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Tytuł:
Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia.
Autorzy:
Yu CH; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Chang YH; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Wang DS; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin CY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wu KH; Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Cheng CN; Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Pediatrics, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chou SW; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.
Su MY; Department of Pediatrics, China Medical University Children's Hospital, Taichung, Taiwan.
Ni YL; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Xu PY; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Lin DT; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Lin SW; Departments of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, Taipei, Taiwan.
Chen HY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Yang YL; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 10; Vol. 13 (1), pp. 490. Date of Electronic Publication: 2023 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mercaptopurine*/adverse effects
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Child ; Humans ; Alleles ; Antimetabolites, Antineoplastic/therapeutic use ; Polymerase Chain Reaction ; Pyrophosphatases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Suppressed renoprotective purines in COVID-19 patients with acute kidney injury.
Autorzy:
Jackson EK; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, 100 Technology Drive, Room 514, Pittsburgh, PA, 15219, USA. .
Kitsios GD; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Lu MY; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Schaefer CM; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kessinger CJ; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
McVerry BJ; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Morris A; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Macatangay BJC; Department of Medicine, Division of Infectious Disease, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 17; Vol. 12 (1), pp. 17353. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Acute Kidney Injury*
COVID-19*
Adenosine ; Adenosine Monophosphate ; Animals ; Guanosine/metabolism ; Guanosine Monophosphate ; Inosine/metabolism ; Purines/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Changing epidemiology and viral interplay of hepatitis B, C and D among injecting drug user-dominant prisoners in Taiwan.
Autorzy:
Lu MY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Chen CT; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Shih YL; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Tsai PC; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Hsieh MH; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Health Management Center and Department of Community Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC.
Huang CF; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Yeh ML; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Huang CI; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Wang SC; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Tsai YS; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Ko YM; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Lin CC; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Chen KY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Wei YJ; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Hsu PY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Hsu CT; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Jang TY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Liu TW; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Liang PC; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Hsieh MY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Lin ZY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Chen SC; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Huang JF; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Dai CY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Health Management Center and Department of Community Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC.
Chuang WL; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Yu ML; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC. .; Faculty of Internal Medicine and Hepatitis Research Center, College of Medicine and Center for Cohort Study and Liquid Biopsy, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC. .
Chang WY; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.; Taiwan Liver Research Foundation, Kaohsiung, Taiwan, ROC.
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 20; Vol. 11 (1), pp. 8554. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepacivirus/*isolation & purification
Hepatitis B/*epidemiology
Hepatitis B virus/*isolation & purification
Hepatitis C/*epidemiology
Hepatitis D/*epidemiology
Hepatitis Delta Virus/*isolation & purification
Substance Abuse, Intravenous/*complications
Coinfection/blood ; Coinfection/diagnosis ; Coinfection/epidemiology ; Female ; Genotype ; Hepacivirus/genetics ; Hepacivirus/immunology ; Hepatitis B/blood ; Hepatitis B/diagnosis ; Hepatitis B virus/genetics ; Hepatitis B virus/immunology ; Hepatitis C/blood ; Hepatitis C/diagnosis ; Hepatitis D/blood ; Hepatitis D/diagnosis ; Hepatitis Delta Virus/genetics ; Hepatitis Delta Virus/immunology ; Humans ; Male ; Middle Aged ; Prisoners/statistics & numerical data ; Seroepidemiologic Studies ; Taiwan/epidemiology ; Viral Load/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Treatment outcomes of pediatric acute myeloid leukemia: a retrospective analysis from 1996 to 2019 in Taiwan.
Autorzy:
Yang YL; Department of Laboratory Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Jaing TH; Department of Hematology-Oncology, Chang Gung Children's Hospital-Linkou and Chang Gung University, Taoyüan, Taiwan.
Chen SH; Department of Hematology-Oncology, Chang Gung Children's Hospital-Linkou and Chang Gung University, Taoyüan, Taiwan.
Liu HC; Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan.
Hung IJ; Department of Hematology-Oncology, Chang Gung Children's Hospital-Linkou and Chang Gung University, Taoyüan, Taiwan.
Lin DT; Department of Laboratory Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Yang CP; Department of Hematology-Oncology, Chang Gung Children's Hospital-Linkou and Chang Gung University, Taoyüan, Taiwan.
Peng CT; Division of Pediatric Hematology and Oncology, China Medical University Children's Hospital, Taichung, Taiwan.; Department of Biotechnology, Asia University, Taichung, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsiao CC; Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen JS; Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan.
Lin MT; Department of Pediatric Hematology & Oncology, Changhua Christian Children's Hospital, Changhua, Taiwan.
Wang SC; Department of Pediatric Hematology & Oncology, Changhua Christian Children's Hospital, Changhua, Taiwan.
Chang TK; Division of Pediatric Hematology and Oncology, China Medical University Children's Hospital, Taichung, Taiwan.
Huang FL; Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan.
Cheng CN; Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan.
Wu KH; Department of Pediatrics, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Sheen JM; Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Department of Pediatrics, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Chen SH; Department of Pediatrics, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Hung GY; Department of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
Yen HJ; Department of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
Hsieh YL; Department of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
Wang JL; Taipei Municipal Wan Fang Hospital, Taipei, Taiwan.
Chang YH; Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Yeh TC; Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan.
Weng TF; Department of Pediatrics, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Hou JY; Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan.
Chen BW; Division of Pediatric Hematology and Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Chen RL; Division of Pediatric Hematology and Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Wang LY; Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan.
Ho WL; School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.; Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.; Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.; Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan.
Chen YC; Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Cheng SN; Department of Pediatrics, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.
Chao YH; Department of Pediatrics, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Yang SH; Department of Pediatrics, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Huang TH; Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan.
Chou SW; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin CY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Chen HY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Chao YY; Childhood Cancer Foundation, Taipei, Taiwan.
Liang DC; Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan. .
Chang TT; Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Department of Pediatrics, Chia-Yi Christian Hospital, No 539, Rhongxiao Road, East Dist., Chia-Yi, 60002, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 15; Vol. 11 (1), pp. 5893. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukemia, Myeloid, Acute/*drug therapy
Adolescent ; Antineoplastic Agents/therapeutic use ; Child ; Child, Preschool ; Cytogenetic Analysis ; Female ; Hematopoietic Stem Cell Transplantation ; Humans ; Incidence ; Infant ; Infant, Newborn ; Leukemia, Myeloid, Acute/genetics ; Male ; Neoplasm Proteins/metabolism ; Neoplasm Recurrence, Local/pathology ; Progression-Free Survival ; Retrospective Studies ; Taiwan ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan.
Autorzy:
Hsu YC; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Yu CH; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Chen YM; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Roberts KG; Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA.
Ni YL; Department of Laboratory Medicine, National Taiwan University Hospital, 100, No 7, Chung Shan South Road, Taipei, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen SH; Department of Pediatrics, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.
Wu KH; Department of Pediatrics, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin DT; Department of Laboratory Medicine, National Taiwan University Hospital, 100, No 7, Chung Shan South Road, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Lin SW; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, 100, No 7, Chung Shan South Road, Taipei, Taiwan.
Lin ZS; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Chiu WT; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Chang CC; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan.
Ho BC; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.
Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA. .
Yu SL; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, No. 1, Changde Street, Zhongzheng District 10048, Taipei, Taiwan. .; Department of Laboratory Medicine, National Taiwan University Hospital, 100, No 7, Chung Shan South Road, Taipei, Taiwan. .; Institute of Medical Device and Imaging, College of Medicine, National Taiwan University, Taipei, Taiwan. .; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan. .; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan. .
Yang YL; Department of Laboratory Medicine, National Taiwan University Hospital, 100, No 7, Chung Shan South Road, Taipei, Taiwan. .; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 11; Vol. 11 (1), pp. 5802. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Philadelphia Chromosome*
Oncogene Proteins, Fusion/*metabolism
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*metabolism
Protein Kinases/*metabolism
Base Sequence ; Child ; Child, Preschool ; Cohort Studies ; Female ; Gene Deletion ; Gene Rearrangement/genetics ; Humans ; Immunoglobulin Heavy Chains/genetics ; Infant ; Male ; Neoplasm Proteins/metabolism ; Progression-Free Survival ; Taiwan
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia.
Autorzy:
Chang YH; Institute of Statistical Science Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan.
Yu CH; Departments of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin CY; Institute of Statistical Science Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wu KH; Department of Pediatrics, Chung Shan Medical University Hospital and School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin DT; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.; Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Laboratory Medicine, College of Medicine, National Taiwan University, 100, No 7. Chung-Shan South Road, Taipei, Taiwan.
Lin SW; Departments of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chen HY; Institute of Statistical Science Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan. .
Yang YL; Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, College of Medicine, National Taiwan University, 100, No 7. Chung-Shan South Road, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 769. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Biomarkers, Tumor/*genetics
F-Box-WD Repeat-Containing Protein 7/*genetics
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Cadherins/genetics ; Child ; Child, Preschool ; Cohort Studies ; Epidermal Growth Factor/genetics ; Epigenesis, Genetic ; Female ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Infant ; Male ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Prognosis ; Receptor, Notch1/genetics ; Survival Rate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circulating CD56+ NKG2D+ NK cells and postoperative fertility in ovarian endometrioma.
Autorzy:
Liu ZQ; Department of Obstetrics and Gynecology, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen, 518102, Guangdong, China.
Lu MY; Department of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen, 518102, Guangdong, China.
Liu B; Department of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen, 518102, Guangdong, China. .
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 29; Vol. 10 (1), pp. 18598. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
CD56 Antigen/*immunology
Endometriosis/*blood
Endometriosis/*immunology
Killer Cells, Natural/*immunology
NK Cell Lectin-Like Receptor Subfamily K/*immunology
Ovary/*immunology
Adult ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; Fertility/immunology ; Humans ; Intraepithelial Lymphocytes/immunology ; Lymphocyte Subsets/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Determination of NUDT15 variants by targeted sequencing can identify compound heterozygosity in pediatric acute lymphoblastic leukemia patients.
Autorzy:
Yu CH; Departments of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, Taipei, Taiwan.
Chang YH; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Wang DS; Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lin CY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Raghav L; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Wu KH; Division of Pediatric Hematology and Oncology, China Medical University Children's Hospital, Taichung, Taiwan.
Chou SW; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Ni YL; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongzheng Dist, Taipei City, 10041, Taiwan.
Lin DT; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongzheng Dist, Taipei City, 10041, Taiwan.
Lin SW; Departments of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, Taipei, Taiwan.
Chen HY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Yang YL; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. .; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongzheng Dist, Taipei City, 10041, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2020 Sep 01; Vol. 10 (1), pp. 14400. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heterozygote*
Polymorphism, Genetic*
High-Throughput Nucleotide Sequencing/*methods
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Pyrophosphatases/*genetics
Sequence Analysis, DNA/*methods
Adolescent ; Alleles ; Antimetabolites, Antineoplastic/adverse effects ; Child ; Child, Preschool ; Cohort Studies ; Drug Resistance, Neoplasm/genetics ; Exons ; Female ; Haplotypes ; Humans ; Infant ; Infant, Newborn ; Male ; Mercaptopurine/adverse effects ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/epidemiology ; Taiwan/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia.
Autorzy:
Yu SL; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongshan S. Rd, Zhongzheng Dist, Taipei, 100, Taiwan, ROC.; Institute of Medical Device and Imaging, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Zhang H; Department of Hematology & Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China.
Ho BC; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.
Yu CH; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chang CC; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsu YC; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ni YL; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongshan S. Rd, Zhongzheng Dist, Taipei, 100, Taiwan, ROC.
Lin KH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Chen SH; Department of Pediatrics, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.
Wu KH; Division of Pediatric Hematology &Oncology, China Medical University Children's Hospital, Taichung, Taiwan.
Wang SC; Department of Pediatrics, Changhua Christian Hospital, Changhua, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yang JJ; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Lin DT; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongshan S. Rd, Zhongzheng Dist, Taipei, 100, Taiwan, ROC.; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lin SW; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ma X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yang YL; Department of Laboratory Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung Shan S. Rd, Zhongshan S. Rd, Zhongzheng Dist, Taipei, 100, Taiwan, ROC. .; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 21; Vol. 10 (1), pp. 12074. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
Mutation*
Peptide Synthases/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Adolescent ; Alleles ; Child ; Child, Preschool ; Drug Resistance, Neoplasm/genetics ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Infant ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia.
Autorzy:
Yu CH; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin TK; Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan.; Sofiva Genomics Co., Ltd, Taipei, Taiwan.
Jou ST; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lin CY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Lin KH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Lu MY; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Chen SH; Department of Pediatrics, Taipei Medical University-Shuang Ho Hospital, Taipei, Taiwan.
Cheng CN; Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan.
Wu KH; Division of Pediatric Hematology and Oncology, China Medical University Children's Hospital, Taichung, Taiwan.
Wang SC; Department of Pediatrics, Changhua Christian Hospital, Changhua, Taiwan.
Chang HH; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Li MJ; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Pediatrics, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Ni YL; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Su YN; Sofiva Genomics Co., Ltd, Taipei, Taiwan.
Lin DT; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chen HY; Institute of Statistical Science Academia Sinica, Taipei, Taiwan.
Harrison CJ; Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.
Hung CC; Sofiva Genomics Co., Ltd, Taipei, Taiwan. .
Lin SW; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan. .
Yang YL; Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. .; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan. .; Department of Laboratory Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 13; Vol. 10 (1), pp. 11501. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pathology, Molecular*
Prognosis*
DNA Copy Number Variations/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*blood
Adolescent ; Aneuploidy ; B-Lymphocytes/pathology ; Child ; Child, Preschool ; Chromosome Aberrations ; DNA, Neoplasm/blood ; Female ; Humans ; Infant ; Male ; Multiplex Polymerase Chain Reaction/methods ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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