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Wyszukujesz frazę ""Lymphocytes"" wg kryterium: Temat


Tytuł:
Unveiling the immune system aging in single-cell resolution.
Autorzy:
Chan CL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China.; School of Biological Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pok Fu Lam Road, Hong Kong, SAR, China.
Sugimura R; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China.; Centre for Translational Stem Cell Biology, Rm1105, 11/F, 17W, Hong Kong Science and Technology Park, Shatin, N.T., Hong Kong SAR, China.
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Źródło:
Journal of leukocyte biology [J Leukoc Biol] 2024 Jan 05; Vol. 115 (1), pp. 16-18.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
T-Lymphocytes, Helper-Inducer*
Germinal Center*
Animals ; Mice ; B-Lymphocytes ; Lymph Nodes ; T-Lymphocytes, Regulatory ; Aging
Czasopismo naukowe
Tytuł:
Universal recording of immune cell interactions in vivo.
Autorzy:
Nakandakari-Higa S; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
Walker S; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Department of Quantitative and Computational Biology, Princeton University, Princeton, NJ, USA.
Canesso MCC; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
van der Heide V; Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Chudnovskiy A; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
Kim DY; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Jacobsen JT; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Institute for Immunology and Transfusion Medicine, Rikshospitalet, University of Oslo, Oslo, Norway.
Parsa R; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Bilanovic J; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
Parigi SM; Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA.
Fiedorczuk K; Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY, USA.
Fuchs E; Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Bilate AM; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
Pasqual G; Laboratory of Synthetic Immunology, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.
Mucida D; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Kamphorst AO; Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Pritykin Y; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. .; Department of Computer Science, Princeton University, Princeton, NJ, USA. .
Victora GD; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA. .
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Źródło:
Nature [Nature] 2024 Mar; Vol. 627 (8003), pp. 399-406. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
CD40 Ligand*
Animals ; Mice ; CD40 Antigens ; Cell Communication ; T-Lymphocytes, Helper-Inducer/metabolism ; CD4-Positive T-Lymphocytes ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
An angel or a devil? Current view on the role of CD8 T cells in the pathogenesis of myasthenia gravis.
Autorzy:
Peng Y; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China. .; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China. .
Yang H; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen Q; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Jin H; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Xue YH; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Du MQ; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Liu S; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Yao SY; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 20; Vol. 22 (1), pp. 183. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD8-Positive T-Lymphocytes*
Myasthenia Gravis, Autoimmune, Experimental*/metabolism
Animals ; Humans ; T-Lymphocytes, Helper-Inducer/metabolism ; T-Lymphocytes, Regulatory ; Autoantigens/metabolism
Czasopismo naukowe
Tytuł:
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission.
Autorzy:
Baker KF; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. .; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. .
McDonald D; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Hulme G; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Hussain R; Genomics Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Coxhead J; Genomics Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Swan D; School of Medicine, University of Sunderland, Sunderland, UK.
Schulz AR; Deutsches Rheuma-Forschungszentrum Berlin, A Leibniz Institute, Berlin, Germany.
Mei HE; Deutsches Rheuma-Forschungszentrum Berlin, A Leibniz Institute, Berlin, Germany.
MacDonald L; School of Infection and Immunity, Glasgow University, Glasgow, UK.
Pratt AG; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Filby A; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Anderson AE; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Isaacs JD; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
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Źródło:
Nature communications [Nat Commun] 2024 Feb 05; Vol. 15 (1), pp. 1063. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/metabolism
Arthritis, Rheumatoid*
Humans ; CD4-Positive T-Lymphocytes ; T-Lymphocyte Subsets ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Tytuł:
Naturally occurring T cell mutations enhance engineered T cell therapies.
Autorzy:
Garcia J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Moonlight Bio, Seattle, WA, USA.
Daniels J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Moonlight Bio, Seattle, WA, USA.
Lee Y; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Zhu I; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Cheng K; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Liu Q; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Goodman D; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Burnett C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Law C; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Thienpont C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Alavi J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Azimi C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Montgomery G; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Roybal KT; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA. .; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, USA. .; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. .; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA. .; Gladstone-UCSF Institute for Genomic Immunology, San Francisco, CA, USA. .; UCSF Cell Design Institute, San Francisco, CA, USA. .
Choi J; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA. .; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7999), pp. 626-634. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Evolution, Molecular*
Immunotherapy, Adoptive*/methods
Lymphoma, T-Cell, Cutaneous*/genetics
Lymphoma, T-Cell, Cutaneous*/immunology
Lymphoma, T-Cell, Cutaneous*/pathology
Lymphoma, T-Cell, Cutaneous*/therapy
Mutation*
T-Lymphocytes*/immunology
T-Lymphocytes*/metabolism
T-Lymphocytes*/transplantation
Humans ; CARD Signaling Adaptor Proteins/genetics ; CARD Signaling Adaptor Proteins/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cytokines/biosynthesis ; Cytokines/immunology ; Cytokines/metabolism ; Guanylate Cyclase/genetics ; Guanylate Cyclase/metabolism ; Phosphatidylinositol 3-Kinases ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
Autoreactive T cells target peripheral nerves in Guillain-Barré syndrome.
Autorzy:
Súkeníková L; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Mallone A; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Schreiner B; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Ripellino P; Department of Neurology, Neurocenter of Southern Switzerland EOC, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.
Nilsson J; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Stoffel M; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.; Medical Faculty, University of Zurich, Zurich, Switzerland.
Ulbrich SE; Animal Physiology, Institute of Agricultural Sciences, ETH Zurich, Zurich, Switzerland.
Sallusto F; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.; Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
Latorre D; Institute of Microbiology, ETH Zurich, Zurich, Switzerland. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7997), pp. 160-168. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*
CD8-Positive T-Lymphocytes*/immunology
CD8-Positive T-Lymphocytes*/pathology
Guillain-Barre Syndrome*/blood
Guillain-Barre Syndrome*/cerebrospinal fluid
Guillain-Barre Syndrome*/etiology
Guillain-Barre Syndrome*/immunology
Peripheral Nerves*/immunology
Peripheral Nerves*/pathology
Peripheral Nervous System Diseases*/complications
Peripheral Nervous System Diseases*/immunology
Peripheral Nervous System Diseases*/pathology
Th1 Cells*/immunology
Th1 Cells*/pathology
Humans ; Biopsy ; HLA-DR Antigens/immunology ; Immunodominant Epitopes/immunology ; Myelin Sheath/immunology ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/pathology ; Immunologic Memory
Czasopismo naukowe
Tytuł:
Single-cell metabolite profiling enables information-rich classification of lymphocyte types and subtypes.
Autorzy:
Pan S; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
Liu C; State Key Laboratory of Complex, Severe, and Rare Diseases, Peking Union Medical College Hospital, Beijing 100730, P. R. China. .
Yao H; Division of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing 100029, P. R. China.
Pan X; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
Li J; Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
Yang J; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
Du M; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
Liu P; State Key Laboratory of Complex, Severe, and Rare Diseases, Peking Union Medical College Hospital, Beijing 100730, P. R. China. .
Zhang S; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
Zhang X; Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China. .
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Źródło:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Jan 04; Vol. 60 (4), pp. 392-395. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocytes*
CD8-Positive T-Lymphocytes*/metabolism
Humans ; CD4-Positive T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł:
Egg-sensitised infants have elevated CD4 effector memory T regulatory cells from birth.
Autorzy:
Gamez C; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Leffler J; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Clark S; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Corscadden K; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Prescott SL; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.; Perth Children's Hospital, Nedlands, Western Australia, Australia.; The Nova Institute for Health, Baltimore, Maryland, USA.; Family and Community Medicine, University of Maryland, Baltimore, Maryland, USA.
Palmer DJ; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Strickland D; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2024 Jan; Vol. 54 (1), pp. 34-45. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Leukocytes, Mononuclear*
T-Lymphocytes*
Infant, Newborn ; Infant ; Humans ; Allergens ; CD4-Positive T-Lymphocytes ; Immunoglobulin E ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Tytuł:
Hedgehog signalling in CD4 T helper cell polarisation.
Autorzy:
Hanna J; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK.
de la Roche M; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK. Electronic address: .
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Źródło:
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Mar; Vol. 168, pp. 106518. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Review; Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/cytology
CD4-Positive T-Lymphocytes*/metabolism
Hedgehog Proteins*/metabolism
Signal Transduction*
Cell Differentiation ; T-Lymphocytes, Helper-Inducer ; Transcription Factors/metabolism ; Humans ; Animals
Czasopismo naukowe
Tytuł:
Diffuse large B-cell lymphoma: the significance of CD8 tumor-infiltrating lymphocytes exhaustion mediated by TIM3/Galectin-9 pathway.
Autorzy:
Zhu Q; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, 637000, China.; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China.
Yang Y; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China.
Chen K; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China.
Zhang Q; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China.
Huang Y; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, 637000, China.; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China.
Jian S; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, 637000, China. .; Department of Pathology, North Sichuan Medical College, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan Nan Road, Nanchong, 637000, Sichuan, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 18; Vol. 22 (1), pp. 174. Date of Electronic Publication: 2024 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Lymphoma, Large B-Cell, Diffuse*/pathology
Humans ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Lymphocytes, Tumor-Infiltrating ; Ligands ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Flow cytometry quantification of tumor-infiltrating lymphocytes to predict the survival of patients with diffuse large B-cell lymphoma.
Autorzy:
Yu T; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Xu-Monette ZY; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.; Duke University Cancer Institute, Durham, NC, United States.
Lagoo A; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Shuai W; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Wang B; Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Neff J; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Carrillo LF; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Carlsen ED; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.; Duke University Cancer Institute, Durham, NC, United States.
Pina-Oviedo S; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.
Young KH; Hematopathology Division and Department of Pathology, Duke University Medical Center, Durham, NC, United States.; Duke University Cancer Institute, Durham, NC, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Jan 29; Vol. 15, pp. 1335689. Date of Electronic Publication: 2024 Jan 29 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocytes, Tumor-Infiltrating*
Lymphoma, Large B-Cell, Diffuse*/pathology
Humans ; Flow Cytometry ; T-Lymphocytes/pathology ; Monocytes ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Single-cell analysis of T lymphocytes infiltrating colorectal carcinoma: the dilemma of specificity.
Autorzy:
Lizarralde-Guerrero M; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France.; Université Paris-Saclay, Faculté de Médecine, Kremlin-Bicêtre, France.
Zucaro L; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France.; Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Kroemer G; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France.; Institut du Cancer Paris CARPEM, Department of Biology, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
Pol JG; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France.
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Źródło:
Oncoimmunology [Oncoimmunology] 2024 Jan 04; Vol. 13 (1), pp. 2300520. Date of Electronic Publication: 2024 Jan 04 (Print Publication: 2024).
Typ publikacji:
Editorial
MeSH Terms:
T-Lymphocytes*
Colorectal Neoplasms*/genetics
Humans ; Single-Cell Analysis ; Lymphocytes, Tumor-Infiltrating ; Microsatellite Instability
Opinia redakcyjna
Tytuł:
Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function.
Autorzy:
Braverman EL; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
McQuaid MA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Schuler H; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Qin M; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; School of Medicine, Tsinghua University, Beijing, China.
Hani S; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Hippen K; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Monlish DA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dobbs AK; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ramsey MJ; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Kemp F; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Wittmann C; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ramgopal A; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Brown H; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Blazar B; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Byersdorfer CA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105488. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Signal Transduction*
Gene Expression*/genetics
T-Lymphocytes*/cytology
T-Lymphocytes*/enzymology
T-Lymphocytes*/immunology
Humans ; Cytokines/metabolism ; Mitochondria/metabolism ; Th2 Cells/metabolism ; Memory T Cells/enzymology ; Glucose/metabolism ; CD4-Positive T-Lymphocytes/enzymology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
TCR β chain repertoire characteristic between healthy human CD4+ and CD8+ T cells.
Autorzy:
Li G; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Chen Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Liu Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Gao Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Jia R; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Lv Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Li Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Wang Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Han G; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
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Źródło:
Bioscience reports [Biosci Rep] 2024 Mar 29; Vol. 44 (3).
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Antigen, T-Cell, alpha-beta*/genetics
CD8-Positive T-Lymphocytes*
Humans ; Receptors, Antigen, T-Cell/genetics ; HLA Antigens ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
Autorzy:
Jing ZL; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China.; Department of Pathology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.
Liu GL; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China.
Zhou N; Department of Pathology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, 510120, China.
Xu DY; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China.
Feng N; Department of Pathology, Dongguan Songshan Lake Tungwah Hospital, Dongguan, 523413, China.
Lei Y; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China.
Ma LL; Department of Pathology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Tang MS; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China.
Tong GH; Department of Pathology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510415, China.
Tang N; Department of Pathology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, China. .
Deng YJ; Department of Pathology, School of Basic Medical Sciences and Nan Fang Hospital, Southern Medical University, Guangzhou, 510515, China. .; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 13; Vol. 14 (1), pp. 6053. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Cytotoxic*
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Humans ; Animals ; Mice ; Interferon-gamma/pharmacology ; CD8-Positive T-Lymphocytes ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
CD4 T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy.
Autorzy:
Franken A; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Bila M; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, 3000 Leuven, Belgium; Department of General Medical Oncology, UZ Leuven, 3000 Leuven, Belgium; Department of Oral and Maxillofacial Surgery, UZ Leuven, Leuven 3000, Belgium.
Mechels A; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Kint S; Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium.
Van Dessel J; Department of Oral and Maxillofacial Surgery, UZ Leuven, Leuven 3000, Belgium.
Pomella V; Digestive Oncology, KU Leuven, UZ Leuven, Leuven 3000, Belgium.
Vanuytven S; Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium.
Philips G; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Bricard O; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Xiong J; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Boeckx B; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Hatse S; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, 3000 Leuven, Belgium; Department of General Medical Oncology, UZ Leuven, 3000 Leuven, Belgium.
Van Brussel T; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Schepers R; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium.
Van Aerde C; Department of Imaging and Pathology, KU Leuven, UZ Leuven, Leuven 3000, Belgium.
Geurs S; Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium; Department of Biomolecular Medicine, UZ Ghent, Ghent 9052, Belgium.
Vandecaveye V; Otorhinolaryngology, Head and Neck Surgery, Leuven 3000, Belgium.
Hauben E; Otorhinolaryngology, Head and Neck Surgery, Leuven 3000, Belgium.
Vander Poorten V; Otorhinolaryngology, Head and Neck Surgery, Leuven 3000, Belgium; Department of Oncology, Section Head and Neck Oncology, Leuven 3000, Belgium.
Verbandt S; Digestive Oncology, KU Leuven, UZ Leuven, Leuven 3000, Belgium.
Vandereyken K; Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium.
Qian J; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Tejpar S; Digestive Oncology, KU Leuven, UZ Leuven, Leuven 3000, Belgium.
Voet T; Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium.
Clement PM; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, 3000 Leuven, Belgium; Department of General Medical Oncology, UZ Leuven, 3000 Leuven, Belgium. Electronic address: .
Lambrechts D; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; VIB Center for Cancer Biology, Leuven 3000, Belgium; KU Leuven Institute for Single Cell Omics (LISCO), Leuven 3000, Belgium. Electronic address: .
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Źródło:
Immunity [Immunity] 2024 Mar 12; Vol. 57 (3), pp. 541-558.e7. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Head and Neck Neoplasms*/drug therapy
Humans ; Squamous Cell Carcinoma of Head and Neck ; B7-H1 Antigen/genetics ; CTLA-4 Antigen ; CD4-Positive T-Lymphocytes ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells.
Autorzy:
Ding R; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Yu X; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Hu Z; Department of Immunology, Key Laboratory of Immune Microenvironment and Disease, the School of Basic Medicine, Nanjing Medical University, Nanjing 211166, China.
Dong Y; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Huang H; Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Zhang Y; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Han Q; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ni ZY; Clinical Medical College, Hebei University of Engineering, Handan 056038, Hebei, China; Central Laboratory, Hebei Collaborative Innovation Center of Tumor Microecological Metabolism Regulation, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China; Affiliated Hospital of Hebei Engineering University, Handan 056002, Hebei, China. Electronic address: .
Zhao R; Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: .
Ye Y; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: .
Zou Q; Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: .
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Źródło:
Immunity [Immunity] 2024 Mar 12; Vol. 57 (3), pp. 528-540.e6. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
Neoplasms*/genetics
Neoplasms*/metabolism
Humans ; CTLA-4 Antigen ; Lactic Acid/metabolism ; Forkhead Transcription Factors/genetics ; Lymphocytes, Tumor-Infiltrating ; Tumor Microenvironment ; Ubiquitin-Specific Proteases/metabolism
Czasopismo naukowe
Tytuł:
Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development.
Autorzy:
Kim T; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Martínez-Bonet M; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Laboratory of Immune-regulation, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Wang Q; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Hackert N; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Rheumatology, Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Institute for Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Sparks JA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Baglaenko Y; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Koh B; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Darbousset R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Laza-Briviesca R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Chen X; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Medical Center, Cincinnati, OH, USA.
Aguiar VRC; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Chiu DJ; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Westra HJ; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands.
Gutierrez-Arcelus M; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Weirauch MT; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Medical Center, Cincinnati, OH, USA.; Divisions of Human Genetics, Biomedical Informatics, and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Raychaudhuri S; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Rao DA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Nigrovic PA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. .; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Mar 09; Vol. 15 (1), pp. 2150. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*/metabolism
Arthritis, Rheumatoid*
Humans ; Inducible T-Cell Co-Stimulator Protein/metabolism ; CD28 Antigens/metabolism ; Alleles ; T-Lymphocytes, Helper-Inducer ; Chromosomal Proteins, Non-Histone/metabolism
Czasopismo naukowe
Tytuł:
Tregs from human blood differentiate into nonlymphoid tissue-resident effector cells upon TNFR2 costimulation.
Autorzy:
Mensink M; Department of Immunology and Oncode Institute.
Verleng LJ; Department of Immunology and Oncode Institute.
Schrama E; Department of Immunology and Oncode Institute.
Janssen GM; Center for Proteomics and Metabolomics.
Tjokrodirijo RT; Center for Proteomics and Metabolomics.
van Veelen PA; Center for Proteomics and Metabolomics.
Jiang Q; Department of Immunology, and.
Pascutti MF; Department of Immunology, and.
van der Hoorn ML; Department of Obstetrics and Gynaecology, Leiden University Medical Center, Leiden, Netherlands.
Eikmans M; Department of Immunology, and.
de Kivit S; Department of Immunology and Oncode Institute.
Borst J; Department of Immunology and Oncode Institute.
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Źródło:
JCI insight [JCI Insight] 2024 Mar 08; Vol. 9 (5). Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Tumor Necrosis Factor, Type II*
T-Lymphocytes, Regulatory*
Humans ; CD28 Antigens ; Lymphocytes ; Thymus Gland
Czasopismo naukowe
Tytuł:
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 T cells.
Autorzy:
Park JE; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Kim TS; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Zeng Y; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Mikolaj M; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Il Ahn J; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Alam MS; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Monnie CM; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15260, USA.
Shi V; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Zhou M; Protein Characterization Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Chun TW; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Maldarelli F; HIV Dynamics and Replication Program, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.
Narayan K; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Ahn J; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15260, USA.
Ashwell JD; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Strebel K; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Lee KS; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Mar 05; Vol. 15 (1), pp. 2017. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
HIV-1*
Humans ; Centrosome ; Carcinogenesis ; Cell Transformation, Neoplastic ; Aneuploidy ; CD4-Positive T-Lymphocytes
Czasopismo naukowe

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