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Wyszukujesz frazę ""Lymphocyte Activation"" wg kryterium: Temat


Tytuł :
Biphasic response of T cell activation to substrate stiffness.
Autorzy :
Yuan DJ; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Shi L; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Kam LC; Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 Jun; Vol. 273, pp. 120797. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Lymphocyte Activation*
T-Lymphocytes*
Animals ; CD28 Antigens ; Cell Communication ; Cell Proliferation ; Mice
Czasopismo naukowe
Tytuł :
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection.
Autorzy :
Le Bert N; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Clapham HE; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Tan AT; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Chia WN; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Tham CYL; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Lim JM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Kunasegaran K; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Tan LWL; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Dutertre CA; Inserm U1015, Gustave Roussy, Villejuif, France.
Shankar N; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Lim JME; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Sun LJ; Infectious Diseases, Alexandra Hospital, National University Health System, Singapore.
Zahari M; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Tun ZM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Kumar V; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Lim BL; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Lim SH; Department of Microbiology, Singapore General Hospital, Singapore.
Chia A; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Tan YJ; Infectious Diseases Translational Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore.
Tambyah PA; Infectious Disease, Department of Medicine, National University Hospital, Singapore.
Kalimuddin S; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Department of Infectious Diseases, Singapore General Hospital, Singapore.
Lye D; Infectious Diseases Translational Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; National Center of Infectious Diseases, Singapore.; Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Singapore.
Low JGH; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Department of Infectious Diseases, Singapore General Hospital, Singapore.
Wang LF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Wan WY; Department of Microbiology, Singapore General Hospital, Singapore.
Hsu LY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Bertoletti A; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Singapore Immunology Network, A*STAR, Singapore.
Tam CC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; London School of Hygiene & Tropical Medicine, London, UK.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2021 May 03; Vol. 218 (5).
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Asymptomatic Infections*
Lymphocyte Activation*
COVID-19/*immunology
Cytokines/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
Adult ; COVID-19/blood ; Cytokines/blood ; Humans ; Male ; Middle Aged ; SARS-CoV-2/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Effect of IL-15 addition on asbestos-induced suppression of human cytotoxic T lymphocyte induction.
Autorzy :
Kumagai-Takei N; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Nishimura Y; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan. .
Matsuzaki H; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.; Department of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 727-0023, Shobara, Japan.
Lee S; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Yoshitome K; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Ito T; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Otsuki T; Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
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Źródło :
Environmental health and preventive medicine [Environ Health Prev Med] 2021 Apr 19; Vol. 26 (1), pp. 50. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Asbestos/*adverse effects
CD8-Positive T-Lymphocytes/*immunology
Interleukin-15/*pharmacology
Lymphocyte Activation/*drug effects
T-Lymphocytes, Cytotoxic/*immunology
CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/metabolism ; Humans ; Lymphocyte Activation/immunology ; T-Lymphocytes, Cytotoxic/cytology ; T-Lymphocytes, Cytotoxic/drug effects ; T-Lymphocytes, Cytotoxic/metabolism
Czasopismo naukowe
Tytuł :
Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation.
Autorzy :
Chioh FW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Fong SW; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
Young BE; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.
Wu KX; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Siau A; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Krishnan S; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, ANA Futura, Campus Flemingsberg, Stockholm, Sweden.
Chan YH; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Carissimo G; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Teo LL; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Gao F; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Tan RS; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Zhong L; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Koh AS; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Tan SY; Department of Infectious Diseases, Changi General Hospital, Singapore, Singapore.
Tambyah PA; Department of Medicine, National University Hospital, Singapore, Singapore.
Renia L; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Ng LF; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Lye DC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Cheung C; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.
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Źródło :
ELife [Elife] 2021 Mar 23; Vol. 10. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
COVID-19/*complications
Cardiovascular Diseases/*etiology
Endothelium, Vascular/*pathology
Adult ; Aged ; COVID-19/immunology ; COVID-19/pathology ; Cardiovascular Diseases/immunology ; Cardiovascular Diseases/pathology ; Cytokines/immunology ; Endothelial Cells/immunology ; Endothelial Cells/pathology ; Endothelium, Vascular/immunology ; Female ; Humans ; Male ; Middle Aged ; Risk Factors
Czasopismo naukowe
Tytuł :
T Cell Activation, Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19.
Autorzy :
Zenarruzabeitia O; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Astarloa-Pando G; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Terrén I; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Orrantia A; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Pérez-Garay R; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Seijas-Betolaza I; Intensive Care Medicine Service, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, Barakaldo, Spain.
Nieto-Arana J; Infectious Disease Service, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, Barakaldo, Spain.
Imaz-Ayo N; Scientific Coordination Facility, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Pérez-Fernández S; Scientific Coordination Facility, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Arana-Arri E; Scientific Coordination Facility, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Borrego F; Immunopathology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Mar 11; Vol. 12, pp. 655934. Date of Electronic Publication: 2021 Mar 11 (Print Publication: 2021).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytotoxicity, Immunologic*
Lymphocyte Activation*
COVID-19/*immunology
Killer Cells, Natural/*immunology
Monocytes/*immunology
Receptors, Immunologic/*blood
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
Aged ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/virology ; Case-Control Studies ; Cross-Sectional Studies ; Female ; Flow Cytometry ; Host-Pathogen Interactions ; Humans ; Immunophenotyping ; Killer Cells, Natural/metabolism ; Killer Cells, Natural/virology ; Male ; Middle Aged ; Monocytes/metabolism ; Monocytes/virology ; Phenotype ; Severity of Illness Index ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology
Czasopismo naukowe
Tytuł :
Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity.
Autorzy :
Shahine A; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
Wegrecki M; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Le Nours J; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lymphocyte Activation*
Antigens/*immunology
Antigens, CD1/*immunology
Histocompatibility Antigens Class I/*immunology
Lipids/*immunology
T-Lymphocytes/*immunology
Humans
Czasopismo naukowe
Tytuł :
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19.
Autorzy :
Vella LA; Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. .; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Giles JR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Parker Institute for Cancer Immunotherapy at University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Baxter AE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Oldridge DA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Diorio C; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Kuri-Cervantes L; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Alanio C; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Parker Institute for Cancer Immunotherapy at University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Pampena MB; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Wu JE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Parker Institute for Cancer Immunotherapy at University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Chen Z; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Huang YJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Anderson EM; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Gouma S; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
McNerney KO; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Chase J; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Burudpakdee C; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Lee JH; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Apostolidis SA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Rheumatology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Huang AC; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Mathew D; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Kuthuru O; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Goodwin EC; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Weirick ME; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Bolton MJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Arevalo CP; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Ramos A; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Jasen CJ; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,19104, USA.
Conrey PE; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,19104, USA.
Sayed S; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,19104, USA.
Giannini HM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
D'Andrea K; Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Meyer NJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Behrens EM; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Bassiri H; Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Hensley SE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Henrickson SE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,19104, USA.
Teachey DT; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Betts MR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
Wherry EJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. .; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Parker Institute for Cancer Immunotherapy at University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
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Corporate Authors :
UPenn COVID Processing Unit
Źródło :
Science immunology [Sci Immunol] 2021 Mar 02; Vol. 6 (57).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
COVID-19/*immunology
Systemic Inflammatory Response Syndrome/*immunology
T-Lymphocytes/*immunology
Adolescent ; Adult ; Aging/immunology ; Child ; Child, Preschool ; Female ; Flow Cytometry ; Humans ; Leukopenia/immunology ; Male ; Young Adult
SCR Disease Name :
pediatric multisystem inflammatory disease, COVID-19 related
Czasopismo naukowe
Tytuł :
γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis.
Autorzy :
Junqueira C; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. .; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. .; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil. .
Polidoro RB; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Castro G; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.; Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Absalon S; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA.
Liang Z; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Sen Santara S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Crespo Â; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Pereira DB; Centro de Pesquisa em Medicina Tropical de Rondônia, Porto Velho, RO, Brazil.
Gazzinelli RT; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.; Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.; Plataforma de Medicina Translacional, Fundação Oswaldo Cruz, Ribeirão Preto, SP, Brazil.
Dvorin JD; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.
Lieberman J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. .; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Mar; Vol. 22 (3), pp. 347-357. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytotoxicity, Immunologic*
Lymphocyte Activation*
Phagocytosis*
Antigens, Protozoan/*immunology
Erythrocytes/*immunology
Intraepithelial Lymphocytes/*immunology
Malaria, Falciparum/*immunology
Plasmodium falciparum/*microbiology
Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Antigens, Protozoan/blood ; Boston ; Brazil ; Butyrophilins/metabolism ; Cells, Cultured ; Erythrocytes/metabolism ; Erythrocytes/parasitology ; Female ; Granzymes/metabolism ; Host-Parasite Interactions ; Humans ; Immunological Synapses/metabolism ; Immunological Synapses/parasitology ; Intraepithelial Lymphocytes/metabolism ; Intraepithelial Lymphocytes/parasitology ; Malaria, Falciparum/blood ; Malaria, Falciparum/parasitology ; Male ; Plasmodium falciparum/growth & development
Czasopismo naukowe
Tytuł :
Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 Patients.
Autorzy :
Deschler S; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Kager J; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Erber J; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Fricke L; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Koyumdzhieva P; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Georgieva A; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Lahmer T; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Wiessner JR; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Voit F; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Schneider J; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Horstmann J; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Iakoubov R; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Treiber M; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Winter C; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, 81675 Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, 81675 Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Busch DH; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany.
Knolle PA; Institute of Molecular Immunology and Experimental Oncology, University Hospital Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Protzer U; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), 38124 Braunschweig, Partner Site Munich, Germany.
Spinner CD; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.; German Center for Infection Research (DZIF), 38124 Braunschweig, Partner Site Munich, Germany.
Schmid RM; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
Quante M; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.; Freiburg University Medical Center, Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Böttcher K; Department of Internal Medicine II, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich (TUM), 81675 Munich, Germany.
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Źródło :
Viruses [Viruses] 2021 Feb 03; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
COVID-19/*immunology
Mucosal-Associated Invariant T Cells/*immunology
Adaptive Immunity ; COVID-19/physiopathology ; Cytokines/metabolism ; Female ; Granzymes/metabolism ; HLA-DR Antigens ; Humans ; Interleukin-17/metabolism ; Killer Cells, Natural/immunology ; Male ; Mucosal-Associated Invariant T Cells/metabolism ; Severity of Illness Index ; T-Lymphocyte Subsets/immunology ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Catalytic antibodies in the bone marrow and other organs of Th mice during spontaneous development of experimental autoimmune encephalomyelitis associated with cell differentiation.
Autorzy :
Aulova KS; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Urusov AE; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Toporkova LB; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Sedykh SE; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Shevchenko YA; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Tereshchenko VP; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Sennikov SV; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Budde T; Institut Für Physiologie I, Westfälische Wilhelms-Universität, Robert-Koch-Str. 27a, 48149, Munster, Germany.
Meuth SG; Department of Neurology, Westfälische Wilhelms-Universität, Albert-Schweitzer-Campus 1, 48149, Munster, Germany.
Orlovskaya IA; Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Nevinsky GA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. .
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Źródło :
Molecular biology reports [Mol Biol Rep] 2021 Feb; Vol. 48 (2), pp. 1055-1068. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Catalytic/*immunology
Cell Differentiation/*genetics
Encephalomyelitis, Autoimmune, Experimental/*immunology
Lymphocyte Activation/*immunology
Lymphocytes/*immunology
Animals ; Antibodies, Catalytic/genetics ; Bone Marrow Cells/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cell Proliferation/genetics ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Hematopoietic Stem Cells/immunology ; Hematopoietic Stem Cells/metabolism ; Humans ; Lymphocyte Activation/genetics ; Lymphocyte Count ; Mice ; Myelin-Oligodendrocyte Glycoprotein/genetics ; Myelin-Oligodendrocyte Glycoprotein/immunology ; Spleen/immunology
Czasopismo naukowe
Tytuł :
Using agonists for iNKT cells in cancer therapy.
Autorzy :
Painter GF; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand. Electronic address: .
Burn OK; Malaghan Institute of Medical Research, Wellington, New Zealand.
Hermans IF; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand; Malaghan Institute of Medical Research, Wellington, New Zealand. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Feb; Vol. 130, pp. 1-6. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Galactosylceramides/*therapeutic use
Immunotherapy/*methods
Lymphocyte Activation/*drug effects
Natural Killer T-Cells/*drug effects
Neoplasms/*therapy
Adjuvants, Immunologic/therapeutic use ; Animals ; Antigen-Presenting Cells/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cancer Vaccines/therapeutic use ; Galactosylceramides/pharmacology ; Humans ; Lymphocyte Activation/physiology ; Natural Killer T-Cells/physiology ; Natural Killer T-Cells/transplantation ; Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Programmed cell death 1-expressing CD56-negative natural killer (NK) cell expansion is a hallmark of chronic NK cell activation during dasatinib treatment.
Autorzy :
Ishiyama KI; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.
Kitawaki T; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Otsuka Y; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takaori-Kondo A; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kadowaki N; Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Feb; Vol. 112 (2), pp. 523-536. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Dasatinib/*therapeutic use
Killer Cells, Natural/*immunology
Leukemia/*drug therapy
Leukemia/*immunology
Lymphocyte Activation/*drug effects
B7-H1 Antigen/immunology ; CD56 Antigen/immunology ; Cytomegalovirus Infections/complications ; Humans ; Killer Cells, Natural/drug effects ; Lymphocyte Activation/immunology ; Lymphocyte Subsets/drug effects ; Lymphocyte Subsets/immunology ; Virus Activation/immunology
Czasopismo naukowe
Tytuł :
CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs.
Autorzy :
Johnson DK; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
Magoffin W; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
Myers SJ; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
Finnell JG; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, United States.
Hancock JC; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
Orton TS; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
Persaud SP; Division of Laboratory and Genomic Medicine, Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, United States.
Christensen KA; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, United States.
Weber KS; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jan 19; Vol. 11, pp. 561889. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
Models, Immunological*
CD4 Antigens/*metabolism
Receptors, Antigen, T-Cell, alpha-beta/*immunology
Receptors, Chimeric Antigen/*immunology
Signal Transduction/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; Antigens, Neoplasm/immunology ; Histocompatibility Antigens Class II/immunology ; Hybridomas ; Immunotherapy, Adoptive/methods ; Interleukin-2/metabolism ; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Chimeric Antigen/genetics ; Transduction, Genetic ; Yeasts/immunology
Czasopismo naukowe
Tytuł :
Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection.
Autorzy :
Files JK; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Boppana S; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Perez MD; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Sarkar S; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Lowman KE; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Qin K; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Sterrett S; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Carlin E; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Bansal A; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Sabbaj S; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Long DM; Department of Biostatistics, School of Public Health, and.
Kutsch O; Division of Infectious Diseases, Department of Medicine, School of Medicine.; Department of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kobie J; Division of Infectious Diseases, Department of Medicine, School of Medicine.
Goepfert PA; Division of Infectious Diseases, Department of Medicine, School of Medicine.; Department of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Erdmann N; Division of Infectious Diseases, Department of Medicine, School of Medicine.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Jan 04; Vol. 131 (1).
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Lymphocyte Activation*
Antigens, Differentiation/*immunology
B-Lymphocytes/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
T-Lymphocytes/*immunology
Adult ; Aged ; Aged, 80 and over ; B-Lymphocytes/pathology ; COVID-19/pathology ; Female ; Humans ; Male ; Middle Aged ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
IgA natural antibodies are produced following T-cell independent B-cell activation following stroke.
Autorzy :
Zbesko JC; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Frye JB; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Becktel DA; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Gerardo DK; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Stokes J; Department of Pediatrics, University of Arizona, Tucson, AZ 85719, USA.
Calderon K; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Nguyen TV; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA; Department of Neurology, University of Arizona, Tucson, AZ 85719, USA.
Bhattacharya D; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.
Doyle KP; Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA; Department of Neurology, University of Arizona, Tucson, AZ 85719, USA; Arizona Center on Aging, University of Arizona, Tucson, AZ 85719, USA. Electronic address: .
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Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2021 Jan; Vol. 91, pp. 578-586. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Lymphocyte Activation*
Stroke*
Animals ; B-Lymphocytes ; CD4-Positive T-Lymphocytes ; Humans ; Immunoglobulin A ; Mice
Czasopismo naukowe
Tytuł :
LCK senses asparagine for T cell activation.
Autorzy :
Raynor JL; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Chi H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 Jan; Vol. 23 (1), pp. 7-8.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Asparagine*
Lymphocyte Activation*
CD8-Positive T-Lymphocytes ; Signal Transduction ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Micropatterned soft hydrogels to study the interplay of receptors and forces in T cell activation.
Autorzy :
Zhang J; INM - Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany; Chemistry Department, Saarland University, 66123 Saarbrücken, Germany.
Zhao R; Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421 Germany.
Li B; INM - Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany.
Farrukh A; INM - Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany.
Hoth M; Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421 Germany.
Qu B; INM - Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany; Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, 66421 Germany.
Del Campo A; INM - Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany; Chemistry Department, Saarland University, 66123 Saarbrücken, Germany. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2021 Jan 01; Vol. 119, pp. 234-246. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hydrogels*
Lymphocyte Activation*
Mechanical Phenomena ; Phosphorylation ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Nuclear Receptor Subfamily 4 Group A Member 1 Overexpression Prolongs Free Flap Allotransplant Graft Survival by Inducing T-Cell Anergy in the Rat.
Autorzy :
Xiao B; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China. Electronic address: .
Zhang Y; Department of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China.
Liu S; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China.
Ding J; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China.
Yu Z; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China.
Wang T; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China.
Song B; Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi Province, China. Electronic address: .
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Źródło :
Transplantation proceedings [Transplant Proc] 2021 Jan-Feb; Vol. 53 (1), pp. 474-480. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Clonal Anergy/*immunology
Graft Survival/*immunology
Lymphocyte Activation/*immunology
Nuclear Receptor Subfamily 4, Group A, Member 1/*metabolism
T-Lymphocytes/*immunology
Animals ; Benzopyrans/pharmacology ; Free Tissue Flaps/immunology ; Free Tissue Flaps/transplantation ; Graft Rejection/immunology ; Lymphocyte Activation/drug effects ; Rats ; Rats, Inbred BN ; Rats, Inbred Lew ; Transplantation, Homologous ; Vascularized Composite Allotransplantation
Czasopismo naukowe
Tytuł :
Induction of Antigen-Independent Proliferation of Regulatory T-Cells by TNF Superfamily Ligands OX40L and GITRL.
Autorzy :
Kumar P; Department of Microbiology and Immunology, University of Illinois-College of Medicine, Chicago, IL, USA.
Arbieva ZH; Core Genomics Facility, University of Illinois at Chicago, Chicago, IL, USA.
Maienschein-Cline M; Core for Research Informatics, University of Illinois at Chicago, Chicago, IL, USA.
Ganesh BB; Flow Cytometry Core, University of Illinois at Chicago, Chicago, IL, USA.
Ramasamy S; Flow Cytometry Core, University of Illinois at Chicago, Chicago, IL, USA.
Prabhakar BS; Department of Microbiology and Immunology, University of Illinois-College of Medicine, Chicago, IL, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2248, pp. 63-71.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens/*immunology
Lymphocyte Activation/*immunology
OX40 Ligand/*metabolism
T-Lymphocytes, Regulatory/*immunology
T-Lymphocytes, Regulatory/*metabolism
Tumor Necrosis Factors/*metabolism
Animals ; Biomarkers ; Computational Biology/methods ; Gene Expression Profiling ; Immunophenotyping ; Ligands ; Lymphocyte Activation/genetics ; Mice ; Mice, Transgenic ; Multigene Family ; Tumor Necrosis Factors/genetics
Czasopismo naukowe
Tytuł :
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function.
Autorzy :
Subbannayya Y; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Haug M; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Pinto SM; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Mohanty V; Center for Systems Biology and Molecular Medicine, Yenepoya (Deemed to be University), Mangalore 575018, India.
Meås HZ; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Flo TH; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Prasad TSK; Center for Systems Biology and Molecular Medicine, Yenepoya (Deemed to be University), Mangalore 575018, India.
Kandasamy RK; Centre of Molecular Inflammation Research (CEMIR),Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 29; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*/genetics
Cell Differentiation*/immunology
Lymphocyte Activation*/genetics
Lymphocyte Activation*/immunology
Proteome*
Proteomics*/methods
CD4-Positive T-Lymphocytes/*immunology
CD4-Positive T-Lymphocytes/*metabolism
Adaptive Immunity ; Animals ; CD4-Positive T-Lymphocytes/cytology ; Cell Line ; Humans ; Immune Checkpoint Proteins/metabolism ; Mass Spectrometry ; Mice ; Signal Transduction
Czasopismo naukowe

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