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Tytuł :
Knockdown of circular RNA circ-FARSA restricts colorectal cancer cell growth through regulation of miR-330-5p/LASP1 axis.
Autorzy :
Lu C; Oncology Department, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan province, China.
Fu L; Oncology Department, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan province, China.
Qian X; Oncology Department, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan province, China.
Dou L; Oncology Department, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan province, China.
Cang S; Oncology Department, Henan Provincial People's Hospital, Zhengzhou, 450003, Henan province, China. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2020 Aug 15; Vol. 689, pp. 108434. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Adaptor Proteins, Signal Transducing/*genetics
Colorectal Neoplasms/*genetics
Cytoskeletal Proteins/*genetics
LIM Domain Proteins/*genetics
MicroRNAs/*genetics
RNA, Circular/*genetics
Animals ; Carcinogenesis/genetics ; Carcinogenesis/pathology ; Cell Line, Tumor ; Cell Proliferation ; Colorectal Neoplasms/pathology ; Female ; Gene Knockdown Techniques ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Up-Regulation
Czasopismo naukowe
Tytuł :
ROS-mediated miR-21-5p regulates the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4.
Autorzy :
Zhang Y; School of Medicine, Hunan Normal University, Changsha, 410081, PR China; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Xiao Y; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Ma Y; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Liang N; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Liang Y; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Lu C; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China.
Xiao F; Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410078, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Mar 15; Vol. 191, pp. 110160. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Apoptosis Regulatory Proteins/*genetics
Cell Proliferation/*drug effects
Chromium/*toxicity
Hepatocytes/*drug effects
MicroRNAs/*genetics
RNA-Binding Proteins/*genetics
Reactive Oxygen Species/*metabolism
Apoptosis/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation/drug effects ; Hepatocytes/metabolism ; Humans ; Mitochondria/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Inhibition of miR‑155‑5p attenuates the valvular damage induced by rheumatic heart disease.
Autorzy :
Chen A; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Wen J; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Lu C; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Lin B; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Xian S; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Huang F; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Wu Y; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Zeng Z; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
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Źródło :
International journal of molecular medicine [Int J Mol Med] 2020 Feb; Vol. 45 (2), pp. 429-440. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*
MicroRNAs/*genetics
Rheumatic Heart Disease/*genetics
Adenoviridae/genetics ; Animals ; Female ; Genetic Therapy ; Genetic Vectors/genetics ; Genetic Vectors/therapeutic use ; Heart Valves/metabolism ; Heart Valves/pathology ; Rats, Inbred Lew ; Rheumatic Heart Disease/pathology ; Rheumatic Heart Disease/therapy
Czasopismo naukowe
Tytuł :
MiR-199a-5p Targets ZEB1 to Inhibit the Epithelial-Mesenchymal Transition of Ovarian Ectopic Endometrial Stromal Cells Via PI3K/Akt/mTOR Signal Pathway In Vitro and In Vivo.
Autorzy :
Liu Y; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Lu C; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Fan L; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Wang J; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Li T; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Liu Z; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Sheng J; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Qian R; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Duan A; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Lu D; Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China. .
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Źródło :
Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2020 Jan; Vol. 27 (1), pp. 110-118. Date of Electronic Publication: 2020 Jan 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endometriosis/*metabolism
Epithelial-Mesenchymal Transition/*physiology
MicroRNAs/*metabolism
Signal Transduction/*physiology
Stromal Cells/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Adult ; Animals ; Cell Proliferation ; Disease Models, Animal ; Disease Progression ; Female ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; TOR Serine-Threonine Kinases/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
MiR-495 regulates macrophage M1/M2 polarization and insulin resistance in high-fat diet-fed mice via targeting FTO.
Autorzy :
Hu F; Department of Cardiology, Tianjin First Central Hospital, No. 24 Fukang Road, Tianjin, 300192, Nankai District, China.
Tong J; Department of Endocrinology, Tianjin First Central Hospital, Tianjin, 300192, Nankai District, China.
Deng B; Clinical Laboratory of Metabolic Diseases Hospital of Tianjin Medical University, Tianjin, 300070, Heping District, China.
Zheng J; Department of Cardiology, Tianjin First Central Hospital, No. 24 Fukang Road, Tianjin, 300192, Nankai District, China.
Lu C; Department of Cardiology, Tianjin First Central Hospital, No. 24 Fukang Road, Tianjin, 300192, Nankai District, China. .
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Źródło :
Pflugers Archiv : European journal of physiology [Pflugers Arch] 2019 Dec; Vol. 471 (11-12), pp. 1529-1537. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji :
Journal Article
MeSH Terms :
Alpha-Ketoglutarate-Dependent Dioxygenase FTO/*metabolism
Insulin Resistance/*physiology
Macrophages/*metabolism
MicroRNAs/*metabolism
Adipose Tissue/metabolism ; Animals ; Body Weight/physiology ; Diabetes Mellitus, Type 2/metabolism ; Diet, High-Fat ; Disease Models, Animal ; Inflammation/metabolism ; Macrophage Activation/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/metabolism
Czasopismo naukowe
Tytuł :
LncRNA PART-1 targets TGFBR2/Smad3 to regulate cell viability and apoptosis of chondrocytes via acting as miR-590-3p sponge in osteoarthritis.
Autorzy :
Lu C; Department of Joint Surgery, Xi'an Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Li Z; Department of Emergency, the First Affiliated Hospital of Xi'an Medical University, Xi'an, China.
Hu S; Department of Joint Surgery, Xi'an Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Cai Y; Department of Joint Surgery, Xi'an Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Peng K; Department of Joint Surgery, Xi'an Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Dec; Vol. 23 (12), pp. 8196-8205. Date of Electronic Publication: 2019 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*genetics
Chondrocytes/*metabolism
MicroRNAs/*genetics
Osteoarthritis/*genetics
RNA, Long Noncoding/*genetics
Receptor, Transforming Growth Factor-beta Type II/*genetics
Smad3 Protein/*genetics
Cell Line ; Cell Survival/genetics ; Chondrocytes/cytology ; Gene Expression Regulation ; Humans ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; RNA Interference ; RNA, Untranslated/genetics ; Receptor, Transforming Growth Factor-beta Type II/metabolism ; Signal Transduction/genetics ; Smad3 Protein/metabolism
Czasopismo naukowe
Tytuł :
MicroRNA-495 serves as a diagnostic biomarker in patients with sepsis and regulates sepsis-induced inflammation and cardiac dysfunction.
Autorzy :
Guo H; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China.; Department of Burns Surgery, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, People's Republic of China.
Tang L; Department of Rehabilitation, Wenzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang, Chinese Medical University, Wenzhou, 32500, People's Republic of China.
Xu J; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China.
Lin C; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China.
Ling X; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China.
Lu C; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China. .
Liu Z; Department of Burns Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang Street, Wenzhou, 325000, Zhejiang, People's Republic of China. .
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Źródło :
European journal of medical research [Eur J Med Res] 2019 Nov 26; Vol. 24 (1), pp. 37. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Gene Expression Regulation*
Biomarkers/*blood
Heart Diseases/*diagnosis
Inflammation/*diagnosis
MicroRNAs/*genetics
Sepsis/*diagnosis
Animals ; Case-Control Studies ; Cytokines/metabolism ; Female ; Follow-Up Studies ; Heart Diseases/blood ; Heart Diseases/etiology ; Humans ; Inflammation/blood ; Inflammation/etiology ; Male ; MicroRNAs/blood ; Middle Aged ; Prognosis ; ROC Curve ; Rats ; Rats, Sprague-Dawley ; Sepsis/complications ; Sepsis/genetics
Czasopismo naukowe
Tytuł :
LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis.
Autorzy :
Fu D; Children's Hospital of Shanghai, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Lu C; Department of Spinal Surgery, Changhai Hospital, Affiliated to Naval Military Medical University, Shanghai, China.
Qu X; The Department of Oral Maxillofacial and Head Neck Oncology in the Ninth Hospital Affiliated Shanghai Jiaotong University, Shanghai, China.
Li P; Children's Hospital of Shanghai, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen K; Hai'an People's Hospital, Hai'an, Nantong, Jiangsu, China.
Shan L; Department of Orthopedics, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhu X; Department of Orthopedics, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło :
Aging [Aging (Albany NY)] 2019 Oct 10; Vol. 11 (19), pp. 8374-8385. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Apoptosis*/genetics
Osteosarcoma*/genetics
Osteosarcoma*/metabolism
Aging/*physiology
Chromosomal Proteins, Non-Histone/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Computational Biology ; Drug Resistance/genetics ; Gene Expression Regulation, Neoplastic ; Humans
Czasopismo naukowe
Tytuł :
Knockdown of differentiation antagonizing non-protein coding RNA exerts anti-tumor effect by up-regulating miR-214 in endometrial carcinoma.
Autorzy :
Sun J; Department of Obstetrics and Gynecology, Shanxian Central Hospital, No. 1 Wenhua Road, Heze, 274300, Shandong, China.
Gao S; Department of Obstetrics and Gynecology, Shanxian Central Hospital, No. 1 Wenhua Road, Heze, 274300, Shandong, China.
Lu C; Department of Obstetrics and Gynecology, Shanxian Central Hospital, No. 1 Wenhua Road, Heze, 274300, Shandong, China. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2019 Oct; Vol. 460 (1-2), pp. 9-15. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Endometrial Neoplasms/*genetics
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Up-Regulation/*genetics
Apoptosis/genetics ; Base Sequence ; Cell Line, Tumor ; Cell Proliferation/genetics ; Endometrial Neoplasms/pathology ; Female ; Gene Knockdown Techniques ; Humans ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics
Czasopismo naukowe
Tytuł :
Circ-EIF4G3 promotes the development of gastric cancer by sponging miR-335.
Autorzy :
Wang Q; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Wang T; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of General Surgery, Nanjing Red Cross Hospital, Nanjing, China.
Hu Y; Department of General Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jiang W; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Lu C; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Zheng W; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Zhang W; Department of Gastroenterology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: .
Chen Z; Department of General Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu, China. Electronic address: .
Cao H; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: .
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Źródło :
Pathology, research and practice [Pathol Res Pract] 2019 Sep; Vol. 215 (9), pp. 152507. Date of Electronic Publication: 2019 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Eukaryotic Initiation Factor-4G/*genetics
Gene Expression Regulation, Neoplastic/*genetics
MicroRNAs/*genetics
RNA, Circular/*genetics
Stomach Neoplasms/*pathology
Adult ; Aged ; Cell Movement/genetics ; Cell Proliferation/genetics ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness/genetics ; Stomach Neoplasms/genetics
Czasopismo naukowe
Tytuł :
MicroRNA-449b-5p Suppresses Proliferation, Migration, and Invasion of Osteosarcoma by Targeting c-Met.
Autorzy :
Li Q; Department of Laboratory Medicine, Weifang Medical University, Weifang, Shandong, China (mainland).
Lu C; School of Clinical Medicine, Weifang Medical University, Weifang, Shandong, China (mainland).
Wang J; Department of Pathology, Weifang Maternal and Child Health Care Hospital, Weifang, Shandong, China (mainland).
Gao M; Department of Otolaryngology, Weifang People's Hospital, Weifang, Shandong, China (mainland).
Gao W; School of Clinical Medicine, Weifang Medical University, Weifang, Shandong, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2019 Aug 19; Vol. 25, pp. 6236-6243. Date of Electronic Publication: 2019 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*metabolism
Bone Neoplasms/*pathology
MicroRNAs/*metabolism
Osteosarcoma/*metabolism
Osteosarcoma/*pathology
Proto-Oncogene Proteins c-met/*metabolism
Adult ; Bone Neoplasms/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Disease Progression ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; MicroRNAs/genetics ; Neoplasm Invasiveness ; Osteosarcoma/genetics ; Proto-Oncogene Proteins c-met/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
LINC00909 promotes tumor progression in human glioma through regulation of miR-194/MUC1-C axis.
Autorzy :
Liu Z; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China; Department of Neurosurgery, 91 Central Hospital of People's Liberation Army, Jiaozuo Henan Province, 454150, China.
Lu C; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Hu H; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Cai Z; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China; Department of Pharmaceutics, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.
Liang Q; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Sun W; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Jiang L; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China. Electronic address: .
Hu G; Department of Neurosurgery, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2019 Aug; Vol. 116, pp. 108965. Date of Electronic Publication: 2019 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Progression*
Brain Neoplasms/*genetics
Brain Neoplasms/*pathology
Glioma/*genetics
Glioma/*pathology
MicroRNAs/*metabolism
Mucin-1/*metabolism
RNA, Long Noncoding/*metabolism
Animals ; Base Sequence ; Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics ; Up-Regulation/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Identification and functional characterization of microRNAs in rat Leydig cells during development from the progenitor to the adult stage.
Autorzy :
Chen H; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Department of Cell Biology, Jinan University, Guangzhou, China.
Guo X; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Department of Cell Biology, Jinan University, Guangzhou, China.
Xiao X; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Department of Cell Biology, Jinan University, Guangzhou, China.
Ye L; Department of Pediatrics, Peking University First Hospital, Beijing, China.
Huang Y; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Department of Cell Biology, Jinan University, Guangzhou, China; Biopharmaceutical Research and Development Center, Jinan University, Guangzhou, China.
Lu C; Department of Developmental Biology and Regenerative Medicine, Jinan University, Guangzhou, China. Electronic address: .
Su Z; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Department of Cell Biology, Jinan University, Guangzhou, China; Biopharmaceutical Research and Development Center, Jinan University, Guangzhou, China. Electronic address: .
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Źródło :
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2019 Aug 01; Vol. 493, pp. 110453. Date of Electronic Publication: 2019 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling/*methods
Leydig Cells/*cytology
MicroRNAs/*genetics
Androstane-3,17-diol/metabolism ; Androsterone/metabolism ; Animals ; Cell Differentiation ; Cell Proliferation ; Gene Expression Regulation, Developmental ; Leydig Cells/metabolism ; Male ; Rats ; Testosterone/metabolism
Czasopismo naukowe
Tytuł :
Overexpression of microRNA‑21 inhibits the growth and metastasis of melanoma cells by targeting MKK3.
Autorzy :
Zhou M; Department of Dermatology, Qilu Hospital of Shandong University, Qingdao, Shandong 266000, P.R. China.
Yu X; Department of Dermatology, Qingdao Hiser Medical Group, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong 266032, P.R. China.
Jing Z; Department of Oncology, Qingdao Hiser Medical Group, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong 266032, P.R. China.
Wu W; College of Food Science and Technology, Qingdao Agricultural University, Qingdao, Shandong 266179, P.R. China.
Lu C; Department of Emergency, Qilu Hospital of Shandong University, Qingdao, Shandong 266000, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2019 Aug; Vol. 20 (2), pp. 1797-1807. Date of Electronic Publication: 2019 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenesis/*genetics
MAP Kinase Kinase 3/*genetics
Melanoma/*genetics
MicroRNAs/*genetics
Adult ; Aged ; Apoptosis/genetics ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cell Survival/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Male ; Melanoma/pathology ; Middle Aged ; Neoplasm Metastasis ; PTEN Phosphohydrolase/genetics
Czasopismo naukowe
Tytuł :
Identifying microRNAs and Their Editing Sites in Macaca mulatta .
Autorzy :
Wang Q; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Zhao Z; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Zhang X; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.
Lu C; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Ren S; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Li S; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Guo J; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Liao P; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Jiang B; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Zheng Y; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, Yunnan, China. .; Yunnan Key Lab of Primate Biomedicine Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, Yunnan, China. .
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Źródło :
Cells [Cells] 2019 Jul 05; Vol. 8 (7). Date of Electronic Publication: 2019 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Editing*
Macaca mulatta/*genetics
MicroRNAs/*genetics
Animals ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Humans ; Molecular Sequence Annotation ; Mutation ; Polymorphism, Single Nucleotide ; RNA-Seq ; Species Specificity
Czasopismo naukowe
Tytuł :
Satb2 expression in Foxc1-promoted osteogenic differentiation of MC3T3-E1 cells is negatively regulated by microRNA-103-3p.
Autorzy :
Shen H; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Lu C; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Shi J; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Li H; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Si J; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
Shen G; Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2019 Jun 20; Vol. 51 (6), pp. 588-597.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Cell Differentiation/*genetics
Forkhead Transcription Factors/*genetics
Matrix Attachment Region Binding Proteins/*genetics
MicroRNAs/*genetics
Osteogenesis/*genetics
Transcription Factors/*genetics
Animals ; Cell Line ; Forkhead Transcription Factors/metabolism ; Gene Expression Profiling/methods ; Matrix Attachment Region Binding Proteins/metabolism ; Mice ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
Autorzy :
Wu Y; Laboratory of Medical Science, School of Medicine, Nantong University, Jiangsu 226001, China.
Chen H; Department of Gastroenterology, Affiliated Hospital of Nantong University, Jiangsu 226001, China.
Chen Y; Department of Surgery, Affiliated Hospital of Nantong University, Jiangsu 226001, China.
Qu L; Department of Gastroenterology, Affiliated Hospital of Nantong University, Jiangsu 226001, China.
Zhang E; Laboratory of Medical Science, School of Medicine, Nantong University, Jiangsu 226001, China.
Wang Z; School of Life Sciences, Nantong University, Jiangsu 226001, China.
Wu Y; Laboratory of Medical Science, School of Medicine, Nantong University, Jiangsu 226001, China.
Yang R; Laboratory of Medical Science, School of Medicine, Nantong University, Jiangsu 226001, China.
Mao R; Department of Pathophysiology, School of Medicine, Nantong University, Jiangsu 226001, China.
Lu C; Department of Gastroenterology, Affiliated Hospital of Nantong University, Jiangsu 226001, China.
Fan Y; Laboratory of Medical Science, School of Medicine, Nantong University, Jiangsu 226001, China.; Department of Immunology, School of Medicine, Nantong University, Jiangsu 226001, China.
Pokaż więcej
Źródło :
Aging [Aging (Albany NY)] 2019 Apr 29; Vol. 11 (8), pp. 2430-2446.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
3' Untranslated Regions*
MicroRNAs*
Transcriptome*
Head and Neck Neoplasms/*virology
Papillomavirus Infections/*virology
Squamous Cell Carcinoma of Head and Neck/*virology
Databases, Genetic ; Head and Neck Neoplasms/pathology ; Humans ; Papillomaviridae ; Squamous Cell Carcinoma of Head and Neck/pathology ; Up-Regulation
Czasopismo naukowe
Tytuł :
Analysis of microRNAs, phased small interfering RNAs and their potential targets in Rosarugosa Thunb.
Autorzy :
Guo J; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650500, China.
Wang Q; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650500, China.
Liu L; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China.
Ren S; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China.
Li S; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China.
Liao P; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China.
Zhao Z; Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650500, China.
Lu C; Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650500, China.
Jiang B; Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650500, China.
Sunkar R; Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, 74078, Oklahoma, USA.
Zheng Y; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650500, China. .; Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650500, China. .
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Źródło :
BMC genomics [BMC Genomics] 2019 Apr 18; Vol. 19 (Suppl 9), pp. 983. Date of Electronic Publication: 2019 Apr 18.
Typ publikacji :
Journal Article
MeSH Terms :
High-Throughput Nucleotide Sequencing/*methods
MicroRNAs/*genetics
Plant Proteins/*genetics
RNA, Plant/*genetics
RNA, Small Interfering/*genetics
Rosa/*genetics
Computational Biology ; Gene Expression Regulation, Plant ; Plant Leaves/genetics
Czasopismo naukowe
Tytuł :
Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma.
Autorzy :
Zhang Z; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yin J; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Lu C; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Wei Y; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Zeng A; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
You Y; Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. .; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 211166, China. .
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Źródło :
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Apr 16; Vol. 38 (1), pp. 166. Date of Electronic Publication: 2019 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
DNA-Binding Proteins/*genetics
Glioblastoma/*drug therapy
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Animals ; Biomarkers, Tumor/blood ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Breaks, Double-Stranded/drug effects ; Drug Resistance, Neoplasm/genetics ; Exosomes/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Glioblastoma/blood ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Mice ; Temozolomide/administration & dosage ; Temozolomide/adverse effects ; Xenograft Model Antitumor Assays ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe

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