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Tytuł:
Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients.
Autorzy:
Coudereau R; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, 69437 Lyon, France.; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-Biomérieux, 69437 Lyon, France.
Monneret G; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, 69437 Lyon, France.; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-Biomérieux, 69437 Lyon, France.
Lukaszewicz AC; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-Biomérieux, 69437 Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Anesthesia and Critical Care Medicine Department, 69437 Lyon, France.
Py BF; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
Argaud L; Hospices Civils de Lyon, Edouard Herriot Hospital, Medical Intensive Care Department, 69002 Lyon, France.
Cour M; Hospices Civils de Lyon, Edouard Herriot Hospital, Medical Intensive Care Department, 69002 Lyon, France.
Bidar F; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-Biomérieux, 69437 Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Anesthesia and Critical Care Medicine Department, 69437 Lyon, France.
Gossez M; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, 69437 Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
Venet F; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, 69437 Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
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Źródło:
Viruses [Viruses] 2023 Dec 13; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammasomes*/metabolism
Sepsis*/mortality
Humans ; Caspase 1/metabolism ; Longitudinal Studies ; Nigericin ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of pronounced elevation of NET formation and nucleosome biomarkers with mortality in patients with septic shock.
Autorzy:
Haem Rahimi M; Hospices Civils de Lyon, Guillaume Monneret - Immunology Laboratory, Hôpital E. Herriot, Lyon, France.; Université de Lyon, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon_1, Lyon, France.
Bidar F; Hospices Civils de Lyon, Anesthesiology and Critical Care Medicine Department, Hôpital E. Herriot, Lyon, France.
Lukaszewicz AC; Université de Lyon, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon_1, Lyon, France.; Hospices Civils de Lyon, Anesthesiology and Critical Care Medicine Department, Hôpital E. Herriot, Lyon, France.
Garnier L; Hospices Civils de Lyon, Immunology Laboratory, CH Lyon-Sud, Lyon, France.
Payen-Gay L; Center for Innovation in Cancerology of Lyon (CICLY) EA 3738, Faculty of Medicine and Maieutic Lyon Sud, Claude Bernard University Lyon I, 69921, Oullins, France.
Venet F; Hospices Civils de Lyon, Guillaume Monneret - Immunology Laboratory, Hôpital E. Herriot, Lyon, France.; NLRP3 Inflammation and Immune Response to Sepsis Team, Centre International de Recherche in Infectiology (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Claude Bernard University Lyon 1, Lyon, France.
Monneret G; Hospices Civils de Lyon, Guillaume Monneret - Immunology Laboratory, Hôpital E. Herriot, Lyon, France. .; Université de Lyon, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon_1, Lyon, France. .
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Źródło:
Annals of intensive care [Ann Intensive Care] 2023 Oct 17; Vol. 13 (1), pp. 102. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dysregulated expression of amino-acid and glucose transporters on circulating plasma cells in septic shock patients: a preliminary study.
Autorzy:
Lepage M; Immunology Laboratory, Hôpital E. Herriot, Hospices Civils de Lyon, Edouard Herriot Hospital, 5 Place d'Arsonval, 69437, Lyon Cedex 03, France.; Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard-Lyon 1, Lyon, France.
Gossez M; Immunology Laboratory, Hôpital E. Herriot, Hospices Civils de Lyon, Edouard Herriot Hospital, 5 Place d'Arsonval, 69437, Lyon Cedex 03, France.; Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard-Lyon 1, Lyon, France.
Lukaszewicz AC; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1, Hospices Civils de Lyon, bioMérieux), Edouard Herriot Hospital, 69437, Lyon, France.; Anaesthesia and Critical Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.; Joint Research Unit HCL-bioMérieux, Hôpital Edouard Herriot, 5 Place d'Arsonval, 69003, Lyon, France.
Monneret G; Immunology Laboratory, Hôpital E. Herriot, Hospices Civils de Lyon, Edouard Herriot Hospital, 5 Place d'Arsonval, 69437, Lyon Cedex 03, France.; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1, Hospices Civils de Lyon, bioMérieux), Edouard Herriot Hospital, 69437, Lyon, France.; Joint Research Unit HCL-bioMérieux, Hôpital Edouard Herriot, 5 Place d'Arsonval, 69003, Lyon, France.
Venet F; Immunology Laboratory, Hôpital E. Herriot, Hospices Civils de Lyon, Edouard Herriot Hospital, 5 Place d'Arsonval, 69437, Lyon Cedex 03, France. .; Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard-Lyon 1, Lyon, France. .
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Źródło:
Intensive care medicine experimental [Intensive Care Med Exp] 2022 Oct 31; Vol. 10 (1), pp. 44. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Letter
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Monitoring NLRP3 Inflammasome Activation and Exhaustion in Clinical Samples: A Refined Flow Cytometry Protocol for ASC Speck Formation Measurement Directly in Whole Blood after Ex Vivo Stimulation.
Autorzy:
Coudereau R; Immunology Laboratory, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d'Arsonval, CEDEX 03, 69437 Lyon, France.; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, 69003 Lyon, France.
Gossez M; Immunology Laboratory, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d'Arsonval, CEDEX 03, 69437 Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
Py BF; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
Henry T; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
Lukaszewicz AC; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, 69003 Lyon, France.; Anaesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d'Arsonval, CEDEX 03, 69437 Lyon, France.
Monneret G; Immunology Laboratory, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d'Arsonval, CEDEX 03, 69437 Lyon, France.; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, 69003 Lyon, France.
Venet F; Immunology Laboratory, Edouard Herriot Hospital, Hospices Civils de Lyon, 5 Place d'Arsonval, CEDEX 03, 69437 Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
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Źródło:
Cells [Cells] 2022 Oct 20; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Humans ; Flow Cytometry/methods ; CARD Signaling Adaptor Proteins/metabolism ; Lipopolysaccharides ; Nigericin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score.
Autorzy:
Tremblay JA; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France. .; Critical Care Service, Hôpital Maisonneuve-Rosemont, 5415 Boulevard de l'Assomption, Montréal, H1T2M4, Canada. .
Peron F; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.
Kreitmann L; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.
Textoris J; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.
Brengel-Pesce K; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.
Lukaszewicz AC; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Quemeneur L; Sanofi Pasteur, Sanofi 1541 avenue Marcel Mérieux, 69280, Marcy l'Etoile, France.
Vedrine C; BIOASTER, 40 Avenue Tony Garnier, 69007, Lyon, France.
Tan LK; GSK, 980 Great West Road, Brentford, Middlesex, TW8 9GS, UK.
Venet F; Immunology Laboratory, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Team 'NLRP3 Inflammation and Immune Response to Sepsis', Université Claude Bernard-Lyon 1, Lyon, France.
Rimmele T; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Monneret G; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Joint Research Unit HCL-bioMérieux, Herriot Hospital, 5 place d'Arsonval, 69003, Lyon, France.; Immunology Laboratory, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
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Corporate Authors:
REALISM study group
Źródło:
Annals of intensive care [Ann Intensive Care] 2022 Aug 17; Vol. 12 (1), pp. 76. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Monitoring of circulating monocyte HLA-DR expression in a large cohort of intensive care patients: relation with secondary infections.
Autorzy:
de Roquetaillade C; Anesthesiology and Critical Care Unit, Hopital Lariboisière, Paris, France. .; INSERM U942, Département MASCOT, 43 Boulevard de la Chapelle, 75010, Paris, France. .
Dupuis C; Medical Intensive Care Unit, Clermont-Ferrand University Hospital, 58 rue Montalembert, 63003, Clermont-Ferrand, France.
Faivre V; Anesthesiology Laboratory, Hospital Lariboisière, Paris, France.
Lukaszewicz AC; Anesthesia & Critical Care, Hospital Neurologique, Hospices Civils de Lyon, EA 7426: Pathophysiology of Injury-Induced Immunosuppression (PI3), Université de Lyon 1, Lyon, France.
Brumpt C; Service d'Hématologie Biologique, Pôle B2P, Hôpital Lariboisière, APHP, Paris, France.
Payen D; Université Paris 7 UFR de Médecine, 110 A venue de Verdun, 75010, Paris, France.
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Źródło:
Annals of intensive care [Ann Intensive Care] 2022 May 08; Vol. 12 (1), pp. 39. Date of Electronic Publication: 2022 May 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Correction to: Recombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patients.
Autorzy:
Bidar F; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Hamada S; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Gossez M; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude, Bernard-Lyon 1, Lyon, France.
Coudereau R; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Lopez J; Biochemistry and Molecular Biology Laboratory, Lyon-Sud University Hospital-Hospices Civils de Lyon, Chemin du Grand Revoyet, Pierre-Benite, France.
Cazalis MA; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Tardiveau C; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Brengel-Pesce K; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Mommert M; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Buisson M; Centre d'Investigation Clinique de Lyon (CIC 1407 Inserm), Hospices Civils de Lyon, 69677, Lyon, France.
Conti F; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Rimmelé T; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.
Lukaszewicz AC; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.
Argaud L; Medical Intensive Care Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Cour M; Medical Intensive Care Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Monneret G; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Venet F; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France. .; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude, Bernard-Lyon 1, Lyon, France. .
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Corporate Authors:
RICO Study Group
Źródło:
Annals of intensive care [Ann Intensive Care] 2022 Apr 01; Vol. 12 (1), pp. 30. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patients.
Autorzy:
Bidar F; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Hamada S; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Gossez M; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude, Bernard-Lyon 1, Lyon, France.
Coudereau R; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Lopez J; Biochemistry and Molecular Biology Laboratory, Lyon-Sud University Hospital-Hospices Civils de Lyon, Chemin du Grand Revoyet, Pierre-Benite, France.
Cazalis MA; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Tardiveau C; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Brengel-Pesce K; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Mommert M; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Buisson M; Centre d'Investigation Clinique de Lyon (CIC 1407 Inserm), Hospices Civils de Lyon, 69677, Lyon, France.
Conti F; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.
Rimmelé T; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.
Lukaszewicz AC; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Anesthesia and Critical Care Medicine Department, Edouard Herriot Hospital, Hospices Civils de Lyon, 69437, Lyon, France.
Argaud L; Medical Intensive Care Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Cour M; Medical Intensive Care Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
Monneret G; Joint Research Unit HCL-bioMérieux, EA 7426 'Pathophysiology of Injury-Induced Immunosuppression', Université Claude Bernard Lyon, 1-Hospices Civils de Lyon-bioMérieux, 69003, Lyon, France.; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.
Venet F; Immunology Laboratory, Hôpital E. Herriot-Hospices Civils de Lyon, 5 place d'Arsonval, 69437, Lyon Cedex 03, France. .; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude, Bernard-Lyon 1, Lyon, France. .
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Corporate Authors:
RICO Study Group
Źródło:
Annals of intensive care [Ann Intensive Care] 2022 Mar 05; Vol. 12 (1), pp. 21. Date of Electronic Publication: 2022 Mar 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries-Insights from the REALISM Study.
Autorzy:
Bidar F; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.; Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, 69003 Lyon, France.; Immunology Laboratory, Hopital E. Herriot, Hospices Civils de Lyon, 69437 Lyon, France.
Bodinier M; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.
Venet F; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.; Immunology Laboratory, Hopital E. Herriot, Hospices Civils de Lyon, 69437 Lyon, France.; NLRP3 Inflammation and Immune Response to Sepsis Team, Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard-Lyon 1, 69003 Lyon, France.
Lukaszewicz AC; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.; Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, 69003 Lyon, France.
Brengel-Pesce K; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.
Conti F; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.
Quemeneur L; Sanofi Pasteur, Sanofi 1541 Avenue Marcel Mérieux, 69280 Marcy l'Etoile, France.
Leissner P; BIOASTER, 40 Avenue Tony Garnier, 69007 Lyon, France.
Tan LK; GSK, 980 Great West Road, Brentford, Middlesex TW8 9GS, UK.
Textoris J; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.
Rimmelé T; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.; Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, 69003 Lyon, France.
Monneret G; EA 7426 'Pathophysiology of Injury-Induced Immunosuppression' (Université Claude Bernard Lyon 1-Hospices Civils de Lyon-bioMérieux), Joint Research Unit HCL-bioMérieux, Univeristé Lyon 1, 69003 Lyon, France.; Immunology Laboratory, Hopital E. Herriot, Hospices Civils de Lyon, 69437 Lyon, France.
On Behalf Of The Realism Study Group
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Źródło:
Journal of clinical medicine [J Clin Med] 2021 Dec 24; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DAMPs and RAGE Pathophysiology at the Acute Phase of Brain Injury: An Overview.
Autorzy:
Balança B; Department of Neurological Anesthesiology and Intensive Care Medicine, Hospices Civils de Lyon, Hôpital Pierre Wertheimer, 69500 Bron, France.; Team TIGER, Lyon Neuroscience Research Centre, Inserm U1028, CNRS UMR 5292, 69500 Bron, France.
Desmurs L; Clinical Chemistry and Molecular Biology Laboratory, Hospices Civils de Lyon, Hôpital Pierre Wertheimer, 69500 Bron, France.
Grelier J; Department of Neurological Anesthesiology and Intensive Care Medicine, Hospices Civils de Lyon, Hôpital Pierre Wertheimer, 69500 Bron, France.
Perret-Liaudet A; Clinical Chemistry and Molecular Biology Laboratory, Hospices Civils de Lyon, Hôpital Pierre Wertheimer, 69500 Bron, France.; Team BIORAN, Lyon Neuroscience Research Centre, Inserm U1028, CNRS UMR 5292, 69500 Bron, France.
Lukaszewicz AC; Department of Neurological Anesthesiology and Intensive Care Medicine, Hospices Civils de Lyon, Hôpital Edouard Herriot, 69003 Lyon, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 28; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alarmins/*metabolism
Brain Injuries/*physiopathology
Glycation End Products, Advanced/*metabolism
Acute Disease ; Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Multicentric experience with interferon gamma therapy in sepsis induced immunosuppression. A case series.
Autorzy:
Payen D; Groupe Hospitalier Saint-Louis Lariboisière, AP-HP, Université Paris 7 Denis Diderot, 2 rue Ambroise Paré, 75010, Paris, France. .; UMR INSERM 1160 University Paris 7 Denis Diderot, Paris, France. .
Faivre V; Groupe Hospitalier Saint-Louis Lariboisière, AP-HP, Université Paris 7 Denis Diderot, 2 rue Ambroise Paré, 75010, Paris, France.; UMR INSERM 1160 University Paris 7 Denis Diderot, Paris, France.
Miatello J; Pediatric Intensive Care and Neonatal Medicine, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre, France.; Institute of Integrative Biology of Cell, CNRS, CEA, Univ. Paris Sud, Paris Saclay University, Gif sur Yvette, France.
Leentjens J; Departments of intensive care and internal medicine, Radboud university medical center Nijmegen, PO box 9101, 6500 HB, Nijmegen, The Netherlands.
Brumpt C; Service d'Hématologie Biologique, Pôle B2P, Hôpital Lariboisière, APHP, Paris, France.
Tissières P; Pediatric Intensive Care and Neonatal Medicine, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre, France.; Institute of Integrative Biology of Cell, CNRS, CEA, Univ. Paris Sud, Paris Saclay University, Gif sur Yvette, France.
Dupuis C; Groupe Hospitalier Saint-Louis Lariboisière, AP-HP, Université Paris 7 Denis Diderot, 2 rue Ambroise Paré, 75010, Paris, France.
Pickkers P; Department Intensive Care Medicine, Radboud university medical center Nijmegen, PO box 9101, 6500 HB, Nijmegen, The Netherlands.
Lukaszewicz AC; Groupe Hospitalier Saint-Louis Lariboisière, AP-HP, Université Paris 7 Denis Diderot, 2 rue Ambroise Paré, 75010, Paris, France.; UMR INSERM 1160 University Paris 7 Denis Diderot, Paris, France.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2019 Nov 05; Vol. 19 (1), pp. 931. Date of Electronic Publication: 2019 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Tolerance*
Interferon-gamma/*therapeutic use
Sepsis/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Child ; Female ; HLA-DR Antigens/metabolism ; Humans ; Infant ; Intensive Care Units ; Interleukin-10/blood ; Interleukin-6/blood ; Killer Cells, Natural/cytology ; Killer Cells, Natural/metabolism ; Male ; Middle Aged ; Monocytes/cytology ; Monocytes/metabolism ; Prospective Studies ; Pseudomonas aeruginosa/isolation & purification ; Sepsis/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients.
Autorzy:
Dubois C; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Marcé D; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Faivre V; Université Paris 7 Cité Sorbonne; UMR INSERM 1160, 110 Avenue de Verdun, Paris, 75010, France.; Department of Anesthesiology & Critical Care, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris (AP-HP), Paris, 75010, France.
Lukaszewicz AC; Université Paris 7 Cité Sorbonne; UMR INSERM 1160, 110 Avenue de Verdun, Paris, 75010, France.; Department of Anesthesiology & Critical Care, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris (AP-HP), Paris, 75010, France.
Junot C; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Fenaille F; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Simon S; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Becher F; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France.
Morel N; Service de Pharmacologie et Immunoanalyse (SPI), CEA, INRA, Université Paris-Saclay, Gif-sur Yvette, 91191, France. .
Payen D; Université Paris 7 Cité Sorbonne; UMR INSERM 1160, 110 Avenue de Verdun, Paris, 75010, France. .; Department of Anesthesiology & Critical Care, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris (AP-HP), Paris, 75010, France. .
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Źródło:
Scientific reports [Sci Rep] 2019 Oct 30; Vol. 9 (1), pp. 15660. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Patient Admission*
Calgranulin A/*blood
Calgranulin B/*blood
S100A12 Protein/*blood
Shock, Septic/*blood
Shock, Septic/*mortality
Adult ; Aged ; Female ; Humans ; Leukocyte L1 Antigen Complex/blood ; Male ; Middle Aged ; Prognosis ; Risk ; Shock, Septic/diagnosis ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Postoperative lymphopenia: An independent risk factor for postoperative pneumonia after lung cancer surgery, results of a case-control study.
Autorzy:
Dupont G; Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Saint-Étienne, Avenue Albert Raimond, France.; EA 7426 PI3-Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 / HCL / bioMérieux), Hôpital E., France.
Flory L; Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Saint-Étienne, Avenue Albert Raimond, France.
Morel J; Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Saint-Étienne, Avenue Albert Raimond, France.
Lukaszewicz AC; EA 7426 PI3-Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 / HCL / bioMérieux), Hôpital E., France.; Service d'Anesthésie Réanimation, Groupement Hospitalier Est, Hôpital Neurologique Pierre Wertheimer, France.
Patoir A; Département de chirurgie thoracique, Centre Hospitalier Universitaire de Saint-Etienne, France.
Presles E; Inserm, CIC1408, France.; CHU Saint-Etienne, Hôpital Nord, Service Unité de Recherche Clinique, Innovation et Pharmacologie, Saint-Etienne, France.
Monneret G; EA 7426 PI3-Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 / HCL / bioMérieux), Hôpital E., France.; Hospices Civils de Lyon, Laboratoire d'immunologie, Hôpital E Herriot, Lyon, France.
Molliex S; Département d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Saint-Étienne, Avenue Albert Raimond, France.
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Źródło:
PloS one [PLoS One] 2018 Oct 15; Vol. 13 (10), pp. e0205237. Date of Electronic Publication: 2018 Oct 15 (Print Publication: 2018).
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms/*surgery
Lymphopenia/*epidemiology
Pneumonectomy/*adverse effects
Pneumonia/*epidemiology
Postoperative Complications/*epidemiology
Aged ; Case-Control Studies ; Female ; Humans ; Lung/surgery ; Lymphocyte Count ; Lymphopenia/blood ; Lymphopenia/etiology ; Male ; Middle Aged ; Odds Ratio ; Pneumonectomy/methods ; Pneumonia/etiology ; Postoperative Complications/etiology ; Postoperative Period ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Platelet activation and aggregation after aneurysmal subarachnoid hemorrhage.
Autorzy:
Perez P; Anesthesiology and Critical Care Department, Lariboisière Hospital, Paris, France.
Lukaszewicz AC; Anesthesiology and Critical Care Department, Lariboisière Hospital, Paris, France. .; Inserm U1160, Lariboisière Hospital, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France. .
Lenck S; Department of Neuroradiology, Lariboisière Hospital, Paris, France.
Nizard R; Department of Orthopedic Surgery and Traumatology, Lariboisière Hospital, Paris, France.
Drouet L; Angio-Hematology Department (L.D.), Lariboisière Hospital, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.
Payen D; Anesthesiology and Critical Care Department, Lariboisière Hospital, Paris, France.; Inserm U1160, Lariboisière Hospital, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.
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Źródło:
BMC neurology [BMC Neurol] 2018 Apr 28; Vol. 18 (1), pp. 57. Date of Electronic Publication: 2018 Apr 28.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation*
Subarachnoid Hemorrhage/*blood
Subarachnoid Hemorrhage/*complications
Aged ; Blood Platelets ; Endovascular Procedures/adverse effects ; Endovascular Procedures/methods ; Female ; Humans ; Male ; Middle Aged ; Subarachnoid Hemorrhage/therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prone positioning in acute respiratory distress syndrome after abdominal surgery: a multicenter retrospective study : SAPRONADONF (Study of Ards and PRONe position After abDOmiNal surgery in France).
Autorzy:
Gaudry S; Medico-Surgical Intensive Care Unit, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.; Sorbonne Paris Cité, ECEVE UMR 1123, Univ Paris Diderot, 75018, Paris, France.
Tuffet S; Medico-Surgical Intensive Care Unit, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.; Département d'Anesthésie Réanimation, Hôpital Lariboisière, AP-HP, 75010, Paris, France.; UMR U 1160, Université Paris-Diderot Paris 7, 75010, Paris, France.
Lukaszewicz AC; Département d'Anesthésie Réanimation, Hôpital Lariboisière, AP-HP, 75010, Paris, France.; UMR U 1160, Université Paris-Diderot Paris 7, 75010, Paris, France.
Laplace C; Département d'Anesthésie Réanimation, Hôpital Bicêtre, AP-HP, 94270, Le Kremlin-Bicêtre, France.
Zucman N; Medico-Surgical Intensive Care Unit, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.
Pocard M; Hôpital Lariboisière, Chirurgie digestive et cancérologique, AP-HP, 75010, Paris, France.; UMR U 965, Université Paris-Diderot Paris 7, 75010, Paris, France.
Costaglioli B; Hôpital Bicêtre, Chirurgie générale et digestive, AP-HP, 94270, Le Kremlin-Bicêtre, France.
Msika S; Hôpital Louis Mourier, Chirurgie digestive, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.; UMR 1149, Univ Paris Diderot, Sorbonne Paris Cité, 75018, Paris, France.
Duranteau J; Département d'Anesthésie Réanimation, Hôpital Bicêtre, AP-HP, 94270, Le Kremlin-Bicêtre, France.
Payen D; Département d'Anesthésie Réanimation, Hôpital Lariboisière, AP-HP, 75010, Paris, France.; UMR U 1160, Université Paris-Diderot Paris 7, 75010, Paris, France.
Dreyfuss D; Medico-Surgical Intensive Care Unit, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.; IAME,UMR 1137, INSERM, 75018, Paris, France.; IAME, UMR 1137, Univ Paris Diderot, Sorbonne Paris Cité, 75018, Paris, France.
Hajage D; Sorbonne Paris Cité, ECEVE UMR 1123, Univ Paris Diderot, 75018, Paris, France.; Epidemiology and Clinical Research Department, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France.
Ricard JD; Medico-Surgical Intensive Care Unit, Hôpital Louis Mourier, AP-HP, 178 rue des Renouillers, 92700, Colombes, France. .; IAME,UMR 1137, INSERM, 75018, Paris, France. .; IAME, UMR 1137, Univ Paris Diderot, Sorbonne Paris Cité, 75018, Paris, France. .; Service de Réanimation Médicale, 178 rue des Renouillers, 92701, Colombes Cedex, France. .
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Źródło:
Annals of intensive care [Ann Intensive Care] 2017 Dec; Vol. 7 (1), pp. 21. Date of Electronic Publication: 2017 Feb 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 31

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