The lymphatic system is a complex of capillaries, ducts, nodes, and organs that filters and maintains interstitial fluid—that is, fluid from body tissues. Fluid is collected from body tissues and returned to the bloodstream. In addition, the system functions as a site of the immune response, primarily in the spleen and the lymph nodes, and transports fat and protein to the bloodstream.
LymphaticSystem and the Kidney: From Lymphangiogenesis to Renal Inflammation and Fibrosis Development.
Autorzy:
Stasi E; University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, ASL Città di Torino and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy. Sciascia S; University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, ASL Città di Torino and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy. Naretto C; University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, ASL Città di Torino and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy. Baldovino S; University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, ASL Città di Torino and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy. Roccatello D; University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, ASL Città di Torino and Department of Clinical and Biological Sciences, University of Turin, 10154 Turin, Italy.
Glymphatic and lymphatic communication with systemic responses during physiological and pathological conditions in the central nervous system.
Autorzy:
Licastro E; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Division of Pharmacology, Department of Neuroscience, School of Medicine, University 'Federico II', Naples, Italy. Pignataro G; Division of Pharmacology, Department of Neuroscience, School of Medicine, University 'Federico II', Naples, Italy. Iliff JJ; Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA. Xiang Y; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Department of Pharmacy, Qilu Hospital of Shandong University, Jinan, Shandong, China. Lo EH; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA), Radcliffe Department of Medicine, University of Oxford, Headington, Oxford, UK. Hayakawa K; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. . Esposito E; Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. .; Consortium International pour la Recherche Circadienne sur l'AVC (CIRCA), Radcliffe Department of Medicine, University of Oxford, Headington, Oxford, UK. .
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Źródło:
Communications biology [Commun Biol] 2024 Feb 24; Vol. 7 (1), pp. 229. Date of Electronic Publication: 2024 Feb 24.
MPET : a multi-network poroelastic and transport theory for predicting absorption of monoclonal antibodies delivered by subcutaneous injection.
Autorzy:
Wang H; School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA. Hu T; School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA. Leng Y; School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA. de Lucio M; School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA. Gomez H; School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA.; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
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Źródło:
Drug delivery [Drug Deliv] 2023 Dec; Vol. 30 (1), pp. 2163003.
A 1D model characterizing the role of spatiotemporal contraction distributions on lymph transport.
Autorzy:
Sedaghati F; The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. Dixon JB; The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.; The Wallace H. Coulter Georgia Tech/Emory Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. Gleason RL Jr; The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. .; The Wallace H. Coulter Georgia Tech/Emory Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Room 216F, Atlanta, GA, 30313, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 01; Vol. 13 (1), pp. 21241. Date of Electronic Publication: 2023 Dec 01.
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