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    Wyświetlanie 1-19 z 19
    Tytuł:
    Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease.
    Autorzy:
    Millar PR; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA. .
    Gordon BA; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.
    Wisch JK; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Schultz SA; Department of Neurology, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
    Benzinger TL; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.
    Cruchaga C; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
    Hassenstab JJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Ibanez L; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.; NeuroGenomics & Informatics Center, Washington University in St. Louis, St. Louis, MO, USA.
    Karch C; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
    Llibre-Guerra JJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Morris JC; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Perrin RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Department of Pathology & Immunology, Washington University in St. Louis, St. Louis, MO, USA.
    Supnet-Bell C; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Xiong C; Department of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA.
    Allegri RF; Instituto Neurológico Fleni, Buenos Aires, Argentina.
    Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
    Chhatwal JP; Department of Neurology, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
    Chrem Mendez PA; Instituto Neurológico Fleni, Buenos Aires, Argentina.
    Day GS; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.
    Hofmann A; German Center for Neurodegenerative Diseases (DZNE), 72076, Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076, Tübingen, Germany.
    Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.
    Jucker M; German Center for Neurodegenerative Diseases (DZNE), 72076, Tübingen, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076, Tübingen, Germany.
    Lee JH; Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
    Levin J; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
    Lopera F; Universidad de Antioquia, Medellín, Colombia.
    Niimi Y; Unit for Early and Exploratory Clinical Development, The University of Tokyo Hospital, Bunkyo-Ku, Tokyo, Japan.
    Sánchez-González VJ; Departamento de Clínicas, CUALTOS, Universidad de Guadalajara, Tepatitlán de Morelos, Jalisco, México.
    Schofield PR; Neuroscience Research Australia, Sydney, NSW, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
    Sosa-Ortiz AL; Instituto Nacional de Neurologia y Neurocirugía MVS, CDMX, Ciudad de México, Mexico.
    Vöglein J; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany.
    Bateman RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
    Ances BM; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.
    McDade EM; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.
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    Corporate Authors:
    Dominantly Inherited Alzheimer Network
    Źródło:
    Molecular neurodegeneration [Mol Neurodegener] 2023 Dec 19; Vol. 18 (1), pp. 98. Date of Electronic Publication: 2023 Dec 19.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Alzheimer Disease*
    Humans ; Amyloid beta-Peptides/metabolism ; Brain/metabolism ; Amyloid ; Aging ; Biomarkers ; Positron-Emission Tomography ; tau Proteins/genetics ; tau Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology.
    Autorzy:
    Gomez-Sequeda N; Grupo de Neurociencias de Antioquia, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia (UdeA), Calle 70 No. 52-21, and Calle 62 # 52-59, Torre 1, Laboratorio 412, Medellín, Colombia.
    Mendivil-Perez M; Grupo de Neurociencias de Antioquia, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia (UdeA), Calle 70 No. 52-21, and Calle 62 # 52-59, Torre 1, Laboratorio 412, Medellín, Colombia.
    Jimenez-Del-Rio M; Grupo de Neurociencias de Antioquia, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia (UdeA), Calle 70 No. 52-21, and Calle 62 # 52-59, Torre 1, Laboratorio 412, Medellín, Colombia.
    Lopera F; Grupo de Neurociencias de Antioquia, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia (UdeA), Calle 70 No. 52-21, and Calle 62 # 52-59, Torre 1, Laboratorio 412, Medellín, Colombia.
    Velez-Pardo C; Grupo de Neurociencias de Antioquia, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia (UdeA), Calle 70 No. 52-21, and Calle 62 # 52-59, Torre 1, Laboratorio 412, Medellín, Colombia. .
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    Źródło:
    Scientific reports [Sci Rep] 2023 Aug 08; Vol. 13 (1), pp. 12833. Date of Electronic Publication: 2023 Aug 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/metabolism
    Humans ; Amyloid beta-Peptides/metabolism ; Presenilin-1/genetics ; Presenilin-1/metabolism ; Neurons/metabolism ; Cholinergic Agents ; Mutation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent.
    Autorzy:
    Mendivil-Perez M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), Calle 70 No. 52-21, Calle 62#52-59, Building 1, Room 412, SIU, Medellin 050010, Colombia.
    Velez-Pardo C; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), Calle 70 No. 52-21, Calle 62#52-59, Building 1, Room 412, SIU, Medellin 050010, Colombia.
    Lopera F; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), Calle 70 No. 52-21, Calle 62#52-59, Building 1, Room 412, SIU, Medellin 050010, Colombia.
    Kosik KS; Neuroscience Research Institute, Department of Molecular Cellular Developmental Biology, University of California, Santa Barbara, CA 93106, USA.
    Jimenez-Del-Rio M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), Calle 70 No. 52-21, Calle 62#52-59, Building 1, Room 412, SIU, Medellin 050010, Colombia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 May 18; Vol. 24 (10). Date of Electronic Publication: 2023 May 18.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Induced Pluripotent Stem Cells*/metabolism
    Alzheimer Disease*/metabolism
    Mesenchymal Stem Cells*/metabolism
    Humans ; Cholinergic Neurons/metabolism ; Cholinergic Agents/metabolism ; Presenilin-1/genetics ; Presenilin-1/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Analysis of family stigma and socioeconomic factors impact among caregivers of patients with early- and late-onset Alzheimer's disease and frontotemporal dementia.
    Autorzy:
    Velilla L; Neuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia. .; Global Brain Health Institute, Memory and Aging Center University of California San Francisco, 1651 4th St Suite 212, San Francisco, CA, 94143, USA. .
    Acosta-Baena N; Neuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia.
    Allen I; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
    Lopera F; Neuroscience Group of Antioquia, Medical School Antioquia University, Calle 62 N 52-59, 050010, Medellín, Antioquia, Colombia.
    Kramer J; Global Brain Health Institute, Memory and Aging Center University of California San Francisco, 1651 4th St Suite 212, San Francisco, CA, 94143, USA.
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    Źródło:
    Scientific reports [Sci Rep] 2022 Jul 25; Vol. 12 (1), pp. 12663. Date of Electronic Publication: 2022 Jul 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/genetics
    Frontotemporal Dementia*/psychology
    Caregivers/psychology ; Humans ; Late Onset Disorders ; Quality of Life/psychology ; Socioeconomic Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    White matter hyperintensities are a prominent feature of autosomal dominant Alzheimer's disease that emerge prior to dementia.
    Autorzy:
    Schoemaker D; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Zanon Zotin MC; J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
    Chen K; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Igwe KC; Taub Institute for Research On Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
    Vila-Castelar C; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Martinez J; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
    Baena A; Grupo Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Fox-Fuller JT; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
    Lopera F; Grupo Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Brickman AM; Taub Institute for Research On Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center and Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
    Quiroz YT; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. .; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, MB, Boston, USA. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2022 Jun 29; Vol. 14 (1), pp. 89. Date of Electronic Publication: 2022 Jun 29.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
    MeSH Terms:
    Alzheimer Disease*/diagnostic imaging
    Alzheimer Disease*/genetics
    White Matter*/diagnostic imaging
    White Matter*/pathology
    Adult ; Cross-Sectional Studies ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Positron-Emission Tomography ; Presenilin-1/genetics ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects.
    Autorzy:
    Acosta-Uribe J; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA.; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Aguillón D; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Cochran JN; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
    Giraldo M; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.; Instituto Neurológico de Colombia (INDEC), Medellín, Colombia.
    Madrigal L; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Killingsworth BW; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA.
    Singhal R; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA.
    Labib S; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA.
    Alzate D; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Velilla L; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Moreno S; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    García GP; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Saldarriaga A; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Piedrahita F; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Hincapié L; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    López HE; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Perumal N; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA.
    Morelo L; Department of Internal Medicine, School of Medicine, Universidad del Sinú, Montería, Colombia.
    Vallejo D; Department of Neurology, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Solano JM; Department of Neurology, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Surace EI; Laboratorio de Enfermedades Neurodegenerativas (Fleni-CONICET), Buenos Aires, Argentina.
    Itzcovich T; Laboratorio de Enfermedades Neurodegenerativas (Fleni-CONICET), Buenos Aires, Argentina.
    Allegri R; Centro de Memoria y Envejecimiento (Fleni-CONICET), Buenos Aires, Argentina.
    Sánchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic de Barcelona, IDIBAPS and University of Barcelona, Barcelona, Spain.
    Villegas-Lanau A; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia.
    White CL 3rd; Neuropathology Section, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
    Matallana D; Instituto de Envejecimiento, Department of Psychiatry, School of Medicine, Pontifical Xaverian University, Bogotá, Colombia.; Department of Mental Health, Hospital Universitario Santa Fe de Bogotá, Bogotá, Colombia.
    Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
    Browning SR; Department of Biostatistics, University of Washington, Seattle, WA, USA.
    Lopera F; Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Colombia. francisco.lopera@gna.org.co.
    Kosik KS; Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA. .
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    Źródło:
    Genome medicine [Genome Med] 2022 Mar 08; Vol. 14 (1), pp. 27. Date of Electronic Publication: 2022 Mar 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/genetics
    Frontotemporal Lobar Degeneration*/genetics
    Neurodegenerative Diseases*/genetics
    Colombia ; Founder Effect ; Humans ; Mutation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Quality of life in early-onset Alzheimer's disease due to a PSEN1-E280A mutation.
    Autorzy:
    Vasquez D; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia. .; Grupo de Investigación en Epidemiología y Bioestadística, Universidad CES, Medellín, Colombia. .
    Castrillón MS; Departamento de Psicología, Facultad de Ciencias Sociales y Humanas, Universidad de Antioquia, Medellín, Colombia.; Grupo Neuropsicología y Conducta, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Vega MG; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.; Grupo Neuropsicología y Conducta, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Henck CG; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Aguillon D; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.; Grupo Neuropsicología y Conducta, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Garcia-Cifuentes E; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.; Semillero de Neurociencias y Envejecimiento, Facultad de Medicina, Instituto de Envejecimiento, Pontificia Universidad Javeriana, Bogotá, Colombia.; Unidad de Neurología, Hospital Universitario San Ignacio, Bogotá, Colombia.
    Jaramillo-Jimenez A; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.; Grupo Neuropsicología y Conducta, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Stavanger, Norway.
    Velez JE; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Madrigal L; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
    Lopera F; Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
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    Źródło:
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Nov; Vol. 42 (11), pp. 4637-4645. Date of Electronic Publication: 2021 Mar 05.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Alzheimer Disease*/genetics
    Quality of Life*
    Caregivers ; Humans ; Mutation/genetics ; Presenilin-1/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Normative data stratified by age and education for a Spanish neuropsychological test battery: Results from the Colombian Alzheimer's prevention initiative registry.
    Autorzy:
    Torres VL; Department of Psychology, Florida Atlantic University, Boca Raton, Florida, USA.
    Vila-Castelar C; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
    Bocanegra Y; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Baena A; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Guzmán-Vélez E; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
    Aguirre-Acevedo DC; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Tirado V; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Munoz C; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Henao E; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Moreno S; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Giraldo M; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Acosta N; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Rios Romenets S; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Langbaum JB; Banner Alzheimer's Institute, Phoenix, Arizona, USA.
    Cho W; Genentech, South San Fransisco, California, USA.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, Arizona, USA.
    Tariot PN; Banner Alzheimer's Institute, Phoenix, Arizona, USA.
    Rosselli M; Department of Psychology, Florida Atlantic University, Boca Raton, Florida, USA.
    Quiroz YT; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
    Lopera F; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
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    Źródło:
    Applied neuropsychology. Adult [Appl Neuropsychol Adult] 2021 Mar-Apr; Vol. 28 (2), pp. 230-244. Date of Electronic Publication: 2019 Jun 23.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Alzheimer Disease*/diagnosis
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Colombia ; Female ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Reference Values ; Registries ; Retrospective Studies ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study.
    Autorzy:
    Sanchez JS; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Hanseeuw BJ; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Lopera F; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia.
    Sperling RA; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.; Brigham and Women's Hoospital, Harvard Medical School, Boston, MA, USA.
    Baena A; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia.
    Bocanegra Y; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia.
    Aguillon D; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia.
    Guzmán-Vélez E; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Pardilla-Delgado E; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Ramirez-Gomez L; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Vila-Castelar C; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Martinez JE; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Fox-Fuller JT; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.; Boston University, Boston, MA, USA.
    Ramos C; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia.
    Ochoa-Escudero M; Hospital Pablo Tobón Uribe, Medellín, Colombia.
    Alvarez S; Hospital Pablo Tobón Uribe, Medellín, Colombia.
    Jacobs HIL; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.; Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
    Schultz AP; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Gatchel JR; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Becker JA; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Katz SR; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Mayblyum DV; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Price JC; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Johnson KA; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA.; Brigham and Women's Hoospital, Harvard Medical School, Boston, MA, USA.
    Quiroz YT; Massachusetts General Hoospital, Harvard Medical School, Boston, MA, USA. .; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellin, Colombia. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2021 Jan 15; Vol. 13 (1), pp. 27. Date of Electronic Publication: 2021 Jan 15.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/diagnostic imaging
    Alzheimer Disease*/genetics
    Amyloid beta-Peptides ; Biomarkers ; Boston ; Colombia ; Cross-Sectional Studies ; Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; tau Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer's disease.
    Autorzy:
    Vila-Castelar C; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Muñoz N; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Papp KV; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Amariglio RE; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Baena A; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Guzmán-Vélez E; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Bocanegra Y; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Sanchez JS; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Johnson KA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Sperling RA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
    Lopera F; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
    Rentz DM; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
    Quiroz YT; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. .; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. .; Grupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2020 Sep 10; Vol. 12 (1), pp. 104. Date of Electronic Publication: 2020 Sep 10.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/diagnostic imaging
    Alzheimer Disease*/genetics
    Adult ; Cognition ; Humans ; Latin America ; Memory ; Positron-Emission Tomography ; Presenilin-1/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease.
    Autorzy:
    Norton DJ; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.; Gordon College, Wenham, MA, USA.
    Parra MA; School of Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.; Autonomous University of the Caribbean, Barranquilla, Colombia.
    Sperling RA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
    Baena A; Grupo de Neurociencias, Universidad de Antioquia, Medellin, Antioquia, Colombia.
    Guzman-Velez E; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Jin DS; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Andrea N; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Khang J; Gordon College, Wenham, MA, USA.
    Schultz A; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.
    Rentz DM; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Pardilla-Delgado E; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Fuller J; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.
    Johnson K; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.
    Reiman EM; Banner Alzheimer's Institute, Phoenix, AZ, USA.
    Lopera F; Grupo de Neurociencias, Universidad de Antioquia, Medellin, Antioquia, Colombia.
    Quiroz YT; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA. .; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA. .; Grupo de Neurociencias, Universidad de Antioquia, Medellin, Antioquia, Colombia. .; Departments of Psychiatry and Neurology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Rm 10.014, Boston, MA, 02129, USA. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2020 Aug 21; Vol. 12 (1), pp. 99. Date of Electronic Publication: 2020 Aug 21.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/diagnostic imaging
    Alzheimer Disease*/genetics
    Cognitive Dysfunction*/diagnostic imaging
    Cognitive Dysfunction*/genetics
    Amyloid beta-Peptides ; Cross-Sectional Studies ; Humans ; Magnetic Resonance Imaging ; Memory, Short-Term ; Positron-Emission Tomography ; Presenilin-1/genetics ; tau Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications.
    Autorzy:
    Soto-Mercado V; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), SIU Medellin, Medellin, Colombia.
    Mendivil-Perez M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), SIU Medellin, Medellin, Colombia.
    Velez-Pardo C; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), SIU Medellin, Medellin, Colombia.
    Lopera F; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), SIU Medellin, Medellin, Colombia.
    Jimenez-Del-Rio M; Neuroscience Research Group, Medical Research Institute, Faculty of Medicine, University of Antioquia (UdeA), SIU Medellin, Medellin, Colombia.
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    Źródło:
    PloS one [PLoS One] 2020 May 21; Vol. 15 (5), pp. e0221669. Date of Electronic Publication: 2020 May 21 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/metabolism
    Alzheimer Disease*/pathology
    Cholinergic Neurons*/metabolism
    Cholinergic Neurons*/pathology
    Mesenchymal Stem Cells*/metabolism
    Mesenchymal Stem Cells*/pathology
    Presenilin-1*/genetics
    Presenilin-1*/metabolism
    Umbilical Cord*/metabolism
    Umbilical Cord*/pathology
    Amyloid Precursor Protein Secretases/metabolism ; Apoptosis ; Aspartic Acid Endopeptidases/metabolism ; Calcium/metabolism ; Humans ; Mutation ; Oxidative Stress ; tau Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease.
    Autorzy:
    Hanseeuw BJ; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.; Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
    Lopera F; Universidad de Antioquia, Medellín, Colombia.
    Sperling RA; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
    Norton DJ; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Guzman-Velez E; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Baena A; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Pardilla-Delgado E; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Schultz AP; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Gatchel J; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Jin D; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.
    Chen K; Banner Alzheimer Institute, Phoenix, AZ, USA.
    Reiman EM; Banner Alzheimer Institute, Phoenix, AZ, USA.
    Johnson KA; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA.; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
    Quiroz YT; Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Suite 10.014, Charlestown, Boston, MA, 02119, USA. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2019 Feb 04; Vol. 11 (1), pp. 17. Date of Electronic Publication: 2019 Feb 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Heterozygote*
    Alzheimer Disease/*metabolism
    Amyloid/*metabolism
    Corpus Striatum/*metabolism
    Memory Disorders/*metabolism
    Tauopathies/*metabolism
    Adult ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/genetics ; Amyloid/genetics ; Corpus Striatum/diagnostic imaging ; Cross-Sectional Studies ; Female ; Humans ; Male ; Memory Disorders/diagnostic imaging ; Memory Disorders/genetics ; Middle Aged ; Positron-Emission Tomography/trends ; Tauopathies/diagnostic imaging ; Tauopathies/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Amyloid-beta immunotherapy: the hope for Alzheimer disease?
    Autorzy:
    Barrera-Ocampo A; Departamento de Ciencias Farmacéuticas , Grupo de Investigación Natura, Facultad de Ciencias Naturales , Universidad Icesi , Cali, Colombia.
    Lopera F; Grupo de Neurociencias de Antioquia , Escuela de Medicina, Universidad de Antioquia, Medellin, Colombia.
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    Źródło:
    Colombia medica (Cali, Colombia) [Colomb Med (Cali)] 2016 Dec 30; Vol. 47 (4), pp. 203-212. Date of Electronic Publication: 2016 Dec 30.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Alzheimer Disease/*therapy
    Amyloid beta-Peptides/*immunology
    Immunotherapy/*methods
    Alzheimer Disease/immunology ; Alzheimer Disease/physiopathology ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Disease Progression ; Humans ; Peptides/pharmacology ; Peptides/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease.
    Autorzy:
    Vélez JI; The Arcos-Burgos Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
    Rivera D; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
    Mastronardi CA; The Arcos-Burgos Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
    Patel HR; The Arcos-Burgos Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
    Tobón C; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
    Villegas A; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
    Cai Y; The Arcos-Burgos Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
    Easteal S; The Easteal Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
    Lopera F; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
    Arcos-Burgos M; The Arcos-Burgos Group, Department of Genome Sciences, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia; Neuroscience Research Group, University of Antioquia, Medellín, Colombia.
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    Źródło:
    Neural plasticity [Neural Plast] 2016; Vol. 2016, pp. 9760314. Date of Electronic Publication: 2016 Jan 05.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mutation, Missense*
    Alzheimer Disease/*genetics
    Carrier Proteins/*genetics
    Presenilin-1/*genetics
    Age of Onset ; Exons ; Female ; Genetic Predisposition to Disease ; Humans ; Intracellular Signaling Peptides and Proteins ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cognitive changes in the preclinical phase of familial Alzheimer's disease.
    Autorzy:
    Arango-Lasprilla JC; Neuroscience Group, University of Antioquia, Medellín, Colombia. />Cuetos F
    Valencia C
    Uribe C
    Lopera F
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    Źródło:
    Journal of clinical and experimental neuropsychology [J Clin Exp Neuropsychol] 2007 Nov; Vol. 29 (8), pp. 892-900. Date of Electronic Publication: 2007 Feb 19.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*complications
    Cognition/*physiology
    Cognition Disorders/*etiology
    Presenilin-1/*genetics
    Recognition, Psychology/*physiology
    Verbal Behavior/*physiology
    Adult ; Alzheimer Disease/genetics ; Alzheimer Disease/physiopathology ; Chromosomes, Human, Pair 14/genetics ; Cognition Disorders/genetics ; Cognition Disorders/physiopathology ; Female ; Heterozygote ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Pedigree ; Reference Values
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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