https://api.elsevier.com/content/article/PII:S0531556506001057?httpAccept=text/xml
Szczegóły
Podgląd okładki
Tytuł :
Familial longevity is marked by better cognitive performance at middle age
Autorzy :
Stijntjes, Marjon
de Craen, Anton J M
van Heemst, Diana
Meskers, Carel G M
van Buchem, Mark A
Westendorp, Rudi G J
Slagboom, P Eline
Maier, Andrea B
Pokaż więcej
Temat :
Aged
Cognition/physiology
Family
Female
Humans
Longevity/physiology
Male
Middle Aged
Netherlands
Siblings
Stroop Test
Źródło :
PLoS ONE. 8(3)
Dostępność :
https://explore.openaire.eu/search/publication?articleId=dris___00893::2bf5b0a4c4de4fe9c4efc0816a066b2d
Szczegóły
Podgląd okładki
Tytuł :
Familial longevity is marked by better cognitive performance at middle age: the Leiden Longevity Study
Autorzy :
P. Eline Slagboom
Carel G. M. Meskers
Andrea B. Maier
Rudi G. J. Westendorp
Marjon Stijntjes
Anton J. M. de Craen
Mark A. van Buchem
Diana van Heemst
Pokaż więcej
Temat :
Medicine
Science
Research Article
Biology
Anatomy and Physiology
Physiological Processes
Aging
Developmental Biology
Organism Development
Neuroscience
Cognitive Neuroscience
Cognition
Epidemiology
Biomarker Epidemiology
Epidemiology of Aging
Geriatrics
Neurology
Cognitive Neurology
Dementia
Aged
Cognition/physiology
Family
Female
Humans
Longevity/physiology
Male
Middle Aged
Netherlands
Siblings
Stroop Test
Multidisciplinary
Stroop effect
Effects of sleep deprivation on cognitive performance
Gerontology
Longevity
media_common.quotation_subject
media_common
Cognitive test
Demography
Offspring
Digit symbol substitution test
Middle age
Źródło :
PLoS ONE, Vol 8, Iss 3, p e57962 (2013)
PLoS ONE, 8(3)
PLoS ONE
PLoS ONE; Vol 8
PLoS ONE, 8(3). Public Library of Science
PLoS ONE, 8(3):e57962. Public Library of Science
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82bbf92983739c5188834d7bb6c74de
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23483953/?tool=EBI
Szczegóły
Podgląd okładki
Tytuł :
Comportement d'inactivité physique : une réponse adaptative inappropriée au maintien de la santé dans nos sociétés ?
Autorzy :
Sittarame, Frédéric
Golay, Alain
Pokaż więcej
Temat :
ddc:613
Adult
Caregivers
Health Behavior
Humans
Longevity/physiology
Motivation
Motor Activity/physiology
Public Health
Quality of Life
Sedentary Lifestyle
Źródło :
Revue médicale suisse, Vol. 9, No 379 (2013) pp. 679-83
Dostępność :
https://explore.openaire.eu/search/publication?articleId=od______1400::cf2c92af3d14b2a5f0e8fd9aaec86efa
https://archive-ouverte.unige.ch/unige:42971
Szczegóły
Podgląd okładki
Tytuł :
Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies
Autorzy :
Mirko Francesconi
Miriam Capri
Francesco Lescai
J. P. de Magalhaes
Aurelia Santoro
Alexey Zaikin
Silvana Valensin
Claudio Franceschi
Daniela Monti
Stefano Salvioli
Paolo Tieri
Elisa Cevenini
Gastone Castellani
Elena Bellavista
Michele Mishto
Pokaż więcej
Temat :
Age Factors
Aging, physiology
Drug Design
Humans
Longevity, physiology
Models, Biological
Systems Biology
Drug Discovery
Pharmacology
Genetics
Organism
Phenotype
Computational biology
Proteomics
Senescence
Biology
Longevity
media_common.quotation_subject
media_common
Genomics
Protein degradation
Systems biology
Źródło :
Cevenini, E, Bellavista, E, Tieri, P, Castellani, G, Lescai, F, Francesconi, M, Mishto, M, Santoro, A, Valensin, S, Salvioli, S, Capri, M, Zaikin, A, Monti, D, Magalh?es, J P D & Franceschi, C 2010, ' Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies. ', Current Pharmaceutical Design, bind 16, nr. 7, s. 802-813 .
ResearcherID
Opis pliku :
STAMPA
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feaabf64e0d671645689829796a569f
https://pure.au.dk/portal/da/publications/systems-biology-and-longevity-an-emerging-approach-to-identify-innovative-antiaging-targets-and-strategies(3d3b2b01-fcca-4548-a050-c57d41ae9f17).html
Szczegóły
Podgląd okładki
Tytuł :
Fecundity and survival in relation to resistance to oxidative stress in a free-living bird
Autorzy :
Phillippe Christe
Godefroy Devevey
Pierre Bize
Pat Monaghan
Blandine Doligez
Pokaż więcej
Temat :
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]
Animals
Fertility/physiology
Longevity/physiology
Oxidative Stress/physiology
Songbirds/physiology
Ecology, Evolution, Behavior and Systematics
Hatching
Paternal care
Oxidative stress
medicine.disease_cause
medicine
Seasonal breeder
Biology
Reactive oxygen species
chemistry.chemical_classification
chemistry
Incubation
Ecology
Fecundity
Life history theory
Źródło :
Ecology
Ecology, Ecological Society of America, 2008, 89(8), pp.2584-2593
Ecology, vol. 89, no. 9, pp. 2584-2593
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50210f3e8b049c0caa1c0382dc06ef4a
https://hal.archives-ouvertes.fr/hal-00428107
Szczegóły
Podgląd okładki
Tytuł :
What are the effects of maternal and pre-adult environments on ageing in humans, and are there lessons from animal models?
Autorzy :
Laurent Keller
Paul M. Brakefield
Kaare Christensen
Rudi G. J. Westendorp
Maria Antonietta Stazi
Beatrix Grubeck-Loebenstein
Jim Oeppen
Tim Cowen
Marc Tatar
Angeles Rodríguez-Peña
David Gems
Pokaż więcej
Temat :
Adaptation, Physiological Animals Caloric Restriction Environment *Evolution Humans Longevity/*physiology Models, Animal *Phenotype
Developmental Biology
Ageing
Model organism
ved/biology.organism_classification_rank.species
ved/biology
Evolutionary biology
Maternal effect
Senescence
Survivorship curve
Adaptive plasticity
Ecology
Biology
Life span
Phenotypic plasticity
Źródło :
Brakefield, P M, Gems, D, Cowen, T & Christensen, K 2005, ' What are the effects of maternal and pre-adult environments on ageing in humans, and are there lessons from animal models? ', Mechanisms of Ageing and Development, vol. 126, no. 3, pp. 431-438 . https://doi.org/10.1016/j.mad.2004.07.013
Mechanisms of Ageing and Development, vol. 126, no. 3, pp. 431-8
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3e06d580fd872a65cade634f31deb1
https://portal.findresearcher.sdu.dk/da/publications/51c30630-dde0-11db-9628-000ea68e967b
Szczegóły
Wyświetlanie 1-20 z 22

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