- Tytuł:
- Distinct roles of RAD52 and POLQ in chromosomal break repair and replication stress response.
- Autorzy:
- Źródło:
- PLoS genetics [PLoS Genet] 2019 Aug 05; Vol. 15 (8), pp. e1008319. Date of Electronic Publication: 2019 Aug 05 (Print Publication: 2019).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Recombinational DNA Repair*
DNA-Directed DNA Polymerase/*genetics
Drug Resistance, Neoplasm/*genetics
Neoplasms/*genetics
Rad52 DNA Repair and Recombination Protein/*genetics
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Cell Line, Tumor ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; DNA Breaks, Double-Stranded/drug effects ; DNA Replication/drug effects ; DNA-Directed DNA Polymerase/metabolism ; Humans ; Mutation ; Neoplasms/drug therapy ; Rad52 DNA Repair and Recombination Protein/metabolism ; Synthetic Lethal Mutations ; DNA Polymerase theta
Czasopismo naukowe