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Tytuł:
Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth.
Autorzy:
Keller M; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Rohlf K; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Glotzbach A; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Leonhardt G; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Lüke S; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Derksen K; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Demirci Ö; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Göçener D; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
AlWahsh M; Leibniz Institut Für Analytische Wissenschaften - ISAS E.V, Dortmund, Germany.; Institute of Pathology and Medical Research Center (ZMF), University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.; Department of Pharmacy, AlZaytoonah University of Jordan, Amman, Jordan.
Lambert J; Leibniz Institut Für Analytische Wissenschaften - ISAS E.V, Dortmund, Germany.
Lindskog C; Department of Immunology Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Schmidt M; Department of Obstetrics and Gynecology, University Medical Center Mainz, Mainz, Germany.
Brenner W; Department of Obstetrics and Gynecology, University Medical Center Mainz, Mainz, Germany.
Baumann M; Pharmacology Department, Lead Discovery Center, Dortmund, Germany.
Zent E; Pharmacology Department, Lead Discovery Center, Dortmund, Germany.
Zischinsky ML; Pharmacology Department, Lead Discovery Center, Dortmund, Germany.
Hellwig B; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Madjar K; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Rahnenführer J; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Overbeck N; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Reinders J; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Cadenas C; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Edlund K; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Marchan R; Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jan 20; Vol. 42 (1), pp. 25. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Humans ; Female ; Phosphatidylinositol 3-Kinases ; Cell Line, Tumor ; Choline/metabolism ; Choline/therapeutic use ; RNA, Small Interfering ; Receptor, ErbB-2/metabolism ; Drug Resistance, Neoplasm/genetics ; Phospholipases/genetics
Czasopismo naukowe
Tytuł:
Shared decision-making in routine breast cancer care in Germany-A cross-sectional study.
Autorzy:
Feiten S; Institut für Versorgungsforschung in der Onkologie, Koblenz, Germany.
Scholl I; Institut und Poliklinik für Medizinische Psychologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Dünnebacke J; Brustzentrum Marienhof, Katholisches Klinikum Koblenz-Montabaur, Koblenz, Germany.
Schmidt M; Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Universitätsmedizin Mainz, Mainz, Germany.
Franzen A; Brustzentrum Kemperhof, Gemeinschaftsklinikum Mittelrhein, Koblenz, Germany.
Ernst W; Brustzentrum St. Elisabeth, Gemeinschaftsklinikum Mittelrhein, Mayen, Germany.
Spaderna H; Abteilung Gesundheitspsychologie, Pflegewissenschaft, Universität Trier, Trier, Germany.
Weide R; Praxis für Hämatologie und Onkologie, Koblenz, Germany.
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Źródło:
Psycho-oncology [Psychooncology] 2022 Jul; Vol. 31 (7), pp. 1120-1126. Date of Electronic Publication: 2022 Feb 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/therapy
Decision Making, Shared*
Cross-Sectional Studies ; Decision Making ; Female ; Germany ; Humans ; Middle Aged ; Patient Participation ; Physician-Patient Relations
Czasopismo naukowe
Tytuł:
Metronomic Chemotherapy for Metastatic Breast Cancer.
Autorzy:
Krajnak S; Department of Gynecology and Obstetrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Battista MJ; Department of Gynecology and Obstetrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Hasenburg A; Department of Gynecology and Obstetrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Schmidt M; Department of Gynecology and Obstetrics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2022; Vol. 45 (1-2), pp. 12-17. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/drug therapy
Antineoplastic Combined Chemotherapy Protocols ; Capecitabine/therapeutic use ; Cyclophosphamide/therapeutic use ; Female ; Humans ; Quality of Life ; Receptor, ErbB-2
Czasopismo naukowe
Tytuł:
Breast Cancer Patients Are at Increased Risk of Developing Uterine Serous Cancer: Implications for Counseling - A SEER Analysis.
Autorzy:
Nahshon C; Department of Gynecological Oncology, Carmel Medical Center, Haifa, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Segev Y; Department of Gynecological Oncology, Carmel Medical Center, Haifa, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Schmidt M; Department of Gynecological Oncology, Carmel Medical Center, Haifa, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Shulman K; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.; Department of Oncology, Lin and Carmel Medical Centers, Haifa, Israel.
Lavie O; Department of Gynecological Oncology, Carmel Medical Center, Haifa, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2022; Vol. 45 (12), pp. 728-735. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/epidemiology
Uterine Neoplasms*
Female ; Humans ; Risk
Czasopismo naukowe
Tytuł:
New Opportunities in Advanced Breast Cancer.
Autorzy:
Decker T; Oncology Ravensburg, Ravensburg, Germany, .
Schmidt M; Department of Obstetrics and Gynecology, University Medical Center Mainz, Mainz, Germany.
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2022; Vol. 45 (1-2), pp. 1-3. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji:
Editorial
MeSH Terms:
Breast Neoplasms*/drug therapy
Antineoplastic Combined Chemotherapy Protocols ; Female ; Humans ; Positron-Emission Tomography
Opinia redakcyjna
Tytuł:
Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes.
Autorzy:
Heimes AS; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Härtner F; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, 55131 Mainz, Germany.
Almstedt K; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Krajnak S; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Lebrecht A; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Battista MJ; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Edlund K; Leibniz-Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), 44139 Dortmund, Germany.
Brenner W; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Hasenburg A; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
Sahin U; TRON-Translational Oncology at the University Medical Center Mainz, 55131 Mainz, Germany.
Gehrmann M; Bayer AG, 42113 Wuppertal, Germany.
Hengstler JG; Leibniz-Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo), 44139 Dortmund, Germany.
Schmidt M; Department of Obstetrics and Gynecology, University Medical Center Mainz, 55131 Mainz, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 29; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
Interferon-gamma/*genetics
Aged ; Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Disease-Free Survival ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Kaplan-Meier Estimate ; Middle Aged ; Neoplasm Staging ; Progression-Free Survival ; Receptor, ErbB-2/genetics ; Receptors, Estrogen/genetics ; Receptors, Progesterone/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue.
Autorzy:
Hartmann K; BioNTech Diagnostics GmbH, An der Goldgrube 12, 55131, Mainz, Germany. .
Schlombs K; BioNTech Diagnostics GmbH, An der Goldgrube 12, 55131, Mainz, Germany.
Laible M; BioNTech Diagnostics GmbH, An der Goldgrube 12, 55131, Mainz, Germany.
Gürtler C; BioNTech Diagnostics GmbH, An der Goldgrube 12, 55131, Mainz, Germany.
Schmidt M; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Langenbeckstraße 1, 55131, Mainz, Germany.
Sahin U; BioNTech AG, An der Goldgrube 12, 55131, Mainz, Germany.
Lehr HA; Institute of Pathology, Medizin Campus Bodensee, Röntgenstraße 2, 88048, Friedrichshafen, Germany.
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Źródło:
Diagnostic pathology [Diagn Pathol] 2018 Oct 20; Vol. 13 (1), pp. 83. Date of Electronic Publication: 2018 Oct 20.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Laser Capture Microdissection*
Real-Time Polymerase Chain Reaction*
Reverse Transcriptase Polymerase Chain Reaction*
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
Carcinoma/*genetics
Carcinoma, Intraductal, Noninfiltrating/*genetics
Gene Expression Profiling/*methods
RNA, Messenger/*genetics
Tissue Fixation/*methods
Breast Neoplasms/pathology ; Carcinoma/pathology ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Estrogen Receptor alpha/genetics ; Female ; Fixatives ; Formaldehyde ; Humans ; Ki-67 Antigen/genetics ; Predictive Value of Tests ; Prognosis ; Receptor, ErbB-2/genetics ; Receptors, Progesterone/genetics ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy.
Autorzy:
Hellwig B; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Madjar K; Department of Statistics, TU Dortmund University, Dortmund, Germany.
Edlund K; Leibniz Research Centre for Working Environment and Human Factors (IfADo) at TU Dortmund University, Dortmund, Germany.
Marchan R; Leibniz Research Centre for Working Environment and Human Factors (IfADo) at TU Dortmund University, Dortmund, Germany.
Cadenas C; Leibniz Research Centre for Working Environment and Human Factors (IfADo) at TU Dortmund University, Dortmund, Germany.
Heimes AS; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Almstedt K; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Lebrecht A; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Sicking I; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Battista MJ; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Micke P; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Schmidt M; Department of Obstetrics and Gynaecology, University Hospital, Mainz, Germany.
Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors (IfADo) at TU Dortmund University, Dortmund, Germany.
Rahnenführer J; Department of Statistics, TU Dortmund University, Dortmund, Germany.
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Źródło:
PloS one [PLoS One] 2016 Dec 07; Vol. 11 (12), pp. e0167585. Date of Electronic Publication: 2016 Dec 07 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Vesicular Transport/*genetics
Breast Neoplasms/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Neoplasm Metastasis/*genetics
Receptors, Estrogen/*genetics
Ribosomes/*genetics
Aged ; Antineoplastic Agents, Hormonal/therapeutic use ; Biomarkers, Tumor/genetics ; Breast Neoplasms/drug therapy ; Disease-Free Survival ; Female ; Humans ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Ribosomal Protein L3 ; Ribosomes/drug effects ; Tamoxifen/therapeutic use
Czasopismo naukowe
Tytuł:
Consensus: soy isoflavones as a first-line approach to the treatment of menopausal vasomotor complaints.
Autorzy:
Schmidt M; a International Society for Phytosciences , Mattsies , Germany .
Arjomand-Wölkart K; b Institut Für Pharmazeutische Wissenschaften, Karl-Franzens-Universität Graz , Graz , Austria .
Birkhäuser MH; c Gynaecological Endocrinonoly and Reproductive Medicine, Medical Faculty, University of Berne , Basel , Switzerland .
Genazzani AR; d Department of Gynaecology and Obstetrics , European Society of Gynecology, University of Pisa , Pisa , Italy .
Gruber DM; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Huber J; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Kölbl H; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Kreft S; f Chair of Pharmacognostic and Phytochemical Laboratory, Faculty of Pharmacy, University of Ljubljana , Ljubljana , Slovenia .
Leodolter S; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Linsberger D; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Metka M; e 1st Department of Gynaeology and Obstetrics, University of Vienna , Wien , Austria .
Simoncini T; g Division of Obstetrics and Gynadecology , Department of Clinical and Experimental Medicine, Università Di Pisa , Pisa , Italy , and.
Vrabic Dezman L; h Slovenian Menopause Society , Kranj , Slovenia.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2016 Jun; Vol. 32 (6), pp. 427-30. Date of Electronic Publication: 2016 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Consensus*
Glycine max*
Breast Neoplasms/*prevention & control
Hot Flashes/*prevention & control
Isoflavones/*pharmacology
Menopause/*drug effects
Female ; Humans ; Isoflavones/administration & dosage ; Middle Aged
Czasopismo naukowe
Tytuł:
Intrinsic Subtypes of Primary Breast Cancer--Gene Expression Analysis.
Autorzy:
Schmidt M; Department of Obstetrics and Gynecology, University Hospital, Mainz, Germany.
Thomssen C
Untch M
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2016; Vol. 39 (3), pp. 102-10. Date of Electronic Publication: 2016 Feb 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*classification
Breast Neoplasms/*metabolism
Gene Expression Profiling/*methods
Neoplasm Proteins/*metabolism
Breast Neoplasms/pathology ; Female ; Humans
Czasopismo naukowe
Tytuł:
Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patients.
Autorzy:
Sicking I
Rommens K
Battista MJ
Böhm D
Gebhard S
Lebrecht A
Cotarelo C
Hoffmann G
Hengstler JG
Schmidt M; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany. marcus.schmidt@unimedizin-mainz.de.
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Źródło:
BMC cancer [BMC Cancer] 2014 Dec 15; Vol. 14, pp. 952. Date of Electronic Publication: 2014 Dec 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*pathology
Cyclooxygenase 2/*genetics
Cyclooxygenase 2/*metabolism
Aged ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Female ; Gene Expression Profiling ; Humans ; Immunohistochemistry ; Middle Aged ; Oligonucleotide Array Sequence Analysis ; Prognosis ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/genetics ; Receptors, Progesterone/metabolism ; Survival Analysis
Czasopismo naukowe
Tytuł:
Prognostic influence of pre-operative C-reactive protein in node-negative breast cancer patients.
Autorzy:
Sicking I; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Edlund K; Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund University of Technology, Dortmund, Germany.
Wesbuer E; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Weyer V; Institute of Medical Biometry, Epidemiology and Informatics (IMBEI), Johannes Gutenberg University, Mainz, Germany.
Battista MJ; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Lebrecht A; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Solbach C; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Grinberg M; Department of Statistics, Dortmund University of Technology, Dortmund, Germany.
Lotz J; Institute for Clinical Chemistry, Johannes Gutenberg University, Mainz, Germany.
Hoffmann G; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Rahnenführer J; Department of Statistics, Dortmund University of Technology, Dortmund, Germany.
Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund University of Technology, Dortmund, Germany.
Schmidt M; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
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Źródło:
PloS one [PLoS One] 2014 Oct 23; Vol. 9 (10), pp. e111306. Date of Electronic Publication: 2014 Oct 23 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*blood
C-Reactive Protein/*metabolism
Lymph Nodes/*pathology
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/mortality ; Breast Neoplasms/surgery ; Cell Proliferation ; Cohort Studies ; Disease-Free Survival ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genome, Human ; Humans ; Inflammation/metabolism ; Ki-67 Antigen/metabolism ; Middle Aged ; Neoplasm Metastasis ; Prognosis ; Proportional Hazards Models ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/metabolism
Czasopismo naukowe
Tytuł:
The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients.
Autorzy:
Dubsky P; Department of Surgery and Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.
Brase JC
Jakesz R
Rudas M
Singer CF
Greil R
Dietze O
Luisser I
Klug E
Sedivy R
Bachner M
Mayr D
Schmidt M
Gehrmann MC
Petry C
Weber KE
Fisch K
Kronenwett R
Gnant M
Filipits M
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Corporate Authors:
Austrian Breast and Colorectal Cancer Study Group (ABCSG)
Źródło:
British journal of cancer [Br J Cancer] 2013 Dec 10; Vol. 109 (12), pp. 2959-64. Date of Electronic Publication: 2013 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Receptor, ErbB-2/*biosynthesis
Receptors, Estrogen/*biosynthesis
Anastrozole ; Antineoplastic Agents, Hormonal/administration & dosage ; Antineoplastic Agents, Hormonal/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Cell Differentiation/physiology ; Cell Growth Processes/physiology ; Clinical Trials, Phase III as Topic ; Female ; Gene Expression Profiling ; Humans ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Recurrence, Local/pathology ; Nitriles/administration & dosage ; Prognosis ; Proportional Hazards Models ; Randomized Controlled Trials as Topic ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Retrospective Studies ; Signal Transduction ; Tamoxifen/administration & dosage ; Tamoxifen/therapeutic use ; Treatment Outcome ; Triazoles/administration & dosage
Czasopismo naukowe
Tytuł:
The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions.
Autorzy:
Müller BM; Institute of Pathology, Charité University Hospital, Campus Mitte, Berlin, Germany.
Keil E
Lehmann A
Winzer KJ
Richter-Ehrenstein C
Prinzler J
Bangemann N
Reles A
Stadie S
Schoenegg W
Eucker J
Schmidt M
Lippek F
Jöhrens K
Pahl S
Sinn BV
Budczies J
Dietel M
Denkert C
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Źródło:
PloS one [PLoS One] 2013 Jun 27; Vol. 8 (6), pp. e68252. Date of Electronic Publication: 2013 Jun 27 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Clinical Decision-Making*
Gene Expression Profiling*/instrumentation
Breast Neoplasms/*diagnosis
Breast Neoplasms/*metabolism
Adult ; Aged ; Antineoplastic Agents, Hormonal/therapeutic use ; Breast Neoplasms/drug therapy ; Female ; Humans ; Middle Aged ; Receptors, Estrogen/metabolism ; Retrospective Studies ; Risk Assessment ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł:
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.
Autorzy:
Nickels S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Truong T
Hein R
Stevens K
Buck K
Behrens S
Eilber U
Schmidt M
Häberle L
Vrieling A
Gaudet M
Figueroa J
Schoof N
Spurdle AB
Rudolph A
Fasching PA
Hopper JL
Makalic E
Schmidt DF
Southey MC
Beckmann MW
Ekici AB
Fletcher O
Gibson L
Silva Idos S
Peto J
Humphreys MK
Wang J
Cordina-Duverger E
Menegaux F
Nordestgaard BG
Bojesen SE
Lanng C
Anton-Culver H
Ziogas A
Bernstein L
Clarke CA
Brenner H
Müller H
Arndt V
Stegmaier C
Brauch H
Brüning T
Harth V
Mannermaa A
Kataja V
Kosma VM
Hartikainen JM
Lambrechts D
Smeets D
Neven P
Paridaens R
Flesch-Janys D
Obi N
Wang-Gohrke S
Couch FJ
Olson JE
Vachon CM
Giles GG
Severi G
Baglietto L
Offit K
John EM
Miron A
Andrulis IL
Knight JA
Glendon G
Mulligan AM
Chanock SJ
Lissowska J
Liu J
Cox A
Cramp H
Connley D
Balasubramanian S
Dunning AM
Shah M
Trentham-Dietz A
Newcomb P
Titus L
Egan K
Cahoon EK
Rajaraman P
Sigurdson AJ
Doody MM
Guénel P
Pharoah PD
Schmidt MK
Hall P
Easton DF
Garcia-Closas M
Milne RL
Chang-Claude J
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Corporate Authors:
Genica Network
kConFab
AOCS Management Group
Źródło:
PLoS genetics [PLoS Genet] 2013; Vol. 9 (3), pp. e1003284. Date of Electronic Publication: 2013 Mar 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gene-Environment Interaction*
Genetic Association Studies*
Breast Neoplasms/*genetics
Alleles ; Breast Neoplasms/pathology ; Caspase 8/genetics ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Microfilament Proteins/genetics ; Middle Aged ; Polymorphism, Single Nucleotide ; Risk Factors ; White People
Czasopismo naukowe
Tytuł:
Efficacy of psychodynamic short-term psychotherapy for depressed breast cancer patients: study protocol for a randomized controlled trial.
Autorzy:
Zwerenz R; Department for Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany. />Beutel ME
Imruck BH
Wiltink J
Haselbacher A
Ruckes C
Schmidberger H
Hoffmann G
Schmidt M
Köhler U
Langanke D
Kortmann RD
Kuhnt S
Weissflog G
Barthel Y
Leuteritz K
Brähler E
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Źródło:
BMC cancer [BMC Cancer] 2012 Dec 05; Vol. 12, pp. 578. Date of Electronic Publication: 2012 Dec 05.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*psychology
Breast Neoplasms/*therapy
Depression/*etiology
Depression/*therapy
Psychotherapy, Brief/*methods
Adolescent ; Adult ; Aged ; Comorbidity ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Prospective Studies ; Quality of Life ; Young Adult
Czasopismo naukowe
Tytuł:
Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients.
Autorzy:
Siggelkow W; Department of Obstetrics and Gynecology, Diakonischen Dienste Hannover GmbH, Diakoniekrankenhaus Henriettenstiftung und Diakoniekrankenhaus Friederikenstift, Hanover, Germany.
Boehm D
Gebhard S
Battista M
Sicking I
Lebrecht A
Solbach C
Hellwig B
Rahnenführer J
Koelbl H
Gehrmann M
Marchan R
Cadenas C
Hengstler JG
Schmidt M
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2012 Nov 27; Vol. 12, pp. 562. Date of Electronic Publication: 2012 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms/*enzymology
Breast Neoplasms/*pathology
Protein Serine-Threonine Kinases/*biosynthesis
Aurora Kinase A ; Aurora Kinases ; Breast Neoplasms/genetics ; Disease-Free Survival ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Neoplasm Metastasis ; Prognosis ; Protein Serine-Threonine Kinases/genetics ; Receptor, ErbB-2/biosynthesis ; Receptor, ErbB-2/genetics ; Receptors, Estrogen/genetics ; Transcriptome
Czasopismo naukowe
Tytuł:
RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development.
Autorzy:
Thaler S; Centre for Biomedicine and Medical Technology Mannheim (CBTM), University of Heidelberg, Mannheim, Germany. />Schmidt M
Schad A
Sleeman JP
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Źródło:
Oncogene [Oncogene] 2012 Nov 22; Vol. 31 (47), pp. 4912-22. Date of Electronic Publication: 2012 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Signal Transduction*
Breast Neoplasms/*metabolism
Estrogen Receptor alpha/*genetics
Tumor Suppressor Proteins/*physiology
Animals ; Apoptosis ; Breast Neoplasms/pathology ; Cell Cycle Checkpoints ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Proliferation ; Cell Survival ; Cellular Senescence ; Estradiol/analogs & derivatives ; Estradiol/pharmacology ; Estrogen Antagonists/pharmacology ; Estrogen Receptor alpha/metabolism ; Estrogens/pharmacology ; Female ; Fulvestrant ; Gene Expression ; Humans ; MCF-7 Cells ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplasm Transplantation ; Proteolysis ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
Decentral gene expression analysis: analytical validation of the Endopredict genomic multianalyte breast cancer prognosis test.
Autorzy:
Kronenwett R; Sividon Diagnostics GmbH, Nattermannallee 1, 50829, Cologne, Germany. />Bohmann K
Prinzler J
Sinn BV
Haufe F
Roth C
Averdick M
Ropers T
Windbergs C
Brase JC
Weber KE
Fisch K
Müller BM
Schmidt M
Filipits M
Dubsky P
Petry C
Dietel M
Denkert C
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Źródło:
BMC cancer [BMC Cancer] 2012 Oct 05; Vol. 12, pp. 456. Date of Electronic Publication: 2012 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Breast Neoplasms/*genetics
Gene Expression Profiling/*methods
Pathology, Molecular/*methods
RNA/*analysis
Breast Neoplasms/pathology ; Female ; Humans ; Prognosis ; Real-Time Polymerase Chain Reaction ; Reproducibility of Results ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł:
Immunoglobulin kappa C predicts overall survival in node-negative breast cancer.
Autorzy:
Chen Z; Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany.
Gerhold-Ay A
Gebhard S
Boehm D
Solbach C
Lebrecht A
Battista M
Sicking I
Cotarelo C
Cadenas C
Marchan R
Stewart JD
Gehrmann M
Koelbl H
Hengstler JG
Schmidt M
Pokaż więcej
Źródło:
PloS one [PLoS One] 2012; Vol. 7 (9), pp. e44741. Date of Electronic Publication: 2012 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Immunoglobulin kappa-Chains/*metabolism
Disease-Free Survival ; Female ; Humans ; Immunohistochemistry ; Middle Aged
Czasopismo naukowe

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