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Tytuł :
Allyl Isothiocyanate Induces DNA Damage and Impairs DNA Repair in Human Breast Cancer MCF-7 Cells.
Autorzy :
Liao CL; College of Chinese Medicine, School of Post-Baccalaureate Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C.
Peng SF; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chen JC; Department of Medicinal Botany and Health Applications, Da-Yeh University, Changhua, Taiwan, R.O.C.
Chen PY; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.
Huang AC; Department of Nursing, St. Mary's Junior College of Medicine, Nursing and Management, Yilan, Taiwan, R.O.C.
Lien JC; School of Pharmacy, China Medical University, Taichung, Taiwan, R.O.C.
Chueh FS; Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, R.O.C.
Chiang TA; Department of Medical Technology and Graduate Institute of Biological Science and Technology, College of Medicine and Life Science, Chung-Hwa University of Medical Technology, Tainan, Taiwan, R.O.C.
Wu PP; School of Pharmacy, China Medical University, Taichung, Taiwan, R.O.C.; .
Lin KI; Department of Obstetrics and Gynecology, Chang Bing Show-Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.; .; Department of Cosmetic Science, Providence University, Taichung, Taiwan, R.O.C.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4343-4351.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Breast Neoplasms/*genetics
DNA Repair/*drug effects
Isothiocyanates/*pharmacology
Breast Neoplasms/metabolism ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA Damage ; Dose-Response Relationship, Drug ; Female ; Gene Regulatory Networks/drug effects ; Humans ; MCF-7 Cells
Czasopismo naukowe
Tytuł :
Tetracationic porphyrin derivatives against human breast cancer.
Autorzy :
Gamelas SRD; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Moura NMM; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: .
Habraken Y; Laboratory of Gene Expression and Cancer, GIGA-Molecular Biology of Diseases, B34, University of Liège, Avenue de l'Hôpital 11, 4000 Liège, Belgium. Electronic address: .
Piette J; Laboratory of Virology and Immunology, GIGA-Molecular Biology of Diseases, GIGA B34, University of Liège, Avenue de l'Hôpital 11, 4000 Liège, Belgium.
Neves MGPMS; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Faustino MAF; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2021 Sep; Vol. 222, pp. 112258. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Photosensitizing Agents/*pharmacology
Porphyrins/*pharmacology
Apoptosis/radiation effects ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Female ; Humans ; Light ; MCF-7 Cells ; Microscopy, Confocal ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/therapeutic use ; Porphyrins/chemistry ; Porphyrins/therapeutic use ; Singlet Oxygen/metabolism
Czasopismo naukowe
Tytuł :
1H-benzimidazole-2-yl hydrazones as tubulin-targeting agents: Synthesis, structural characterization, anthelmintic activity and antiproliferative activity against MCF-7 breast carcinoma cells and molecular docking studies.
Autorzy :
Anichina K; University of Chemical Technology and Metallurgy, 8 Kliment Ohridski Blvd., 1756, Sofia, Bulgaria.
Argirova M; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., build. 9, 1113 Sofia, Bulgaria.
Tzoneva R; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria.
Uzunova V; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria.
Mavrova A; University of Chemical Technology and Metallurgy, 8 Kliment Ohridski Blvd., 1756, Sofia, Bulgaria.
Vuchev D; Departmant of Infectious Diseases, Parasitology and Tropical Medicine, Medical University, Plovdiv, Bulgaria.
Popova-Daskalova G; Departmant of Infectious Diseases, Parasitology and Tropical Medicine, Medical University, Plovdiv, Bulgaria.
Fratev F; Micar Innovation (Micar 21) Ltd., 34B Persenk Str., 1407, Sofia, Bulgaria; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Texas at El Paso, 1101 N Campbell St, El Paso, TX, 79968, USA.
Guncheva M; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., build. 9, 1113 Sofia, Bulgaria.
Yancheva D; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., build. 9, 1113 Sofia, Bulgaria. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Aug 25; Vol. 345, pp. 109540. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Benzimidazoles/*chemistry
Hydrazones/*chemistry
Hydrazones/*pharmacology
Tubulin/*metabolism
Anthelmintics/chemical synthesis ; Anthelmintics/chemistry ; Anthelmintics/metabolism ; Anthelmintics/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/pharmacology ; Cell Proliferation/drug effects ; Chemistry Techniques, Synthetic ; Drug Design ; Drug Screening Assays, Antitumor ; Humans ; Hydrazones/chemical synthesis ; Hydrazones/metabolism ; MCF-7 Cells ; Protein Conformation ; Structure-Activity Relationship ; Tubulin/chemistry ; Tubulin Modulators/chemical synthesis ; Tubulin Modulators/chemistry ; Tubulin Modulators/metabolism ; Tubulin Modulators/pharmacology
Czasopismo naukowe
Tytuł :
Five new complexes with deferiprone and N,N-donor ligands: evaluation of cytotoxicity against breast cancer MCF-7 cell line and HSA-binding determination.
Autorzy :
Delavar Mendi F; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Sh Saljooghi A; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Ramezani M; Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Kruszynski R; Department of X-ray Crystallography and Crystal Chemistry, Institute of General and Ecological Chemistry, Lodz University of Technology, Lodz, Poland.
Poupon M; Institute of Physics of the Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Kucerakova M; Institute of Physics of the Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Huch V; Faculty of Natural Sciences and Technology, Department of Chemistry, Saarland University, Saarbrücken, Germany.
Socha P; The Czochralski Laboratory of Advanced Crystal Engineering, Faculty of Chemistry, University of Warsaw, Warsaw, Poland.
Babaei M; Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Alibolandi M; Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Aug; Vol. 39 (13), pp. 4845-4858. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Breast Neoplasms*
Coordination Complexes*/pharmacology
Binding Sites ; DNA/metabolism ; Deferiprone ; Female ; Humans ; Ligands ; MCF-7 Cells ; Protein Binding ; Serum Albumin, Human/metabolism ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Tytuł :
A novel selective probe for detecting glutathione from other biothiols based on the concept of Fluorescence Fusion.
Autorzy :
Wang W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Wang K; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Wang XT; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Man RJ; Guangxi Biological Polysaccharide Separation, Purification and Modification Research Platform, Guangxi University for Nationalities, Nanning 530006, China.
Xu C; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China. Electronic address: .
Yang YS; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China. Electronic address: .
Zhu HL; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China. Electronic address: .
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2021 Sep 08; Vol. 1177, pp. 338786. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteine*
Glutathione*/isolation & purification
Artificial Intelligence ; Fluorescence ; Fluorescent Dyes ; Homocysteine ; Humans ; MCF-7 Cells
Czasopismo naukowe
Tytuł :
TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution.
Autorzy :
Yuan W; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Al-Hadid Q; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Wang Z; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Shen L; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Cho H; Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Wu X; Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
Yang Y; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope National Cancer Center, Duarte, CA 91010, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Sep 07; Vol. 49 (15), pp. 8573-8591.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
R-Loop Structures*
DEAD-box RNA Helicases/*metabolism
Neoplasm Proteins/*metabolism
Proteins/*metabolism
Chromatin ; DNA Topoisomerases, Type I/metabolism ; HEK293 Cells ; Humans ; MCF-7 Cells ; Protein Interaction Domains and Motifs ; Proteins/chemistry ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Putative N-glycoprotein markers of MCF-7/ADR cancer stem cells from N-glycoproteomics characterization of the whole cell lysate.
Autorzy :
Yang H; School of Chemical Science & Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092, China.
Xu F; School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.
Chen Y; School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China. Electronic address: .
Tian Z; School of Chemical Science & Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University, Shanghai, 200092, China. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Sep 01; Vol. 232, pp. 122437. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms*
Tandem Mass Spectrometry*
Biomarkers ; Female ; Glycopeptides ; Glycoproteins ; Humans ; MCF-7 Cells ; Neoplastic Stem Cells ; Proteomics
Czasopismo naukowe
Tytuł :
Cytotoxic Activity of Isoniazid Derivative in Human Breast Cancer Cells.
Autorzy :
Barathan M; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Zulpa AK; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Vellasamy KM; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Mariappan V; Center of Toxicology and Health Risk Studies (CORE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Shivashekaregowda NKH; School of Pharmacy, Taylor's University, Lakeside Campus, Selangor, Malaysia.
Ibrahim ZA; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Vadivelu J; Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia; .
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2021 Sep-Oct; Vol. 35 (5), pp. 2675-2685.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/drug therapy
Animals ; Apoptosis ; Cell Proliferation ; Cell Survival ; Female ; Humans ; Isoniazid/therapeutic use ; Isoniazid/toxicity ; MCF-7 Cells ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
Cytotoxicity, in vivo toxicity, and chemical composition of the hexane extract of Plectranthus amboinicus (Lour.) Spreng.
Autorzy :
Almalki A; National Center for Environmental Technology (NCET) King Abdulaziz City for Science and Technology (KACST), Life Sciences and Environment Research Institute (LSERI), Riyadh, 11442, Saudi Arabia.
Abutaha N; Department of Zoology College of Science, Bioproducts Research Chair King Saud University, Riyadh, 11451, Saudi Arabia. .
Al-Doaiss AA; Department of Biology College of Science, King Khalid University, Abha, Saudi Arabia.
Mohammed AZ; College of Science, Biology Department, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Wadaan MA; Department of Zoology College of Science, Bioproducts Research Chair King Saud University, Riyadh, 11451, Saudi Arabia.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Sep; Vol. 28 (35), pp. 48141-48153. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Plectranthus*
Animals ; Apoptosis ; Hexanes ; Humans ; MCF-7 Cells ; Mice ; Plant Extracts/toxicity ; Plant Leaves
Czasopismo naukowe
Tytuł :
Spatially localized amplification reaction with accelerated target conversion for sensitive microRNA detection.
Autorzy :
Qing M; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Chen SL; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Zhou J; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Luo HQ; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China. Electronic address: .
Li NB; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Sep 01; Vol. 232, pp. 122422. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques*
MicroRNAs*/genetics
Biological Assay ; DNA ; Entropy ; HeLa Cells ; Humans ; Limit of Detection ; MCF-7 Cells ; Nucleic Acid Amplification Techniques
Czasopismo naukowe
Tytuł :
Soluble Factors Involved in Cancer Cell-Macrophage Interaction Promote Breast Cancer Growth.
Autorzy :
Yonemitsu K; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Miyasato Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shiota T; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shinchi Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Fujiwara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Hosaka S; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Yamamoto Y; Department of Breast and Endocrine Surgery, Kumamoto University Hospital, Kumamoto, Japan.
Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; .; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4249-4258.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*pathology
Heparin-binding EGF-like Growth Factor/*genetics
Interleukin-6/*genetics
Macrophages/*cytology
Osteopontin/*genetics
Tumor-Associated Macrophages/*cytology
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Communication ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Female ; Heparin-binding EGF-like Growth Factor/metabolism ; Humans ; Interleukin-6/metabolism ; MCF-7 Cells ; Macrophages/metabolism ; Mice ; Neoplasm Transplantation ; Osteopontin/metabolism ; Tumor Microenvironment ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/pathology
Czasopismo naukowe
Tytuł :
Anti-inflammatory norclerodane diterpenoids and tetrahydrophenanthrene from the leaves and stems of Dioscorea bulbifera.
Autorzy :
Ngan NTT; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam. Electronic address: .
Hoang NH; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Truong VV; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Hien NT; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Lan NN; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Tung NV; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Huong PTM; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam.
Oh H; College of Pharmacy, Wonkwang University, Iksan 570-749, Republic of Korea.
Quang TH; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Viet Nam. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2021 Sep; Vol. 153, pp. 104965. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Dioscorea/*chemistry
Diterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents/isolation & purification ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Diterpenes/isolation & purification ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Mice ; Microglia/drug effects ; Molecular Structure ; Nitric Oxide ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Leaves/chemistry ; Plant Stems/chemistry ; Vietnam
Czasopismo naukowe
Tytuł :
RNA-binding protein SAMD4A inhibits breast tumor angiogenesis by modulating the balance of angiogenesis program.
Autorzy :
Zhou M; Department of Endocrinology, Beijing Jishuitan Hospital, The 4th Clinical Medical College of Peking University, Beijing, China.
Wang B; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Li H; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Han J; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Li A; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Lu W; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3835-3845. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*blood supply
Neovascularization, Pathologic/*genetics
Neovascularization, Pathologic/*metabolism
RNA-Binding Proteins/*metabolism
Repressor Proteins/*metabolism
Tumor Suppressor Proteins/*metabolism
Animals ; Disease Progression ; Female ; HEK293 Cells ; Humans ; MCF-7 Cells ; Mammary Glands, Human/cytology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transfection ; Tumor Burden/genetics ; Tumor Suppressor Proteins/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity.
Autorzy :
Weigelin B; Department of Cell Biology, RIMLS, Radboud University Medical Center, Nijmegen, The Netherlands. .; David H. Koch Center for Applied Research of Genitourinary Cancers, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .; Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University, Tübingen, Germany. .; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tuebingen, Tübingen, Germany. .
den Boer AT; Department of Internal Medicine, Maastricht University, Maastricht, The Netherlands.
Wagena E; Department of Cell Biology, RIMLS, Radboud University Medical Center, Nijmegen, The Netherlands.
Broen K; Department of Laboratory Medicine - Laboratory of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
Dolstra H; Department of Laboratory Medicine - Laboratory of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
de Boer RJ; Theoretical Biology and Bioinformatics, Utrecht University, Utrecht, The Netherlands.
Figdor CG; Department of Tumor Immunology, RIMLS, Radboud University Medical Centre, Nijmegen, The Netherlands.
Textor J; Department of Tumor Immunology, RIMLS, Radboud University Medical Centre, Nijmegen, The Netherlands.
Friedl P; Department of Cell Biology, RIMLS, Radboud University Medical Center, Nijmegen, The Netherlands. .; David H. Koch Center for Applied Research of Genitourinary Cancers, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .; Cancer Genomics Centre Netherlands (CGC.nl), Utrecht, The Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 01; Vol. 12 (1), pp. 5217. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytotoxicity, Immunologic*
Melanoma/*therapy
Perforin/*metabolism
T-Lymphocytes, Cytotoxic/*immunology
Animals ; Apoptosis/immunology ; Cell Death ; Cell Line, Tumor ; DNA Damage ; Female ; Humans ; Kinetics ; MCF-7 Cells ; Male ; Mice, Inbred C57BL ; Perforin/genetics
Czasopismo naukowe
Tytuł :
Thermoresponsive Pluronic based microgels for controlled release of curcumin against breast cancer cell line.
Autorzy :
Kulkarni AS; Department of Chemistry, Savitribai Phule Pune University, (Formerly, University of Pune), Pune, 411007, India.
Tapase SR; Department of Chemistry, Savitribai Phule Pune University, (Formerly, University of Pune), Pune, 411007, India.
Kodam KM; Department of Chemistry, Savitribai Phule Pune University, (Formerly, University of Pune), Pune, 411007, India.
Shinde VS; Department of Chemistry, Savitribai Phule Pune University, (Formerly, University of Pune), Pune, 411007, India. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Sep; Vol. 205, pp. 111834. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms*/drug therapy
Curcumin*/pharmacology
Microgels*
Delayed-Action Preparations ; Female ; Humans ; MCF-7 Cells ; Poloxamer
Czasopismo naukowe
Tytuł :
A Rational design of multi-functional nanoplatform: Fluorescent-based "off-on" theranostic gold nanoparticles modified with D-α-Tocopherol succinate.
Autorzy :
Demiral A; Research Institute for Health Science and Technologies (SABITA), 34810 Istanbul, Turkey; Graduate School of Health Sciences, Molecular Medicine and Biotechnology, Istanbul Medipol University, 34810 Istanbul, Turkey.
Verimli N; Research Institute for Health Science and Technologies (SABITA), 34810 Istanbul, Turkey; International School of Medicine, Medical Biochemistry, Istanbul Medipol University, 34810 Istanbul, Turkey.
Goralı Sİ; Research Institute for Health Science and Technologies (SABITA), 34810 Istanbul, Turkey; Graduate School of Health Sciences, Molecular Medicine and Biotechnology, Istanbul Medipol University, 34810 Istanbul, Turkey.
Yılmaz H; Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, Istanbul 34956, Turkey; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Ataşehir, Istanbul 34755, Turkey.
Çulha M; Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, Istanbul 34956, Turkey; Department of Internal Medicine, Morsani College of Medicine, The University of South Florida, Tampa, FL, United States of America; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Ataşehir, Istanbul 34755, Turkey.
Erdem SS; Research Institute for Health Science and Technologies (SABITA), 34810 Istanbul, Turkey; International School of Medicine, Medical Biochemistry, Istanbul Medipol University, 34810 Istanbul, Turkey. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2021 Sep; Vol. 222, pp. 112261. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Theranostic Nanomedicine*
Gold/*chemistry
Metal Nanoparticles/*chemistry
alpha-Tocopherol/*chemistry
Cell Survival/drug effects ; Humans ; MCF-7 Cells ; Metal Nanoparticles/toxicity ; Microscopy, Confocal ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/pharmacology ; Polyethylene Glycols/chemistry ; Quantum Theory ; Singlet Oxygen/metabolism ; Spectrometry, Fluorescence ; Verteporfin/chemistry ; Verteporfin/pharmacology
Czasopismo naukowe
Tytuł :
Novel quercetin encapsulated chitosan functionalized copper oxide nanoparticles as anti-breast cancer agent via regulating p53 in rat model.
Autorzy :
Elsayed AM; Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.
Sherif NM; Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.
Hassan NS; Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.
Althobaiti F; Department of Biotechnology, Collage of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia. Electronic address: .
Hanafy NAN; Nanomedicine group, Institute of Nanoscience and Nanotechnology, Kafrelsheikh University, 33516 Kafrelsheikh, Egypt. Electronic address: .
Sahyon HA; Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 31; Vol. 185, pp. 134-152. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Breast Neoplasms/*drug therapy
Chitosan/*chemistry
Copper/*chemistry
Quercetin/*administration & dosage
Tumor Suppressor Protein p53/*metabolism
9,10-Dimethyl-1,2-benzanthracene/adverse effects ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/chemically induced ; Breast Neoplasms/metabolism ; Caco-2 Cells ; Cell Cycle/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Compounding ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Metal Nanoparticles ; Proliferating Cell Nuclear Antigen/metabolism ; Quercetin/chemistry ; Quercetin/pharmacology ; Rats ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Colorimetric and fluorometric dual-readout protein kinase assay by tuning the active surface of nanoceria.
Autorzy :
Sun S; Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an 710119, Shaanxi, P. R. China. .
Zhang L
Lu X
Ren W
Liu C
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Aug 25; Vol. 57 (66), pp. 8154-8157. Date of Electronic Publication: 2021 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Colorimetry*
Fluorometry*
Cerium/*metabolism
Protein Kinases/*metabolism
Cerium/chemistry ; Humans ; MCF-7 Cells ; Protein Kinases/chemistry ; Surface Properties
Czasopismo naukowe
Tytuł :
Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer.
Autorzy :
Liu W; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.
Chakraborty B; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.
Safi R; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.
Kazmin D; Emory Vaccine Center, Emory University, Atlanta, GA, 30322, USA.
Chang CY; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.
McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 24; Vol. 12 (1), pp. 5103. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Homeostasis*
Lipid Metabolism*
Cholesterol/*metabolism
Ferroptosis/*physiology
Neoplasms/*metabolism
Animals ; Breast Neoplasms ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gene Expression Regulation, Neoplastic ; Glutathione Peroxidase/metabolism ; Humans ; Hydroxycholesterols ; Lung Neoplasms ; MCF-7 Cells ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasm Metastasis ; Neoplasms/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
An integrated high-throughput microfluidic circulatory fluorescence-activated cell sorting system (μ-CFACS) for the enrichment of rare cells.
Autorzy :
Cai K; Central Research Laboratories, Sysmex Corporation, 4-4-4 Takatsukadai, Nishi-ku, Kobe 651-2271, Japan. .
Mankar S; Central Research Laboratories, Sysmex Corporation, 4-4-4 Takatsukadai, Nishi-ku, Kobe 651-2271, Japan. .
Ajiri T; Central Research Laboratories, Sysmex Corporation, 4-4-4 Takatsukadai, Nishi-ku, Kobe 651-2271, Japan. .
Shirai K; Central Research Laboratories, Sysmex Corporation, 4-4-4 Takatsukadai, Nishi-ku, Kobe 651-2271, Japan. .
Yotoriyama T; Central Research Laboratories, Sysmex Corporation, 4-4-4 Takatsukadai, Nishi-ku, Kobe 651-2271, Japan. .
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Źródło :
Lab on a chip [Lab Chip] 2021 Aug 21; Vol. 21 (16), pp. 3112-3127. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article
MeSH Terms :
Microfluidic Analytical Techniques*
Microfluidics*
Cell Separation ; Flow Cytometry ; Humans ; Jurkat Cells ; MCF-7 Cells
Czasopismo naukowe

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