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Tytuł :
Lymphocyte subsets with the lowest decline at baseline and the slow lowest rise during recovery in COVID-19 critical illness patients with diabetes mellitus.
Autorzy :
Liu D; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
Lan L; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Luo D; Department of Science and Education, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Zhao B; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Wei G; Department of Surgical Second Ward, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
He Y; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China.
Zhang R; Department of Vice Headmaster's Office, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
Liu Y; Department of Internal Medicine, The Public and Health Clinic Centre of Chengdu, Chengdu, China. Electronic address: .
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Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 Sep; Vol. 167, pp. 108341. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
B-Lymphocytes*
CD4-Positive T-Lymphocytes*
CD8-Positive T-Lymphocytes*
Killer Cells, Natural*
T-Lymphocyte Subsets*
Coronavirus Infections/*blood
Diabetes Complications/*blood
Diabetes Mellitus/*metabolism
Pneumonia, Viral/*blood
Adult ; Aged ; Antigens, CD19 ; Betacoronavirus ; CD3 Complex ; CD4 Lymphocyte Count ; CD56 Antigen ; Comorbidity ; Coronavirus Infections/complications ; Critical Illness ; Disease Progression ; Female ; Humans ; Length of Stay ; Lymphocyte Count ; Lymphocyte Subsets ; Lymphocytes ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Prognosis ; Retrospective Studies ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Quantitative and time-resolved miRNA pattern of early human T cell activation.
Autorzy :
Diener C; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Hart M; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Kehl T; Center for Bioinformatics, Saarland Informatics Campus, Saarland University, 66123 Saarbrücken, Germany.
Rheinheimer S; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Ludwig N; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Krammes L; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Pawusch S; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
Lenhof K; Center for Bioinformatics, Saarland Informatics Campus, Saarland University, 66123 Saarbrücken, Germany.
Tänzer T; Institute of Virology and Center of Human and Molecular Biology, Saarland University, 66421 Homburg, Germany.
Schub D; Department of Transplant and Infection Immunology, Saarland University, 66421 Homburg, Germany.
Sester M; Department of Transplant and Infection Immunology, Saarland University, 66421 Homburg, Germany.
Walch-Rückheim B; Institute of Virology and Center of Human and Molecular Biology, Saarland University, 66421 Homburg, Germany.
Keller A; Chair for Clinical Bioinformatics, Saarland University, 66123 Saarbrücken, Germany.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lenhof HP; Center for Bioinformatics, Saarland Informatics Campus, Saarland University, 66123 Saarbrücken, Germany.
Meese E; Institute of Human Genetics, Saarland University, 66421 Homburg, Germany.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Oct 09; Vol. 48 (18), pp. 10164-10183.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphocyte Activation*
CD4-Positive T-Lymphocytes/*metabolism
MicroRNAs/*metabolism
T-Lymphocyte Subsets/*metabolism
Adult ; CD4-Positive T-Lymphocytes/cytology ; Female ; Gene Expression Regulation ; Gene Regulatory Networks ; Humans ; T-Lymphocyte Subsets/cytology ; Young Adult
Czasopismo naukowe
Tytuł :
Absolute B cell counts in blood predict long-term response in follicular lymphoma patients treated with rituximab without chemotherapy.
Autorzy :
Junlén HR; Unit of Hematology, Department of Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Medicinsk enhet Hematologi, Tema Cancer, Karolinska University Hospital, Stockholm, Sweden.
Lockmer S; Unit of Hematology, Department of Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Medicinsk enhet Hematologi, Tema Cancer, Karolinska University Hospital, Stockholm, Sweden.
Kimby E; Unit of Hematology, Department of Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Wahlin BE; Unit of Hematology, Department of Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden. .; Medicinsk enhet Hematologi, Tema Cancer, Karolinska University Hospital, Stockholm, Sweden. .
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Źródło :
Annals of hematology [Ann Hematol] 2020 Oct; Vol. 99 (10), pp. 2357-2366. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
B-Lymphocytes*
Lymphocyte Count*
Antineoplastic Agents/*therapeutic use
Immunosuppressive Agents/*therapeutic use
Lymphoma, Follicular/*drug therapy
Rituximab/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Clinical Trials, Phase II as Topic/statistics & numerical data ; Clinical Trials, Phase III as Topic/statistics & numerical data ; Datasets as Topic ; Female ; Follow-Up Studies ; Humans ; Interferon alpha-2/administration & dosage ; Kaplan-Meier Estimate ; Lymphocyte Subsets ; Lymphoma, Follicular/blood ; Male ; Middle Aged ; Monocytes ; Multicenter Studies as Topic/statistics & numerical data ; Prognosis ; Randomized Controlled Trials as Topic/statistics & numerical data ; Rituximab/administration & dosage ; Young Adult
Czasopismo naukowe
Tytuł :
Lymphocyte activation after a high-intensity street dance class.
Autorzy :
Borges L; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Gorjão R; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Gray SR; Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Martins TR; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Santos VC; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Momesso CM; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Pithon-Curi TC; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
Hatanaka E; Institute of Physical Activity and Sport Sciences (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil.
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Źródło :
PloS one [PLoS One] 2020 Sep 21; Vol. 15 (9), pp. e0239516. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*/drug effects
Dancing/*physiology
L-Selectin/*analysis
Creatine Kinase, MB Form/blood ; Dancing/education ; Heart Rate ; Humans ; Inflammation ; Lymphocyte Count ; Male ; Reactive Oxygen Species/blood ; Tetradecanoylphorbol Acetate/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł :
T-Cell Subset Counts in Peripheral Blood Can Be Used as Discriminatory Biomarkers for Diagnosis and Severity Prediction of Coronavirus Disease 2019.
Autorzy :
Jiang M; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Guo Y; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Luo Q; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Huang Z; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Zhao R; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Liu S; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Le A; Department of Transfusion, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Li J; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Wan L; Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2020 Jun 29; Vol. 222 (2), pp. 198-202.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus*
Clinical Laboratory Techniques*
Lymphocyte Count*
T-Lymphocyte Subsets*
Coronavirus Infections/*diagnosis
Coronavirus Infections/*immunology
Pneumonia, Viral/*diagnosis
Pneumonia, Viral/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; CD4 Lymphocyte Count ; CD4-CD8 Ratio ; CD8-Positive T-Lymphocytes ; Female ; Humans ; Killer Cells, Natural ; Male ; Middle Aged ; Pandemics ; Patient Acuity ; Sensitivity and Specificity ; Young Adult
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity.
Autorzy :
Kang CK; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Han GC; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Anatomy & Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kim M; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Anatomy & Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kim G; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Anatomy & Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Shin HM; Wide River Institute of Immunology, Seoul National University, Hongcheon 25159, Republic of Korea.
Song KH; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Choe PG; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Park WB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kim ES; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Kim HB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Kim NJ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kim HR; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Department of Anatomy & Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Wide River Institute of Immunology, Seoul National University, Hongcheon 25159, Republic of Korea; Medical Research Institute, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. Electronic address: .
Oh MD; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Aug; Vol. 97, pp. 313-321. Date of Electronic Publication: 2020 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Immunity, Cellular*
Lymphocyte Activation*
Coronavirus Infections/*immunology
Pneumonia, Viral/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Coronavirus Infections/physiopathology ; Cytokines/immunology ; Female ; Granzymes ; Humans ; Ki-67 Antigen ; Leukocytes, Mononuclear/immunology ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Perforin ; Pneumonia, Viral/physiopathology ; Programmed Cell Death 1 Receptor
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Cocaine Use Disorder Is Associated With Changes in Th1/Th2/Th17 Cytokines and Lymphocytes Subsets.
Autorzy :
Zaparte A; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Schuch JB; Graduate Program in Biomedical Gerontology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Viola TW; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Baptista TAS; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Beidacki AS; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
do Prado CH; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Sanvicente-Vieira B; Developmental Cognitive Neuroscience Lab, School of Health Science, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Bauer ME; Graduate Program in Biomedical Gerontology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.; Laboratory of Stress Immunology, School of Sciences, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Grassi-Oliveira R; Developmental Cognitive Neuroscience Lab, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Oct 15; Vol. 10, pp. 2435. Date of Electronic Publication: 2019 Oct 15 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Susceptibility*
Lymphocyte Count*
Cocaine-Related Disorders/*etiology
Cocaine-Related Disorders/*metabolism
Cytokines/*metabolism
Lymphocyte Subsets/*immunology
Lymphocyte Subsets/*metabolism
B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Biomarkers ; Brazil ; Cocaine-Related Disorders/diagnosis ; Female ; Humans ; Immunophenotyping ; Lymphocyte Activation/genetics ; Lymphocyte Activation/immunology ; Male ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Th17 Cells/immunology ; Th17 Cells/metabolism ; Th2 Cells/immunology ; Th2 Cells/metabolism
Czasopismo naukowe
Tytuł :
Dynamic changes in peripheral blood lymphocyte subsets in adult patients with COVID-19.
Autorzy :
Deng Z; Department of Otolaryngology - Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Zhang M; Yaxin School of Nursing, Wuhan Institute of Design and Sciences, Wuhan 430205, China.
Zhu T; Department of Otolaryngology - Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Zhili N; Department of Laboratory Science, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Liu Z; Department of Oncology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xiang R; Department of Otolaryngology - Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Zhang W; Department of Otolaryngology - Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Xu Y; Department of Otolaryngology - Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Sep; Vol. 98, pp. 353-358. Date of Electronic Publication: 2020 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*blood
Lymphocyte Subsets/*cytology
Pneumonia, Viral/*blood
Adult ; Aged ; Aged, 80 and over ; Betacoronavirus/physiology ; Comorbidity ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Electronic Health Records ; Female ; Humans ; Lymphocyte Count ; Lymphocyte Subsets/immunology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; Retrospective Studies ; Young Adult
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Immunocytometric analysis of COVID patients: A contribution to personalized therapy?
Autorzy :
Cacciapuoti S; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
De Rosa A; Dipartimento di Malattie Infettive e Emergenze Infettive, Divisione di Malattie Infettive Respiratorie, Ospedale Cotugno, AORN dei Colli, Naples, Italy.
Gelzo M; CEINGE-Biotecnologie Avanzate, Scarl, Naples, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Megna M; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Raia M; CEINGE-Biotecnologie Avanzate, Scarl, Naples, Italy.
Pinchera B; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Pontarelli A; Dipartimento di Malattie Infettive e Emergenze Infettive, Divisione di Malattie Infettive Respiratorie, Ospedale Cotugno, AORN dei Colli, Naples, Italy.
Scotto R; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Scala E; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Scarano F; Dipartimento di Malattie Infettive e Emergenze Infettive, Divisione di Malattie Infettive Respiratorie, Ospedale Cotugno, AORN dei Colli, Naples, Italy.
Scalia G; CEINGE-Biotecnologie Avanzate, Scarl, Naples, Italy.
Castaldo G; CEINGE-Biotecnologie Avanzate, Scarl, Naples, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy. Electronic address: .
Fabbrocini G; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Gentile I; Dipartimento di Medicina Clinica e Chirurgia, Università di Napoli Federico II, Naples, Italy.
Parrella R; Dipartimento di Malattie Infettive e Emergenze Infettive, Divisione di Malattie Infettive Respiratorie, Ospedale Cotugno, AORN dei Colli, Naples, Italy.
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Źródło :
Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118355. Date of Electronic Publication: 2020 Aug 29.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Coronavirus Infections/*immunology
Cytokines/*blood
Flow Cytometry/*methods
Lymphocyte Subsets/*immunology
Pneumonia, Viral/*immunology
Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antibodies, Monoclonal, Humanized/pharmacology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/virology ; Female ; Humans ; Inflammation/immunology ; Inflammation/virology ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Patient Admission ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/virology ; Precision Medicine ; Prospective Studies ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Not just antibodies: B cells and T cells mediate immunity to COVID-19.
Autorzy :
Cox RJ; Influenza Centre, Department of Clinical Science and Department of Microbiology, University of Bergen and Haukeland University Hospital, Bergen, Norway. .
Brokstad KA; Broeglemann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.
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Źródło :
Nature reviews. Immunology [Nat Rev Immunol] 2020 Oct; Vol. 20 (10), pp. 581-582.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Cellular*
B-Lymphocytes/*immunology
Betacoronavirus/*pathogenicity
Coronavirus Infections/*immunology
Cytokines/*biosynthesis
Pneumonia, Viral/*immunology
T-Lymphocyte Subsets/*immunology
Antibodies, Viral/biosynthesis ; Asymptomatic Diseases ; B-Lymphocytes/virology ; Betacoronavirus/immunology ; Coronavirus Infections/pathology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Humans ; Immunity, Humoral ; Immunization, Passive/methods ; Immunoglobulin G/biosynthesis ; Immunoglobulin M/biosynthesis ; Immunologic Memory ; Lymphocyte Activation ; Pandemics ; Pneumonia, Viral/pathology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Severity of Illness Index ; T-Lymphocyte Subsets/virology ; Time Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Prediction Model Based on the Combination of Cytokines and Lymphocyte Subsets for Prognosis of SARS-CoV-2 Infection.
Autorzy :
Luo Y; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Mao L; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Yuan X; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Xue Y; Department of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Lin Q; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Tang G; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Song H; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China.
Wang F; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China. .
Sun Z; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095, Wuhan, 430030, China. .
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Źródło :
Journal of clinical immunology [J Clin Immunol] 2020 Oct; Vol. 40 (7), pp. 960-969. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Betacoronavirus/*immunology
Coronavirus Infections/*mortality
Cytokines/*blood
Lymphocyte Subsets/*immunology
Pneumonia, Viral/*mortality
Aged ; Aged, 80 and over ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; Biomarkers/blood ; China/epidemiology ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/blood ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Cytokines/immunology ; Female ; Humans ; Length of Stay ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Prognosis ; RNA, Viral/isolation & purification ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Assessment/methods
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
The characteristics and predictive role of lymphocyte subsets in COVID-19 patients.
Autorzy :
Zhang W; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Li L; Department of Surgery, Wuhan Jinyintan Hospital, Wuhan, Hubei province, 430023, China.
Liu J; Department of Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Chen L; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Zhou F; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Jin T; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Jiang L; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Li X; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Yang M; Department of Plastic surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
Wang H; Department of Hematology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei province, 430014, China.
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Oct; Vol. 99, pp. 92-99. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*immunology
Lymphocyte Subsets/*physiology
Pneumonia, Viral/*immunology
Adult ; Female ; Humans ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Flow Cytometry Identifies Risk Factors and Dynamic Changes in Patients with COVID-19.
Autorzy :
Moratto D; Flow Cytometry Unit, Clinical Chemistry Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Chiarini M; Flow Cytometry Unit, Clinical Chemistry Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Giustini V; Flow Cytometry Unit, Clinical Chemistry Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.; Clinical Research Development and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
Serana F; Hematology Unit, Clinical Chemistry Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Magro P; Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali di Brescia, Brescia, Italy.
Roccaro AM; Clinical Research Development and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, Italy.
Imberti L; CREA Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Castelli F; Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali di Brescia, Brescia, Italy.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, room 5-3950, 10 Center Drive, Bethesda, MD, 20892, USA. .
Quiros-Roldan E; Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali di Brescia, Brescia, Italy. .
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Źródło :
Journal of clinical immunology [J Clin Immunol] 2020 Oct; Vol. 40 (7), pp. 970-973. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Letter; Research Support, N.I.H., Intramural
MeSH Terms :
Flow Cytometry*
Betacoronavirus/*immunology
Clinical Laboratory Techniques/*methods
Coronavirus Infections/*mortality
Lymphocyte Subsets/*immunology
Pneumonia, Viral/*mortality
Adult ; Aged ; Aged, 80 and over ; Betacoronavirus/pathogenicity ; Cell Separation ; Coronavirus Infections/blood ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Female ; Host Microbial Interactions/immunology ; Humans ; Kaplan-Meier Estimate ; Lymphocyte Count ; Lymphocyte Subsets/metabolism ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/immunology ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Risk Factors ; Severity of Illness Index
SCR Disease Name :
COVID-19
Raport
Tytuł :
CD32 is enriched on CD4dimCD8bright T cells.
Autorzy :
Virdi AK; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States of America.
Wallace J; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States of America.
Barbian H; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States of America.
Richards MH; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States of America.
Ritz EM; Biostatistics and Bioinformatics Core, Rush University Medical Center, Chicago, IL, United States of America.
Sha B; Infectious Diseases Division, Rush Medical College, Chicago, IL, United States of America.
Al-Harthi L; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Sep 22; Vol. 15 (9), pp. e0239157. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*blood
Receptors, IgG/*metabolism
T-Lymphocyte Subsets/*immunology
Anti-HIV Agents/therapeutic use ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Cell Separation ; Flow Cytometry ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1/isolation & purification ; Humans ; Receptors, IgG/immunology ; T-Lymphocyte Subsets/metabolism ; Viral Load
Czasopismo naukowe
Tytuł :
Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19.
Autorzy :
Qun S; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Wang Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Chen J; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Huang X; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Guo H; Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Lu Z; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Wang J; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zheng C; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Ma Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zhu Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xia D; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Wang Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
He H; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Wang Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Fei M; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Yin Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zheng M; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xu Y; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Ge W; Department of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Hu F; School of Public Health, Bengbu Medical College, Bengbu, China.
Zhou J; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Sep 02; Vol. 11, pp. 2160. Date of Electronic Publication: 2020 Sep 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Severity of Illness Index*
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Neutrophils/*immunology
Pneumonia, Viral/*immunology
T-Lymphocyte Subsets/*immunology
Adult ; Aged ; Biomarkers ; Cardiovascular Diseases ; Coronavirus Infections/virology ; Female ; Humans ; Interleukin-10/blood ; Interleukin-6/blood ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/virology ; Pulse ; Risk Factors ; Sex Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications.
Autorzy :
Loganathan S; Clinical Sciences, Clinical Development and Medical Affairs, Biocon Biologics India Ltd , Bengaluru, India.
Athalye SN; Clinical Sciences, Clinical Development and Medical Affairs, Biocon Biologics India Ltd , Bengaluru, India.
Joshi SR; Consultant, Joshi Clinic and Lilavati Hospital , Mumbai, India.
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Źródło :
Expert opinion on biological therapy [Expert Opin Biol Ther] 2020 Sep; Vol. 20 (9), pp. 1025-1031. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus*
Antibodies, Monoclonal, Humanized/*therapeutic use
Antigens, CD/*immunology
Antigens, Differentiation, T-Lymphocyte/*immunology
Coronavirus Infections/*drug therapy
Coronavirus Infections/*immunology
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*immunology
Antibodies, Monoclonal, Humanized/pharmacology ; Cell Differentiation/drug effects ; Cell Differentiation/physiology ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cytokines/antagonists & inhibitors ; Cytokines/immunology ; Humans ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/physiology ; Pandemics ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia.
Autorzy :
Wang F; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Nie J; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wang H; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhao Q; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiong Y; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Deng L; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Song S; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ma Z; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Mo P; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhang Y; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2020 May 11; Vol. 221 (11), pp. 1762-1769.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Subsets*/immunology
Coronavirus Infections/*complications
Coronavirus Infections/*physiopathology
Pneumonia/*etiology
Pneumonia/*physiopathology
Pneumonia, Viral/*complications
Pneumonia, Viral/*physiopathology
Adult ; Aged ; Betacoronavirus/isolation & purification ; China ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Female ; Flow Cytometry ; Humans ; Lymphocyte Count ; Male ; Middle Aged ; Pandemics ; Pneumonia/diagnosis ; Pneumonia/therapy ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Prognosis ; Treatment Outcome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Concepts in immuno-oncology: tackling B cell malignancies with CD19-directed bispecific T cell engager therapies.
Autorzy :
Viardot A; Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
Locatelli F; Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Sapienza, University of Rome, Rome, Italy.
Stieglmaier J; Early Development Hematology/Oncology, Amgen Research (Munich) GmbH, Staffelseestraße 2, 81477, Munich, Germany. .
Zaman F; Amgen Inc., Thousand Oaks, CA, USA.
Jabbour E; Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
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Źródło :
Annals of hematology [Ann Hematol] 2020 Oct; Vol. 99 (10), pp. 2215-2229. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antibodies, Bispecific/*therapeutic use
Antigens, CD19/*immunology
Antigens, Neoplasm/*immunology
Antineoplastic Agents, Immunological/*therapeutic use
B-Lymphocyte Subsets/*immunology
Lymphoma, B-Cell/*therapy
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*therapy
Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Adult ; Antibodies, Bispecific/administration & dosage ; Antibodies, Bispecific/adverse effects ; Antibodies, Bispecific/economics ; Antineoplastic Agents, Immunological/administration & dosage ; Antineoplastic Agents, Immunological/adverse effects ; Antineoplastic Agents, Immunological/economics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Child ; Clinical Trials as Topic ; Combined Modality Therapy ; Cost-Benefit Analysis ; Cytokine Release Syndrome/etiology ; Cytokine Release Syndrome/prevention & control ; Drug Costs ; Humans ; Immunotherapy, Adoptive/adverse effects ; Immunotherapy, Adoptive/economics ; Infusions, Intravenous ; Injections, Subcutaneous ; Lymphoma, B-Cell/drug therapy ; Lymphoma, B-Cell/immunology ; Neoplasm, Residual ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/immunology ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Premedication ; Quality of Life ; T-Lymphocyte Subsets/immunology ; Treatment Outcome ; Tumor Burden ; Tumor Escape
Czasopismo naukowe
Tytuł :
Impact of radiotherapy on circulating lymphocyte subsets in patients with esophageal cancer.
Autorzy :
Lv Y; Shandong Provincial Qianfoshan Hospital, Shandong University.
Song M; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China.
Tian X; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China.
Yv X; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China.
Liang N; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China.
Zhang J; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Sep 04; Vol. 99 (36), pp. e20993.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Carcinoma, Squamous Cell/*radiotherapy
Esophageal Neoplasms/*radiotherapy
Lymphocyte Subsets/*immunology
Aged ; B-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Carcinoma, Squamous Cell/pathology ; Esophageal Neoplasms/pathology ; Female ; Humans ; Lymphocyte Count ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł :
B cell depletion with ublituximab reshapes the T cell profile in multiple sclerosis patients.
Autorzy :
Lovett-Racke AE; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: .
Gormley M; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Liu Y; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Yang Y; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Graham C; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Wray S; Hope Neurology Multiple Sclerosis Center, Knoxville, TN, USA.
Racke MK; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Shubin R; SC3 Research Group, Inc, Pasadena, CA, USA.
Twyman C; Associates in Neurology, Lexington, KY, USA.
Alvarez E; Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.
Bass A; Neurology Center of San Antonio, San Antonio, TX, USA.
Eubanks JL; TG Therapeutics, Inc., New York, NY, USA.
Fox E; Central Texas Neurology Consultants, UT Dell Medical School, Austin, TX, USA.
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2019 Jul 15; Vol. 332, pp. 187-197. Date of Electronic Publication: 2019 May 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Depletion*
Antibodies, Monoclonal/*therapeutic use
Multiple Sclerosis, Relapsing-Remitting/*drug therapy
T-Lymphocyte Subsets/*immunology
Adolescent ; Adult ; Antibodies, Monoclonal/pharmacology ; Antigens, CD20/immunology ; Female ; Humans ; Immunologic Memory ; Killer Cells, Natural/immunology ; Lymphocyte Activation ; Lymphocyte Count ; Male ; Middle Aged ; Multiple Sclerosis, Relapsing-Remitting/immunology ; Myeloid Cells/immunology ; T-Lymphocytes, Regulatory/immunology ; Young Adult
Czasopismo naukowe

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