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    Wyświetlanie 1-17 z 17
    Tytuł:
    Closed-Loop Acoustic Stimulation During Sedation with Dexmedetomidine (CLASS-D): Protocol for a Within-Subject, Crossover, Controlled, Interventional Trial with Healthy Volunteers
    Autorzy:
    Guay CS
    Labonte AK
    Montana MC
    Landsness EC
    Lucey BP
    Kafashan M
    Haroutounian S
    Avidan MS
    Brown EN
    Palanca BJA
    Pokaż więcej
    Temat:
    sleep
    anesthesia
    consciousness
    dexmedetomidine
    electroencephalography
    acoustic stimulation
    Psychiatry
    RC435-571
    Neurophysiology and neuropsychology
    QP351-495
    Źródło:
    Nature and Science of Sleep, Vol Volume 13, Pp 303-313 (2021)
    Opis pliku:
    electronic resource
    Relacje:
    https://www.dovepress.com/closed-loop-acoustic-stimulation-during-sedation-with-dexmedetomidine--peer-reviewed-article-NSS; https://doaj.org/toc/1179-1608
    Dostęp URL:
    https://doaj.org/article/8a04c8b4d71b4c83b32710ca20b47b0a  Link otwiera się w nowym oknie
    Czasopismo naukowe
    Szczegóły
    Tytuł:
    Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways.
    Autorzy:
    Elbert DL; Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA. .
    Patterson BW; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
    Lucey BP; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St Louis, MO, USA.
    Benzinger TLS; Hope Center for Neurological Disorders, Washington University School of Medicine, St Louis, MO, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
    Bateman RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St Louis, MO, USA.
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    Źródło:
    Communications biology [Commun Biol] 2022 Jan 27; Vol. 5 (1), pp. 98. Date of Electronic Publication: 2022 Jan 27.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Proteolysis*
    Aging/*cerebrospinal fluid
    Amyloid beta-Peptides/*cerebrospinal fluid
    Blood-Brain Barrier/*physiology
    Amyloid beta-Peptides/genetics ; Humans ; Kinetics ; Models, Biological ; Mutation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans.
    Autorzy:
    Holth JK; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Fritschi SK; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Wang C; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Pedersen NP; Department of Neurology, Emory Epilepsy Center, Emory University, Atlanta, GA 30322, USA.; Program in Neuroscience, Emory University, Atlanta, GA 30322, USA.
    Cirrito JR; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Mahan TE; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Finn MB; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Manis M; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Geerling JC; Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.
    Fuller PM; Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215, USA.
    Lucey BP; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA. .; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2019 Feb 22; Vol. 363 (6429), pp. 880-884. Date of Electronic Publication: 2019 Jan 24.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Circadian Rhythm*
    Brain/*metabolism
    Extracellular Fluid/*chemistry
    Sleep/*physiology
    Sleep Deprivation/*metabolism
    Wakefulness/*physiology
    tau Proteins/*analysis
    tau Proteins/*cerebrospinal fluid
    Amyloid beta-Peptides/analysis ; Amyloid beta-Peptides/cerebrospinal fluid ; Amyloid beta-Peptides/metabolism ; Animals ; Extracellular Fluid/metabolism ; Female ; Male ; Mice ; Mice, Transgenic ; Sleep Deprivation/cerebrospinal fluid ; Wakefulness/genetics ; tau Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Diurnal oscillation of CSF Aβ and other AD biomarkers.
    Autorzy:
    Lucey BP; Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO, 63110, USA. .
    Fagan AM; Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO, 63110, USA.
    Holtzman DM; Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO, 63110, USA.
    Morris JC; Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO, 63110, USA.
    Bateman RJ; Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO, 63110, USA.
    Pokaż więcej
    Źródło:
    Molecular neurodegeneration [Mol Neurodegener] 2017 May 08; Vol. 12 (1), pp. 36. Date of Electronic Publication: 2017 May 08.
    Typ publikacji:
    Journal Article; Comment
    MeSH Terms:
    Amyloid beta-Peptides/*cerebrospinal fluid
    tau Proteins/*cerebrospinal fluid
    Alzheimer Disease/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Circadian Rhythm ; Humans ; Peptide Fragments/cerebrospinal fluid
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter.
    Autorzy:
    Lucey BP; Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 South Euclid Avenue, St Louis, MO 63110 USA ; Hope Center for Neurological Disorders, Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 South Euclid Avenue, St Louis, MO 63110 USA.
    Gonzales C; Eli Lilly and Company, Lilly Corporate Center, 893 South Delaware Avenue, Indianapolis, IN 46285 USA.
    Das U; AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 6004 USA.
    Li J; AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 6004 USA.
    Siemers ER; Eli Lilly and Company, Lilly Corporate Center, 893 South Delaware Avenue, Indianapolis, IN 46285 USA.
    Slemmon JR; Johnson and Johnson, One Johnson & Johnson Plaza, New Brunswick, NJ 08933 USA.
    Bateman RJ; Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 South Euclid Avenue, St Louis, MO 63110 USA ; Hope Center for Neurological Disorders, Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 South Euclid Avenue, St Louis, MO 63110 USA.
    Huang Y; Department of Medicine, St. Luke's Hospital, 232 South Woodsmill Road, Chesterfield, MO 63017 USA.
    Fox GB; AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 6004 USA.
    Claassen JA; Department of Geriatric Medicine, Donders Institute for Brain, Cognition, and Behaviour, Radboud Alzheimer Center, Radboud University Medical Center, Route 925, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
    Slats D; Department of Geriatric Medicine, Donders Institute for Brain, Cognition, and Behaviour, Radboud Alzheimer Center, Radboud University Medical Center, Route 925, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
    Verbeek MM; Department of Neurology, 830 TML, Neurochemistry Lab, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
    Tong G; Lundbeck LLC, Four Parkway North, Deerfield, IL 60015 USA.
    Soares H; Bristol-Myers Squibb, 311 Pennington-Rocky Hill Road, Pennington, NJ 08534 USA.
    Savage MJ; Merck and Company, RY50-1D-131, 126 East Lincoln Avenue, PO Box 2000, Rahway, NJ 07065 USA.
    Kennedy M; Merck and Company, 33 Avenue Louis Pasteur, Boston, MA 02115 USA.
    Forman M; Merck and Company, 2000 Galloping Hill Road, Kenilworth, NJ 07033 USA.
    Sjögren M; Mental Health Centre Ballerup, Capital Region of Denmark, Maglevanget 2, 2750, Ballerup, Denmark.
    Margolin R; CereSpir, Inc., 41 Madison Avenue, 31st Floor, New York, NY 10010 USA.
    Chen X; Boeringher Ingelheim, 900 Ridgebury Road, Ridgefield, CT 06877 USA.
    Farlow MR; Department of Neurology, Indiana University School of Medicine, Goodman Hall, Suite 4700, 355 West 16th Street, Indianapolis, IN 46202 USA.
    Dean RA; Eli Lilly and Company, Lilly Corporate Center, 893 South Delaware Avenue, Indianapolis, IN 46285 USA.
    Waring JF; AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 6004 USA.
    Pokaż więcej
    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2015 Jul 29; Vol. 7 (1), pp. 53. Date of Electronic Publication: 2015 Jul 29 (Print Publication: 2015).
    Typ publikacji:
    Clinical Trial; Comparative Study; Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Catheters, Indwelling*
    Amyloid beta-Peptides/*cerebrospinal fluid
    Peptide Fragments/*cerebrospinal fluid
    Spinal Puncture/*methods
    Adult ; Aged ; Alzheimer Disease/cerebrospinal fluid ; Analysis of Variance ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Linear Models ; Male ; Middle Aged ; Photoperiod ; Reproducibility of Results ; Spinal Puncture/instrumentation ; Time Factors ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    How amyloid, sleep and memory connect.
    Autorzy:
    Lucey BP; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, Missouri, USA.
    Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, Missouri, USA.
    Pokaż więcej
    Źródło:
    Nature neuroscience [Nat Neurosci] 2015 Jul; Vol. 18 (7), pp. 933-4.
    Typ publikacji:
    Journal Article; Comment
    MeSH Terms:
    Amyloid beta-Peptides/*metabolism
    Brain Waves/*physiology
    Hippocampus/*physiopathology
    Memory Disorders/*physiopathology
    Prefrontal Cortex/*metabolism
    Sleep Stages/*physiology
    Sleep Wake Disorders/*physiopathology
    Female ; Humans ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy.
    Autorzy:
    Lucey BP; Department of Neurology, Michael O'Callaghan Federal Hospital, Nellis Air Force Base, NV, USA. />Clifford DB
    Creighton J
    Edwards RR
    McArthur JC
    Haythornthwaite J
    Pokaż więcej
    Źródło:
    AIDS care [AIDS Care] 2011 Aug; Vol. 23 (8), pp. 921-8.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Catastrophization*
    Antiretroviral Therapy, Highly Active/*adverse effects
    Depression/*psychology
    Medication Adherence/*psychology
    Neuralgia/*psychology
    Adaptation, Psychological ; Adult ; Aged ; Chronic Disease/psychology ; Cross-Sectional Studies ; Female ; HIV Infections/complications ; HIV Infections/psychology ; Humans ; Male ; Middle Aged ; Pain Measurement ; Quality of Life/psychology ; Surveys and Questionnaires ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-17 z 17

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