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Wyświetlanie 1-20 z 2613
Tytuł:
The Osteocyte with SB216763-Activated Canonical Wnt Signaling Constructs a Multifunctional 4D Intelligent Osteogenic Module.
Autorzy:
Zhang J; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
Zhang Y; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
Chen J; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
Gong W; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
Tu X; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 15; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Osteogenesis*/physiology
Wnt Signaling Pathway*
Indoles*
Maleimides*
Osteocytes ; Bone and Bones ; Tissue Engineering/methods ; Cell Differentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, anticancer activity, and molecular docking of half-sandwich iron(II) cyclopentadienyl complexes with maleimide and phosphine or phosphite ligands.
Autorzy:
Das S; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland.
Strachanowska M; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Wadowski P; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Juszczak M; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Tokarz P; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland.
Kosińska A; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland.
Palusiak M; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Rybarczyk-Pirek AJ; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Wzgarda-Raj K; Department of Physical Chemistry, University of Lodz, Faculty of Chemistry, Pomorska 163/165, 90-236, Lodz, Poland.
Vasudevan S; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363, Lodz, Poland.
Chworos A; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363, Lodz, Poland.
Woźniak K; Department of Molecular Genetics, University of Lodz, Faculty of Biology and Environmental Protection, Pomorska 141/143, 90-236, Lodz, Poland. .
Rudolf B; Department of Organic Chemistry, University of Lodz, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5634. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Phosphites*
Coordination Complexes*/chemistry
Carcinoma, Non-Small-Cell Lung*
Lung Neoplasms*
Antineoplastic Agents*/chemistry
Phosphines*
Humans ; Molecular Docking Simulation ; Iron ; Leukocytes, Mononuclear/metabolism ; Spectroscopy, Fourier Transform Infrared ; DNA/metabolism ; Maleimides ; Ferrous Compounds/pharmacology ; Ligands ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitory effects of a maleimide compound on the virulence factors of Candida albicans .
Autorzy:
Li Y; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.
Chen C; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.
Cong L; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.
Mao S; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.
Shan M; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.; Clinical Laboratory, The Central Hospital of Xuzhou City, Xuzhou, China.
Han Z; Department of Genetics, Xuzhou Medical University, Xuzhou, China.
Mao J; Department of Genetics, Xuzhou Medical University, Xuzhou, China.
Xie Z; Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, Institute of Surface Micro and Nano Materials, College of Chemical and Materials Engineering, Xuchang University, Xuchang, China.
Zhu Z; Department of Genetics, Xuzhou Medical University, Xuzhou, China.
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Źródło:
Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2230009.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Candida albicans*/metabolism
Candidiasis*/microbiology
Animals ; Humans ; Virulence Factors/metabolism ; Farnesol/pharmacology ; Antifungal Agents/therapeutic use ; Maleimides/metabolism ; Maleimides/pharmacology ; Maleimides/therapeutic use ; Biofilms ; Hyphae
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of a N -Maleimide-derivatized Phosphatidylethanolamine on the Architecture and Properties of Lipid Bilayers.
Autorzy:
Ballesteros U; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
González-Ramirez EJ; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
de la Arada I; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
Sot J; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
Etxaniz A; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
Goñi FM; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
Alonso A; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
Montes LR; Department of Biochemistry, Instituto Biofisika (CSIC, UPV/EHU), University of the Basque Country, 48940 Leioa, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 21; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Lipid Bilayers*/chemistry
Phosphatidylethanolamines*/chemistry
Phospholipids/chemistry ; Membranes ; Maleimides ; Calorimetry, Differential Scanning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recyclization of Maleimides by Binucleophiles as a General Approach for Building Hydrogenated Heterocyclic Systems.
Autorzy:
Vandyshev DY; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, Universitetskaya Sq. 1, 394018 Voronezh, Russia.
Shikhaliev KS; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, Universitetskaya Sq. 1, 394018 Voronezh, Russia.; TekhnoKhim, 50 Let Sovetskoi Vlasti Str. 8, 394050 Voronezh, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 18; Vol. 27 (16). Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Maleimides*/chemistry
Cycloaddition Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
EK100 and Antrodin C Improve Brain Amyloid Pathology in APP/PS1 Transgenic Mice by Promoting Microglial and Perivascular Clearance Pathways.
Autorzy:
Tsay HJ; Institute of Neuroscience, School of Life Science, National Yang-Ming Chiao Tung University, Taipei 112, Taiwan.
Liu HK; National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 112, Taiwan.; Program in Clinical Drug Development of Chinese Medicine, Taipei Medical University, Taipei 112, Taiwan.
Kuo YH; Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan.; Department of Biotechnology, Asia University, Taichung 413, Taiwan.; Chinese Medicine Research Center, China Medical University, Taichung 404, Taiwan.
Chiu CS; Institute of Biopharmaceutical Science, National Yang-Ming Chiao Tung University, Taipei 112, Taiwan.
Liang CC; Institute of Anatomy and Cell Biology, National Yang-Ming Chiao Tung University, Taipei 112, Taiwan.
Chung CW; Institute of Traditional Medicine, National Yang-Ming Chiao Tung University, Taipei 112, Taiwan.
Chen CC; Biotech Research Institute, Grape King Bio Ltd., Taoyuan City 320, Taiwan.
Chen YP; Biotech Research Institute, Grape King Bio Ltd., Taoyuan City 320, Taiwan.
Shiao YJ; National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 112, Taiwan.; Program in Clinical Drug Development of Chinese Medicine, Taipei Medical University, Taipei 112, Taiwan.; Institute of Biopharmaceutical Science, National Yang-Ming Chiao Tung University, Taipei 112, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 27; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Maleimides*/chemistry
Maleimides*/pharmacology
Plaque, Amyloid*/drug therapy
Plaque, Amyloid*/genetics
Plaque, Amyloid*/metabolism
Amyloid beta-Protein Precursor/*metabolism
Microglia/*metabolism
Polyporales/*chemistry
Presenilin-1/*metabolism
Amyloid beta-Protein Precursor/genetics ; Animals ; Cell Line ; Mice ; Mice, Transgenic ; Microglia/pathology ; Presenilin-1/genetics
SCR Organism:
Taiwanofungus camphoratus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diverse Synthesis of Fused Polyheterocyclic Compounds via [3 + 2] Cycloaddition of In Situ-Generated Heteroaromatic N -Ylides and Electron-Deficient Olefins.
Autorzy:
Wang ZH; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Zhang T; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Shen LW; College of Chemistry and Chemical Engineering, Zunyi Normal University, Zunyi 563006, China.
Yang X; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Zhang YP; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
You Y; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Zhao JQ; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Yuan WC; Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 29; Vol. 28 (11). Date of Electronic Publication: 2023 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Alkenes*
Electrons*
Cycloaddition Reaction ; Stereoisomerism ; Maleimides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.
Autorzy:
Mulcrone PL; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Lam AK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Frabutt D; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Zhang J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Chrzanowski M; Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.
Herzog RW; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Xiao W; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 25; Vol. 13 (1), pp. 8436. Date of Electronic Publication: 2023 May 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Capsid*/chemistry
Capsid Proteins*/chemistry
Mice ; Animals ; Genetic Engineering ; Tropism ; Maleimides ; Dependovirus/genetics ; Genetic Vectors/genetics ; Transduction, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Desymmetrization of Prochiral N -Pyrazolyl Maleimides via Organocatalyzed Asymmetric Michael Addition with Pyrazolones: Construction of Tri- N -Heterocyclic Scaffolds Bearing Both Central and Axial Chirality.
Autorzy:
Geng J; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
Wei X; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
He B; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
Hao Y; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
Qu J; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
Wang B; State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 23; Vol. 28 (11). Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Thiourea*
Pyrazolones*
Molecular Structure ; Maleimides ; Stereoisomerism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BF 3 -OEt 2 Catalyzed C3-Alkylation of Indole: Synthesis of Indolylsuccinimidesand Their Cytotoxicity Studies.
Autorzy:
Shaikh IN; Department of Chemistry, Poona College of Arts, Science and Commerce, Camp, Pune 411 001, India.
Rahim A; Department of Chemistry, Poona College of Arts, Science and Commerce, Camp, Pune 411 001, India.
Faazil S; Department of Chemistry, Poona College of Arts, Science and Commerce, Camp, Pune 411 001, India.
Adil SF; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Assal ME; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Hatshan MR; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 11; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*chemical synthesis
Cyclin-Dependent Kinase 2/*antagonists & inhibitors
Indoles/*chemical synthesis
Maleimides/*chemical synthesis
Succinimides/*chemical synthesis
A549 Cells ; Alkylation ; Antineoplastic Agents/pharmacology ; Binding Sites ; Catalysis ; Cyclin-Dependent Kinase 2/chemistry ; Cyclin-Dependent Kinase 2/genetics ; Cyclin-Dependent Kinase 2/metabolism ; HT29 Cells ; Hep G2 Cells ; Humans ; Indoles/pharmacology ; Kinetics ; Maleimides/pharmacology ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Structure-Activity Relationship ; Substrate Specificity ; Succinimides/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reversible Diels-Alder Reactions with a Fluorescent Dye on the Surface of Magnetite Nanoparticles.
Autorzy:
He S; Inorganic Solid-State Chemistry, Saarland University, Campus Building C4 1, 66123 Saarbrücken, Germany.
Kickelbick G; Inorganic Solid-State Chemistry, Saarland University, Campus Building C4 1, 66123 Saarbrücken, Germany.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 07; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Fluorescent Dyes/*chemistry
Magnetite Nanoparticles/*chemistry
Maleimides/*chemistry
Cycloaddition Reaction ; Inorganic Chemicals/chemistry ; Maleimides/chemical synthesis ; Rhodamines/chemistry ; Surface Properties/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Study on the Interaction Mechanism of Methoxy Polyethylene Glycol Maleimide with Sweet Potato β-Amylase.
Autorzy:
Liang X; Henan Institute of Science and Technology, School of Food Science, Xinxiang 453003, China.
Kong Y; Henan Institute of Science and Technology, School of Food Science, Xinxiang 453003, China.
Sun H; Xinxiang Institute of Engineering, School of Food Engineering, Xinxiang 453003, China.
Zhao R; Henan Institute of Science and Technology, School of Food Science, Xinxiang 453003, China.
Jiao L; Henan Institute of Science and Technology, School of Food Science, Xinxiang 453003, China.
Zhang W; Henan Institute of Science and Technology, School of Food Science, Xinxiang 453003, China.
Liu B; Xinxiang Institute of Engineering, School of Food Engineering, Xinxiang 453003, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 27; Vol. 28 (5). Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Ipomoea batatas*
beta-Amylase*
Circular Dichroism ; Thermodynamics ; Polyethylene Glycols ; Maleimides ; Protein Binding ; Spectrometry, Fluorescence/methods ; Binding Sites ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Improving the Stability of Maleimide-Thiol Conjugation for Drug Targeting.
Autorzy:
Lahnsteiner M; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Kastner A; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Mayr J; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Roller A; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Keppler BK; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Waehringer Strasse 42, 1090, Vienna, Austria.
Kowol CR; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Waehringer Strasse 42, 1090, Vienna, Austria.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Dec 04; Vol. 26 (68), pp. 15867-15870. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoconjugates*/chemistry
Maleimides*/chemistry
Sulfhydryl Compounds*/chemistry
Cyclization ; Drug Delivery Systems ; Drug Stability ; Succinimides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 2613

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