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Wyszukujesz frazę ""MAP Kinase Signaling System"" wg kryterium: Temat


Tytuł :
The inflammatory signalling mediator TAK1 mediates lymphocyte recruitment to lipopolysaccharide-activated murine mesenchymal stem cells through interleukin-6.
Autorzy :
Oelze B; Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, 38124, Braunschweig, Germany.
Elger K; Hannover Medical School, Department of Orthopaedic Surgery, Graded Implants and Regenerative Strategies OE 8893, Stadtfelddamm 34, 30625, Hannover, Germany.; Hannover Medical School, Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Stadtfelddamm 34, 30625, Hannover, Germany.
Schadzek P; Hannover Medical School, Department of Orthopaedic Surgery, Graded Implants and Regenerative Strategies OE 8893, Stadtfelddamm 34, 30625, Hannover, Germany.; Hannover Medical School, Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Stadtfelddamm 34, 30625, Hannover, Germany.
Burmeister L; Hannover Medical School, Department of Orthopaedic Surgery, Graded Implants and Regenerative Strategies OE 8893, Stadtfelddamm 34, 30625, Hannover, Germany.; Hannover Medical School, Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Stadtfelddamm 34, 30625, Hannover, Germany.
Hamm A; Hannover Medical School, Department of Orthopaedic Surgery, Graded Implants and Regenerative Strategies OE 8893, Stadtfelddamm 34, 30625, Hannover, Germany.; Hannover Medical School, Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Stadtfelddamm 34, 30625, Hannover, Germany.
Laggies S; Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, 38124, Braunschweig, Germany.
Seiffart V; Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, 38124, Braunschweig, Germany.
Gross G; Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, 38124, Braunschweig, Germany.
Hoffmann A; Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, 38124, Braunschweig, Germany. .; Hannover Medical School, Department of Orthopaedic Surgery, Graded Implants and Regenerative Strategies OE 8893, Stadtfelddamm 34, 30625, Hannover, Germany. .; Hannover Medical School, Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Stadtfelddamm 34, 30625, Hannover, Germany. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Oct; Vol. 476 (10), pp. 3655-3670. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-6/*immunology
Lipopolysaccharides/*pharmacology
Lymphocytes/*immunology
MAP Kinase Kinase Kinases/*immunology
MAP Kinase Signaling System/*drug effects
Mesenchymal Stem Cells/*immunology
Animals ; HEK293 Cells ; Humans ; Interleukin-6/genetics ; MAP Kinase Kinase Kinases/genetics ; MAP Kinase Signaling System/genetics ; MAP Kinase Signaling System/immunology ; Mice
Czasopismo naukowe
Tytuł :
Central, but not peripheral, nervous system ERK2 is essential for itch signals in murine allergic skin inflammation.
Autorzy :
Matsuo S; Department of Dermatology, National Defense Medical College, Tokorozawa, Japan.
Hashimoto T; Department of Dermatology, National Defense Medical College, Tokorozawa, Japan.
Matsuura F; Department of Anesthesiology, National Defense Medical College, Tokorozawa, Japan.
Imamura O; Department of Biochemistry, National Defense Medical College, Tokorozawa, Japan.
Endo S; Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Satoh Y; Department of Biochemistry, National Defense Medical College, Tokorozawa, Japan.
Satoh T; Department of Dermatology, National Defense Medical College, Tokorozawa, Japan.
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Źródło :
Allergy [Allergy] 2021 Nov; Vol. 76 (11), pp. 3422-3432. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MAP Kinase Signaling System*
Mitogen-Activated Protein Kinase 1*/genetics
Pruritus*
Animals ; Disease Models, Animal ; Inflammation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Peripheral Nervous System ; Skin
Czasopismo naukowe
Tytuł :
Eukaryotic initiation factor-2, gamma subunit, suppresses proliferation and regulates the cell cycle via the MAPK/ERK signaling pathway in acute myeloid leukemia.
Autorzy :
Lu J; Department of Pediatrics, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.; Department of Urology and Minimally Invasive Surgery Center, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Urology, Guangzhou, 510230, Guangdong, People's Republic of China.
Chen S; Department of Hematology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.; Department of Urology and Minimally Invasive Surgery Center, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Urology, Guangzhou, 510230, Guangdong, People's Republic of China.
Tan H; Department of Hematology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.
Huang Z; Department of Hematology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.
Li B; Department of Pediatrics, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.
Liu L; Department of Hematology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 51260, People's Republic of China.
Chen Y; Department of Hematology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.
Zeng X; Department of Pediatrics, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China.
Zou Y; Department of Pediatrics, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China. .
Xu L; Department of Hematology, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang West Road, Yuexiu, Guangzhou, 510000, Guangdong, People's Republic of China. .; Department of Urology and Minimally Invasive Surgery Center, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Urology, Guangzhou, 510230, Guangdong, People's Republic of China. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Nov; Vol. 147 (11), pp. 3157-3168. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Eukaryotic Initiation Factor-2/*metabolism
Leukemia, Myeloid, Acute/*metabolism
Animals ; Carcinogenesis ; Cell Cycle/physiology ; Cell Line, Tumor ; Cell Proliferation/physiology ; Eukaryotic Initiation Factor-2/biosynthesis ; Eukaryotic Initiation Factor-2/genetics ; HL-60 Cells ; Heterografts ; Humans ; Leukemia, Myeloid, Acute/enzymology ; Leukemia, Myeloid, Acute/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Phosphorylation ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
The ERK-p38MAPK-STAT3 Signalling Axis Regulates iNOS Expression and Salmonella Infection in Senescent Cells.
Autorzy :
Fernandes SE; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.
Saini DK; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.; Center For BioSystems Science and Engineering, Indian Institute of Science, Bangalore, India.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Oct 22; Vol. 11, pp. 744013. Date of Electronic Publication: 2021 Oct 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MAP Kinase Signaling System*
Salmonella Infections*
Cellular Senescence ; Humans ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; STAT3 Transcription Factor ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
17β-Estradiol Enhances Porcine Meiosis Resumption from Autophagy-Induced Gap Junction Intercellular Communications and Connexin 43 Phosphorylation via the MEK/ERK Signaling Pathway.
Autorzy :
Duan J; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Chen H; School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, Sichuan 621000, People's Republic of China.
Li Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Xu D; College of Animal Science and Technology, Southwest University, Chongqing, Sichuan 400000, People's Republic of China.
Li X; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Zhang Z; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Cheng J; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Yang L; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
Li Q; College of Animal Science and Technology, Northwest A&F University, Yangling, Xianyang, Shaanxi 712100, People's Republic of China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Oct 13; Vol. 69 (40), pp. 11847-11855. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Connexin 43*/genetics
Connexin 43*/metabolism
MAP Kinase Signaling System*
Animals ; Autophagy ; Estradiol/metabolism ; Estradiol/pharmacology ; Female ; Gap Junctions/metabolism ; Meiosis ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Oocytes/metabolism ; Phosphorylation ; Signal Transduction ; Swine
Czasopismo naukowe
Tytuł :
Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway.
Autorzy :
Zhang Y; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zhang L; Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Chen W; Department of Pathology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zhang Y; Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Wang X; Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Dong Y; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zhang W; Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: .
Lin X; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Oct 10; Vol. 350, pp. 62-70. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*/drug effects
Acute Lung Injury/*metabolism
Acute Lung Injury/*physiopathology
Epithelial Cells/*metabolism
Particulate Matter/*toxicity
Tight Junction Proteins/*metabolism
src Homology Domains/*drug effects
Animals ; Epithelial Cells/drug effects ; Humans ; Male ; Mice ; Mice, Inbred ICR ; Models, Animal ; Tight Junction Proteins/drug effects
Czasopismo naukowe
Tytuł :
[Guanxin Zhitong Capsules attenuate human endothelial cell damage induced by palmitic acid via MAPK signaling pathway].
Autorzy :
Wang XL; Henan Academy of Chinese Medicine Zhengzhou 450004, China.
Shao J; the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China.
Wu GX; the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China.
Zhang W; Henan Academy of Chinese Medicine Zhengzhou 450004, China.
Zhou HY; Henan Academy of Chinese Medicine Zhengzhou 450004, China.
Li KY; Henan Academy of Chinese Medicine Zhengzhou 450004, China.
Sun W; Henan Academy of Chinese Medicine Zhengzhou 450004, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2021 Oct; Vol. 46 (19), pp. 5096-5102.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Palmitic Acid*/toxicity
Apoptosis ; Capsules ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Signal Transduction ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures.
Autorzy :
Foster SL; Department of Human Genetics, Emory University School of Medicine, 615 Michael St., Whitehead 301, Atlanta, GA, 30322, USA.
Lustberg DJ; Department of Human Genetics, Emory University School of Medicine, 615 Michael St., Whitehead 301, Atlanta, GA, 30322, USA.
Harbin NH; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, 1510 Clifton Rd, Atlanta, GA, 30322, USA.
Bramlett SN; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, 1510 Clifton Rd, Atlanta, GA, 30322, USA.
Hepler JR; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, 1510 Clifton Rd, Atlanta, GA, 30322, USA. .
Weinshenker D; Department of Human Genetics, Emory University School of Medicine, 615 Michael St., Whitehead 301, Atlanta, GA, 30322, USA. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2021 Oct; Vol. 238 (10), pp. 2755-2773. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Central Nervous System Stimulants*
Cocaine*/pharmacology
MAP Kinase Signaling System*
RGS Proteins*/metabolism
Animals ; Hippocampus/metabolism ; Mice ; Mice, Knockout ; Proto-Oncogene Proteins c-fos/metabolism
Czasopismo naukowe
Tytuł :
Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial-mesenchymal transition via the MEK/ERK pathway.
Autorzy :
Li N; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.; Institute of Digestive Disease, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xu X; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yang H; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Wang H; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ouyang Y; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhou Y; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Peng C; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yuan Z; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
He C; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zeng C; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Hong J; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
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Źródło :
Helicobacter [Helicobacter] 2021 Oct; Vol. 26 (5), pp. e12842. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Helicobacter Infections*
Helicobacter pylori*/metabolism
MAP Kinase Signaling System*
Stomach Neoplasms*
Antigens, Bacterial/metabolism ; Aquaporin 5/genetics ; Bacterial Proteins/metabolism ; Carcinogenesis ; Carcinogens ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition ; Gastric Mucosa/metabolism ; Humans ; Mitogen-Activated Protein Kinase Kinases
Czasopismo naukowe
Tytuł :
High MEK/ERK signalling is a key regulator of diapause maintenance in the cotton bollworm, Helicoverpa armigera.
Autorzy :
Lin XW; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Fan ZZ; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Liu YH; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Li J; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Ma Q; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Yan RH; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
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Źródło :
Insect molecular biology [Insect Mol Biol] 2021 Oct; Vol. 30 (5), pp. 508-518. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diapause, Insect*
MAP Kinase Signaling System*
Moths*/physiology
Animals ; Mitogen-Activated Protein Kinase Kinases ; Pupa ; Reactive Oxygen Species ; Ubiquitins
Czasopismo naukowe
Tytuł :
African pygmy hedgehog adenovirus: Virus replication, virus-induced cytopathogenesis and activation of mitogen-activated protein kinase signaling pathways in infected MDCK cells.
Autorzy :
Wen R; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Ochiai H; Research Institute of Biosciences, Azabu University, Sagamihara, Kanagawa, Japan.
Uchiyama J; Laboratory of Microbiology, Azabu University, Sagamihara, Kanagawa, Japan.
Osawa N; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Oba M; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Katayama Y; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Li K; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Omatsu T; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan.
Tamukai K; Denenchofu Animal Hospital, Ota, Tokyo, Japan.
Suzuki K; Field Science Center, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Madarame H; Laboratory of Small Animal Clinics, Veterinary Teaching Hospital, Azabu University, Sagamihara, Kanagawa, Japan.
Makino S; Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, TX, USA.
Mizutani T; Center for Infectious Diseases Epidemiology and Prevention Research, Fuchu, Tokyo, Japan. Electronic address: .
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Źródło :
Research in veterinary science [Res Vet Sci] 2021 Oct; Vol. 139, pp. 152-158. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Adenoviridae*/genetics
JNK Mitogen-Activated Protein Kinases*/metabolism
MAP Kinase Signaling System*
Virus Replication*
Animals ; Apoptosis ; Dogs ; Hedgehogs/metabolism ; Madin Darby Canine Kidney Cells ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
A non-translational role of threonyl-tRNA synthetase in regulating JNK signaling during myogenic differentiation.
Autorzy :
Dai C; Department of Cell & Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Reyes-Ordoñez A; Department of Cell & Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
You JS; Department of Cell & Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Chen J; Department of Cell & Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Oct; Vol. 35 (10), pp. e21948.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
MAP Kinase Signaling System*
Muscle Development*
JNK Mitogen-Activated Protein Kinases/*metabolism
Threonine-tRNA Ligase/*metabolism
Animals ; Axin Protein/metabolism ; Female ; MAP Kinase Kinase 4/metabolism ; MAP Kinase Kinase Kinase 4/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Protein Binding ; Protein Biosynthesis ; Protein Domains ; Threonine-tRNA Ligase/chemistry
Czasopismo naukowe
Tytuł :
MiR-145 regulates steroidogenesis in mouse primary granulosa cells through targeting Crkl.
Autorzy :
Wang S; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Tang W; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Ma L; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China; Department of Obstetrics and Gynecology, Guiyang Maternity and Child Health Care Hospital, Guiyang, Guizhou, People's Republic of China.
Yang J; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China; Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing, People's Republic of China.
Huang K; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Du X; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China; Department of Obstetrics and Gynecology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Luo A; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Shen W; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Ding T; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Ye S; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Zhou S; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Yang S; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. Electronic address: .
Wang S; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119820. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Cell Proliferation*
Down-Regulation*
MAP Kinase Signaling System*
Adaptor Proteins, Signal Transducing/*biosynthesis
Granulosa Cells/*metabolism
MicroRNAs/*biosynthesis
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Female ; Mice ; MicroRNAs/genetics
Czasopismo naukowe
Tytuł :
β2 -Adrenoceptor Agonists Promote Extracellular Signal-Regulated Kinase 1/2 Dephosphorylation in Human Airway Epithelial Cells by Canonical, cAMP-Driven Signaling Independently of β -Arrestin 2.
Autorzy :
Hamed O; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Joshi R; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Michi AN; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Kooi C; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Giembycz MA; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2021 Oct; Vol. 100 (4), pp. 388-405. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adrenergic beta-2 Receptor Agonists/*pharmacology
Cyclic AMP/*metabolism
MAP Kinase Signaling System/*physiology
Receptors, Adrenergic, beta-2/*metabolism
Respiratory Mucosa/*metabolism
beta-Arrestin 2/*metabolism
Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; MAP Kinase Signaling System/drug effects ; Phosphorylation/drug effects ; Phosphorylation/physiology ; Respiratory Mucosa/drug effects ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Molecular basis of Period 1 regulation by adrenergic signaling in the heart.
Autorzy :
Jesus ICG; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Araújo FM; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Mesquita T; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Júnior NNS; Department of Physiology, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil.
Silva MM; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Morgan HJN; Department of Physiology, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil.
Silva KSC; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Silva CLA; Animal Facility of Blood Center Foundation, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil.
Birbrair A; Department of Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Amaral FA; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Navegantes LC; Department of Physiology, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil.
Salgado HC; Department of Physiology, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil.
Szawka RE; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Poletini MO; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Guatimosim S; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Oct; Vol. 35 (10), pp. e21886.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
MAP Kinase Signaling System*
Myocardium/*metabolism
Period Circadian Proteins/*biosynthesis
Receptors, Adrenergic, beta-2/*metabolism
ARNTL Transcription Factors/biosynthesis ; ARNTL Transcription Factors/genetics ; Adrenergic beta-2 Receptor Antagonists/pharmacology ; Animals ; CLOCK Proteins/biosynthesis ; Isoproterenol/pharmacology ; Male ; Mice ; Mice, Knockout ; Period Circadian Proteins/genetics ; Receptors, Adrenergic, beta-2/genetics
Czasopismo naukowe
Tytuł :
Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways.
Autorzy :
Sevilla LM; Instituto de Biomedicina de Valencia (IBV)-CSIC, 46010 Valencia, Spain.
Jiménez-Panizo A; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona (UB), 08028 Barcelona, Spain.; Institute of Biomedicine, University of Barcelona (IBUB), 08028 Barcelona, Spain.
Alegre-Martí A; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona (UB), 08028 Barcelona, Spain.; Institute of Biomedicine, University of Barcelona (IBUB), 08028 Barcelona, Spain.
Estébanez-Perpiñá E; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona (UB), 08028 Barcelona, Spain.; Institute of Biomedicine, University of Barcelona (IBUB), 08028 Barcelona, Spain.
Caelles C; Institute of Biomedicine, University of Barcelona (IBUB), 08028 Barcelona, Spain.; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, University of Barcelona (UB), 08028 Barcelona, Spain.
Pérez P; Instituto de Biomedicina de Valencia (IBV)-CSIC, 46010 Valencia, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Expression Regulation*
MAP Kinase Signaling System*
Glucocorticoids/*metabolism
Receptors, Glucocorticoid/*genetics
Receptors, Glucocorticoid/*metabolism
Animals ; Autoimmune Diseases/therapy ; Chronic Disease ; Enzyme Activation ; Heterozygote ; Humans ; Inflammation/metabolism ; Leukemia/therapy ; Metabolism, Inborn Errors/metabolism ; Mice ; Mutation ; Polymorphism, Genetic ; Protein Isoforms ; Receptors, Glucocorticoid/deficiency ; Respiration Disorders/therapy ; Signal Transduction ; Skin Diseases/therapy ; Treatment Outcome
SCR Disease Name :
Glucocorticoid Receptor Deficiency
Czasopismo naukowe
Tytuł :
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Autorzy :
Brägelmann J; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .; Mildred Scheel School of Oncology Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .
Lorenz C; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Borchmann S; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Else-Kröner-Forschungskolleg Clonal Evolution in Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Nishii K; Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Wegner J; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Meder L; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Mildred Scheel School of Oncology Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Ostendorp J; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Ast DF; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Mildred Scheel School of Oncology Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Heimsoeth A; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Nakasuka T; Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hirabae A; Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Okawa S; Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Dammert MA; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Plenker D; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, NY, 11724, USA.
Klein S; Else-Kröner-Forschungskolleg Clonal Evolution in Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Lohneis P; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Gu J; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.
Godfrey LK; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.
Forster J; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; Genome Informatics, Institute of Human Genetics, University Duisburg-Essen, Essen, Germany.
Trajkovic-Arsic M; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.
Zillinger T; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Haarmann M; Mildred Scheel School of Oncology Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Quaas A; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Lennartz S; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Schmiel M; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
D'Rozario J; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Thomas ES; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Imperial College London, London, UK.
Li H; Crown Bioscience, San Diego, CA, USA.
Schmitt CA; Department of Hematology, Oncology and Tumor Immunology, Charité - University Medical Center, Virchow Campus, and Molekulares Krebsforschungszentrum, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Department of Hematology and Oncology, Kepler University Hospital, Johannes Kepler University, Linz, Austria.
George J; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department of Head and Neck Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Thomas RK; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; German Cancer Research Center, German Cancer Consortium (DKTK), Heidelberg, Germany.
von Karstedt S; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Hartmann G; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Büttner R; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Ullrich RT; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Siveke JT; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.
Ohashi K; Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.; Department of Respiratory Medicine, Okayama University Hospital, Japan, 2-5-1 Shikata-cho, Kitaku, Okayama, 700-8558, Japan.
Schlee M; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Sos ML; Molecular Pathology, Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 17; Vol. 12 (1), pp. 5505. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*/drug effects
MAP Kinase Signaling System*/drug effects
DEAD Box Protein 58/*metabolism
Inflammation/*pathology
Neoplasms/*metabolism
Protein Kinase Inhibitors/*pharmacology
Receptors, Immunologic/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Cycle Checkpoints/drug effects ; Cell Death/drug effects ; Cell Line, Tumor ; Cytokines/metabolism ; ErbB Receptors/metabolism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Immune Evasion/drug effects ; Interferon Regulatory Factor-1/metabolism ; Mice ; Mice, Inbred C57BL ; Neoplasms/pathology ; Oncogenes ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Orexin-A Regulates Follicular Growth, Proliferation, Cell Cycle and Apoptosis in Mouse Primary Granulosa Cells via the AKT/ERK Signaling Pathway.
Autorzy :
Safdar M; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Liang A; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Rajput SA; Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of Agriculture, Multan 66000, Pakistan.; Department of Animal Nutrition and Feed Sciences, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Abbas N; Department of Animal Breeding & Genetics, PMAS-Arid Agriculture University, Rawalpindi 46300, Pakistan.
Zubair M; Key Laboratory of Agricultural Microbiology, Education Ministry of China, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Shaukat A; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Rehman AU; Department of Pathobiology, University of Veterinary and Animal Sciences, Jhang 35200, Pakistan.
Jamil H; Department of Theriogenology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38000, Pakistan.
Guo Y; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Ullah F; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Yang L; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 16; Vol. 26 (18). Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Granulosa Cells/*metabolism
MAP Kinase Signaling System/*drug effects
Orexins/*physiology
Ovarian Follicle/*cytology
Ovarian Follicle/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Apoptosis/genetics ; Apoptosis/physiology ; Cell Cycle/genetics ; Cell Cycle/physiology ; Cell Proliferation/genetics ; Cell Proliferation/physiology ; Down-Regulation/genetics ; Female ; Granulosa Cells/drug effects ; Granulosa Cells/physiology ; MAP Kinase Signaling System/genetics ; Mice ; Orexin Receptors/genetics ; Orexin Receptors/metabolism ; Orexins/metabolism ; Ovarian Follicle/drug effects ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
The Protective Effect of Docosahexaenoic Acid on PC12 Cells in Oxidative Stress Induced by H 2 O 2 through the TrkB-Erk1/2-CREB Pathway.
Autorzy :
Bie N; 'State Key Laboratory of Food Nutrition and Safety', Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, People's Republic of China.
Feng X; 'State Key Laboratory of Food Nutrition and Safety', Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, People's Republic of China.
Li C; 'State Key Laboratory of Food Nutrition and Safety', Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, People's Republic of China.
Meng M; 'State Key Laboratory of Food Nutrition and Safety', Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, People's Republic of China.
Wang C; 'State Key Laboratory of Food Nutrition and Safety', Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, People's Republic of China.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Sep 15; Vol. 12 (18), pp. 3433-3444. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclic AMP Response Element-Binding Protein*/metabolism
MAP Kinase Signaling System*
Animals ; Docosahexaenoic Acids/pharmacology ; Hydrogen Peroxide/toxicity ; Oxidative Stress ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling.
Autorzy :
Scully T; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY, 10029, USA.
Kase N; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY, 10029, USA.
Gallagher EJ; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY, 10029, USA. .; Tisch Cancer Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA. .
LeRoith D; Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY, 10029, USA.; Tisch Cancer Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.
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Źródło :
Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 17927. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
ErbB Receptors/*metabolism
MAP Kinase Signaling System/*genetics
Mitogen-Activated Protein Kinases/*metabolism
Receptors, LDL/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Animals ; Butadienes/pharmacology ; Cell Line, Tumor ; Epidermal Growth Factor/pharmacology ; Female ; Gene Silencing ; Humans ; MAP Kinase Signaling System/drug effects ; Mice ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Nitriles/pharmacology ; Phosphorylation/drug effects ; RNA, Messenger/genetics ; Ribosomal Protein S6 Kinases, 90-kDa/genetics ; Ribosomal Protein S6 Kinases, 90-kDa/metabolism ; Transfection ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe

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