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Wyszukujesz frazę ""MESH: Antineoplastic Agents/pharmacology"" wg kryterium: Temat


Tytuł :
Multifaceted Study on a Cytochalasin Scaffold: Lessons on Reactivity, Multidentate Catalysis, and Anticancer Properties
Autorzy :
Gayraud, Oscar
Prévost, Sébastien
Sabbah, Michèle
Escargueil, Alexandre
Le Clainche, Christophe
Gautreau, Alexis
Blanchard, Florent
Frison, Gilles
Nay, Bastien
Zaghouani, Mehdi
Jactel, Vincent
Dezaire, Ambre
Lai, Thanh-Lan
Rocques, Nathalie
Romero, Stéphane
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Temat :
MESH: Stereoisomerism
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
MESH: Cytochalasins/chemistry
MESH: Crystallography, X-Ray
MESH: Palladium/chemistry
MESH: Thiourea/chemistry
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Organocatalysis
Density functional calculations
Natural products
MESH: Cytochalasins/pharmacology
[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
MESH: Copper/chemistry
MESH: Actin Cytoskeleton/drug effects
[SDV.CAN]Life Sciences [q-bio]/Cancer
[CHIM]Chemical Sciences
Medium-ring compounds
MESH: Hydrogen Bonding
MESH: Cell Survival/drug effects
MESH: Cycloaddition Reaction
[CHIM.ORGA]Chemical Sciences/Organic chemistry
MESH: Humans
MESH: Antineoplastic Agents/pharmacology
MESH: Antineoplastic Agents/chemistry
MESH: Catalysis
MESH: Thermodynamics
Antitumor agents
[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
MESH: Antineoplastic Agents/chemical synthesis
MESH: Cytochalasins/chemical synthesis
MESH: Molecular Conformation
[CHIM.CATA]Chemical Sciences/Catalysis
MESH: Cell Line, Tumor
Źródło :
Chemistry - A European Journal, Wiley-VCH Verlag, 2018, 24 (62), pp.16686-16691. ⟨10.1002/chem.201804023⟩
Chemistry - A European Journal, Wiley-VCH Verlag, 2018, 24 (62), pp.16686 - 16691. ⟨10.1002/chem.201804023⟩
Chemistry - A European Journal
Tytuł :
Evaluation of anti-diabetic and anti-tumoral activities of bioactive compounds from Phoenix dactylifera L’s leaf: In vitro and in vivo approach
Autorzy :
Chakroun, Mouna
Khemakhem, Bassem
Mabrouk, Hazem Ben
El Abed, Hanen
Makni, Mohamed
Bouaziz, Mohamed
Drira, Noureddine
Marrakchi, Naziha
Mejdoub, Hafedh
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Temat :
inhibitors
MESH: Animals
MESH: Phoeniceae/chemistry
[SDV.BV]Life Sciences [q-bio]/Vegetal Biology
MESH: Male
MESH: Polyphenols/therapeutic use
MESH: Diabetes Mellitus, Experimental/drug therapy
MESH: Plant Leaves/chemistry
LC–MS/MS analysis
MESH: Diabetes Mellitus, Experimental/complications
MESH: Phytochemicals/therapeutic use
MESH: Hypoglycemic Agents/therapeutic use
MESH: Plant Extracts/therapeutic use
MESH: alpha-Glucosidases/metabolism
Cytotoxic activity
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
IGR-39 cancer cell lines
MESH: Hypoglycemic Agents/pharmacology
MESH: Enzyme Assays
MESH: Plant Extracts/pharmacology
MESH: Hyperglycemia/complications
MESH: Diabetes Mellitus, Type 2/drug therapy
MESH: Hyperglycemia/drug therapy
MESH: Postprandial Period
MESH: Humans
Phoenix dactylifera L.’s leaves
MESH: Antineoplastic Agents/pharmacology
MESH: Tandem Mass Spectrometry
MESH: Diabetes Mellitus, Type 2/complications
MESH: Cell Death/drug effects
MESH: Phytochemicals/pharmacology
MESH: Chromatography, Liquid
MESH: Polyphenols/pharmacology
MESH: Mice
α-Glucosidase and α-Amylase
MESH: Antineoplastic Agents/therapeutic use
MESH: Phytotherapy
[SDV]Life Sciences [q-bio]
MESH: alpha-Amylases/metabolism
Antidiabetic activity
MESH: Cell Line, Tumor
Źródło :
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.415 - 422. ⟨10.1016/j.biopha.2016.09.062⟩
Biomedicine and Pharmacotherapy
Tytuł :
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
Autorzy :
Amiable, Claire
Paoletti, Julie
Haouz, Ahmed
Padilla, André
Labesse, Gilles
Kaminski, Pierre-Alexandre
Pochet, Sylvie
Pokaż więcej
Temat :
MESH: Drug Design
MESH : Enzyme Inhibitors/pharmacology
MESH : Antineoplastic Agents/metabolism
MESH : Enzyme Inhibitors/metabolism
MESH : Antineoplastic Agents/pharmacology
MESH : Proto-Oncogene Proteins/antagonists & inhibitors
MESH: Nuclear Proteins/metabolism
MESH : Animals
MESH : Nuclear Proteins/metabolism
MESH: Proto-Oncogene Proteins/chemistry
MESH: Nuclear Proteins/antagonists & inhibitors
MESH : Cell Line, Tumor
Inhibitor
[SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology
MESH: Nuclear Proteins/chemistry
MESH : Protein Conformation
MESH : Antineoplastic Agents/chemical synthesis
MESH: Proto-Oncogene Proteins/antagonists & inhibitors
MESH: Antineoplastic Agents/metabolism
MESH: N-Glycosyl Hydrolases/metabolism
MESH: Rats
MESH: Molecular Targeted Therapy
MESH : Molecular Docking Simulation
MESH : Proto-Oncogene Proteins/chemistry
MESH : Enzyme Inhibitors/chemical synthesis
MESH: N-Glycosyl Hydrolases/antagonists & inhibitors
MESH: Purine Nucleotides/chemical synthesis
MESH: Chemistry Techniques, Synthetic
MESH : Chemistry Techniques, Synthetic
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
MESH : Humans
MESH: Antineoplastic Agents/chemistry
MESH: Purine Nucleotides/pharmacology
MESH : Drug Screening Assays, Antitumor
MESH : Purine Nucleotides/pharmacology
MESH: Cell Line, Tumor
MESH: Molecular Docking Simulation
MESH: Animals
MESH : Antineoplastic Agents/chemistry
MESH : Nuclear Proteins/chemistry
MESH: Purine Nucleotides/chemistry
MESH: Enzyme Inhibitors/chemistry
MESH : Enzyme Inhibitors/chemistry
MESH : Proto-Oncogene Proteins/metabolism
Nucleoside analogues
MESH : Purine Nucleotides/metabolism
MESH : Purine Nucleotides/chemistry
MESH: Enzyme Inhibitors/chemical synthesis
DNPH1
MESH: Enzyme Inhibitors/metabolism
MESH: Protein Conformation
MESH : Drug Design
MESH: Proto-Oncogene Proteins/metabolism
Cross-coupling reaction
MESH: Enzyme Inhibitors/pharmacology
MESH : Purine Nucleotides/chemical synthesis
MESH: Humans
MESH: Purine Nucleotides/metabolism
MESH: Antineoplastic Agents/pharmacology
MESH : Molecular Targeted Therapy
MESH : N-Glycosyl Hydrolases/chemistry
MESH: N-Glycosyl Hydrolases/chemistry
MESH : Rats
MESH : N-Glycosyl Hydrolases/metabolism
MESH: Antineoplastic Agents/chemical synthesis
MESH : N-Glycosyl Hydrolases/antagonists & inhibitors
MESH: Drug Screening Assays, Antitumor
Crystal structure
Cancer
MESH: Structure-Activity Relationship
MESH : Nuclear Proteins/antagonists & inhibitors
MESH : Structure-Activity Relationship
Źródło :
European Journal of Medicinal Chemistry, Elsevier, 2014, 85, pp.418-37. ⟨10.1016/j.ejmech.2014.07.110⟩
European Journal of Medicinal Chemistry, Elsevier, 2014, 85, pp.418-37. 〈10.1016/j.ejmech.2014.07.110〉
European Journal of Medicinal Chemistry
Tytuł :
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
Autorzy :
Zakraoui, Ons
Marcinkiewicz, Cezary
Aloui, Zohra
Othman, Houcemeddine
Grépin, Renaud
Haoues, Meriam
Essafi, Makram
Srairi-Abid, Najet
Gasmi, Ammar
Karoui, Habib
Pagès, Gilles
Essafi-Benkhadir, Khadija
Pokaż więcej
Temat :
MESH: Animals
MESH: Reactive Oxygen Species/metabolism
MESH: Chickens
MESH: Colonic Neoplasms/pathology
MESH: Colon/pathology
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH: Viper Venoms/therapeutic use
MESH: Neovascularization, Pathologic/metabolism
disintegrin
tumor growth
MESH: Colonic Neoplasms/drug therapy
MESH: Neovascularization, Pathologic/drug therapy
MESH: Neovascularization, Pathologic/pathology
MESH: Colon/metabolism
colon cancer
MESH: Mice, Nude
MESH: Colon/drug effects
Lebein
MESH: Humans
MESH: Antineoplastic Agents/pharmacology
MESH: Apoptosis/drug effects
MESH: Viper Venoms/pharmacology
MESH: Integrin beta1/metabolism
MESH: Models, Molecular
cellular effectors
MESH: Down-Regulation/drug effects
MESH: Neovascularization, Pathologic/genetics
MESH: Cell Proliferation/drug effects
MESH: MAP Kinase Signaling System/drug effects
MESH: Antineoplastic Agents/therapeutic use
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
MESH: Vascular Endothelial Growth Factor A/metabolism
MESH: Colonic Neoplasms/genetics
MESH: Colonic Neoplasms/metabolism
MESH: Vascular Endothelial Growth Factor A/genetics
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
MESH: Cell Cycle Checkpoints/drug effects
MESH: Cell Line, Tumor
Źródło :
Molecular Carcinogenesis, Wiley, 2016, 56, pp.18-35. ⟨10.1002/mc.22470⟩
Tytuł :
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
Autorzy :
Amiable, Claire
Paoletti, Julie
Haouz, Ahmed
Padilla, André
Labesse, Gilles
Kaminski, Pierre Alexandre
Pochet, Sylvie
Pokaż więcej
Temat :
Cancer
Cross-coupling reaction
Crystal structure
DNPH1
Inhibitor
Nucleoside analogues
MESH: Animals
MESH: Antineoplastic Agents/chemical synthesis
MESH: Enzyme Inhibitors/chemistry
MESH: Enzyme Inhibitors/metabolism
MESH: Enzyme Inhibitors/pharmacology
MESH: Humans
MESH: Molecular Docking Simulation
MESH: Molecular Targeted Therapy
MESH: N-Glycosyl Hydrolases/antagonists & inhibitors
MESH: N-Glycosyl Hydrolases/chemistry
MESH: N-Glycosyl Hydrolases/metabolism
MESH: Nuclear Proteins/antagonists & inhibitors
MESH: Antineoplastic Agents/chemistry
MESH: Nuclear Proteins/chemistry
MESH: Nuclear Proteins/metabolism
MESH: Protein Conformation
MESH: Proto-Oncogene Proteins/antagonists & inhibitors
MESH: Proto-Oncogene Proteins/chemistry
MESH: Proto-Oncogene Proteins/metabolism
MESH: Purine Nucleotides/chemical synthesis
MESH: Purine Nucleotides/chemistry
MESH: Purine Nucleotides/metabolism
MESH: Purine Nucleotides/pharmacology
MESH: Antineoplastic Agents/metabolism
MESH: Rats
MESH: Structure-Activity Relationship
MESH: Antineoplastic Agents/pharmacology
MESH: Cell Line, Tumor
MESH: Chemistry Techniques, Synthetic
MESH: Drug Design
MESH: Drug Screening Assays, Antitumor
MESH: Enzyme Inhibitors/chemical synthesis
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Źródło :
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2014, 85, pp.418-37. ⟨10.1016/j.ejmech.2014.07.110⟩
Tytuł :
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
Autorzy :
Amiable, Claire
Paoletti, Julie
Haouz, Ahmed
Padilla, André
Labesse, Gilles
Kaminski, Pierre Alexandre
Pochet, Sylvie
Pokaż więcej
Temat :
Cancer
Cross-coupling reaction
Crystal structure
DNPH1
Inhibitor
Nucleoside analogues
MESH: Animals
MESH: Antineoplastic Agents/chemical synthesis
MESH: Enzyme Inhibitors/chemistry
MESH: Enzyme Inhibitors/metabolism
MESH: Enzyme Inhibitors/pharmacology
MESH: Humans
MESH: Molecular Docking Simulation
MESH: Molecular Targeted Therapy
MESH: N-Glycosyl Hydrolases/antagonists & inhibitors
MESH: N-Glycosyl Hydrolases/chemistry
MESH: N-Glycosyl Hydrolases/metabolism
MESH: Nuclear Proteins/antagonists & inhibitors
MESH: Antineoplastic Agents/chemistry
MESH: Nuclear Proteins/chemistry
MESH: Nuclear Proteins/metabolism
MESH: Protein Conformation
MESH: Proto-Oncogene Proteins/antagonists & inhibitors
MESH: Proto-Oncogene Proteins/chemistry
MESH: Proto-Oncogene Proteins/metabolism
MESH: Purine Nucleotides/chemical synthesis
MESH: Purine Nucleotides/chemistry
MESH: Purine Nucleotides/metabolism
MESH: Purine Nucleotides/pharmacology
MESH: Antineoplastic Agents/metabolism
MESH: Rats
MESH: Structure-Activity Relationship
MESH: Antineoplastic Agents/pharmacology
MESH: Cell Line, Tumor
MESH: Chemistry Techniques, Synthetic
MESH: Drug Design
MESH: Drug Screening Assays, Antitumor
MESH: Enzyme Inhibitors/chemical synthesis
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
Źródło :
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2014, 85, pp.418-37. ⟨10.1016/j.ejmech.2014.07.110⟩

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