Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Lopes, JP"" wg kryterium: Autor


Tytuł:
Adenosine A 2A Receptor Up-Regulation Pre-Dates Deficits of Synaptic Plasticity and of Memory in Mice Exposed to Aβ 1-42 to Model Early Alzheimer's Disease.
Autorzy:
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Silva AC; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Agostinho P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2023 Jul 28; Vol. 13 (8). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/chemically induced
Animals ; Mice ; Up-Regulation ; Receptor, Adenosine A2A ; Neuronal Plasticity ; Adenosine ; Memory Disorders/chemically induced
Czasopismo naukowe
Tytuł:
The impact of inosine on hippocampal synaptic transmission and plasticity involves the release of adenosine through equilibrative nucleoside transporters rather than the direct activation of adenosine receptors.
Autorzy:
Valada P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal.
Hinz S; Pharmaceutical & Medicinal Chemistry, University of Bonn, 53121, Bonn, Germany.
Vielmuth C; Pharmaceutical & Medicinal Chemistry, University of Bonn, 53121, Bonn, Germany.
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal. .; Faculty of Medicine, University of Coimbra, Coimbra, Portugal. .
Müller CE; Pharmaceutical & Medicinal Chemistry, University of Bonn, 53121, Bonn, Germany.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal.
Pokaż więcej
Źródło:
Purinergic signalling [Purinergic Signal] 2023 Jun; Vol. 19 (2), pp. 451-461. Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine*/metabolism
Nucleosides*/metabolism
Rats ; Humans ; Animals ; Receptor, Adenosine A1/metabolism ; Synaptic Transmission/physiology ; Purinergic P1 Receptor Antagonists/pharmacology ; Inosine/pharmacology ; Hippocampus/metabolism
Czasopismo naukowe
Tytuł:
Adenosine A 2A Receptors Shut Down Adenosine A 1 Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation.
Autorzy:
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Olaio S; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Tomé AR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3000-534 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2023 Apr 21; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Long-Term Potentiation*
Receptor, Adenosine A2A*/metabolism
Adenosine/pharmacology ; Hippocampus/metabolism ; Synaptic Transmission ; Animals ; Mice
Czasopismo naukowe
Tytuł:
Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's Disease.
Autorzy:
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Silva JS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Santos J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Rodrigues MS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Madeira D; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Oliveira A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Moreira-de-Sá A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Lourenço VS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Rolo AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal.
Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal.
Palmeira CM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3004-531 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Agostinho P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 09; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Prefrontal Cortex*/metabolism
Sirtuin 1*/genetics
Sirtuin 1*/metabolism
Animals ; Female ; Mice ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Disease Models, Animal ; Down-Regulation ; Hippocampus/metabolism ; Long-Term Potentiation/physiology ; Maze Learning ; Mice, Transgenic
Czasopismo naukowe
Tytuł:
Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids.
Autorzy:
Alves-Lopes JP; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, Solna, 17164 Stockholm, Sweden. Electronic address: joao.pedro.lopes@ki.se.
Wong FCK; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Tang WWC; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Gruhn WH; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Ramakrishna NB; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK; Genome Institute of Singapore, A(∗)STAR, Biopolis, Singapore 138672, Singapore.
Jowett GM; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Jahnukainen K; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, Solna, 17164 Stockholm, Sweden; New Children's Hospital, Paediatric Research Centre, University of Helsinki and Helsinki University Hospital, Pl 281, 00029 Helsinki, Finland.
Surani MA; Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. Electronic address: .
Pokaż więcej
Źródło:
Cell reports [Cell Rep] 2023 Jan 31; Vol. 42 (1), pp. 111907. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Semen*
Germ Cells*
Humans ; Male ; Cell Differentiation ; Embryo, Mammalian ; Organoids
Czasopismo naukowe
Tytuł:
Epigenetic resetting in the human germ line entails histone modification remodeling.
Autorzy:
Gruhn WH; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.
Tang WWC; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.
Dietmann S; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge CB2 0AW, UK.; Institute for Informatics, Washington University School of Medicine, St. Louis, MO, USA.
Alves-Lopes JP; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Penfold CA; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
Wong FCK; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.
Ramakrishna NB; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Genome Institute of Singapore, A*STAR, Biopolis, Singapore 138672, Singapore.
Surani MA; Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Cambridge CB2 1QN, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge CB2 3EL, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge CB2 0AW, UK.
Pokaż więcej
Źródło:
Science advances [Sci Adv] 2023 Jan 18; Vol. 9 (3), pp. eade1257. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Histone Code*
DNA Methylation*
Animals ; Humans ; DNA Transposable Elements/genetics ; Epigenesis, Genetic ; Germ Cells ; Mammals/genetics
Czasopismo naukowe
Tytuł:
Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas.
Autorzy:
Lopes CR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Oliveira A; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gaspar I; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Rodrigues MS; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Santos J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Szabó E; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Silva HB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Tomé ÂR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.
Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Agostinho P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Carvalho RA; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2023 Jan 04; Vol. 13 (1). Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Caffeine*/pharmacology
Adenosine*/pharmacology
Adenosine*/metabolism
Male ; Mice ; Animals ; Prospective Studies ; Receptors, Purinergic P1/metabolism ; Hippocampus/metabolism
Czasopismo naukowe
Tytuł:
Pathogenesis and virulence of Candida albicans .
Autorzy:
Lopes JP; From the Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology (LCIM), National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD, USA.
Lionakis MS; From the Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology (LCIM), National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD, USA.
Pokaż więcej
Źródło:
Virulence [Virulence] 2022 Dec; Vol. 13 (1), pp. 89-121.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:
Candida albicans*
Candidiasis*/microbiology
Dysbiosis ; Humans ; Symbiosis ; Virulence
Czasopismo naukowe
Tytuł:
CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A 2A Receptor-Mediated Control of Fear Memory and Amygdala Plasticity.
Autorzy:
Simões AP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gonçalves FQ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Rial D; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Ferreira SG; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Canas PM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 24; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
5'-Nucleotidase*/genetics
5'-Nucleotidase*/metabolism
Receptor, Adenosine A2A*/genetics
Receptor, Adenosine A2A*/metabolism
Mice ; Animals ; Adenosine/metabolism ; Mice, Inbred C57BL ; Amygdala/metabolism ; Mice, Knockout ; Fear/physiology ; Adenosine Diphosphate ; Adenosine Triphosphate/metabolism
Czasopismo naukowe
Tytuł:
Thebromine Targets Adenosine Receptors to Control Hippocampal Neuronal Function and Damage.
Autorzy:
Valada P; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Alçada-Morais S; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Cunha RA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Lopes JP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 10; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 10.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine Deaminase*/metabolism
Caffeine*/metabolism
Caffeine*/pharmacology
Animals ; Hippocampus/metabolism ; Mice ; Neuronal Plasticity ; Receptor, Adenosine A2A/metabolism ; Synapses/metabolism ; Theobromine/pharmacology
Czasopismo naukowe
Tytuł:
Single-cell roadmap of human gonadal development.
Autorzy:
Garcia-Alonso L; Wellcome Sanger Institute, Cambridge, UK.
Lorenzi V; Wellcome Sanger Institute, Cambridge, UK.
Mazzeo CI; Wellcome Sanger Institute, Cambridge, UK.
Alves-Lopes JP; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge, UK.
Roberts K; Wellcome Sanger Institute, Cambridge, UK.
Sancho-Serra C; Wellcome Sanger Institute, Cambridge, UK.
Engelbert J; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Marečková M; Wellcome Sanger Institute, Cambridge, UK.; Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Gruhn WH; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge, UK.
Botting RA; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Li T; Wellcome Sanger Institute, Cambridge, UK.
Crespo B; Great Ormond Street Institute of Child Health, University College London, London, UK.
van Dongen S; Wellcome Sanger Institute, Cambridge, UK.
Kiselev VY; Wellcome Sanger Institute, Cambridge, UK.
Prigmore E; Wellcome Sanger Institute, Cambridge, UK.
Herbert M; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Moffett A; University of Cambridge Centre for Trophoblast Research, Department of Pathology, University of Cambridge, Cambridge, UK.
Chédotal A; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Bayraktar OA; Wellcome Sanger Institute, Cambridge, UK.
Surani A; Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Physiology, Development and Neuroscience Department, University of Cambridge, Cambridge, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge, UK.
Haniffa M; Wellcome Sanger Institute, Cambridge, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Vento-Tormo R; Wellcome Sanger Institute, Cambridge, UK. .
Pokaż więcej
Źródło:
Nature [Nature] 2022 Jul; Vol. 607 (7919), pp. 540-547. Date of Electronic Publication: 2022 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Lineage*
Germ Cells*/cytology
Germ Cells*/metabolism
Ovary*/cytology
Ovary*/embryology
Sex Differentiation*/genetics
Single-Cell Analysis*
Testis*/cytology
Testis*/embryology
Animals ; Chromatin/genetics ; Chromatin/metabolism ; Female ; Granulosa Cells/cytology ; Granulosa Cells/metabolism ; Humans ; Immunoglobulins ; Macrophages/metabolism ; Male ; Membrane Glycoproteins ; Membrane Proteins ; Mice ; Microscopy, Fluorescence ; PAX8 Transcription Factor ; Pregnancy ; Pregnancy Trimester, First ; Pregnancy Trimester, Second ; Receptors, Immunologic ; Transcriptome
Czasopismo naukowe
Tytuł:
Effects of Mechanical Deformation on the Opto-Electronic Responses, Reactivity, and Performance of Conjugated Polymers: A DFT Study.
Autorzy:
Cachaneski-Lopes JP; POSMAT, School of Sciences, São Paulo State University (UNESP), Bauru 17033-360, SP, Brazil.
Batagin-Neto A; POSMAT, School of Sciences, São Paulo State University (UNESP), Bauru 17033-360, SP, Brazil.; Institute of Science and Engineering, São Paulo State University (UNESP), Itapeva 18409-010, SP, Brazil.
Pokaż więcej
Źródło:
Polymers [Polymers (Basel)] 2022 Mar 26; Vol. 14 (7). Date of Electronic Publication: 2022 Mar 26.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid-β peptide exposure.
Autorzy:
Lopes CR; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Amaral IM; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
Pereira MF; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
Lopes JP; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
Madeira D; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Canas PM; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
Cunha RA; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Agostinho P; Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Pokaż więcej
Źródło:
Journal of neurochemistry [J Neurochem] 2022 Mar; Vol. 160 (5), pp. 556-567. Date of Electronic Publication: 2022 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/pathology
Amyloid beta-Peptides*/metabolism
Animals ; Astrocytes/metabolism ; Disease Models, Animal ; Hippocampus ; Long-Term Potentiation/physiology ; Mice ; Neuronal Plasticity/physiology ; Peptide Fragments/pharmacology
Czasopismo naukowe
Tytuł:
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.
Autorzy:
He M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Electronic address: .
Saeed MB; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Record J; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Keszei M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Gonçalves Pinho L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Vasconcelos-Fontes L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
D'Aulerio R; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Vieira R; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Oliveira MMS; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Geyer C; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Bohaumilitzky L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Thiemann M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Deordieva E; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Buedts L; Center for Human Genetics, University Hospital Leuven, Leuven, Belgium.
Matias Lopes JP; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Pershin D; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Hammarström L; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Xia Y; Department of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China.
Zhao X; Chongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Cunningham-Rundles C; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.
Thrasher AJ; UCL Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Burns SO; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom; Institute of Immunity and Transplantation, University College London, London, United Kingdom.
Cotta-de-Almeida V; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Liu C; Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China.
Shcherbina A; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Vandenberghe P; Center for Human Genetics, University Hospital Leuven, Leuven, Belgium.
Westerberg LS; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom. Electronic address: .
Pokaż więcej
Źródło:
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Mar; Vol. 149 (3), pp. 1069-1084. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes*/cytology
Neutropenia*/genetics
Wiskott-Aldrich Syndrome Protein*/metabolism
Animals ; Cell Division ; Genetic Diseases, X-Linked ; Humans ; Immunoglobulin A ; Mice ; Plasma Cells/pathology
Czasopismo naukowe
Tytuł:
Self-organising human gonads generated by a Matrigel-based gradient system.
Autorzy:
Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Alves-Lopes JP; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.; Present address: Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Road, Cambridge, CB2 1QN, UK.
Harteveld F; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Mitchell RT; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, EH16 4TJ, UK.; Royal Hospital for Children and Young People, 9 Sciennes Road, Edinburgh, EH9 1LF, Scotland, UK.
Åkesson E; Department of Neurobiology, Care Sciences & Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.; The R&D Unit, Stockholms Sjukhem, Stockholm, Sweden.
Söder O; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden. .
Pokaż więcej
Źródło:
BMC biology [BMC Biol] 2021 Sep 23; Vol. 19 (1), pp. 212. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sertoli Cells*
Testis*
Animals ; Collagen ; Drug Combinations ; Female ; Gonads ; Humans ; Laminin ; Male ; Proteoglycans ; Rats ; Suspensions
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies