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Wyszukujesz frazę ""Luckett, Jeni C."" wg kryterium: Autor


Wyświetlanie 1-13 z 13
Tytuł :
Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile .
Autorzy :
Karyal C; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Hughes J; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Kelly ML; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Luckett JC; The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Kaye PV; Department of Histopathology, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, UK.; National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre (BRC), Nottingham NG7 2UH, UK.
Cockayne A; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Minton NP; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
Griffin R; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.
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Źródło :
Microorganisms [Microorganisms] 2021 Feb 02; Vol. 9 (2). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
Autorzy :
John AE; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Graves RH; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Pun KT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Vitulli G; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Forty EJ; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Mercer PF; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Morrell JL; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Barrett JW; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Rogers RF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Hafeji M; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Bibby LI; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Gower E; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Morrison VS; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Man Y; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Roper JA; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Luckett JC; Radiological Sciences, University of Nottingham, Nottingham, UK.
Borthwick LA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Barksby BS; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Burgoyne RA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Barnes R; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Le J; Drug Design and Selection - Molecular Design, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Flint DJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Pyne S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Habgood A; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Organ LA; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Joseph C; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Edwards-Pritchard RC; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Maher TM; NIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.; Fibrosis Research Group, National Heart and Lung Institute, Imperial College, London, UK.
Fisher AJ; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS, Foundation Trust, Newcastle upon Tyne, UK.
Gudmann NS; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark.
Leeming DJ; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark.
Chambers RC; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Lukey PT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Marshall RP; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Macdonald SJF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Jenkins RG; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK. .
Slack RJ; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
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Źródło :
Nature communications [Nat Commun] 2020 Sep 16; Vol. 11 (1), pp. 4659. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Butyrates/*pharmacology
Idiopathic Pulmonary Fibrosis/*drug therapy
Integrins/*antagonists & inhibitors
Naphthyridines/*pharmacology
Pyrazoles/*pharmacology
Pyrrolidines/*pharmacology
Administration, Inhalation ; Animals ; Antigens, Neoplasm/metabolism ; Bleomycin/toxicity ; Butyrates/administration & dosage ; Butyrates/metabolism ; Butyrates/pharmacokinetics ; Collagen/metabolism ; Disease Models, Animal ; Epithelial Cells/drug effects ; Humans ; Idiopathic Pulmonary Fibrosis/chemically induced ; Idiopathic Pulmonary Fibrosis/pathology ; Integrins/metabolism ; Male ; Mice, Inbred C57BL ; Molecular Docking Simulation ; Naphthyridines/administration & dosage ; Naphthyridines/metabolism ; Naphthyridines/pharmacokinetics ; Pyrazoles/administration & dosage ; Pyrazoles/metabolism ; Pyrazoles/pharmacokinetics ; Pyrrolidines/administration & dosage ; Pyrrolidines/metabolism ; Pyrrolidines/pharmacokinetics ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Tomography, Emission-Computed, Single-Photon ; Transforming Growth Factor beta/metabolism ; Translational Medical Research
Czasopismo naukowe
Tytuł :
Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo
Autorzy :
Rostam, Hassan M.
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Źródło :
In Matter 3 June 2020 2(6):1564-1581
Czasopismo naukowe
Tytuł :
Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice.
Autorzy :
Lewis JE; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Samms RJ; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Cooper S; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Luckett JC; School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Perkins AC; School of Medicine, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Dunbar JD; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Smith DP; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Emmerson PJ; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Adams AC; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Ebling FJP; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Tsintzas K; School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
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Źródło :
Endocrinology [Endocrinology] 2017 Oct 01; Vol. 158 (10), pp. 3090-3096.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue, Brown/*metabolism
Adipose Tissue, White/*metabolism
Antibodies, Monoclonal/*administration & dosage
Receptor, Fibroblast Growth Factor, Type 1/*antagonists & inhibitors
Acetyl-CoA Carboxylase/metabolism ; Animals ; Antibodies, Monoclonal/therapeutic use ; Blood Glucose/analysis ; Brain/drug effects ; Brain/metabolism ; Enzyme Activation/drug effects ; Glucose/metabolism ; Insulin/pharmacology ; Lipase/analysis ; Liver/drug effects ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Obesity/metabolism ; Protein Isoforms ; Receptor, Fibroblast Growth Factor, Type 1/immunology ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.
Autorzy :
Lewis JE; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK. .
Samms RJ; Lilly Research Laboratories, Indianapolis, IN, 46285, USA.
Cooper S; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Luckett JC; Radiological Sciences, School of Medicine, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Perkins AC; Radiological Sciences, School of Medicine, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Adams AC; Lilly Research Laboratories, Indianapolis, IN, 46285, USA.
Tsintzas K; MRC/ARUK Centre for Musculoskeletal Ageing, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Ebling FJP; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
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Źródło :
Scientific reports [Sci Rep] 2017 Jun 26; Vol. 7 (1), pp. 4238. Date of Electronic Publication: 2017 Jun 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adiposity/*genetics
Fibroblast Growth Factors/*genetics
Obesity/*genetics
Phodopus/*genetics
Adipose Tissue/physiology ; Adiposity/physiology ; Animals ; Body Weight ; Circadian Rhythm/genetics ; Cricetinae ; Energy Metabolism/genetics ; Humans ; Obesity/physiopathology ; Phodopus/physiology ; Photoperiod ; Seasons
Czasopismo naukowe
Tytuł :
Antibody-Mediated Inhibition of the FGFR1c Isoform Induces a Catabolic Lean State in Siberian Hamsters.
Autorzy :
Samms RJ; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK; Lilly Research Laboratories, Indianapolis, IN 46285, USA.
Lewis JE; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Lory A; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Fowler MJ; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Cooper S; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Warner A; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Emmerson P; Lilly Research Laboratories, Indianapolis, IN 46285, USA.
Adams AC; Lilly Research Laboratories, Indianapolis, IN 46285, USA.
Luckett JC; School of Medicine, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Perkins AC; School of Medicine, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Wilson D; Rowett Institute for Nutrition and Health, University of Aberdeen, Greenburn Road, Aberdeen AB21 9SB, UK.
Barrett P; Rowett Institute for Nutrition and Health, University of Aberdeen, Greenburn Road, Aberdeen AB21 9SB, UK.
Tsintzas K; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Ebling FJ; School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK. Electronic address: .
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Źródło :
Current biology : CB [Curr Biol] 2015 Nov 16; Vol. 25 (22), pp. 2997-3003. Date of Electronic Publication: 2015 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*pharmacology
Eating/*drug effects
Receptor, Fibroblast Growth Factor, Type 1/*antagonists & inhibitors
Adiposity/physiology ; Animals ; Antibodies, Monoclonal/immunology ; Circadian Rhythm/physiology ; Cricetinae ; Hypothalamus/metabolism ; Male ; Models, Animal ; Phodopus ; Photoperiod ; Protein Isoforms/metabolism ; Receptor, Fibroblast Growth Factor, Type 1/immunology ; Receptor, Fibroblast Growth Factor, Type 1/metabolism ; Thinness/metabolism ; Thyroid Hormones/metabolism ; Weight Loss/drug effects
Czasopismo naukowe
Tytuł :
Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis.
Autorzy :
John AE; Nottingham Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.
Luckett JC
Tatler AL
Awais RO
Desai A
Habgood A
Ludbrook S
Blanchard AD
Perkins AC
Jenkins RG
Marshall JF
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2013 Dec; Vol. 54 (12), pp. 2146-52. Date of Electronic Publication: 2013 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Multimodal Imaging*
Tomography, Emission-Computed, Single-Photon*
Tomography, X-Ray Computed*
Antigens, Neoplasm/*metabolism
Idiopathic Pulmonary Fibrosis/*diagnostic imaging
Integrins/*metabolism
Animals ; Antigens, Neoplasm/genetics ; Biomarkers/metabolism ; Endpoint Determination ; Idiopathic Pulmonary Fibrosis/metabolism ; Idiopathic Pulmonary Fibrosis/pathology ; Indium Radioisotopes ; Integrins/genetics ; Lung/diagnostic imaging ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Peptides ; Prognosis ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Properdin deficiency in murine models of nonseptic shock.
Autorzy :
Ivanovska ND; Department of Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Dimitrova PA
Luckett JC
El-Rachkidy Lonnen R
Schwaeble WJ
Stover CM
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2008 May 15; Vol. 180 (10), pp. 6962-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipopolysaccharides/*toxicity
Properdin/*deficiency
Shock/*metabolism
Shock/*physiopathology
Zymosan/*toxicity
Animals ; Complement C5a/metabolism ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique ; Interleukin-10/metabolism ; Macrophage Activation/immunology ; Macrophages/immunology ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Nitric Oxide/biosynthesis ; Shock/chemically induced ; Tumor Necrosis Factor-alpha/metabolism ; alpha 1-Antitrypsin/blood
Czasopismo naukowe
Tytuł :
Properdin plays a protective role in polymicrobial septic peritonitis.
Autorzy :
Stover CM; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK. />Luckett JC
Echtenacher B
Dupont A
Figgitt SE
Brown J
Männel DN
Schwaeble WJ
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2008 Mar 01; Vol. 180 (5), pp. 3313-8.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Peritonitis/*immunology
Peritonitis/*prevention & control
Properdin/*physiology
Sepsis/*immunology
Sepsis/*prevention & control
Animals ; Cecum ; Complement C3/metabolism ; Complement Pathway, Alternative/immunology ; Escherichia coli Infections/immunology ; Escherichia coli Infections/metabolism ; Escherichia coli Infections/prevention & control ; Escherichia coli K12/immunology ; Female ; Ligation ; Male ; Mast Cells/immunology ; Mast Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Mice, Knockout ; Peritonitis/metabolism ; Properdin/deficiency ; Properdin/genetics ; Punctures ; Sepsis/metabolism
Czasopismo naukowe
Tytuł :
Ex vivo cancer chemoprevention research possibilities.
Autorzy :
Hudson EA; Cancer Biomarkers and Prevention Group, Departments of Biochemistry and Cancer Studies and Molecular Medicine, Biocentre, University of Leicester, Leicester LE1 7RH, UK.
Fox LH
Luckett JC
Manson MM
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Źródło :
Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2006 Feb; Vol. 21 (2), pp. 204-14. Date of Electronic Publication: 2005 Aug 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
    Wyświetlanie 1-13 z 13

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