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Wyszukujesz frazę ""Lymphocyte Activation"" wg kryterium: Temat


Tytuł:
The Role of the CD28 Family Receptors in T-Cell Immunomodulation.
Autorzy:
Ciesielska-Figlon K; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
Lisowska KA; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD28 Antigens*
T-Lymphocytes*
CTLA-4 Antigen ; Programmed Cell Death 1 Receptor ; Antigens, CD ; Immunity ; Immunomodulation ; Antigens, Differentiation, T-Lymphocyte ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Immunomodulatory Effects of Primed Tonsil-Derived Mesenchymal Stem Cells on Atopic Dermatitis via B Cell Regulation.
Autorzy:
Kim DK; Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.; Institute of New Frontier Research, Division of Big Data and Artificial Intelligence, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.
Lee HJ; Institute of New Frontier Research, Division of Big Data and Artificial Intelligence, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.
Lee IH; Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.
Lee JJ; Institute of New Frontier Research, Division of Big Data and Artificial Intelligence, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.; Department of Anesthesiology and Pain Medicine, College of Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon 24252, Republic of Korea.
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Źródło:
Cells [Cells] 2023 Dec 30; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dermatitis, Atopic*/therapy
Mesenchymal Stem Cells*
Animals ; NF-kappa B ; Palatine Tonsil ; Lymphocyte Activation ; CD40 Antigens
Czasopismo naukowe
Tytuł:
Studies of the Immunomodulatory Activity of Polysaccharides from the Stem of Cynomorium songaricum Based on Intestinal Microbial Analysis.
Autorzy:
Lv T; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.
Chen J; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.
He Z; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.
Chen W; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.
Zong Y; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.
Du R; College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 26; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cynomorium*
Humans ; Animals ; Mice ; Immunomodulation ; Immunosuppression Therapy ; Lymphocyte Activation ; MAP Kinase Signaling System
Czasopismo naukowe
Tytuł:
Enhancement of Immune Functions by Limosilactobacillus reuteri KBL346: In Vitro and In Vivo Studies.
Autorzy:
Park C; KoBioLabs Inc., Seoul 08826, Republic of Korea.
Ji SY; Anti-Aging Research Center, Dong-eui University, Busan 47227, Republic of Korea.; Department of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Republic of Korea.
Hwangbo H; Anti-Aging Research Center, Dong-eui University, Busan 47227, Republic of Korea.; Department of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Republic of Korea.
Shin SY; KoBioLabs Inc., Seoul 08826, Republic of Korea.
Kim MY; Anti-Aging Research Center, Dong-eui University, Busan 47227, Republic of Korea.; Department of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Republic of Korea.
Lee K; KoBioLabs Inc., Seoul 08826, Republic of Korea.
Kim DH; Anti-Aging Research Center, Dong-eui University, Busan 47227, Republic of Korea.; Department of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Republic of Korea.
Cho BR; KoBioLabs Inc., Seoul 08826, Republic of Korea.
Lee H; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
Choi YH; Anti-Aging Research Center, Dong-eui University, Busan 47227, Republic of Korea.; Department of Biochemistry, Dong-eui University College of Korean Medicine, Busan 47227, Republic of Korea.
You HJ; Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul 08826, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Limosilactobacillus reuteri*
Humans ; Infant ; Animals ; Mice ; Immunocompromised Host ; Lactobacillus ; Lymphocyte Activation ; Cyclophosphamide ; Cytokines ; Dinoprostone
Czasopismo naukowe
Tytuł:
Patients with Chronic Spinal Cord Injury Display a Progressive Alteration over the Years of the Activation Stages of the T Lymphocyte Compartment.
Autorzy:
Haro S; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Gomez-Lahoz AM; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Monserrat J; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Atienza-Pérez M; Service of Rehabilitation, National Hospital for Paraplegic Patients, Carr. de la Peraleda, S/N, 45004 Toledo, Spain.
Fraile-Martinez O; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Ortega MA; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
García-Montero C; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Díaz D; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Lopez-Dolado E; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Service of Rehabilitation, National Hospital for Paraplegic Patients, Carr. de la Peraleda, S/N, 45004 Toledo, Spain.
Álvarez-Mon M; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.; Immune System Diseases-Rheumatology Service and Internal Medicine, Prince of Asturias University Hospital (CIBEREHD), 28806 Alcala de Henares, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Spinal Cord Injuries*/metabolism
Humans ; CD4-Positive T-Lymphocytes ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Granulocyte-Macrophage-Colony-Stimulating-Factor Combined with Prostaglandin E1 Create Dendritic Cells of Leukemic Origin from AML Patients' Whole Blood and Whole Bone Marrow That Mediate Antileukemic Processes after Mixed Lymphocyte Culture.
Autorzy:
Unterfrauner M; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Rejeski HA; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Hartz A; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Bohlscheid S; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Baudrexler T; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Feng X; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Rackl E; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Li L; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
Rank A; Department of Hematology and Oncology, University Hospital of Augsburg, 86156 Augsburg, Germany.
Filippini Velázquez G; Department of Hematology and Oncology, University Hospital of Augsburg, 86156 Augsburg, Germany.
Schmid C; Department of Hematology and Oncology, University Hospital of Augsburg, 86156 Augsburg, Germany.
Schmohl J; Department of Hematology and Oncology, Diakonieklinikum Stuttgart, 70176 Stuttgart, Germany.
Bojko P; Department of Hematology and Oncology, Rotkreuzklinikum Munich, 80634 Munich, Germany.
Schmetzer H; Department of Medicine III, University Hospital of Munich, 81377 Munich, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 13; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Alprostadil*/pharmacology
Leukemia, Myeloid, Acute*
Humans ; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology ; Dendritic Cells ; Bone Marrow ; Lymphocyte Activation ; T-Lymphocytes, Regulatory ; Granulocytes ; Macrophages
Czasopismo naukowe
Tytuł:
Expression of membrane Hsp90 is a molecular signature of T cell activation.
Autorzy:
Scarneo SA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Smith AP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Favret J; Bolder BioPath INC., Boulder, CO, 80301, USA.
O'Connell R; Bolder BioPath INC., Boulder, CO, 80301, USA.
Pickeral J; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA.
Yang KW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Ferrari G; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA.
Loiselle DR; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Hughes PF; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA.
Kulkarni MM; Department of Microbiology, Ohio State University, Columbus, OH, 43210, USA.
Gargesha M; BioInVision, Inc., Mayfield, OH, 44143, USA.
Scott B; BioInVision, Inc., Mayfield, OH, 44143, USA.
Roy D; BioInVision, Inc., Mayfield, OH, 44143, USA.
Haynes BF; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
Kwiek JJ; Department of Microbiology, Ohio State University, Columbus, OH, 43210, USA.
Haystead TAJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 27; Vol. 12 (1), pp. 18091. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Lymphocyte Activation*
Arthritis, Rheumatoid*/drug therapy
Mice ; Animals ; Humans ; HSP90 Heat-Shock Proteins/metabolism ; T-Lymphocytes ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
The relationship of mRNA with protein expression in CD8+ T cells associates with gene class and gene characteristics.
Autorzy:
Nicolet BP; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
Wolkers MC; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
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Źródło:
PloS one [PLoS One] 2022 Oct 19; Vol. 17 (10), pp. e0276294. Date of Electronic Publication: 2022 Oct 19 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
AU Rich Elements*
Lymphocyte Activation*/genetics
Humans ; RNA, Messenger/metabolism ; 3' Untranslated Regions/genetics ; CD8-Positive T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
Effects of Graphene Oxide and Reduced Graphene Oxide Nanostructures on CD4 Th2 Lymphocytes.
Autorzy:
Feito MJ; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Cicuéndez M; Departamento de Química en Ciencias Farmaceúticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Casarrubios L; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Diez-Orejas R; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Fateixa S; Department of Chemistry and CICECO, University of Aveiro, 3810-193 Aveiro, Portugal.
Silva D; Centre for Mechanical Technology & Automation (TEMA), Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.; LASI-Intelligent Systems Associate Laboratory, 4804-533 Guimaräes, Portugal.
Barroca N; Centre for Mechanical Technology & Automation (TEMA), Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.; LASI-Intelligent Systems Associate Laboratory, 4804-533 Guimaräes, Portugal.
Marques PAAP; Centre for Mechanical Technology & Automation (TEMA), Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.; LASI-Intelligent Systems Associate Laboratory, 4804-533 Guimaräes, Portugal.
Portolés MT; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.; CIBER de Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, 28040 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 13; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Activation*
Nanostructures*
Antibodies ; CD4 Antigens/metabolism ; Cytokines/metabolism ; Graphite ; Peptides/metabolism ; Reactive Oxygen Species/metabolism ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes, Helper-Inducer ; Th1 Cells ; Th17 Cells ; Th2 Cells
Czasopismo naukowe
Tytuł:
Protein phosphatase 2A catalytic subunit β suppresses PMA/ionomycin-induced T-cell activation by negatively regulating PI3K/Akt signaling.
Autorzy:
Gao R; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Li X; Department of Hematopoietic Stem Cell Transplantation, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Gao H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Zhao K; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Liu X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Liu J; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Wang Q; School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Zhu Y; School of Life Sciences, Hebei University, Baoding, China.
Chen H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Xiang S; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Zhan Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Yin R; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Yu M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Ning H; Department of Hematopoietic Stem Cell Transplantation, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yang X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Li C; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
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Źródło:
The FEBS journal [FEBS J] 2022 Aug; Vol. 289 (15), pp. 4518-4535. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphocyte Activation*
Phosphatidylinositol 3-Kinases*/genetics
Protein Phosphatase 2*/genetics
Proto-Oncogene Proteins c-akt*/genetics
T-Lymphocytes*/metabolism
Animals ; Catalytic Domain ; Cytokines ; Ionomycin/pharmacology ; Mice ; Signal Transduction ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł:
Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis.
Autorzy:
Slevin SM; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Garner LC; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Lahiff C; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Tan M; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Wang LM; Department of Laboratory Medicine, Changi General Hospital, SingHealth, Singapore.
Ferry H; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Greenaway B; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Lynch K; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Geremia A; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Hughes S; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Leavens K; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Krull D; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Marks DJB; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Nevin K; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Page K; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Srinivasan N; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Tarzi R; Experimental Medicine Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK.
Klenerman P; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.; The Peter Medawar Building for Pathogen Research, University of Oxford, UK.
Travis S; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Arancibia-Cárcamo CV; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
Keshav S; NIHR Oxford Biomedical Research Centre, Translational Gastroenterology Unit, Oxford University Hospitals NHS Foundation Trust, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, UK.
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Źródło:
Journal of Crohn's & colitis [J Crohns Colitis] 2020 Oct 05; Vol. 14 (10), pp. 1446-1461.
Typ publikacji:
Journal Article
MeSH Terms:
Colitis, Ulcerative*/immunology
Colitis, Ulcerative*/pathology
Intestinal Mucosa*/immunology
Intestinal Mucosa*/pathology
Antigens, CD/*immunology
Lymphocyte Activation/*immunology
Drug Development ; Endoscopy/methods ; Humans ; Immune Checkpoint Proteins/immunology ; Inflammation/metabolism ; Patient Acuity ; Severity of Illness Index ; T-Lymphocyte Subsets ; Lymphocyte Activation Gene 3 Protein
Czasopismo naukowe
Tytuł:
Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity.
Autorzy:
Wolf B; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Piksa M; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Beley I; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Patoux A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Besson T; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Cordier V; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Voedisch B; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Schindler P; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Stöllner D; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Perrot L; Novartis Institutes for BioMedical Research, Basel, Switzerland.
von Gunten S; Institute of Pharmacology, University of Bern, Bern, Switzerland.
Brees D; Novartis Institutes for BioMedical Research, Basel, Switzerland.
Kammüller M; Novartis Institutes for BioMedical Research, Basel, Switzerland.
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Źródło:
Immunology [Immunology] 2022 Jul; Vol. 166 (3), pp. 380-407. Date of Electronic Publication: 2022 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antigen Presentation*
Lymphocyte Activation*
Glycosylation ; Polysaccharides/metabolism ; T-Lymphocytes
Czasopismo naukowe
Tytuł:
The CD8α-PILRα interaction maintains CD8 T cell quiescence.
Autorzy:
Zheng L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Han X; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Yao S; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Zhu Y; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Klement J; Yale College, Yale University, New Haven, CT, USA.
Wu S; Yale College, Yale University, New Haven, CT, USA.
Ji L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Zhu G; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Cheng X; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Tobiasova Z; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Yu W; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Huang B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Vesely MD; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Wang J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Zhang J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Quinlan E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Chen L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 May 27; Vol. 376 (6596), pp. 996-1001. Date of Electronic Publication: 2022 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
CD8 Antigens*/genetics
CD8 Antigens*/metabolism
CD8-Positive T-Lymphocytes*/immunology
Lymphocyte Activation*
Membrane Glycoproteins*/metabolism
Receptors, Immunologic*/metabolism
Animals ; Antigens ; Dendritic Cells/immunology ; Gene Deletion ; Mice
Czasopismo naukowe
Tytuł:
Universal antigen encoding of T cell activation from high-dimensional cytokine dynamics.
Autorzy:
Achar SR; Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Bourassa FXP; Department of Physics, McGill University, Montréal, Québec, Canada.
Rademaker TJ; Department of Physics, McGill University, Montréal, Québec, Canada.
Lee A; Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Kondo T; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Salazar-Cavazos E; Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Davies JS; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Taylor N; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
François P; Department of Physics, McGill University, Montréal, Québec, Canada.
Altan-Bonnet G; Immunodynamics Group, Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 May 20; Vol. 376 (6595), pp. 880-884. Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens*/immunology
CD8-Positive T-Lymphocytes*/immunology
Cytokines*
Lymphocyte Activation*
Models, Immunological*
Humans ; Immunotherapy ; Machine Learning ; Receptors, Antigen, T-Cell/metabolism
Czasopismo naukowe
Tytuł:
An updated view into the cell cycle kinetics of human T lymphocytes and the impact of irradiation.
Autorzy:
Duthoo E; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Vral A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Baeyens A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium. .; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 10; Vol. 12 (1), pp. 7687. Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes*
Cell Cycle ; Humans ; Kinetics ; Lymphocytes/metabolism ; Phytohemagglutinins/metabolism ; Phytohemagglutinins/pharmacology
Czasopismo naukowe
Tytuł:
A MLR-Based Approach to Analyze Regulators of T Lymphocyte Activation In Vivo.
Autorzy:
Koutník J; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Klepsch V; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Pommermayr M; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Thuille N; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Baier G; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Siegmund K; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 10; Vol. 23 (10). Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes*
Animals ; Lymphocyte Culture Test, Mixed ; Mice ; Spleen
Czasopismo naukowe
Tytuł:
Distinguishing activated T regulatory cell and T conventional cells by single-cell technologies.
Autorzy:
Reinhardt J; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.
Sharma V; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD), Faculty of Medicine, Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden, Dresden, Germany.
Stavridou A; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.
Lindner A; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD), Faculty of Medicine, Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden, Dresden, Germany.
Reinhardt S; Center for Molecular and Cellular Bioengineering (CMCB), DRESDEN-concept Genome Center, Technische Universität Dresden, Dresden, Germany.
Petzold A; Center for Molecular and Cellular Bioengineering (CMCB), DRESDEN-concept Genome Center, Technische Universität Dresden, Dresden, Germany.
Lesche M; Center for Molecular and Cellular Bioengineering (CMCB), DRESDEN-concept Genome Center, Technische Universität Dresden, Dresden, Germany.
Rost F; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.; Center for Information Services and High-Performance Computing (ZIH), TU Dresden, Dresden, Germany.
Bonifacio E; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD), Faculty of Medicine, Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden, Dresden, Germany.
Eugster A; Center for Regenerative Therapies Dresden, Faculty of Medicine, TU Dresden, Dresden, Germany.
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Źródło:
Immunology [Immunology] 2022 May; Vol. 166 (1), pp. 121-137. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes, Regulatory*
Biomarkers/metabolism ; Flow Cytometry ; Forkhead Transcription Factors/metabolism ; Lymphocyte Count
Czasopismo naukowe
Tytuł:
Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.
Autorzy:
Fischer K; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Bradlerova M; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Decker T; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. .; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria. .
Supper V; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18651. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Listeria monocytogenes*/metabolism
Humans ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Antigens ; Epithelial Cells/metabolism ; Lymphocyte Activation ; Antigens, CD/metabolism
Czasopismo naukowe
Tytuł:
Probiotic-guided CAR-T cells for solid tumor targeting.
Autorzy:
Vincent RL; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Gurbatri CR; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Li F; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Vardoshvili A; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Coker C; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Im J; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Ballister ER; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Rouanne M; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.
Savage T; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
de Los Santos-Alexis K; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Redenti A; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Brockmann L; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Komaranchath M; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Arpaia N; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.
Danino T; Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.; Data Science Institute, Columbia University, New York, NY 10027, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 13; Vol. 382 (6667), pp. 211-218. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy, Adoptive*/methods
Receptors, Chimeric Antigen*/immunology
Probiotics*/therapeutic use
Escherichia coli*/genetics
Escherichia coli*/immunology
Breast Neoplasms*/therapy
Colorectal Neoplasms*/therapy
Animals ; Humans ; Mice ; Lymphocyte Activation ; T-Lymphocytes/immunology ; Xenograft Model Antitumor Assays ; Antigens, Neoplasm/immunology ; Cell Engineering
Czasopismo naukowe
Tytuł:
The CD2-CD58 axis: A novel marker predicting poor prognosis in patients with low-grade gliomas and potential therapeutic approaches.
Autorzy:
Wu M; Qinzhou First People's Hospital, Qinzhou, China.
Chen Y; Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hua G; Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Chunhui L; Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Oct; Vol. 11 (10), pp. e1022.
Typ publikacji:
Journal Article
MeSH Terms:
Glioma*/genetics
Glioma*/therapy
Adult ; Humans ; Immunity, Cellular ; Kaplan-Meier Estimate ; Lymphocyte Activation ; Prognosis ; CD2 Antigens/metabolism ; CD58 Antigens/metabolism
Czasopismo naukowe

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