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Tytuł :
Accumulation and Depuration of Cd and its Effect on the Expressions of Metallothionein and Apoptotic Genes in Litopenaeus vannamei.
Autorzy :
Li L; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China.
Shen YC; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China.
Liang JR; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China.
Liu H; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China.
Chen TC; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China.
Guo H; College of Fisheries, Guangdong Ocean University, Mazhang District, Haida Road No. 1, Zhanjiang, 524000, Guangdong, People's Republic of China. .; Guangdong Provincial Key Laboratory of Pathogenic Biology and Epidemiology for Aquatic Economic Animals & Key Laboratory of Control for Diseases of Aquatic Economic Animals of Guangdong Higher Education Institutes, Zhanjiang, China. .
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Źródło :
Bulletin of environmental contamination and toxicology [Bull Environ Contam Toxicol] 2021 Mar; Vol. 106 (3), pp. 501-506. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein*/genetics
Penaeidae*/genetics
Animals ; Cadmium/toxicity ; Gills ; Hepatopancreas
Czasopismo naukowe
Tytuł :
Synthetic fish metallothionein design as a potential tool for monitoring toxic metals in water.
Autorzy :
Nagamatsu PC; Laboratorio de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal do Paraná, Caixa postal 19031, Cep, Curitiba, PR, 81531-970, Brazil.
Vargas DÁR; Laboratorio de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal do Paraná, Caixa postal 19031, Cep, Curitiba, PR, 81531-970, Brazil.
Prodocimo MM; Laboratorio de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal do Paraná, Caixa postal 19031, Cep, Curitiba, PR, 81531-970, Brazil.
Opuskevitch I; Copel GeT-SOS/DNGT-Rua José Izidoro Biazetto, no. 18, Bloco A, CEP, Curitiba, PR, 81200-240, Brazil.
Ferreira FCAS; Copel GeT-SOS/DNGT-Rua José Izidoro Biazetto, no. 18, Bloco A, CEP, Curitiba, PR, 81200-240, Brazil.
Zanchin N; Instituto Carlos Chagas, Fiocruz-Pr, R. Prof. Algacyr Munhoz Mader 3775, Curitiba, PR, 81350-010, Brazil.
de Oliveira Ribeiro CA; Laboratorio de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal do Paraná, Caixa postal 19031, Cep, Curitiba, PR, 81531-970, Brazil.
de Souza C; Laboratorio de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal do Paraná, Caixa postal 19031, Cep, Curitiba, PR, 81531-970, Brazil. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Feb; Vol. 28 (8), pp. 9517-9528. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein*/genetics
Water Pollutants, Chemical*/analysis
Animals ; Brazil ; Ecosystem ; Environmental Monitoring ; Water
Czasopismo naukowe
Tytuł :
Expression profiles of metallothionein-I/II and megalin/LRP-2 in uterine cervical squamous lesions.
Autorzy :
Jakovac H; Department of Physiology and Immunology, Medical Faculty, University of Rijeka, B. Branchetta 20, 51 000, Rijeka, Croatia.
Stašić N; Teaching Institute of Public Health, Primorsko-goranska County, Medical Faculty, University of Rijeka, Rijeka, Croatia.
Krašević M; Department of Pathology, Medical Faculty, University of Rijeka, Rijeka, Croatia.
Jonjić N; Department of Pathology, Medical Faculty, University of Rijeka, Rijeka, Croatia.
Radošević-Stašić B; Department of Physiology and Immunology, Medical Faculty, University of Rijeka, B. Branchetta 20, 51 000, Rijeka, Croatia. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Apr; Vol. 478 (4), pp. 735-746. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*metabolism
Carcinoma, Squamous Cell/*metabolism
Cervical Intraepithelial Neoplasia/*metabolism
Low Density Lipoprotein Receptor-Related Protein-2/*metabolism
Metallothionein/*metabolism
Uterine Cervical Neoplasms/*metabolism
Biomarkers, Tumor/genetics ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cervical Intraepithelial Neoplasia/diagnosis ; Cervical Intraepithelial Neoplasia/genetics ; Cervical Intraepithelial Neoplasia/pathology ; Early Detection of Cancer ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Low Density Lipoprotein Receptor-Related Protein-2/genetics ; Metallothionein/genetics ; Transcriptome ; Tumor Microenvironment ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology
Czasopismo naukowe
Tytuł :
The N-Terminal Tail of Histone H3 Regulates Copper Homeostasis in Saccharomyces cerevisiae.
Autorzy :
Singh S; Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India.
Sahu RK; Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India.
Tomar RS; Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India .
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2021 Jan 25; Vol. 41 (2). Date of Electronic Publication: 2021 Jan 25 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Fungal*
Copper/*metabolism
DNA-Binding Proteins/*genetics
Histones/*genetics
Metallothionein/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Transcription Factors/*genetics
Amino Acid Sequence ; Copper/pharmacology ; DNA-Binding Proteins/metabolism ; Histone Acetyltransferases/genetics ; Histone Acetyltransferases/metabolism ; Histones/metabolism ; Homeostasis/genetics ; Metallothionein/metabolism ; Mutation ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Promoter Regions, Genetic ; Protein Binding ; Saccharomyces cerevisiae/drug effects ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Signal Transduction ; Stress, Physiological ; TATA-Box Binding Protein/genetics ; TATA-Box Binding Protein/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Effect of short-term dietary exposure on metal assimilation and metallothionein induction in the estuarine fish Pseudogobius sp.
Autorzy :
McDonald S; The School of BioSciences, The University of Melbourne, Parkville Campus, Parkville 3010, Victoria, Australia. Electronic address: .
Hassell K; The School of BioSciences, The University of Melbourne, Parkville Campus, Parkville 3010, Victoria, Australia; Aquatic Environmental Stress Research Group (AQUEST), School of Science, RMIT University, GPO Box 2476, Melbourne 3001, Victoria, Australia.
Cresswell T; ANSTO, Locked Bag 2001, Kirrawee 2232, New South Wales, Australia.
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Jun 10; Vol. 772, pp. 145042. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein*
Water Pollutants, Chemical*/toxicity
Animals ; Cadmium ; Dietary Exposure ; Ecosystem ; Metals
Czasopismo naukowe
Tytuł :
Metalation of a rice type 1 metallothionein isoform (OsMTI-1b).
Autorzy :
Malekzadeh R; Department of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, 88157-13471, Iran; Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: .
Shahpiri A; Department of Biotechnology, College of Agriculture, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Siapoush S; Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Science, Tabriz, 51664-15731, Iran.
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Źródło :
Protein expression and purification [Protein Expr Purif] 2020 Nov; Vol. 175, pp. 105719. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein*/biosynthesis
Metallothionein*/chemistry
Metallothionein*/genetics
Metallothionein*/isolation & purification
Plant Proteins*/biosynthesis
Plant Proteins*/chemistry
Plant Proteins*/genetics
Plant Proteins*/isolation & purification
Recombinant Fusion Proteins*/biosynthesis
Recombinant Fusion Proteins*/chemistry
Recombinant Fusion Proteins*/genetics
Recombinant Fusion Proteins*/isolation & purification
Cadmium/*chemistry
Copper/*chemistry
Oryza/*genetics
Zinc/*chemistry
Chromatography, Affinity ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Oryza/metabolism
Czasopismo naukowe
Tytuł :
Different responses in metallothionein gene expression and antioxidative enzyme activity lead to more ROS accumulation in rice exposed to Tl(III) than to Tl(I).
Autorzy :
Yao Y; School of Life Science, Key Laboratory for Functional Study on Plant Stress-Resistant Genes, Guangzhou University, Guangzhou, 510006, China. Electronic address: .
Wang M; School of Life Science, Key Laboratory for Functional Study on Plant Stress-Resistant Genes, Guangzhou University, Guangzhou, 510006, China.
Zhang P; School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou, 510006, China. Electronic address: .
Wang X; School of Life Science, Key Laboratory for Functional Study on Plant Stress-Resistant Genes, Guangzhou University, Guangzhou, 510006, China.
Huang X; School of Environmental Science and Engineering, Guangzhou University, Guangzhou, 510006, China.
Liu W; School of Environmental Science and Engineering, Guangzhou University, Guangzhou, 510006, China.
Wang Z; School of Life Science, Key Laboratory for Functional Study on Plant Stress-Resistant Genes, Guangzhou University, Guangzhou, 510006, China.
Yang R; School of Life Science, Key Laboratory for Functional Study on Plant Stress-Resistant Genes, Guangzhou University, Guangzhou, 510006, China.
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Źródło :
Chemosphere [Chemosphere] 2020 Nov; Vol. 259, pp. 127258. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein/*genetics
Oryza/*physiology
Reactive Oxygen Species/*metabolism
Thallium/*toxicity
Antioxidants/metabolism ; Catalase/metabolism ; Hydrogen Peroxide/metabolism ; Hydroponics ; Malondialdehyde/metabolism ; Metallothionein/metabolism ; Oryza/genetics ; Oryza/metabolism ; Peroxidase/metabolism ; Peroxidases/metabolism ; Plant Roots/metabolism ; Seedlings/metabolism ; Superoxide Dismutase/metabolism ; Superoxides/metabolism
Czasopismo naukowe
Tytuł :
Molecular Identification, Characterization, and Expression Analysis of a Metallothionein Gene from Septifer virgatus.
Autorzy :
Sakatoku A; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan. .
Ishikawa M; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
Yamazaki K; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
Nakamachi T; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
Kamachi H; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
Tanaka D; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
Nakamura S; Graduate School of Science and Engineering, Department of Environmental and Energy Science Faculty of Earth and Environmental Systems, University of Toyama, Toyama, 930-8555, Japan.
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Źródło :
Marine biotechnology (New York, N.Y.) [Mar Biotechnol (NY)] 2020 Aug; Vol. 22 (4), pp. 488-497. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Metallothionein/*genetics
Mytilidae/*genetics
Amino Acid Sequence ; Animals ; Cadmium Chloride/toxicity ; Chlorides/toxicity ; DNA, Complementary ; Environmental Biomarkers ; Metallothionein/chemistry ; Metallothionein/metabolism ; Mytilidae/drug effects ; Mytilidae/metabolism ; Water Pollution, Chemical ; Zinc Compounds/toxicity
Czasopismo naukowe
Tytuł :
CpG Site-Specific Regulation of Metallothionein-1 Gene Expression.
Autorzy :
Ogushi S; Department of Life Science, Faculty of Science and Engineering, Setsunan University, Neyagawa 572-8508, Japan.
Yoshida Y; Department of Pathological Biochemistry, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata 573-0101, Japan.
Nakanishi T; Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Kimura T; Department of Life Science, Faculty of Science and Engineering, Setsunan University, Neyagawa 572-8508, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 19; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Metallothionein/*genetics
Animals ; Cell Line, Tumor ; Cells, Cultured ; CpG Islands ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Metallothionein/metabolism ; Mice ; Mutation ; Promoter Regions, Genetic ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Metal- and Affinity-Specific Dual Labeling of Cysteine-Rich Proteins for Identification of Metal-Binding Sites.
Autorzy :
Peris-Díaz MD; Department of Chemical Biology, Faculty of Biotechnology, University of Wrocław, F. Joliot-Curie 14a, 50-383 Wrocław, Poland.
Guran R; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00 Brno, Czech Republic.
Zitka O; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00 Brno, Czech Republic.
Adam V; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.; Central European Institute of Technology, Brno University of Technology, Purkynova 123, 612 00 Brno, Czech Republic.
Krężel A; Department of Chemical Biology, Faculty of Biotechnology, University of Wrocław, F. Joliot-Curie 14a, 50-383 Wrocław, Poland.
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Źródło :
Analytical chemistry [Anal Chem] 2020 Oct 06; Vol. 92 (19), pp. 12950-12958. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metallothionein/*chemistry
Zinc/*analysis
Binding Sites ; Humans ; Hydrogen-Ion Concentration ; Metallothionein/genetics
Czasopismo naukowe
Tytuł :
Bioremediation potential of Cd by transgenic yeast expressing a metallothionein gene from Populus trichocarpa.
Autorzy :
De Oliveira VH; Department of Sustainable Land Management & Soil Research Centre, School of Agricultura, Policy and Development, University of Reading, RG6 6AR, UK.
Ullah I; School of Agriculture, Policy and Development, University of Reading, RG6 6AR, UK.
Dunwell JM; School of Agriculture, Policy and Development, University of Reading, RG6 6AR, UK.
Tibbett M; Department of Sustainable Land Management & Soil Research Centre, School of Agricultura, Policy and Development, University of Reading, RG6 6AR, UK. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Oct 01; Vol. 202, pp. 110917. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Biodegradation, Environmental*
Cadmium/*metabolism
Metallothionein/*genetics
Plant Proteins/*genetics
Populus/*genetics
Saccharomyces cerevisiae/*genetics
Soil Pollutants/*metabolism
Cadmium/toxicity ; Metallothionein/metabolism ; Metals, Heavy/analysis ; Populus/metabolism ; Saccharomyces cerevisiae/metabolism ; Soil
Czasopismo naukowe
Tytuł :
Interplay between Carbonic Anhydrases and Metallothioneins: Structural Control of Metalation.
Autorzy :
Wong DL; Department of Chemistry, The University of Western Ontario, 1151 Richmond St., London, ON N6A5B7, Canada.
Yuan AT; Department of Chemistry, The University of Western Ontario, 1151 Richmond St., London, ON N6A5B7, Canada.
Korkola NC; Department of Chemistry, The University of Western Ontario, 1151 Richmond St., London, ON N6A5B7, Canada.
Stillman MJ; Department of Chemistry, The University of Western Ontario, 1151 Richmond St., London, ON N6A5B7, Canada.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 09; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carbonic Anhydrases/*metabolism
Metalloproteins/*metabolism
Metallothionein/*metabolism
Metals/*metabolism
Animals ; Cadmium/chemistry ; Cadmium/metabolism ; Carbonic Anhydrases/chemistry ; Humans ; Metalloproteins/chemistry ; Metallothionein/chemistry ; Metals/chemistry ; Models, Molecular ; Protein Binding ; Protein Conformation ; Spectrometry, Mass, Electrospray Ionization ; Zinc/chemistry ; Zinc/metabolism
Czasopismo naukowe
Tytuł :
Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells.
Autorzy :
Wang K; Department of Pediatrics, Endocrinology and Metabolism, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.
Dai X; School of Bioscience and Technology, Chengdu Medical College, Chengdu, China.
He J; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.; Chinese-American Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Yan X; Chinese-American Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Yang C; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.
Fan X; Chinese-American Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Sun S; Chinese-American Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Chen J; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.
Xu J; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.
Deng Z; Department of Medicine, School of Medicine, University of Louisville, Louisville, KY.
Fan J; School of Bioscience and Technology, Chengdu Medical College, Chengdu, China.
Yuan X; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.; Heilongjiang Key Laboratory of Tissue Damage and Repair, Mudanjiang Medical University, Heilongjiang, China.
Liu H; Experimental Research Center, the First Affiliated Hospital, Chengdu Medical College, Chengdu, Sichuan, China.
Carlson EC; Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND.
Shen F; Department of Pediatrics, Endocrinology and Metabolism, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wintergerst KA; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.; Division of Endocrinology, Department of Pediatrics, University of Louisville, Norton Children's Medical Group, Louisville, KY.; Wendy Novak Diabetes Center, Louisville, KY.
Conklin DJ; Department of Medicine, School of Medicine, University of Louisville, Louisville, KY.; Diabetes and Obesity Center, University of Louisville, Louisville, KY.
Epstein PN; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY.; Wendy Novak Diabetes Center, Louisville, KY.
Lu C; Department of Pediatrics, Endocrinology and Metabolism, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tan Y; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY .; Wendy Novak Diabetes Center, Louisville, KY.
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Źródło :
Diabetes [Diabetes] 2020 Aug; Vol. 69 (8), pp. 1779-1792. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CXCL12/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Diabetes Mellitus, Experimental/*prevention & control
Endothelial Progenitor Cells/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Metallothionein/*metabolism
Neovascularization, Pathologic/*metabolism
Neovascularization, Pathologic/*prevention & control
Animals ; Blotting, Western ; Cell Survival/genetics ; Cell Survival/physiology ; Chemokine CXCL12/genetics ; Enzyme-Linked Immunosorbent Assay ; Female ; Hindlimb/pathology ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Ischemia/genetics ; Ischemia/metabolism ; Leukocytes, Mononuclear/metabolism ; Male ; Metallothionein/genetics ; Mice ; Oxidative Stress/genetics ; Oxidative Stress/physiology ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Zinc protects against cadmium-induced toxicity in neonatal murine engineered cardiac tissues via metallothionein-dependent and independent mechanisms.
Autorzy :
Yu HT; The Pediatric Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, 40292, USA.; The First Hospital of Jilin University, Changchun, 130021, China.
Zhen J; The Pediatric Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, 40292, USA.; The First Hospital of Jilin University, Changchun, 130021, China.
Xu JX; The Pediatric Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, 40292, USA.
Cai L; The Pediatric Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, 40292, USA.; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, 40202, USA.; Department of Radiation Oncology, The University of Louisville School of Medicine, Louisville, KY, USA.
Leng JY; The First Hospital of Jilin University, Changchun, 130021, China.
Ji HL; The First Hospital of Jilin University, Changchun, 130021, China. .
Keller BB; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, 40202, USA. .; Kosair Charities Pediatric Heart Research Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, 40202, USA. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 May; Vol. 41 (5), pp. 638-649. Date of Electronic Publication: 2019 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Tissue Engineering*
Cadmium/*toxicity
Metallothionein/*metabolism
Myocytes, Cardiac/*drug effects
Zinc/*pharmacology
Animals ; Cadmium/administration & dosage ; Dose-Response Relationship, Drug ; Metallothionein/deficiency ; Metallothionein/genetics ; Mice ; Mice, Knockout ; Myocytes, Cardiac/metabolism
Czasopismo naukowe
Tytuł :
Cigarette Smoking during Pregnancy: Effects on Antioxidant Enzymes, Metallothionein and Trace Elements in Mother-Newborn Pairs.
Autorzy :
Pizent A; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Lazarus M; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Kovačić J; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Tariba Lovaković B; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Brčić Karačonji I; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Živković Semren T; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Sekovanić A; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Orct T; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Branović-Čakanić K; Croatian Veterinary Institute, 10000 Zagreb, Croatia.
Brajenović N; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Jurič A; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Miškulin I; University Hospital Centre, 10000 Zagreb, Croatia.
Škrgatić L; University Hospital Centre, 10000 Zagreb, Croatia.
Stasenko S; Merkur University Hospital, 10000 Zagreb, Croatia.
Mioč T; Merkur University Hospital, 10000 Zagreb, Croatia.
Jurasović J; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Piasek M; Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
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Źródło :
Biomolecules [Biomolecules] 2020 Jun 10; Vol. 10 (6). Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*metabolism
Cigarette Smoking/*adverse effects
Cigarette Smoking/*metabolism
Metallothionein/*blood
Trace Elements/*blood
Adult ; Cotinine/urine ; Discriminant Analysis ; Female ; Humans ; Infant, Newborn ; Metallothionein/urine ; Mothers ; Non-Smokers ; Pregnancy ; Smokers ; Trace Elements/urine
Czasopismo naukowe
Tytuł :
Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess.
Autorzy :
Gudekar N; The Genetics Area Program, University of Missouri, Columbia, MO, 65211, USA.; The Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Shanbhag V; The Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.; The Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA.
Wang Y; The Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.; The Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO, 65211, USA.; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, People's Republic of China.
Ralle M; The Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, 97239, USA.
Weisman GA; The Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.; The Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA.
Petris MJ; The Genetics Area Program, University of Missouri, Columbia, MO, 65211, USA. .; The Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA. .; The Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA. .; The Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO, 65211, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 May 12; Vol. 10 (1), pp. 7856. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Copper/*pharmacology
Copper-Transporting ATPases/*metabolism
Metallothionein/*metabolism
Animals ; Cell Line ; Cell Survival/drug effects ; Copper-Transporting ATPases/deficiency ; Copper-Transporting ATPases/genetics ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Golgi Apparatus/drug effects ; Golgi Apparatus/metabolism ; Metallothionein/deficiency ; Metallothionein/genetics ; Mice ; Mutation ; Protein Transport/drug effects
Czasopismo naukowe
Tytuł :
Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
Autorzy :
Pretsch D; Oxford Antibiotic Group GmbH, Konrad-Lorenz-Straße 24, 3430, Tulln, Austria. .
Rollinger JM; Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Schmid A; Department of Neuroscience and Developmental Biology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Genov M; Oxford Antibiotic Group GmbH, Konrad-Lorenz-Straße 24, 3430, Tulln, Austria.
Wöhrer T; Oxford Antibiotic Group GmbH, Konrad-Lorenz-Straße 24, 3430, Tulln, Austria.
Krenn L; Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Moloney M; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
Kasture A; Department of Neuroscience and Developmental Biology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Hummel T; Department of Neuroscience and Developmental Biology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Pretsch A; Oxford Antibiotic Group GmbH, Konrad-Lorenz-Straße 24, 3430, Tulln, Austria.
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 16; Vol. 10 (1), pp. 11707. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging/*metabolism
Amyloid beta-Peptides/*metabolism
Caenorhabditis elegans/*metabolism
Caenorhabditis elegans Proteins/*metabolism
Metallothionein/*metabolism
alpha-Synuclein/*metabolism
Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Animals ; Animals, Genetically Modified ; Benzothiazoles/administration & dosage ; Benzothiazoles/pharmacology ; Clioquinol/administration & dosage ; Clioquinol/pharmacology ; Disease Models, Animal ; Emodin/administration & dosage ; Emodin/pharmacology ; Gene Knockdown Techniques ; Homeostasis/drug effects ; Metallothionein/genetics ; Metals/metabolism ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/pharmacology ; Parkinson Disease/drug therapy ; Parkinson Disease/metabolism ; Quercetin/administration & dosage ; Quercetin/pharmacology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Ag Ion Binding to Human Metallothionein-2A Is Cooperative and Domain Specific.
Autorzy :
Dong S; Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Shirzadeh M; Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Fan L; Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Laganowsky A; Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Russell DH; Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
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Źródło :
Analytical chemistry [Anal Chem] 2020 Jul 07; Vol. 92 (13), pp. 8923-8932. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Metallothionein/*metabolism
Silver/*metabolism
Spectrometry, Mass, Electrospray Ionization/*methods
Binding Sites ; Cadmium/chemistry ; Cadmium/metabolism ; Ethylmaleimide/chemistry ; Humans ; Ion Mobility Spectrometry ; Ions/chemistry ; Metallothionein/chemistry ; Protein Binding ; Protein Domains ; Silver/chemistry
Czasopismo naukowe
Tytuł :
The association of blood lead levels and renal effects may be modified by genetic combinations of Metallothionein 1A 2A polymorphisms.
Autorzy :
Yang CC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Occupational and Environmental Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.; Department of Family Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.; Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Lin CI; Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Health Management Center, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
Lee SS; Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Wang CL; Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Dai CY; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chuang HY; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. .; Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 15; Vol. 10 (1), pp. 9603. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney/*drug effects
Lead/*blood
Lead Poisoning/*genetics
Metallothionein/*genetics
Polymorphism, Single Nucleotide/*genetics
Acetylglucosaminidase/urine ; Adult ; Biomarkers/urine ; Female ; Humans ; Male ; Metallothionein/metabolism ; Middle Aged ; Uric Acid/urine
Czasopismo naukowe
Tytuł :
Genetic Engineering-Facilitated Coassembly of Synthetic Bacterial Cells and Magnetic Nanoparticles for Efficient Heavy Metal Removal.
Autorzy :
Zhu N; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, P. R. China.
Zhang B; College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Yu Q; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, P. R. China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 May 20; Vol. 12 (20), pp. 22948-22957. Date of Electronic Publication: 2020 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cadmium/*isolation & purification
Lead/*isolation & purification
Magnetic Iron Oxide Nanoparticles/*chemistry
Metallothionein/*chemistry
Water Pollutants, Chemical/*isolation & purification
Amino Acid Sequence ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Genetic Engineering ; Green Fluorescent Proteins/genetics ; Humans ; Magnetic Phenomena ; Metallothionein/genetics ; Pentetic Acid/chemistry ; Polyethyleneimine/chemistry ; Pseudomonas putida/genetics ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Silicon Dioxide/chemistry
Czasopismo naukowe

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