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Tytuł :
The dual luciferase reporter system and RT-qPCR strategies for screening of MicroRNA-21 small-molecule inhibitors.
Autorzy :
Hei YY; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.
Guo YX; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, People's Republic of China.
Jiang CS; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, People's Republic of China.
Wang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, People's Republic of China.
Lu SM; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, People's Republic of China.
Zhang SQ; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.
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Źródło :
Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2019 Sep; Vol. 66 (5), pp. 755-762. Date of Electronic Publication: 2019 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Real-Time Polymerase Chain Reaction*
Genes, Reporter/*drug effects
Luciferases, Firefly/*antagonists & inhibitors
MicroRNAs/*pharmacology
Small Molecule Libraries/*pharmacology
Drug Evaluation, Preclinical ; Genes, Reporter/genetics ; HeLa Cells ; High-Throughput Screening Assays ; Humans ; Luciferases, Firefly/genetics ; Luciferases, Firefly/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Protonation status and control mechanism of flavin–oxygen intermediates in the reaction of bacterial luciferase.
Autorzy :
Tinikul, Ruchanok (AUTHOR)
Lawan, Narin (AUTHOR)
Akeratchatapan, Nattanon (AUTHOR)
Pimviriyakul, Panu (AUTHOR)
Chinantuya, Wachirawit (AUTHOR)
Suadee, Chutintorn (AUTHOR)
Sucharitakul, Jeerus (AUTHOR)
Chenprakhon, Pirom (AUTHOR)
Ballou, David P. (AUTHOR)
Entsch, Barrie (AUTHOR)
Chaiyen, Pimchai (AUTHOR)
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Źródło :
FEBS Journal. May2021, Vol. 288 Issue 10, p3246-3260. 15p.
Czasopismo naukowe
Tytuł :
Selection, drift, and constraint in cypridinid luciferases and the diversification of bioluminescent signals in sea fireflies.
Autorzy :
Hensley, Nicholai M. (AUTHOR)
Ellis, Emily A. (AUTHOR)
Leung, Nicole Y. (AUTHOR)
Coupart, John (AUTHOR)
Mikhailovsky, Alexander (AUTHOR)
Taketa, Daryl A. (AUTHOR)
Tessler, Michael (AUTHOR)
Gruber, David F. (AUTHOR)
De Tomaso, Anthony W. (AUTHOR)
Mitani, Yasuo (AUTHOR)
Rivers, Trevor J. (AUTHOR)
Gerrish, Gretchen A. (AUTHOR)
Torres, Elizabeth (AUTHOR)
Oakley, Todd H. (AUTHOR)
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Źródło :
Molecular Ecology. Apr2021, Vol. 30 Issue 8, p1864-1879. 16p.
Czasopismo naukowe
Tytuł :
miR-145 inhibits the proliferation and migration of vascular smooth muscle cells by regulating autophagy.
Autorzy :
Wang W; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Chen L; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Shang C; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jin Z; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yao F; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Bai L; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Wang R; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Zhao S; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
Liu E; Department of Medical Laboratory Animal Science, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.; Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Xi'an, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Jun; Vol. 24 (12), pp. 6658-6669. Date of Electronic Publication: 2020 Apr 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*/drug effects
Autophagy*/genetics
Cell Movement*/drug effects
Cell Movement*/genetics
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*pathology
Myocytes, Smooth Muscle/*cytology
Myocytes, Smooth Muscle/*metabolism
Animals ; Carotid Arteries/pathology ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Hyperplasia ; Luciferases/metabolism ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/ultrastructure ; Rats, Sprague-Dawley ; Sirtuins/metabolism ; Transforming Growth Factor beta1/pharmacology ; Tunica Intima/pathology
Czasopismo naukowe
Tytuł :
Nucleolin promotes Ang II-induced phenotypic transformation of vascular smooth muscle cells by regulating EGF and PDGF-BB.
Autorzy :
Fang L; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, China.; Department of Cardiology, The First Hospital of Changsha, Changsha, China.
Wang KK; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, China.
Zhang PF; Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Li T; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, China.
Xiao ZL; Department of Geriatric Cardiology, Xiangya Hospital, Central South University, Changsha, China.
Yang M; Department of Geriatric Cardiology, Xiangya Hospital, Central South University, Changsha, China.
Yu ZX; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Jan; Vol. 24 (2), pp. 1917-1933. Date of Electronic Publication: 2020 Jan 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*pharmacology
Becaplermin/*metabolism
Epidermal Growth Factor/*metabolism
Muscle, Smooth, Vascular/*cytology
Myocytes, Smooth Muscle/*metabolism
Phosphoproteins/*metabolism
RNA-Binding Proteins/*metabolism
5' Untranslated Regions/genetics ; Becaplermin/genetics ; Cell Line ; Cell Line, Transformed ; Epidermal Growth Factor/genetics ; Gene Expression Regulation ; Genes, Reporter ; Luciferases/metabolism ; Phenotype ; Protein Binding ; RNA Stability
Czasopismo naukowe
Tytuł :
Development and characterization of a novel, megakaryocyte NF‐κB reporter cell line for investigating inflammatory responses.
Autorzy :
Vallance, Thomas M. (AUTHOR)
Sheard, Jonathan J. (AUTHOR)
Meng, Yiming (AUTHOR)
Torre, Enrico C. (AUTHOR)
Patel, Ketan (AUTHOR)
Widera, Darius (AUTHOR)
Vaiyapuri, Sakthivel (AUTHOR)
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Źródło :
Journal of Thrombosis & Haemostasis. Jan2021, Vol. 19 Issue 1, p107-120. 14p. 1 Color Photograph, 2 Black and White Photographs, 4 Graphs.
Czasopismo naukowe
Tytuł :
An alternative approach in regulation of expression of a transgene by endogenous miR-145 in carcinoma and normal breast cell lines.
Autorzy :
Ghanbari Safari M; Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Baesi K; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Hosseinkhani S; Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
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Źródło :
Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2017 Mar; Vol. 64 (2), pp. 244-250.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Therapy*
Breast Neoplasms/*genetics
Luciferases, Renilla/*genetics
MicroRNAs/*biosynthesis
Breast Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Genetic Vectors ; Humans ; Luciferases, Renilla/biosynthesis ; MCF-7 Cells ; MicroRNAs/genetics ; Transgenes
Czasopismo naukowe
Tytuł :
Functional analysis of 5 upstream polymorphic variations of the human dopamine D1 receptor gene.
Autorzy :
Wu X; School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
Meng JH; School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
Xu FL; School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
Wang BJ; School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
Yao J; School of Forensic Medicine, China Medical University, Shenyang, P.R. China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Aug; Vol. 23 (8), pp. 5813-5817. Date of Electronic Publication: 2019 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Polymorphism, Single Nucleotide/*genetics
Receptors, Dopamine D1/*genetics
Alleles ; Biological Assay ; Cell Line, Tumor ; HEK293 Cells ; Humans ; Luciferases/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
LncRNA-SULT1C2A regulates Foxo4 in congenital scoliosis by targeting rno-miR-466c-5p through PI3K-ATK signalling.
Autorzy :
Chen C; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Tan H; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Bi J; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Li L; Beijing Zhongke Jingyun Technology Company Ltd., Beijing, China.
Rong T; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Lin Y; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Sun P; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.; Department of Orthopedics Surgery, Beijing Hospital of Traditional Chinese Medicine, Beijing, China.
Liang J; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Jiao Y; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Li Z; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Sun L; Beijing Zhongke Jingyun Technology Company Ltd., Beijing, China.
Shen J; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Jul; Vol. 23 (7), pp. 4582-4591. Date of Electronic Publication: 2019 May 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Forkhead Transcription Factors/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
RNA, Long Noncoding/*metabolism
Scoliosis/*congenital
Scoliosis/*genetics
3' Untranslated Regions/genetics ; Animals ; Base Sequence ; Down-Regulation/genetics ; Embryo, Mammalian/metabolism ; Forkhead Transcription Factors/genetics ; Gene Expression Regulation, Developmental ; Genes, Reporter ; HEK293 Cells ; Humans ; Luciferases/metabolism ; MicroRNAs ; Models, Biological ; Organogenesis/genetics ; RNA, Long Noncoding/genetics ; Rats, Sprague-Dawley ; Somites/embryology ; Vitamin A Deficiency/embryology ; Vitamin A Deficiency/genetics
Czasopismo naukowe
Tytuł :
PTH‐induced EndMT via miR‐29a‐5p/GSAP/Notch1 pathway contributed to valvular calcification in rats with CKD.
Autorzy :
Wang, Liting
Tang, Rining
Zhang, Yuxia
Chen, Sijie
Guo, Yu
Wang, Xiaochen
Liu, Zixiao
Liu, Hong
Zhang, Xiaoliang
Liu, Bi‐Cheng
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Temat :
RATS
CHRONIC kidney failure
CALCIFICATION
SCANNING electron microscopes
UMBILICAL veins
LUCIFERASES
Źródło :
Cell Proliferation; Jun2021, Vol. 54 Issue 6, p1-15, 15p
Czasopismo naukowe
Tytuł :
Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis.
Autorzy :
Wang N; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, China.
Li R; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, China.
Xue M; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Feb; Vol. 23 (2), pp. 852-864. Date of Electronic Publication: 2018 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Interleukin-1 Receptor Accessory Protein/*genetics
MicroRNAs/*genetics
Pre-Eclampsia/*genetics
RNA, Long Noncoding/*genetics
Trophoblasts/*metabolism
Adult ; Animals ; Case-Control Studies ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Hypoxia ; Cell Line, Transformed ; Cell Movement ; Cell Survival ; Female ; Gene Expression Regulation ; Genes, Reporter ; Humans ; Interleukin-1 Receptor Accessory Protein/metabolism ; Luciferases/genetics ; Luciferases/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Mice ; MicroRNAs/metabolism ; Pre-Eclampsia/metabolism ; Pre-Eclampsia/pathology ; Pregnancy ; RNA, Long Noncoding/metabolism ; Trophoblasts/pathology
Czasopismo naukowe
Tytuł :
A two-step culture method utilizing secreted luciferase recombinant virus for detection of anti-cytomegalovirus compounds.
Autorzy :
Koshizuka T; Department of Microbiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan.
Sato Y; Department of Microbiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan.
Kobiyama S; Department of Microbiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan.
Oshima M; Department of Microbiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan.
Suzutani T; Department of Microbiology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan.
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Źródło :
Microbiology and immunology [Microbiol Immunol] 2018 Oct; Vol. 62 (10), pp. 651-658.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*metabolism
Cytomegalovirus/*genetics
Cytomegalovirus/*metabolism
Luciferases/*genetics
Luciferases/*metabolism
Antiviral Agents/pharmacology ; Cell Line ; Chemokines, CXC/genetics ; Cytomegalovirus Infections/virology ; DNA Replication ; Epithelial Cells/virology ; Fibroblasts/virology ; Humans ; Membrane Glycoproteins/genetics ; Promoter Regions, Genetic/genetics ; Viral Envelope Proteins/genetics ; Viral Load ; Viral Proteins/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Autorzy :
Qin DD; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Yang YF; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Pu ZQ; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Liu D; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Yu C; Department of Life Science, Qilu Normal University, Jinan, China.
Gao P; Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, China.
Chen JC; Department of Blood Transfusion of Qilu Hospital, Shandong University, Jinan, China.
Zong C; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Zhang YC; Department of Endocrinology, Qingdao Municipal Hospital, Qingdao, China.
Li X; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Wang XD; Department of Cell Biology, Shandong University School of Medicine, Jinan, China.
Liu YT; Department of Endocrinology, Qingdao Municipal Hospital, Qingdao, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Oct; Vol. 22 (10), pp. 4709-4720. Date of Electronic Publication: 2018 Jul 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes/*metabolism
Adipogenesis/*genetics
GATA2 Transcription Factor/*genetics
Nuclear Receptor Subfamily 4, Group A, Member 1/*genetics
Obesity/*genetics
Tumor Suppressor Protein p53/*genetics
3T3-L1 Cells ; Adipocytes/cytology ; Animals ; Base Sequence ; Cell Differentiation/genetics ; Diet, High-Fat/adverse effects ; Fatty Acid Synthase, Type I/genetics ; Fatty Acid Synthase, Type I/metabolism ; GATA2 Transcription Factor/metabolism ; Gene Expression Regulation ; Genes, Reporter ; Lipid Metabolism/genetics ; Luciferases/genetics ; Luciferases/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nuclear Receptor Subfamily 4, Group A, Member 1/deficiency ; Obesity/etiology ; Obesity/metabolism ; Obesity/pathology ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Promoter Regions, Genetic ; Protein Binding ; Signal Transduction ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
MicroRNA-194 protects against chronic hepatitis B-related liver damage by promoting hepatocyte growth via ACVR2B.
Autorzy :
Gao X; Department of Pathology, 302 Hospital, Beijing, China.
Zhao P; Clinical Trial Center, Beijing 302 Hospital, Beijing, China.
Hu J; Liver Surgery Department, Zhongshan Hospital, Fudan University, Shanghai, China.; Liver Cancer Institute, Fudan University, Shanghai, China.
Zhu H; Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Zhang J; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhou Z; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
Zhao J; Department of Pathology, 302 Hospital, Beijing, China.
Tang F; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Sep; Vol. 22 (9), pp. 4534-4544. Date of Electronic Publication: 2018 Jul 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Activin Receptors, Type II/*genetics
Hepatitis B, Chronic/*genetics
Host-Pathogen Interactions/*genetics
Liver Regeneration/*genetics
MicroRNAs/*genetics
Activin Receptors, Type II/metabolism ; Animals ; Base Sequence ; Case-Control Studies ; Cell Cycle/genetics ; Cell Proliferation ; Cells, Cultured ; Gene Expression Regulation ; Genes, Reporter ; Hepatitis B virus/genetics ; Hepatitis B virus/pathogenicity ; Hepatitis B, Chronic/metabolism ; Hepatitis B, Chronic/pathology ; Hepatitis B, Chronic/virology ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Hepatocytes/virology ; Humans ; Liver/injuries ; Liver/metabolism ; Liver/virology ; Luciferases/genetics ; Luciferases/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/agonists ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Oligoribonucleotides/genetics ; Oligoribonucleotides/metabolism ; Signal Transduction ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
Knockdown of LINC01614 inhibits lung adenocarcinoma cell progression by up-regulating miR-217 and down-regulating FOXP1.
Autorzy :
Liu AN; Department of Medical Oncology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
Qu HJ; Department of Medical Oncology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
Yu CY; Department of Medical Oncology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
Sun P; Department of Medical Oncology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Sep; Vol. 22 (9), pp. 4034-4044. Date of Electronic Publication: 2018 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Adenocarcinoma of Lung/*genetics
Forkhead Transcription Factors/*genetics
Lung Neoplasms/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Repressor Proteins/*genetics
3' Untranslated Regions ; A549 Cells ; Adenocarcinoma of Lung/metabolism ; Adenocarcinoma of Lung/pathology ; Adenocarcinoma of Lung/surgery ; Apoptosis/genetics ; Base Sequence ; Cell Line, Tumor ; Cell Proliferation ; Forkhead Transcription Factors/metabolism ; Genes, Reporter ; Humans ; Luciferases/genetics ; Luciferases/metabolism ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; MicroRNAs/metabolism ; Oligoribonucleotides/genetics ; Oligoribonucleotides/metabolism ; RNA, Long Noncoding/antagonists & inhibitors ; RNA, Long Noncoding/metabolism ; Repressor Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Levamisole suppresses adipogenesis of aplastic anaemia-derived bone marrow mesenchymal stem cells through ZFP36L1-PPARGC1B axis.
Autorzy :
Liu LL; Central Laboratory, Affiliated Hospital of Jining Medical University, Jining, China.
Liu L; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Liu HH; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.; Department of Graduate School, Jining Medical University, Jining, China.
Ren SS; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Dou CY; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Cheng PP; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Wang CL; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Wang LN; Central Laboratory, Affiliated Hospital of Jining Medical University, Jining, China.
Chen XL; Department of Graduate School, Jining Medical University, Jining, China.
Zhang H; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China.
Chen MT; Central Laboratory, Affiliated Hospital of Jining Medical University, Jining, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Sep; Vol. 22 (9), pp. 4496-4506. Date of Electronic Publication: 2018 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes/*drug effects
Adipogenesis/*drug effects
Anemia, Aplastic/*genetics
Butyrate Response Factor 1/*genetics
Carrier Proteins/*genetics
Levamisole/*pharmacology
Mesenchymal Stem Cells/*drug effects
Adipocytes/metabolism ; Adipocytes/pathology ; Adipogenesis/genetics ; Adolescent ; Adult ; Anemia, Aplastic/metabolism ; Anemia, Aplastic/pathology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Bone Marrow Cells/pathology ; Butyrate Response Factor 1/agonists ; Butyrate Response Factor 1/metabolism ; Carrier Proteins/metabolism ; Case-Control Studies ; Cell Differentiation ; Female ; Gene Expression Regulation ; Genes, Reporter ; Humans ; Luciferases/genetics ; Luciferases/metabolism ; Male ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/pathology ; Middle Aged ; Primary Cell Culture ; RNA-Binding Proteins ; Signal Transduction
Czasopismo naukowe

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