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Tytuł:
The Role of the CD28 Family Receptors in T-Cell Immunomodulation.
Autorzy:
Ciesielska-Figlon K; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
Lisowska KA; Department of Physiopathology, Medical University of Gdansk, 80-211 Gdansk, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD28 Antigens*
T-Lymphocytes*
CTLA-4 Antigen ; Programmed Cell Death 1 Receptor ; Antigens, CD ; Immunity ; Immunomodulation ; Antigens, Differentiation, T-Lymphocyte ; Lymphocyte Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.
Autorzy:
Fischer K; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Bradlerova M; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria.
Decker T; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria. .; Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna, Vienna, Austria. .
Supper V; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18651. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Listeria monocytogenes*/metabolism
Humans ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Antigens ; Epithelial Cells/metabolism ; Lymphocyte Activation ; Antigens, CD/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Butyrophilins: Dynamic Regulators of Protective T Cell Immunity in Cancer.
Autorzy:
Kumari R; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Hosseini ES; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.; Cellular and Molecular Pharmacology, Rutgers School of Graduate Studies, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.
Warrington KE; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Milonas T; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.
Payne KK; Medical Immunology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA.; Cellular and Molecular Pharmacology, Rutgers School of Graduate Studies, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ 08901, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 13; Vol. 24 (10). Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
T-Lymphocytes*
Neoplasms*/therapy
Humans ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Immunity, Cellular ; Antigens ; Receptors, Antigen, T-Cell, gamma-delta ; Lymphocyte Activation ; Antigens, CD/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protein phosphatase 2A catalytic subunit β suppresses PMA/ionomycin-induced T-cell activation by negatively regulating PI3K/Akt signaling.
Autorzy:
Gao R; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Li X; Department of Hematopoietic Stem Cell Transplantation, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Gao H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Zhao K; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Liu X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Liu J; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Wang Q; School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Zhu Y; School of Life Sciences, Hebei University, Baoding, China.
Chen H; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Xiang S; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Zhan Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Yin R; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Yu M; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Ning H; Department of Hematopoietic Stem Cell Transplantation, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Yang X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
Li C; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, China.
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Źródło:
The FEBS journal [FEBS J] 2022 Aug; Vol. 289 (15), pp. 4518-4535. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphocyte Activation*
Phosphatidylinositol 3-Kinases*/genetics
Protein Phosphatase 2*/genetics
Proto-Oncogene Proteins c-akt*/genetics
T-Lymphocytes*/metabolism
Animals ; Catalytic Domain ; Cytokines ; Ionomycin/pharmacology ; Mice ; Signal Transduction ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An updated view into the cell cycle kinetics of human T lymphocytes and the impact of irradiation.
Autorzy:
Duthoo E; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Vral A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Baeyens A; Radiobiology Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium. .; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 10; Vol. 12 (1), pp. 7687. Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes*
Cell Cycle ; Humans ; Kinetics ; Lymphocytes/metabolism ; Phytohemagglutinins/metabolism ; Phytohemagglutinins/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A MLR-Based Approach to Analyze Regulators of T Lymphocyte Activation In Vivo.
Autorzy:
Koutník J; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Klepsch V; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Pommermayr M; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Thuille N; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Baier G; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
Siegmund K; Institute of Cell Genetics, Medical University Innsbruck, 6020 Innsbruck, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 10; Vol. 23 (10). Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes*
Animals ; Lymphocyte Culture Test, Mixed ; Mice ; Spleen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
T cell activation niches-Optimizing T cell effector function in inflamed and infected tissues.
Autorzy:
Bala N; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
McGurk AI; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Zilch T; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Rup AN; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Carter EM; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Leddon SA; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Fowell DJ; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
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Źródło:
Immunological reviews [Immunol Rev] 2022 Mar; Vol. 306 (1), pp. 164-180. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Lymphocyte Activation*
T-Lymphocytes*
Antigen-Presenting Cells ; Cell Movement ; Chemokines ; Cytokines ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CRISPR activation and interference screens decode stimulation responses in primary human T cells.
Autorzy:
Schmidt R; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Steinhart Z; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Layeghi M; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.
Freimer JW; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Bueno R; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Nguyen VQ; Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Blaeschke F; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Ye CJ; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.; Parker Institute for Cancer Immunotherapy, University of California San Francisco, San Francisco, CA 94129, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94143, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94158, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Marson A; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, USA.; Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA 94720, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USA.; Parker Institute for Cancer Immunotherapy, University of California San Francisco, San Francisco, CA 94129, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94143, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Feb 04; Vol. 375 (6580), pp. eabj4008. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
CRISPR-Cas Systems*
Gene Regulatory Networks*
Lymphocyte Activation*
CRISPR-Associated Protein 9/*metabolism
Interferon-gamma/*biosynthesis
Interleukin-2/*biosynthesis
T-Lymphocytes/*immunology
CRISPR-Associated Protein 9/genetics ; Cell Line ; Cells, Cultured ; Gene Expression Regulation ; Genome, Human ; Humans ; Interferon-gamma/genetics ; Interleukin-2/genetics ; NF-kappa B/metabolism ; RNA-Seq ; Signal Transduction ; Single-Cell Analysis ; T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metabolic plasticity and regulation of T cell exhaustion.
Autorzy:
Li F; Gansu Provincial Key Laboratory of Evidence-Based Medicine and Clinical Translation & Lanzhou Center for Tuberculosis Research, Institute of Pathogen Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Liu H; Department of gynecology and obstetrics, Gansu Provincial Hospital, Lanzhou, China.
Zhang D; Gansu Provincial Key Laboratory of Evidence-Based Medicine and Clinical Translation & Lanzhou Center for Tuberculosis Research, Institute of Pathogen Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Ma Y; Gansu Provincial Key Laboratory of Evidence-Based Medicine and Clinical Translation & Lanzhou Center for Tuberculosis Research, Institute of Pathogen Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Zhu B; Gansu Provincial Key Laboratory of Evidence-Based Medicine and Clinical Translation & Lanzhou Center for Tuberculosis Research, Institute of Pathogen Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.; State Key Laboratory of Veterinary Etiological Biology, School of Veterinary Medicine, Lanzhou University, Lanzhou, China.
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Źródło:
Immunology [Immunology] 2022 Dec; Vol. 167 (4), pp. 482-494. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Oxidative Phosphorylation*
Glycolysis ; Lymphocyte Activation ; Cell Differentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Autoimmune Epithelitis and Chronic Inflammation in Sjögren's Syndrome-Related Dry Eye Disease.
Autorzy:
Ogawa Y; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
Takeuchi T; Department of Internal Medicine, Division of Rheumatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
Tsubota K; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 30; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphocyte Activation*
B-Lymphocytes/*immunology
Conjunctiva/*immunology
Lacrimal Apparatus/*immunology
Meibomian Glands/*immunology
Sjogren's Syndrome/*immunology
T-Lymphocytes/*immunology
B-Lymphocytes/pathology ; Chronic Disease ; Conjunctiva/pathology ; Humans ; Lacrimal Apparatus/pathology ; Meibomian Glands/pathology ; Mucins/immunology ; Sjogren's Syndrome/pathology ; T-Lymphocytes/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Roles for Selenoprotein I and Ethanolamine Phospholipid Synthesis in T Cell Activation.
Autorzy:
Ma C; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA.
Martinez-Rodriguez V; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA.
Hoffmann PR; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 16; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphocyte Activation*
Ethanolamine/*metabolism
Ethanolaminephosphotransferase/*physiology
Phospholipids/*metabolism
Selenoproteins/*physiology
T-Lymphocytes/*physiology
Cellular Reprogramming ; Humans ; Phosphatidylethanolamines/metabolism ; Selenium/metabolism ; Selenocysteine/metabolism ; Selenoproteins/chemistry ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of Cyclooxygenase-2 Expression in Human T Cells by Glucocorticoid Receptor-Mediated Transrepression of Nuclear Factor of Activated T Cells.
Autorzy:
Cacheiro-Llaguno C; R&D Unit Allergy & Immunology, LETI Pharma, S.L.U., Tres Cantos, 28760 Madrid, Spain.
Hernández-Subirá E; Labcorp Development S.A.U., 28050 Madrid, Spain.
Díaz-Muñoz MD; Toulouse Institute for Infectious and Inflammatory Diseases, Inserm, CNRS, University Paul Sabatier, CHU Purpan, 31300 Toulouse, France.
Fresno M; Departamento de Biología Molecular and Instituto de Biología Molecular (IUBM), Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, 28006 Madrid, Spain.; Immune System Development and Function Unit, Centro de Biología Molecular 'Severo Ochoa' (CBMSO), Consejo Superior de Investigaciones Científicas (CSIC)-UAM, 28049 Madrid, Spain.
Serrador JM; Immune System Development and Function Unit, Centro de Biología Molecular 'Severo Ochoa' (CBMSO), Consejo Superior de Investigaciones Científicas (CSIC)-UAM, 28049 Madrid, Spain.
Íñiguez MA; Departamento de Biología Molecular and Instituto de Biología Molecular (IUBM), Universidad Autónoma de Madrid (UAM), 28049 Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, 28006 Madrid, Spain.; Immune System Development and Function Unit, Centro de Biología Molecular 'Severo Ochoa' (CBMSO), Consejo Superior de Investigaciones Científicas (CSIC)-UAM, 28049 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 31; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclooxygenase 2*/genetics
Cyclooxygenase 2*/metabolism
Receptors, Glucocorticoid*/metabolism
T-Lymphocytes*/metabolism
Humans ; Dexamethasone/pharmacology ; Glucocorticoids/pharmacology ; Glucocorticoids/metabolism ; Lymphocyte Activation ; Mammals/metabolism ; Transcriptional Activation ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
T-cell activation and bacterial infection in skin wounds of recessive dystrophic epidermolysis bullosa patients.
Autorzy:
Alexeev V; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Huitema L; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Phillips T; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Cepeda R; DEBRA MEXICO, Guadalupe, Mexico.; Julio Salas Dermatology, Guadalupe, Mexico.
de Los Cobos D; DEBRA MEXICO, Guadalupe, Mexico.
Perez RIM; DEBRA MEXICO, Guadalupe, Mexico.
Salas-Garza M; DEBRA MEXICO, Guadalupe, Mexico.
Fajardo-Ramirez OR; School of Medicine and Health Sciences, Thechnological University of Monterrey, Monterrey, Mexico.
Ringpfeil F; Ringpfeil Advanced Dermatology, Haverford, Pennsylvania, USA.
Uitto J; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Salas-Alanis JC; DEBRA MEXICO, Guadalupe, Mexico.; Julio Salas Dermatology, Guadalupe, Mexico.
Igoucheva O; Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
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Źródło:
Experimental dermatology [Exp Dermatol] 2022 Sep; Vol. 31 (9), pp. 1431-1442. Date of Electronic Publication: 2022 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Infections*
Epidermolysis Bullosa Dystrophica*/pathology
T-Lymphocytes*/immunology
Antigens ; Collagen Type VII ; Humans ; Keratinocytes/pathology ; Lymphocyte Activation ; Programmed Cell Death 1 Receptor ; Staphylococcus aureus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Compromised levels of CD6 and reduced T cell activation in the aged immune system.
Autorzy:
Kureel AK; Department of Biotechnology, Motilal Nehru National Institute of Technology (MNNIT) Allahabad, Prayagraj, India.
Saini S; Department of Biotechnology, Motilal Nehru National Institute of Technology (MNNIT) Allahabad, Prayagraj, India.
Singh B; Department of Biotechnology, Motilal Nehru National Institute of Technology (MNNIT) Allahabad, Prayagraj, India.
Singh K; Stem Cell Facility, Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow, India.
Rai AK; Department of Biotechnology, Motilal Nehru National Institute of Technology (MNNIT) Allahabad, Prayagraj, India.
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Źródło:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2021 Jul; Vol. 26 (5), pp. 483-490. Date of Electronic Publication: 2021 May 10.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Immunosenescence*
Lymphocyte Activation*
Aging/*metabolism
Antigens, CD/*metabolism
Antigens, Differentiation, T-Lymphocyte/*metabolism
Leukocytes, Mononuclear/*metabolism
T-Lymphocytes/*metabolism
Age Factors ; Aged ; Aged, 80 and over ; Aging/genetics ; Aging/immunology ; Antigens, CD/genetics ; Antigens, Differentiation, T-Lymphocyte/genetics ; Cells, Cultured ; Female ; Humans ; Leukocytes, Mononuclear/immunology ; Male ; Middle Aged ; T-Lymphocytes/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effect of Antigen Dose and Antigen Presenting Process on T Cell Stimulation: A Method for Enrichment of TB10.4 Antigen-specific T-cell Clones.
Autorzy:
Motiee M; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. .
Zavaran Hosseini A; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. .
Soudi S; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. .
Hassanzadeh SM; Vaccine Production Unit, Research and Production Complex, Pasteur Institute of Iran, Karaj, Iran. m_.
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Źródło:
Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2021 Jun 06; Vol. 20 (3), pp. 364-375. Date of Electronic Publication: 2021 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Activation*
Antigens, Bacterial/*immunology
BCG Vaccine/*immunology
T-Lymphocytes/*immunology
Administration, Inhalation ; Animals ; Antigens, Bacterial/administration & dosage ; BCG Vaccine/administration & dosage ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Female ; Immunotherapy, Adoptive ; Interferon-gamma/metabolism ; Mice, Inbred BALB C ; T-Lymphocytes/metabolism ; T-Lymphocytes/transplantation ; Time Factors ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10.
Autorzy:
Campanello L; Department of Physics, University of Maryland College Park, College Park, Maryland, United States of America.; Institute for Physical Science and Technology, University of Maryland College Park, College Park, Maryland, United States of America.
Traver MK; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Shroff H; Department of Physics, University of Maryland College Park, College Park, Maryland, United States of America.; Laboratory of High-Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, United States of America.
Schaefer BC; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Losert W; Department of Physics, University of Maryland College Park, College Park, Maryland, United States of America.; Institute for Physical Science and Technology, University of Maryland College Park, College Park, Maryland, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 May 20; Vol. 17 (5), pp. e1007986. Date of Electronic Publication: 2021 May 20 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Lymphocyte Activation*
B-Cell CLL-Lymphoma 10 Protein/*metabolism
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Algorithms ; Animals ; Autophagosomes/immunology ; Autophagosomes/metabolism ; B-Cell CLL-Lymphoma 10 Protein/chemistry ; B-Cell CLL-Lymphoma 10 Protein/genetics ; Cell Line ; Computational Biology ; Computer Simulation ; Mice ; Models, Biological ; Monte Carlo Method ; Polymerization ; Proteolysis ; Receptors, Antigen, T-Cell/metabolism ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-γ protection to influenza virus in mouse.
Autorzy:
Wu W; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA. .
Tian L; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA.
Zhang W; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA.
Booth JL; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA.
Ainsua-Enrich E; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.
Kovats S; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA.; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Brown BR; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA.
Metcalf JP; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, RP1, 800 N. Research Pkwy., Oklahoma City, OK, 73104, USA. .; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. .; Veterans Affairs Medical Center, Oklahoma City, OK, USA. .
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Źródło:
Respiratory research [Respir Res] 2021 Apr 20; Vol. 22 (1), pp. 112. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Activation*
Influenza A Virus, H1N1 Subtype/*immunology
Interferon-gamma/*metabolism
Lung/*immunology
Orthomyxoviridae Infections/*immunology
Smoke/*adverse effects
T-Lymphocytes/*immunology
Tobacco Products/*toxicity
Animals ; Disease Models, Animal ; Female ; Host-Pathogen Interactions ; Influenza A Virus, H1N1 Subtype/pathogenicity ; Lung/metabolism ; Lung/virology ; Male ; Mice, Inbred C57BL ; Orthomyxoviridae Infections/metabolism ; Orthomyxoviridae Infections/virology ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology ; Time Factors ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity.
Autorzy:
Shahine A; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
Wegrecki M; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Le Nours J; Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphocyte Activation*
Antigens/*immunology
Antigens, CD1/*immunology
Histocompatibility Antigens Class I/*immunology
Lipids/*immunology
T-Lymphocytes/*immunology
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Blinatumomab-induced T cell activation at single cell transcriptome resolution.
Autorzy:
Huo Y; Shanghai Institute of Hematology, State Key Laboratory for Medical Genomics, National Research Center for Translational Medicine, Collaborative Innovation Center of Hematology, RuiJin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Building 11, No. 197, Ruijin No.2 Rd, Shanghai, 200025, P.R. China.; Amgen Asia R&D Center, Amgen Biopharmaceutical R&D (Shanghai) Co., Ltd., 13F, Building 2, No. 4560, Jinke Rd, Shanghai, 201210, P.R. China.
Sheng Z; Shanghai Institute of Hematology, State Key Laboratory for Medical Genomics, National Research Center for Translational Medicine, Collaborative Innovation Center of Hematology, RuiJin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Building 11, No. 197, Ruijin No.2 Rd, Shanghai, 200025, P.R. China.; Amgen Asia R&D Center, Amgen Biopharmaceutical R&D (Shanghai) Co., Ltd., 13F, Building 2, No. 4560, Jinke Rd, Shanghai, 201210, P.R. China.
Lu DR; Genome Analysis Unit, Amgen Research, Amgen Inc.,, South San Francisco, California, USA.
Ellwanger DC; Genome Analysis Unit, Amgen Research, Amgen Inc.,, South San Francisco, California, USA.
Li CM; Genome Analysis Unit, Amgen Research, Amgen Inc.,, South San Francisco, California, USA.
Homann O; Genome Analysis Unit, Amgen Research, Amgen Inc.,, South San Francisco, California, USA.
Wang S; Genome Analysis Unit, Amgen Research, Amgen Inc.,, South San Francisco, California, USA.
Yin H; Amgen Asia R&D Center, Amgen Biopharmaceutical R&D (Shanghai) Co., Ltd., 13F, Building 2, No. 4560, Jinke Rd, Shanghai, 201210, P.R. China. .
Ren R; Shanghai Institute of Hematology, State Key Laboratory for Medical Genomics, National Research Center for Translational Medicine, Collaborative Innovation Center of Hematology, RuiJin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Building 11, No. 197, Ruijin No.2 Rd, Shanghai, 200025, P.R. China. .
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Źródło:
BMC genomics [BMC Genomics] 2021 Mar 01; Vol. 22 (1), pp. 145. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bispecific*/pharmacology
Antineoplastic Agents*/pharmacology
Lymphocyte Activation*
T-Lymphocytes/*drug effects
Humans ; OX40 Ligand ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation.
Autorzy:
Roberts A; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.
Bentley L; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Tang T; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Stewart F; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Pallini C; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Juvvanapudi J; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Wallace GR; Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, B15 2TT, UK.
Cooper AJ; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.
Scott A; Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, B15 2TT, UK.
Thickett D; Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, B15 2TT, UK.
Lugg ST; Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Birmingham, B15 2TT, UK.
Bancroft H; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Hemming B; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Ferris C; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Langman G; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Robinson A; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Chapman J; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Naidu B; MIDRU, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.
Pinkney T; Academic Department of Surgery, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, Birmingham, B15 2GW, UK.
Taylor GS; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.
Brock K; Diagnostics, Drugs, Devices and Biomarkers, Cancer Research UK Clinical Trials Unit, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Stamataki Z; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.
Brady CA; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Curnow SJ; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Gordon J; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Qureshi O; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.; Celentyx Ltd, Birmingham Research Park, Vincent Drive, Edgbaston, Birmingham, B15 2SQ, UK.
Barnes NM; Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK. .
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 17; Vol. 11 (1), pp. 4030. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal, Humanized/*pharmacology
Lymphocyte Activation/*drug effects
T-Lymphocytes/*metabolism
Antibodies, Monoclonal, Humanized/metabolism ; B7-H1 Antigen/drug effects ; B7-H1 Antigen/immunology ; B7-H1 Antigen/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cytokines/immunology ; Hepatitis A Virus Cellular Receptor 2/immunology ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immunotherapy/methods ; Lymphocyte Activation/genetics ; Neoplasms/immunology ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/drug effects ; Programmed Cell Death 1 Receptor/metabolism ; T-Lymphocytes/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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