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Tytuł :
Analysis of Lymphotoxin Alpha Expression in Human Retina and Generation of Expression Vectors to Functional Characterization of Polymorphisms in the Tumor Necrosis Factor Locus.
Autorzy :
Usategui-Martín R; Instituto Universitario de Oftalmobiología Aplicada (IOBA), University of Valladolid, Valladolid, Spain. .
Rodriguez-Hernández I; Molecular Medicine Unit, Departament of Medicine, University of Salamanca, Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Instituto de Biología Molecular y Celular del Cáncer (IBMCC), University of Salamanca-CSIC, Salamanca, Spain.
González-Sarmiento R; Molecular Medicine Unit, Departament of Medicine, University of Salamanca, Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Instituto de Biología Molecular y Celular del Cáncer (IBMCC), University of Salamanca-CSIC, Salamanca, Spain.
Sobas EM; Instituto Universitario de Oftalmobiología Aplicada (IOBA), University of Valladolid, Valladolid, Spain.; Nursing School, University of Valladolid, Valladolid, Spain.
Pastor-Jimeno JC; Instituto Universitario de Oftalmobiología Aplicada (IOBA), University of Valladolid, Valladolid, Spain.; Departament of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.; Red Temática de Investigación Cooperativa en Salud (RETICS), Oftared, Instituto de Salud Carlos III, Valladolid, Spain.; Centro en Red de Medicina Regenerativa y Terapia Celular de Castilla y León, Valladolid, Spain.
Pastor-Idoate S; Instituto Universitario de Oftalmobiología Aplicada (IOBA), University of Valladolid, Valladolid, Spain. .; Departament of Ophthalmology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. .; Red Temática de Investigación Cooperativa en Salud (RETICS), Oftared, Instituto de Salud Carlos III, Valladolid, Spain. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2248, pp. 243-250.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Genetic Vectors*/genetics
Polymorphism, Genetic*
Lymphotoxin-alpha/*genetics
Retina/*metabolism
Tumor Necrosis Factors/*genetics
Gene Order ; Genetic Loci ; Humans ; Lymphotoxin-alpha/metabolism ; Multigene Family ; Tumor Necrosis Factors/metabolism
Czasopismo naukowe
Tytuł :
The association of tumor necrosis factor alpha, lymphotoxin alpha, tumor necrosis factor receptor 1 and tumor necrosis factor receptor 2 gene polymorphisms and serum levels with periodontitis and type 2 diabetes in Serbian population.
Autorzy :
Petrovic SM; Department of Oral Medicine and Periodontology, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia. Electronic address: .
Nikolic N; Department of Human Genetics, School of Dental Medicine, University of Belgrade, Dr Subotica 1, Belgrade, Serbia. Electronic address: .
Toljic B; Department of Human Genetics, School of Dental Medicine, University of Belgrade, Dr Subotica 1, Belgrade, Serbia. Electronic address: .
Arambasic-Jovanovic J; Department of Molecular Biology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia. Electronic address: .
Milicic B; Department for Medical Statistics and Informatics, School of Dental Medicine, University of Belgrade, Dr Subotica 1, Belgrade, Serbia. Electronic address: .
Milicic T; Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotica 13, Belgrade, Serbia. Electronic address: .
Jotic A; Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotica 13, Belgrade, Serbia. Electronic address: .
Vidakovic M; Department of Molecular Biology, Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia. Electronic address: .
Milasin J; Department of Human Genetics, School of Dental Medicine, University of Belgrade, Dr Subotica 1, Belgrade, Serbia. Electronic address: .
Pucar A; Department of Oral Medicine and Periodontology, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia. Electronic address: .
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Źródło :
Archives of oral biology [Arch Oral Biol] 2020 Dec; Vol. 120, pp. 104929. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/genetics
Lymphotoxin-alpha*/blood
Lymphotoxin-alpha*/genetics
Periodontitis*/genetics
Receptors, Tumor Necrosis Factor, Type I*/blood
Receptors, Tumor Necrosis Factor, Type I*/genetics
Receptors, Tumor Necrosis Factor, Type II*/blood
Receptors, Tumor Necrosis Factor, Type II*/genetics
Tumor Necrosis Factor-alpha*/blood
Tumor Necrosis Factor-alpha*/genetics
Case-Control Studies ; Humans ; Polymorphism, Single Nucleotide ; Serbia
Czasopismo naukowe
Tytuł :
Roflumilast prevents lymphotoxin α (TNF-β)-induced inflammation activation and degradation of type 2 collagen in chondrocytes.
Autorzy :
Zhao J; Department of Central Laboratory, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, 130033, China.
Duan L; Department of Central Laboratory, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, 130033, China.
Wang R; Department of Radiotherapy, Tonghua Central Hospital, Tonghua, 134001, China.
Liu Y; Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, 130033, Jilin, China. .
Jiang J; Department of Central Laboratory, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, 130033, China. .
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Źródło :
Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2020 Dec; Vol. 69 (12), pp. 1191-1199. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphotoxin-alpha*
Aminopyridines/*pharmacology
Benzamides/*pharmacology
Chondrocytes/*metabolism
Collagen Type II/*metabolism
Inflammation/*chemically induced
Inflammation/*prevention & control
Phosphodiesterase 4 Inhibitors/*pharmacology
Cell Line ; Chondrocytes/drug effects ; Cyclopropanes/pharmacology ; Cytokines/metabolism ; Extracellular Matrix/drug effects ; Humans ; Receptors, Tumor Necrosis Factor, Type II/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Type 3 Innate Lymphoid Cells Direct Goblet Cell Differentiation via the LT-LTβR Pathway during Listeria Infection.
Autorzy :
Pian Y; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Chai Q; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; .
Ren B; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; and.
Wang Y; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; and.
Lv M; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Qiu J; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.
Zhu M; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; .; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; and.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Aug 01; Vol. 205 (3), pp. 853-863. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation/*immunology
Goblet Cells/*immunology
Listeria/*immunology
Listeriosis/*immunology
Lymphocytes/*immunology
Lymphotoxin-alpha/*immunology
Signal Transduction/*immunology
Animals ; Cell Differentiation/genetics ; Goblet Cells/pathology ; Listeriosis/genetics ; Listeriosis/pathology ; Lymphocytes/pathology ; Lymphotoxin beta Receptor ; Lymphotoxin-alpha/genetics ; Mice ; Mice, Knockout ; NF-kappa B/genetics ; NF-kappa B/immunology ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB.
Autorzy :
Buhrmann C; Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.
Kunnumakkara AB; Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.
Popper B; Biomedical Center, Core facility animal models, Ludwig-Maximilian-University Munich, D-82152 Martinsried, Germany.; Institute of Pathology, School of Medicine, Technical University of Munich, D-81675 Munich, Germany.
Majeed M; Sabinsa Corporation, East Windsor, NJ 08520, USA.
Aggarwal BB; Inflammation Research Center, San Diego, CA 92126, USA.
Shakibaei M; Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 31; Vol. 21 (7). Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cinnamates/*metabolism
Colonic Neoplasms/*metabolism
Colorectal Neoplasms/*metabolism
Fluorouracil/*metabolism
Lymphotoxin-alpha/*metabolism
Monoterpenes/*metabolism
Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Biomarkers, Tumor/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival ; Cinnamates/pharmacology ; Colonic Neoplasms/pathology ; Colorectal Neoplasms/pathology ; Fluorouracil/pharmacology ; Humans ; Lymphotoxin-alpha/pharmacology ; NF-kappa B/metabolism ; Phosphorylation ; Signal Transduction/drug effects ; Transcription Factor RelA/metabolism
Czasopismo naukowe
Tytuł :
Lymphotoxin targeted to salivary and lacrimal glands induces tertiary lymphoid organs and cervical lymphadenopathy and reduces tear production.
Autorzy :
Truman LA; ENT Department, West Suffolk Hospital, Hardwick Lane, Bury St Edmunds, UK.; Yale School of Public Health, New Haven, CT, USA.
Bentley KL; Yale School of Public Health, New Haven, CT, USA.
Ruddle NH; Yale School of Public Health, New Haven, CT, USA.
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Źródło :
European journal of immunology [Eur J Immunol] 2020 Mar; Vol. 50 (3), pp. 418-425. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Lacrimal Apparatus/*pathology
Lymphadenopathy/*pathology
Lymphotoxin-alpha/*metabolism
Salivary Glands/*pathology
Tertiary Lymphoid Structures/*pathology
Animals ; Lymphadenopathy/genetics ; Lymphoma, B-Cell, Marginal Zone/genetics ; Lymphoma, B-Cell, Marginal Zone/immunology ; Lymphoma, B-Cell, Marginal Zone/pathology ; Lymphotoxin-alpha/genetics ; Mice ; Mice, Transgenic ; Sjogren's Syndrome/genetics ; Sjogren's Syndrome/immunology ; Sjogren's Syndrome/pathology ; Tears/metabolism ; Tertiary Lymphoid Structures/genetics
Czasopismo naukowe
Tytuł :
Genetic Distribution of the LTA +252 A>G and TNFA -308 G > A Polymorphisms in the Moroccan Population.
Autorzy :
Aznag FZ; Laboratory of Cellular Biology and Molecular Genetics, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco.
Moutaoufik MT; Department of Biochemistry, University of Regina, Regina, SK, Canada.
Korrida A; Laboratory of Cellular Biology and Molecular Genetics, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco.; Higher Institute of Nursing Professions and Health Techniques of Agadir, Ministry of Health, Agadir, Morocco.
Izaabel EH; Laboratory of Cellular Biology and Molecular Genetics, Faculty of Sciences, Ibn Zohr University, Agadir, Morocco.
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Źródło :
Genetic testing and molecular biomarkers [Genet Test Mol Biomarkers] 2019 Dec; Vol. 23 (12), pp. 871-876. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphotoxin-alpha/*genetics
Tumor Necrosis Factor-alpha/*genetics
Adult ; Alleles ; Case-Control Studies ; Cytokines/genetics ; Female ; Gene Frequency/genetics ; Genetic Predisposition to Disease ; Genotype ; Humans ; Linkage Disequilibrium/genetics ; Lymphotoxin-alpha/blood ; Lymphotoxin-alpha/metabolism ; Male ; Morocco/epidemiology ; Polymorphism, Single Nucleotide/genetics ; Tumor Necrosis Factor-alpha/blood ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Associations of lymphotoxin-a (LTA) rs909253 A/G gene polymorphism, plasma level and risk of ankylosing spondylitis in a Chinese Han population.
Autorzy :
Zhu A; Department of Orthopaedics, The Jintan Hospital Affiliated to Jiangsu University, Changzhou, 213200, China.
Yang Z; Department of Orthopaedics, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, 213003, China.
Zhang H; Department of Orthopaedics, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, 213003, China.
Liu R; Department of Orthopaedics, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, 213003, China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 29; Vol. 10 (1), pp. 1412. Date of Electronic Publication: 2020 Jan 29.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphotoxin-alpha/*genetics
Spondylitis, Ankylosing/*genetics
Adult ; Age Factors ; Asian Continental Ancestry Group/genetics ; Case-Control Studies ; Female ; Genotyping Techniques ; HLA-B27 Antigen/blood ; HLA-B27 Antigen/immunology ; Humans ; Lymphotoxin-alpha/blood ; Male ; Polymorphism, Single Nucleotide ; Sex Factors ; Spondylitis, Ankylosing/blood ; Spondylitis, Ankylosing/epidemiology ; Spondylitis, Ankylosing/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Lymphotoxin-Beta Receptor Signaling Is Crucial for the Vascularization of Transplanted Metanephros.
Autorzy :
Brizi V; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy.
Xinaris C; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Bergamo, Italy; University of Nicosia Medical School, Nicosia, Cyprus. Electronic address: .
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Źródło :
The American journal of pathology [Am J Pathol] 2020 Jan; Vol. 190 (1), pp. 33-36. Date of Electronic Publication: 2019 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Lymphotoxin beta Receptor*
Lymphotoxin-alpha*
Animals ; Lymphotoxin-beta ; Mice ; Mice, Inbred C57BL ; Signal Transduction
Czasopismo naukowe
Tytuł :
Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity.
Autorzy :
Li C; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Lam E; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Perez-Shibayama C; Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Ward LA; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Zhang J; Department of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Lee D; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Nguyen A; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Ahmed M; Department of Medical Biophysics, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada.
Brownlie E; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Korneev KV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences and Department of Immunology, Biological Faculty, Lomonosov Moscow State University, Moscow, Russia.
Rojas O; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Sun T; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Navarre W; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
He HH; Department of Medical Biophysics, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada.
Liao S; Department of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Martin A; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Ludewig B; Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Gommerman JL; Department of Immunology, University of Toronto, Toronto, Ontario, Canada. .
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Źródło :
Science immunology [Sci Immunol] 2019 Dec 20; Vol. 4 (42).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunoglobulin A/*immunology
Lymph Nodes/*immunology
Lymphotoxin beta Receptor/*immunology
Lymphotoxin-alpha/*immunology
Mesentery/*immunology
Stromal Cells/*immunology
Animals ; Feces/microbiology ; Female ; Immunity, Mucosal ; Lymph Nodes/cytology ; Lymphotoxin beta Receptor/genetics ; Lymphotoxin-alpha/genetics ; Male ; Mesentery/cytology ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Multiple selective sweeps of ancient polymorphisms in and around LTα located in the MHC class III region on chromosome 6.
Autorzy :
Campbell MC; Department of Biology, College of Arts and Sciences, Howard University, Washington, DC, 20059, USA. .
Ashong B; Department of Biology, College of Arts and Sciences, Howard University, Washington, DC, 20059, USA.
Teng S; Department of Biology, College of Arts and Sciences, Howard University, Washington, DC, 20059, USA.
Harvey J; Department of Biology, College of Arts and Sciences, Howard University, Washington, DC, 20059, USA.
Cross CN; Department of Anatomy, College of Medicine, Howard University, Washington, DC, 20059, USA.
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Źródło :
BMC evolutionary biology [BMC Evol Biol] 2019 Dec 02; Vol. 19 (1), pp. 218. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Major Histocompatibility Complex*
Lymphotoxin-alpha/*genetics
Africa ; Animals ; Biological Evolution ; Chromosomes, Human, Pair 6 ; Evolution, Molecular ; Gene Frequency ; Genetics, Population ; Haplotypes ; Hominidae/genetics ; Human Genome Project ; Humans ; Linkage Disequilibrium ; Lymphotoxin-alpha/immunology ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Lymphotoxin-α promotes tumor angiogenesis in HNSCC by modulating glycolysis in a PFKFB3-dependent manner.
Autorzy :
Yang JG; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Wang WM; Centre of Stomatology, Xiangya Hospital, Central South University, Changsha, China.
Xia HF; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Yu ZL; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Li HM; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Ren JG; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Chen G; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Wang BK; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Jia J; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Zhang W; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Zhao YF; Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
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Źródło :
International journal of cancer [Int J Cancer] 2019 Sep 01; Vol. 145 (5), pp. 1358-1370. Date of Electronic Publication: 2019 Mar 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Head and Neck Neoplasms/*blood supply
Lymphotoxin-alpha/*metabolism
Phosphofructokinase-2/*metabolism
Squamous Cell Carcinoma of Head and Neck/*blood supply
Animals ; B-Lymphocytes/metabolism ; Cell Cycle/physiology ; Coculture Techniques ; Female ; Glycolysis ; Head and Neck Neoplasms/metabolism ; Head and Neck Neoplasms/pathology ; Heterografts ; Human Umbilical Vein Endothelial Cells ; Humans ; Immunohistochemistry ; Lymphocytes, Tumor-Infiltrating ; Lymphotoxin-alpha/biosynthesis ; Lymphotoxin-alpha/genetics ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology ; T-Lymphocytes/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Arsenite suppresses IL-2-dependent tumoricidal activities of natural killer cells.
Autorzy :
Sumi D; Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. Electronic address: .
Tsuyama H; Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Ogawa T; Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Ogawa M; Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Himeno S; Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan; Department of Health and Regulation Sciences Division of Health Chemistry, Showa University School of Pharmacy, 1-5-8, Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Feb 01; Vol. 412, pp. 115353. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arsenites/*toxicity
Cytotoxicity, Immunologic/*drug effects
Interleukin-2/*pharmacology
Killer Cells, Natural/*drug effects
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*immunology
Sodium Compounds/*toxicity
Tumor Escape/*drug effects
Animals ; Coculture Techniques ; Granzymes/genetics ; Granzymes/metabolism ; Humans ; Interferon-gamma/genetics ; Interferon-gamma/metabolism ; Interleukin-10/metabolism ; K562 Cells ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Lymphotoxin-alpha/metabolism ; Mice ; Mice, Inbred C57BL ; Receptors, KIR2DL2/genetics ; Receptors, KIR2DL2/metabolism ; Receptors, KIR2DL3/genetics ; Receptors, KIR2DL3/metabolism
Czasopismo naukowe
Tytuł :
Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration.
Autorzy :
Guo Z; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Qiu C; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.; Department of Orthopedic Surgery, Qingdao Municipal Hospital (Group), Qingdao, 266011, Shandong, China.
Mecca C; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Zhang Y; Department of Spine Surgery, Weifang People's Hospital, Weifang, 261041, Shandong, China.
Bian J; Qingdao Eye Hospital of Shandong First Medical University, Qingdao, 266000, Shandong, China.
Wang Y; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Wu X; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Wang T; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Su W; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Li X; School of Medical Imaging, Bin Zhou Medical University, Yantai, 264003, China.
Zhang W; School of Medical Imaging, Bin Zhou Medical University, Yantai, 264003, China.
Chen B; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China. .
Xiang H; Department of Orthopedic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China. .
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Źródło :
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2021 Jan 13; Vol. 22 (1), pp. 77. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Intervertebral Disc*
Intervertebral Disc Degeneration*
Nucleus Pulposus*
Aggrecans/genetics ; Animals ; Collagen Type II ; Humans ; Lymphotoxin-alpha ; Rats
Czasopismo naukowe
Tytuł :
The Absence of Lymphotoxin-α, a Herpesvirus Entry Mediator (HVEM) Ligand, Affects Herpes Simplex Virus 1 Infection In Vivo Differently than the Absence of Other HVEM Cellular Ligands.
Autorzy :
Wang S; Center for Neurobiology and Vaccine Development, Department of Surgery, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Hirose S; Center for Neurobiology and Vaccine Development, Department of Surgery, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Ghiasi H; Center for Neurobiology and Vaccine Development, Department of Surgery, Ophthalmology Research, Cedars-Sinai Medical Center, Los Angeles, California, USA .
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Źródło :
Journal of virology [J Virol] 2019 Jul 30; Vol. 93 (16). Date of Electronic Publication: 2019 Jul 30 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Herpes Simplex/*etiology
Herpes Simplex/*metabolism
Herpesvirus 1, Human/*physiology
Lymphotoxin-alpha/*deficiency
Tumor Necrosis Factor Ligand Superfamily Member 14/*metabolism
Animals ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Disease Susceptibility ; Herpes Simplex/mortality ; Herpes Simplex/pathology ; Keratitis/virology ; Lymphotoxin-alpha/genetics ; Lymphotoxin-alpha/metabolism ; Mice ; Tumor Necrosis Factors/genetics ; Tumor Necrosis Factors/metabolism ; Viral Load ; Viral Proteins/genetics ; Virus Internalization ; Virus Latency/genetics
Czasopismo naukowe
Tytuł :
Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells.
Autorzy :
Jasenosky LD; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Nambu A; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Tsytsykova AV; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.; Program in Hematology, Boston Children's Hospital, Boston, MA 02115.
Ranjbar S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Haridas V; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.
Kruidenier L; Prometheus Biosciences, San Diego, CA 92121; and.
Tough DF; Adaptive Immunity Research Unit, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage SG1 2NY, United Kingdom.
Goldfeld AE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Nov 01; Vol. 205 (9), pp. 2479-2488. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CD4-Positive T-Lymphocytes/*metabolism
Gene Expression/*genetics
Lymphotoxin-alpha/*genetics
Tumor Necrosis Factor-alpha/*genetics
Acetylation ; Binding Sites/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Conserved Sequence/genetics ; Enhancer Elements, Genetic/genetics ; Histones/genetics ; Humans ; Leukocytes, Mononuclear/metabolism ; Promoter Regions, Genetic/genetics ; Protein Binding/genetics ; RNA Polymerase II/genetics ; RNA, Messenger/genetics ; THP-1 Cells/metabolism ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
IL22BP Mediates the Antitumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans.
Autorzy :
Kempski J; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; The Calcium Signaling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Giannou AD; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Riecken K; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Zhao L; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of General Thoracic Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350003, People's Republic of China.
Steglich B; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lücke J; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Garcia-Perez L; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Karstens KF; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wöstemeier A; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nawrocki M; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pelczar P; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Witkowski M; Institut für Mikrobiologie und Infektionsimmunologie, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Nilsson S; II. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Konczalla L; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Shiri AM; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kempska J; Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wahib R; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Brockmann L; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Huber P; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gnirck AC; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Turner JE; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Zazara DE; Laboratory for Experimental Feto-Maternal Medicine, Department of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Arck PC; Laboratory for Experimental Feto-Maternal Medicine, Department of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Stein A; II. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Simon R; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Daubmann A; Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Meiners J; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Perez D; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Strowig T; Helmholtz Center for Infection Research, Braunschweig, Germany.
Koni P; Georgia Cancer Center, Augusta University, Augusta, Georgia.
Kruglov AA; German Rheumatism Research Center, a Leibniz Institute, Berlin, Germany; Belozersky Institute of Physico-Chemical Biology and Biological Faculty, Lomonosov Moscow State University, Moscow, Russia.
Sauter G; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Izbicki JR; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Guse AH; The Calcium Signaling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rösch T; Department of Interdisciplinary Endoscopy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lohse AW; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Flavell RA; Department of Immunobiology, School of Medicine, Yale University, New Haven, Connecticut; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut.
Gagliani N; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: .
Huber S; Section of Molecular Immunology und Gastroenterology, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2020 Oct; Vol. 159 (4), pp. 1417-1430.e3. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms/*metabolism
Lymphotoxin-alpha/*metabolism
Receptors, Interleukin/*metabolism
Aged ; Animals ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; RNA, Messenger/metabolism ; Receptors, Interleukin/genetics ; Survival Rate
Czasopismo naukowe
Tytuł :
Resveratrol Suppresses Cross-Talk between Colorectal Cancer Cells and Stromal Cells in Multicellular Tumor Microenvironment: A Bridge between In Vitro and In Vivo Tumor Microenvironment Study.
Autorzy :
Buhrmann C; Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.
Shayan P; Department of Parasitology, Faculty of Veterinary Medicine, University of Tehran, Tehran 141556453, Iran.
Brockmueller A; Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.
Shakibaei M; Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Sep 18; Vol. 25 (18). Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Communication/*drug effects
Resveratrol/*pharmacology
Tumor Microenvironment/*drug effects
Cell Movement/drug effects ; Cell Survival/drug effects ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; HCT116 Cells ; Humans ; Lymphotoxin-alpha/pharmacology ; NF-kappa B/metabolism ; Neoplastic Stem Cells/cytology ; Neoplastic Stem Cells/metabolism ; Signal Transduction/drug effects ; Sirtuin 1/metabolism ; Stromal Cells/cytology ; Stromal Cells/metabolism
Czasopismo naukowe
Tytuł :
Evaluation of Tear Protein Markers in Dry Eye Disease with Different Lymphotoxin-Alpha Expression Levels.
Autorzy :
Chen H; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Chen H; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Liang L; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Zhong Y; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Liang Y; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yu Y; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Huang S; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Lu X; Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address: .
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Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2020 Sep; Vol. 217, pp. 198-211. Date of Electronic Publication: 2020 Mar 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dry Eye Syndromes/*metabolism
Lymphotoxin-alpha/*biosynthesis
Tears/*metabolism
Adult ; Biomarkers/metabolism ; Cross-Sectional Studies ; Dry Eye Syndromes/diagnosis ; Female ; Humans ; Immunoassay ; Interleukin 1 Receptor Antagonist Protein/biosynthesis ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł :
PAK4 Phosphorylates Fumarase and Blocks TGFβ-Induced Cell Growth Arrest in Lung Cancer Cells.
Autorzy :
Chen T; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Wang T; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.; Department of Pharmacology, College of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Liang W; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Zhao Q; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Yu Q; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Ma CM; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Zhuo L; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Guo D; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Zheng K; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Zhou C; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Wei S; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Huang W; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Jiang J; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Liu J; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Li S; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
He J; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China. .
Jiang Y; The Institute of Cell Metabolism and Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China. .
Zhong N; State Key Laboratory of Respiratory Diseases; National Clinical Research Center of Respiratory Diseases; Guangzhou Institute of Respiratory Health; First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
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Źródło :
Cancer research [Cancer Res] 2019 Apr 01; Vol. 79 (7), pp. 1383-1397. Date of Electronic Publication: 2019 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*pathology
Cell Proliferation/*physiology
Fumarate Hydratase/*metabolism
Lung Neoplasms/*pathology
Lymphotoxin-alpha/*physiology
p21-Activated Kinases/*metabolism
14-3-3 Proteins/metabolism ; A549 Cells ; Animals ; Carcinogenesis ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/metabolism ; F-Box Proteins/metabolism ; Heterografts ; Histones/metabolism ; Humans ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Lung Neoplasms/enzymology ; Lung Neoplasms/metabolism ; Lymphotoxin-alpha/antagonists & inhibitors ; Male ; Mice ; Mice, Nude ; Phosphorylation ; Protein Binding
Czasopismo naukowe

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