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Tytuł:
COSAP: Comparative Sequencing Analysis Platform.
Autorzy:
Ergun MA; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Cinal O; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Bakışlı B; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Emül AA; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Baysan M; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Mar 26; Vol. 25 (1), pp. 130. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Copy Number Variations*
Microsatellite Instability*
Humans ; Reproducibility of Results ; High-Throughput Nucleotide Sequencing/methods ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
Autorzy:
Deycmar S; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Roche Postdoctoral Fellowship (RPF) Program, Basel, Switzerland.
Johnson BJ; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Ray K; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Schaaf GW; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Ryan DP; School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Cullin C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Dozier BL; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Ferguson B; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Bimber BN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Olson JD; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Caudell DL; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Whitlow CT; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Solingapuram Sai KK; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Romero EC; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA.
Villinger FJ; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA.
Burgos AG; Caribbean Primate Research Center, University of Puerto Rico, Toa Baja, PR, USA.
Ainsworth HC; Department of Biostatistics and Data Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Miller LD; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Hawkins GA; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Chou JW; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Gomes B; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Hettich M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Ceppi M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; iTeos Therapeutics, Translational Medicine, Gosselies, Belgium.
Charo J; Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland.
Cline JM; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 19; Vol. 22 (1), pp. 292. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/pathology
Brain Neoplasms*
Neoplastic Syndromes, Hereditary*
Humans ; Animals ; Macaca mulatta/genetics ; Macaca mulatta/metabolism ; MutL Protein Homolog 1/genetics ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; DNA Methylation/genetics ; Epigenesis, Genetic ; Transcription Factors/genetics ; Transcription Factors/metabolism ; DNA/metabolism ; DNA Mismatch Repair/genetics
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An association between ATP7B expression and human cancer prognosis and immunotherapy: a pan-cancer perspective.
Autorzy:
Zhang Z; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Zhang A; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Shi Y; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Zhao Z; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, No. 50, a pine in Xiangshan, Haidian District, Beijing, China.
Zhao Z; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China. .; Department of Neurosurgery, The Fourth Hospital of Hebei Medical University, No. 12 Jiankang Road, Chang'an District, Shijiazhuang, Hebei Province, China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Nov 30; Vol. 16 (1), pp. 307. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Neoplasms*/genetics
Neoplasms*/therapy
Humans ; Immunotherapy ; Adjuvants, Immunologic ; Databases, Factual ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic profile of Chinese patients with small bowel cancer categorized by anatomic location.
Autorzy:
Shi C; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Ma J; School of Nursing, Yunnan University of Traditional Chinese Medicines, Kunming, Yunnan, 650504, P.R. China.
Zhang T; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Shi Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Duan W; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China.
Huang D; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China.
Zhang H; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China. .; Zhaotong Health Vocational College, Zhaotong, Yunnan, 657000, P.R. China. .
Zeng Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Nov 16; Vol. 16 (1), pp. 289. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/genetics
Humans ; East Asian People ; Genetic Profile ; Mutation ; Biomarkers, Tumor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of RNF150 as the hub gene associated with microsatellite instability in gastric cancer.
Autorzy:
Pan J; Department of Gastroenterology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Lan Q; Department of Pathology, Renmin Hospital, Wuhan University, Wuhan, 430060, Hubei, China.
Li S; Department of Gastroenterology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 01; Vol. 13 (1), pp. 12495. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Stomach Neoplasms*/pathology
Humans ; Microsatellite Repeats/genetics ; Membrane Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy.
Autorzy:
Zheng X; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Lin J; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Xiong J; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Guan Y; Geneplus-Beijing Institute, Beijing, China.
Lan B; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Li Y; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Gao X; Geneplus-Beijing Institute, Beijing, China.
Fei Z; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen L; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Chen G; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Department of Pathology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Guo Z; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Yi X; Geneplus-Beijing Institute, Beijing, China.
Cao W; Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ai X; Department of Shanghai Lung Cancer Center, Shanghai Jiao Tong University Affiliated Chest Hospital, Shanghai, China.
Zhou C; First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Li X; Department of Oncology, Affiliated Quanzhou First Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.
Zhao J; Department of Thoracic Oncology, Peking University Cancer Hospital & Institute, Beijing, China.
Yan X; Department of Internal Medicine, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan Province, Zhengzhou, China.
Yu Q; Department of Oncology, The Cancer Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi Zhuang Autonomous Region, China.
Si L; Department of Renal Cancer and Melanoma, Peking University Cancer Hospital and Institute, Beijing, China.
Chen Y; Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .
Chen C; Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .; Cancer Bio-Immunotherapy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Jul 21; Vol. 23 (1), pp. 686. Date of Electronic Publication: 2023 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*/genetics
Microsatellite Instability*
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/mortality
Humans ; Asian People ; Cohort Studies ; DNA Mismatch Repair/genetics ; Genomic Instability ; Immunotherapy ; Mutation ; Recombinational DNA Repair/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of heavy metals in the development of colorectal cancer.
Autorzy:
Li Y; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Lou J; Shanghai Biotecan Pharmaceuticals Co., Ltd, Shanghai, 201204, China.
Hong S; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Hou D; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Lv Y; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Guo Z; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Wang K; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China.
Xu Y; Shanghai Biotecan Pharmaceuticals Co., Ltd, Shanghai, 201204, China.
Zhai Y; Shanghai Biotecan Pharmaceuticals Co., Ltd, Shanghai, 201204, China. .
Liu H; Department of Colorectal Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, 046000, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Jul 03; Vol. 23 (1), pp. 616. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/blood
Colorectal Neoplasms*/epidemiology
Colorectal Neoplasms*/genetics
Metals, Heavy*/blood
DNA-Binding Proteins*/genetics
Endonucleases*/genetics
X-ray Repair Cross Complementing Protein 1*
Proto-Oncogene Proteins B-raf*/genetics
Microsatellite Instability*
Polymorphism, Genetic ; Risk Factors ; Humans ; Male ; Female ; Adult ; Middle Aged ; Incidence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series.
Autorzy:
Nádorvári ML; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Kenessey I; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Kiss A; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Barbai T; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Kulka J; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Rásó E; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Tímár J; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 13; Vol. 22 (1), pp. 150. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/pathology
Neoplastic Syndromes, Hereditary*/genetics
Brain Neoplasms*/genetics
Humans ; Microsatellite Instability ; DNA Mismatch Repair/genetics
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Helicobacter pylori and Epstein-Barr Virus Co-Infection in Gastric Disease: What Is the Correlation with p53 Mutation , Genes Methylation and Microsatellite Instability in a Cohort of Sicilian Population?
Autorzy:
Giammanco A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Anzalone R; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Serra N; Department of Public Health, University Federico II of Naples, 80138 Napoli, Italy.
Graceffa G; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Vieni S; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Scibetta N; Anatomopathology Unit, Arnas Civico Di Cristina Benfratelli Hospital, 90127 Palermo, Italy.
Rea T; Public Health Department, Federico II University Hospital, 80131 Naples, Italy.
Capra G; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Fasciana T; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 30; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Helicobacter Infections*/complications
Epstein-Barr Virus Infections*/complications
Stomach Diseases*/genetics
Stomach Diseases*/microbiology
Stomach Diseases*/virology
Genes, p53*/genetics
DNA Methylation*
Microsatellite Instability*
Helicobacter pylori ; Herpesvirus 4, Human ; Coinfection ; Mutation ; Sicily ; Humans ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Logistic Models
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Autorzy:
Wu T; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Zhang X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Liu X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Cai X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Shen T; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Pan D; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Liang R; College of Bioengineering, Chongqing University, Chongqing, China.
Ding R; Department of Minimally Invasive Intervention, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Hu R; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Dong J; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Li F; Department of Gastroenteroscopy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Li J; Department of Gastroenteroscopy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Xie L; Department of Oncology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Wang C; Department of Radiology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Geng S; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Yang Z; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Xing L; Department of Dermatology, Kunming Children's Hospital, Kunming, China. .
Li Y; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China. .
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Źródło:
BMC medicine [BMC Med] 2023 Apr 27; Vol. 21 (1), pp. 161. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Animals ; Mice ; CD8-Positive T-Lymphocytes/pathology ; Immunohistochemistry ; Tumor Microenvironment
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
Autorzy:
Geurts BS; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Battaglia TW; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van Berge Henegouwen JM; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Zeverijn LJ; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
de Wit GF; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Hoes LR; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van der Wijngaart H; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
van der Noort V; Department of Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Roepman P; Hartwig Medical Foundation, Amsterdam, the Netherlands.
de Leng WWJ; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Jansen AML; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Opdam FL; Department of Clinical Pharmacology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.
de Jonge MJA; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Cirkel GA; Department of Medical Oncology, Meander, Amersfoort, the Netherlands.
Labots M; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
Hoeben A; Department of Medical Oncology, Department of Internal Medicine, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Kerver ED; Department of Medical Oncology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Bins AD; Department of Medical Oncology, Amsterdam University Medical Centre, location AUMC, Amsterdam, the Netherlands.
Erdkamp FGL; Department of Medical Oncology, Zuyderland Hospital, Sittard-Geelen, the Netherlands.
van Rooijen JM; Department of Medical Oncology, Martini Hospital, Groningen, the Netherlands.
Houtsma D; Department of Medical Oncology, Haga Hospital, The Hague, the Netherlands.
Hendriks MP; Department of Medical Oncology, Northwest Clinics, Alkmaar, the Netherlands.
de Groot JB; Department of Medical Oncology, Isala, Zwolle, the Netherlands.
Verheul HMW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Gelderblom H; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Voest EE; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. .; Oncode Institute, Utrecht, the Netherlands. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Mar 04; Vol. 23 (1), pp. 205. Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Brain Neoplasms*
Humans ; Biomarkers
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.
Autorzy:
Martianov AS; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Department of Medical Genetics, St.-Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
Mitiushkina NV; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Ershova AN; Department of Medical Genetics, St.-Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
Martynenko DE; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Bubnov MG; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Amankwah P; Department of Medical Genetics, St.-Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
Yanus GA; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Department of Medical Genetics, St.-Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
Aleksakhina SN; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Tiurin VI; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Venina AR; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Anuskina AA; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Gorgul YA; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Shestakova AD; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Maidin MA; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Belyaev AM; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Baboshkina LS; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Iyevleva AG; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Imyanitov EN; Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Department of Medical Genetics, St.-Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/pathology
Humans ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; Mutation ; Codon ; Membrane Proteins/genetics ; GTP Phosphohydrolases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer.
Autorzy:
Streel S; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Salmon A; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Dheur A; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Bours V; Department of Human Genetics, CHU Liège, 4000 Liège, Belgium.
Leroi N; Department of Human Genetics, CHU Liège, 4000 Liège, Belgium.
Habran L; Department of Pathology, CHU Liège, 4000 Liège, Belgium.
Delbecque K; Department of Pathology, CHU Liège, 4000 Liège, Belgium.
Goffin F; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Pleyers C; Department of Radiotherapy Oncology, CHU Liège, 4000 Liège, Belgium.
Kakkos A; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Gonne E; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Seidel L; Department of Biostatistics, CHU Liège, 4000 Liège, Belgium.
Kridelka F; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Gennigens C; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Endometrial Neoplasms*/genetics
Female ; Humans ; Tumor Suppressor Protein p53/genetics ; Immunohistochemistry ; Mutation ; DNA Mismatch Repair
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DeltaMSI: artificial intelligence-based modeling of microsatellite instability scoring on next-generation sequencing data.
Autorzy:
Swaerts K; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium.; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
Dedeurwaerdere F; Department of Pathology, AZ Delta General Hospital, Roeselare, Belgium.
De Smet D; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium.; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
De Jaeger P; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
Martens GA; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium. .; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium. .; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Mar 01; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2023 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Artificial Intelligence*
Humans ; Microsatellite Repeats ; High-Throughput Nucleotide Sequencing ; Machine Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment of a gastric cancer cell line with high microsatellite instability, OCUM-13, derived from Borrmann type-2 primary tumor.
Autorzy:
Yamamoto Y; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Masuda G; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Kushiyama S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Maruo K; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Tsujio G; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Sera T; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Sugimoto A; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Nishimura S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Kuroda K; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Togano S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Okuno T; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Ohira M; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Yashiro M; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Mar; Vol. 12 (5), pp. 6016-6022. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Stomach Neoplasms*/pathology
Animals ; Mice ; Microsatellite Repeats ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pan-cancer analysis of the prognostic and immunological role of SNX29: a potential target for survival and immunotherapy.
Autorzy:
Xu C; Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.; School of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People's Republic of China.; First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.
Li F; Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.; School of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People's Republic of China.
Liu Z; Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.; School of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People's Republic of China.; First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.
Yan C; Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China. .; School of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People's Republic of China. .; First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China. .
Xiao J; Department of Gastrointestinal Surgery, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China. .; School of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People's Republic of China. .; First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Feb 24; Vol. 16 (1), pp. 34. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Neoplasms*
Humans ; Prognosis ; Genes, Regulator ; Transcription Factors ; Immunotherapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Autorzy:
Zhang W; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Chen L; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Liu J; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Chen B; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Shi H; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Chen H; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Qi H; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Wu Z; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Mao X; Department of Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Wang X; Department of Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Huang Y; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Li J; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Yu Z; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China.
Zhong M; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China. mkzhong_.
Wang T; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China. .
Li Q; Department of Pharmacy, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai, 200040, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Apr 16; Vol. 43 (1), pp. 114. Date of Electronic Publication: 2024 Apr 16.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Brain Neoplasms*
Neoplastic Syndromes, Hereditary*
Humans ; Microsatellite Instability ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Autophagy-Related Protein 7/genetics ; Immunity ; Cholesterol ; DNA Mismatch Repair
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study.
Autorzy:
Zhan PC; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Yang S; Department of Radiology, The Second Hospital, Cheello College of Medicine, Shandong University, 250033, Jinan, PR China.
Liu X; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Zhang YY; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, Henan, PR China.
Wang R; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Wang JX; Department of Interventional Medicine, The Second Hospital, Cheello College of Medicine, Shandong University, 250033, Jinan, Shandong, PR China.
Qiu QY; Zhengzhou University Medical College, 450052, Zhengzhou, Henan, PR China.
Gao Y; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Lv DB; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Li LM; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Luo CL; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Hu ZW; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Li Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, Henan, PR China.
Lyu PJ; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Liang P; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China.
Gao JB; Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe Road, 450052, Zhengzhou, Henan, PR China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Apr 01; Vol. 24 (1), pp. 404. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Radiomics*
Stomach Neoplasms*/diagnostic imaging
Stomach Neoplasms*/genetics
Stomach Neoplasms*/therapy
Humans ; Cohort Studies ; Retrospective Studies ; Microsatellite Instability ; Immunotherapy ; Tomography, X-Ray Computed ; Immunoglobulins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association between colorectal cancer, the frequency of Bacteroides fragilis, and the level of mismatch repair genes expression in the biopsy samples of Iranian patients.
Autorzy:
Nazarinejad N; Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Hajikhani B; Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Vaezi AA; Department of Internal Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Firoozeh F; Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Sameni F; Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran.
Yaslianifard S; Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Goudarzi M; Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dadashi M; Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran. m_.; Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran. m_.
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2024 Feb 23; Vol. 24 (1), pp. 82. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/pathology
Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics
Colorectal Neoplasms, Hereditary Nonpolyposis*/pathology
Humans ; DNA Mismatch Repair/genetics ; Bacteroides fragilis/genetics ; Bacteroides fragilis/metabolism ; Iran ; MutS Homolog 2 Protein/genetics ; MutS Homolog 2 Protein/metabolism ; Microsatellite Instability ; DNA-Binding Proteins/genetics ; MutL Protein Homolog 1/genetics ; MutL Protein Homolog 1/metabolism ; Biopsy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel immune-related gene signature for diagnosis and potential immunotherapy of microsatellite stable endometrial carcinoma.
Autorzy:
Xiao Y; Department of Gynecology and Obstetrics, Dalian Maternal and Children's Medical Group, No. 1 Dunhuang Street, Shahekou District, Dalian, 116033, Liaoning, China.
Yu X; Department of Gynecology and Obstetrics, Dalian Maternal and Children's Medical Group, No. 1 Dunhuang Street, Shahekou District, Dalian, 116033, Liaoning, China.
Wang Y; Department of Pathology, Dalian Maternal and Children's Medical Group, Dalian, 116033, Liaoning, China.
Song G; Department of Pathology, Dalian Maternal and Children's Medical Group, Dalian, 116033, Liaoning, China.
Liu M; Department of Pathology, Dalian Maternal and Children's Medical Group, Dalian, 116033, Liaoning, China.
Wang D; Department of Oncology, Dalian Maternal and Children's Medical Group, No. 1 Dunhuang Street, Shahekou District, Dalian, 116033, Liaoning, China. .
Wang H; Department of Gynecology and Obstetrics, Dalian Maternal and Children's Medical Group, No. 1 Dunhuang Street, Shahekou District, Dalian, 116033, Liaoning, China. wanghl_.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 14; Vol. 14 (1), pp. 3738. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Oncogenes*
Endometrial Neoplasms*/diagnosis
Endometrial Neoplasms*/genetics
Endometrial Neoplasms*/therapy
Humans ; Female ; Aged ; Risk Factors ; Immunotherapy ; Microsatellite Instability ; Microsatellite Repeats/genetics ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Short tandem repeat mutations regulate gene expression in colorectal cancer.
Autorzy:
Verbiest MA; Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland. .; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland. .; Swiss Institute of Bioinformatics, Lausanne, Switzerland. .
Lundström O; Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland.; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Xia F; Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland.; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Baudis M; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Bilgin Sonay T; Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Ecology, Evolution and Environmental Biology, Columbia University, New York, USA.
Anisimova M; Institute of Computational Life Sciences, Zurich University of Applied Sciences, Wädenswil, Switzerland. .; Swiss Institute of Bioinformatics, Lausanne, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3331. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Repeats*/genetics
Colorectal Neoplasms*/pathology
Humans ; Mutation ; Microsatellite Instability ; Gene Expression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A pan-cancer analysis uncovering the function of CRHBP in tumor immunity, prognosis and drug response: especially its function in LIHC.
Autorzy:
Chen B; Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Chen S; Department of General Surgery, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Wang X; Department of Radiation Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhang J; Department of Emergency Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wang H; Department of Operation Theater, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Li J; The Second Clinical Medical College of Anhui Medical University, Hefei, China.
Zhang Z; The First Clinical Medical College of Anhui Medical University, Hefei, China.
Yu F; Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China. .
Kong W; Department of Emergency Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China. .; Gastrointestinal Surgery Department, West China Hospital of Sichuan University, Chengdu, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3112. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Humans ; Microsatellite Instability ; Prognosis ; Databases, Protein ; Tumor Microenvironment/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Construction and validation of a colon cancer prognostic model based on tumor mutation burden-related genes.
Autorzy:
Zou D; The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Xu T; The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 04; Vol. 14 (1), pp. 2867. Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/diagnosis
Colonic Neoplasms*/genetics
Colonic Neoplasms*/therapy
Humans ; Prognosis ; Immunotherapy ; Computational Biology ; Microsatellite Instability ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma.
Autorzy:
Huang W; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ho CL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lee CT; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen WL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Yang SC; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Chow NH; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen YL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
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Źródło:
PloS one [PLoS One] 2023 Apr 25; Vol. 18 (4), pp. e0284227. Date of Electronic Publication: 2023 Apr 25 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Humans ; DNA Mismatch Repair/genetics ; Workflow ; Microsatellite Repeats/genetics ; DNA-Binding Proteins/genetics ; Electrophoresis, Capillary ; MutL Protein Homolog 1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development and Interpretation of a Clinicopathological-Based Model for the Identification of Microsatellite Instability in Colorectal Cancer.
Autorzy:
Jiang Z; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Yan L; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Deng S; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Gu J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Qin L; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.; Department of General Surgery, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, Xinjiang 832008, China.
Mao F; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Xue Y; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Cai W; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Nie X; Department of Pathology, Union Hospital, Tongji Medical, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Liu H; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Shang F; Department of Medical Oncology, Nanyang Central Hospital, Nanyang, Henan, China.
Tao K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Wang J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Wu K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Cao Y; Department of Digestive Surgical Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Cai K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
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Źródło:
Disease markers [Dis Markers] 2023 Feb 18; Vol. 2023, pp. 5178750. Date of Electronic Publication: 2023 Feb 18 (Print Publication: 2023).
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/genetics
Humans ; Bayes Theorem ; Retrospective Studies ; Area Under Curve
Czasopismo naukowe
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