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Tytuł :
Functional reciprocity of proteins involved in mitosis and endocytosis.
Autorzy :
Yu H; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Li Y; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Li L; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Huang J; Department of Genetics, University of Essex, UK.
Wang X; The High School Attached to Hunan Normal University, Changsha, China.
Tang R; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Jiang Z; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Lv L; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Chen F; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yu C; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yuan K; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.; The Biobank of Xiangya Hospital, Central South University, Changsha, China.
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Źródło :
The FEBS journal [FEBS J] 2021 Oct; Vol. 288 (20), pp. 5850-5866. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endocytosis*
Mitosis*
Endosomal Sorting Complexes Required for Transport/*metabolism
Transcription Factors/*metabolism
Animals ; Caveolins/metabolism ; Clathrin/metabolism ; Humans
Czasopismo naukowe
Tytuł :
Regulatory mechanism of cyclins and cyclin-dependent kinases in post-mitotic neuronal cell division.
Autorzy :
Gupta R; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Jha A; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Ambasta RK; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Kumar P; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 120006. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mitosis*
Cyclin-Dependent Kinases/*metabolism
Cyclins/*metabolism
Neurodegenerative Diseases/*metabolism
Neurodegenerative Diseases/*pathology
Neurons/*metabolism
Neurons/*pathology
Acetylation ; Animals ; Histone Deacetylases/metabolism ; Humans ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Disruption of desmosome function leads to increased centrosome clustering in 14-3-3γ-knockout cells with supernumerary centrosomes.
Autorzy :
Tilwani S; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.; Homi Bhabha National Institute, Training School Complex, Mumbai, India.
Gandhi K; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.
Narayan S; Department of Chemical Sciences, TIFR, Mumbai, India.
Ainavarapu SRK; Department of Chemical Sciences, TIFR, Mumbai, India.
Dalal SN; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.; Homi Bhabha National Institute, Training School Complex, Mumbai, India.
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Źródło :
FEBS letters [FEBS Lett] 2021 Nov; Vol. 595 (21), pp. 2675-2690. Date of Electronic Publication: 2021 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
14-3-3 Proteins*
Centrosome*
Desmosomes*
Mitosis*
HCT116 Cells ; Humans ; Spindle Apparatus
Czasopismo naukowe
Tytuł :
Novel photochromic inhibitor for mitotic kinesin Eg5 which forms multiple isomerization states.
Autorzy :
Alrazi IM; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
Sadakane K; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
Maruta S; Department of Biosciences, Graduate School of Science and Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan.
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Źródło :
Journal of biochemistry [J Biochem] 2021 Oct 11; Vol. 170 (2), pp. 229-237.
Typ publikacji :
Journal Article
MeSH Terms :
Mitosis*
Azo Compounds/*pharmacology
Benzopyrans/*pharmacology
Indoles/*pharmacology
Kinesin/*antagonists & inhibitors
Kinesin/*metabolism
Nitro Compounds/*pharmacology
Adenosine Triphosphatases/metabolism ; Azo Compounds/chemistry ; Azo Compounds/metabolism ; Benzopyrans/chemistry ; Benzopyrans/metabolism ; Cell Division/drug effects ; Cell Movement/drug effects ; Humans ; Indoles/chemistry ; Indoles/metabolism ; Isomerism ; Kinesin/chemistry ; Light ; Luminescent Agents/pharmacology ; Microtubules/metabolism ; Nitro Compounds/chemistry ; Nitro Compounds/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms.
Autorzy :
Lee HS; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Korea. .
Min S; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Korea.
Jung YE; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Chae S; Institute of Medical Science, Ajou University School of Medicine, Suwon, 16499, Korea.
Heo J; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, 16499, Korea.
Lee JH; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Korea.; Institute of Medical Science, Ajou University School of Medicine, Suwon, 16499, Korea.
Kim T; Department of Life Science, Ewha Womans University, Seoul, 03760, Korea.
Kang HC; Department of Physiology, Ajou University School of Medicine, Suwon, Korea.
Nakanish M; Division of Cancer Cell Biology, The University of Tokyo, Tokyo, 108-8639, Japan.
Cha SS; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Cho H; Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Korea. .
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Źródło :
Nature communications [Nat Commun] 2021 Oct 11; Vol. 12 (1), pp. 5931. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Segregation*
Mitosis*
Aurora Kinase B/*genetics
Cell Cycle Proteins/*genetics
Nuclear Proteins/*genetics
Protein-Serine-Threonine Kinases/*genetics
Proto-Oncogene Proteins/*genetics
Signal Transduction/*genetics
Trans-Activators/*genetics
Aspartic Acid/metabolism ; Aurora Kinase B/metabolism ; Cell Cycle Proteins/metabolism ; Chromatin/chemistry ; Chromatin/metabolism ; Feedback, Physiological ; Gene Expression Regulation ; HeLa Cells ; Histones/genetics ; Histones/metabolism ; Humans ; Kinetochores/metabolism ; Kinetochores/ultrastructure ; Microtubules/metabolism ; Microtubules/ultrastructure ; Nuclear Proteins/deficiency ; Phosphorylation ; Protein-Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/metabolism ; Serine/metabolism ; Trans-Activators/deficiency
Czasopismo naukowe
Tytuł :
Improving precise counting of mitotic cells in mantle cell lymphoma using phosphohistone H3 (PHH3) antibody.
Autorzy :
Medani H; Department of Cellular & Molecular Pathology, Northwest London Pathology, Imperial College Healthcare NHS Trust, London, London, UK.
Elshiekh M; Department of Cellular & Molecular Pathology, Northwest London Pathology, Imperial College Healthcare NHS Trust, London, London, UK.
Naresh KN; Department of Cellular & Molecular Pathology, Northwest London Pathology, Imperial College Healthcare NHS Trust, London, London, UK .; Centre for Haematology, Department of Immunology & Inflammation, Imperial College London, London, London, UK.
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2021 Oct; Vol. 74 (10), pp. 646-649. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Immunohistochemistry*
Mitosis*
Mitotic Index*
Biomarkers, Tumor/*analysis
Histones/*analysis
Lymphoma, Mantle-Cell/*chemistry
Aged ; Aged, 80 and over ; Cell Count ; Female ; Humans ; Ki-67 Antigen/analysis ; Lymphoma, Mantle-Cell/pathology ; Male ; Middle Aged ; Phosphorylation ; Predictive Value of Tests ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.
Autorzy :
Llorens-Agost M; Radiation Biology and DNA Repair, Technical University of Darmstadt, Darmstadt, Germany.
Ensminger M; Radiation Biology and DNA Repair, Technical University of Darmstadt, Darmstadt, Germany.
Le HP; Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA, USA.
Gawai A; Radiation Biology and DNA Repair, Technical University of Darmstadt, Darmstadt, Germany.
Liu J; Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA, USA.
Cruz-García A; Radiation Biology and DNA Repair, Technical University of Darmstadt, Darmstadt, Germany.
Bhetawal S; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, USA.
Wood RD; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, USA.
Heyer WD; Department of Microbiology and Molecular Genetics, University of California, Davis, Davis, CA, USA.
Löbrich M; Radiation Biology and DNA Repair, Technical University of Darmstadt, Darmstadt, Germany. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 Oct; Vol. 23 (10), pp. 1095-1104. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
DNA End-Joining Repair*
Homologous Recombination*
Mitosis*
BRCA2 Protein/*metabolism
DNA-Directed DNA Polymerase/*metabolism
Rad52 DNA Repair and Recombination Protein/*metabolism
BRCA2 Protein/genetics ; Cell Cycle ; DNA-Directed DNA Polymerase/genetics ; HeLa Cells ; Humans ; Rad52 DNA Repair and Recombination Protein/genetics
Czasopismo naukowe
Tytuł :
Using Budding Yeast to Identify Molecules That Block Cancer Cell 'Mitotic Slippage' Only in the Presence of Mitotic Poisons.
Autorzy :
Schuyler SC; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan.; Division of Head and Neck Surgery, Department of Otolaryngology, Chang Gung Memorial Hospital, Kwei-Shan, Taoyuan 333, Taiwan.
Chen HY; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Apoptosis*/drug effects
Apoptosis*/genetics
Cell Cycle Checkpoints*/drug effects
Cell Cycle Checkpoints*/genetics
Mitosis*/drug effects
Mitosis*/genetics
Neoplasms*/genetics
Neoplasms*/metabolism
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Antineoplastic Agents/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Drug Screening Assays, Antitumor ; Humans ; Poisons/chemistry ; Poisons/pharmacology
Czasopismo naukowe
Tytuł :
Genetic Instability Due to Spindle Anomalies Visualized in Mutants of Dictyostelium .
Autorzy :
Ecke M; Cell Dynamics Group, Max Planck Institute of Biochemistry, am Klopferspitz 18, D-82152 Martinsried, Germany.
Prassler J; Cell Dynamics Group, Max Planck Institute of Biochemistry, am Klopferspitz 18, D-82152 Martinsried, Germany.
Gerisch G; Cell Dynamics Group, Max Planck Institute of Biochemistry, am Klopferspitz 18, D-82152 Martinsried, Germany.
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Źródło :
Cells [Cells] 2021 Aug 29; Vol. 10 (9). Date of Electronic Publication: 2021 Aug 29.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Chromosome Segregation*
Genomic Instability*
Mitosis*
Mutation*
Dictyostelium/*genetics
Spindle Apparatus/*genetics
Dictyostelium/growth & development ; Dictyostelium/metabolism ; Microtubules/genetics ; Microtubules/metabolism ; Spindle Apparatus/metabolism ; Spindle Apparatus/pathology ; rac GTP-Binding Proteins/genetics ; rac GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines.
Autorzy :
Di Bari M; Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy.
Tombolillo V; Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy.
Alessandrini F; Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy.
Guerriero C; Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy.
Fiore M; Institute of Molecular Biology and Pathology, CNR, 00185 Rome, Italy.
Asteriti IA; Institute of Molecular Biology and Pathology, CNR, 00185 Rome, Italy.
Castigli E; Department of Experimental Medicine, Section of Physiology and Biochemistry, University of Perugia, 06100 Perugia, Italy.
Sciaccaluga M; Department of Medicine and Surgery, University of Perugia, 06100 Perugia, Italy.
Guarguaglini G; Institute of Molecular Biology and Pathology, CNR, 00185 Rome, Italy.
Degrassi F; Institute of Molecular Biology and Pathology, CNR, 00185 Rome, Italy.
Tata AM; Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy.; Research Centre of Neurobiology Daniel Bovet, 00185 Rome, Italy.
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Źródło :
Cells [Cells] 2021 Jul 08; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Glioblastoma/*metabolism
Glioblastoma/*pathology
Receptor, Muscarinic M2/*metabolism
Spindle Apparatus/*metabolism
Acetylation/drug effects ; Arecoline/analogs & derivatives ; Arecoline/pharmacology ; Cell Line, Tumor ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Humans ; Metaphase/drug effects ; Sirtuin 2/metabolism ; Time-Lapse Imaging ; Tubulin/metabolism
Czasopismo naukowe
Tytuł :
Formation of artificial chromosomes in Caenorhabditis elegans and analyses of their segregation in mitosis, DNA sequence composition and holocentromere organization.
Autorzy :
Lin Z; School of Biological Sciences, the University of Hong Kong, Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong.
Xie Y; School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong.
Nong W; School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong.
Ren X; Department of Biology, Baptist University of Hong Kong, Sir Run Run Shaw Building, Ho Sin Hang Campus, Kowloon Tong, Hong Kong.
Li R; Department of Biology, Baptist University of Hong Kong, Sir Run Run Shaw Building, Ho Sin Hang Campus, Kowloon Tong, Hong Kong.
Zhao Z; Department of Biology, Baptist University of Hong Kong, Sir Run Run Shaw Building, Ho Sin Hang Campus, Kowloon Tong, Hong Kong.
Hui JHL; School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong.
Yuen KWY; School of Biological Sciences, the University of Hong Kong, Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Sep 20; Vol. 49 (16), pp. 9174-9193.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Segregation*
Mitosis*
Chromosomes, Artificial/*genetics
Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/metabolism ; Centromere/genetics ; Centromere/metabolism ; GC Rich Sequence ; Heat-Shock Proteins/metabolism ; Protein Binding ; Saccharomyces cerevisiae
Czasopismo naukowe
Tytuł :
Dual role of Fam208a during zygotic cleavage and early embryonic development.
Autorzy :
Gresakova V; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic; Palacky University in Olomouc, Faculty of Medicine and Dentistry, Hněvotínská 3, 775 15, Olomouc, Czech Republic. Electronic address: .
Novosadova V; Czech Centre of Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic. Electronic address: .
Prochazkova M; Czech Centre of Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic. Electronic address: .
Prochazka J; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic; Czech Centre of Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic. Electronic address: .
Sedlacek R; Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic; Czech Centre of Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prumyslova 595, 252 50, Vestec, Czech Republic. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Sep 15; Vol. 406 (2), pp. 112723. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Embryonic Development*
Epigenesis, Genetic*
Genomic Instability*
Mitosis*
Nuclear Proteins/*physiology
Phosphoproteins/*metabolism
Zygote/*physiology
Animals ; CRISPR-Cas Systems ; DNA Methylation ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nuclear Proteins/antagonists & inhibitors ; Phosphoproteins/genetics ; Pregnancy
Czasopismo naukowe
Tytuł :
Cep192, a Novel Missing Link between the Centrosomal Core and Corona in Dictyostelium Amoebae.
Autorzy :
Pitzen V; Department of Cell Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
Sander S; Department of Cell Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
Baumann O; Department of Animal Physiology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
Gräf R; Department of Cell Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
Meyer I; Department of Cell Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
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Źródło :
Cells [Cells] 2021 Sep 10; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Centrosome/*metabolism
Chromosomal Proteins, Non-Histone/*metabolism
Dictyostelium/*metabolism
Microtubules/*metabolism
Protozoan Proteins/*metabolism
Chromosomal Proteins, Non-Histone/genetics ; Dictyostelium/growth & development ; Protozoan Proteins/genetics ; Spindle Apparatus
Czasopismo naukowe
Tytuł :
Aurora A kinase activation: Different means to different ends.
Autorzy :
Tavernier N; Programme équipe Labellisée Ligue Contre le Cancer - Université de Paris, Centre National de la Recherche Scientifique, Institut Jacques Monod, Paris, France.
Sicheri F; Centre for Systems Biology, Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
Pintard L; Programme équipe Labellisée Ligue Contre le Cancer - Université de Paris, Centre National de la Recherche Scientifique, Institut Jacques Monod, Paris, France.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Sep 06; Vol. 220 (9). Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Protein Processing, Post-Translational*
Aurora Kinase A/*genetics
Cell Cycle Proteins/*genetics
Microtubule-Associated Proteins/*genetics
Allosteric Regulation ; Animals ; Aurora Kinase A/metabolism ; Cell Cycle Proteins/metabolism ; Eukaryotic Cells/cytology ; Eukaryotic Cells/enzymology ; Humans ; Microtubule-Associated Proteins/metabolism ; Microtubules/metabolism ; Microtubules/ultrastructure ; Oxidation-Reduction ; Phosphorylation ; Protein Binding ; Signal Transduction ; Spindle Apparatus/metabolism ; Spindle Apparatus/ultrastructure
Czasopismo naukowe
Tytuł :
Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells.
Autorzy :
Amaya C; Department of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Papanicolaou Building, Room 415 [M877], 1550 NW 10th Avenue, Miami, FL, 33136, USA.
Luo S; Department of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Papanicolaou Building, Room 415 [M877], 1550 NW 10th Avenue, Miami, FL, 33136, USA.
Baigorri J; HHMI High School Scholars Program, Department of Undergraduate Research and Community Outreach, University of Miami, Miami, FL, 33146, USA.
Baucells R; HHMI High School Scholars Program, Department of Undergraduate Research and Community Outreach, University of Miami, Miami, FL, 33146, USA.
Smith ER; Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
Xu XX; Department of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Papanicolaou Building, Room 415 [M877], 1550 NW 10th Avenue, Miami, FL, 33136, USA. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Sep 01; Vol. 21 (1), pp. 981. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Mitosis*
Ultrasonic Waves*
Breast Neoplasms/*pathology
Microtubules/*pathology
Ovarian Neoplasms/*pathology
Paclitaxel/*pharmacology
Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis ; Breast Neoplasms/drug therapy ; Breast Neoplasms/radiotherapy ; Cell Proliferation ; Cytoskeleton/metabolism ; Female ; Humans ; Microtubules/drug effects ; Microtubules/radiation effects ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/radiotherapy ; Tubulin/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
CTCF and transcription influence chromatin structure re-configuration after mitosis.
Autorzy :
Zhang H; Institute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China. .; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. .
Lam J; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhang D; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lan Y; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Vermunt MW; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Keller CA; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
Giardine B; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
Hardison RC; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
Blobel GA; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. .; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 27; Vol. 12 (1), pp. 5157. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mitosis*
Transcription, Genetic*
CCCTC-Binding Factor/*metabolism
Chromatin/*metabolism
Animals ; CCCTC-Binding Factor/genetics ; Cell Division ; Cell Line ; Chromatin/genetics ; Chromatin Assembly and Disassembly ; Enhancer Elements, Genetic ; Mice ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł :
USP48 Governs Cell Cycle Progression by Regulating the Protein Level of Aurora B.
Autorzy :
Antao AM; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Kaushal K; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Das S; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Singh V; Department of Biosciences, School of Science, Indrashil University, Rajpur, Ahmedabad 382740, Gujarat, India.
Suresh B; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.
Kim KS; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.; College of Medicine, Hanyang University, Seoul 04763, Korea.
Ramakrishna S; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea.; College of Medicine, Hanyang University, Seoul 04763, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 07; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cytokinesis*
Mitosis*
Aurora Kinase B/*metabolism
Ubiquitin-Specific Proteases/*metabolism
Aurora Kinase B/genetics ; Enzyme Stability ; HEK293 Cells ; HeLa Cells ; Humans ; Ubiquitin-Specific Proteases/genetics
Czasopismo naukowe
Tytuł :
HMGB2 orchestrates mitotic clonal expansion by binding to the promoter of C/EBPβ to facilitate adipogenesis.
Autorzy :
Chen K; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Zhang J; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Liang F; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Zhu Q; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Cai S; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Tong X; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
He Z; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Liu X; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Chen Y; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China. .
Mo D; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China. .
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Źródło :
Cell death & disease [Cell Death Dis] 2021 Jul 02; Vol. 12 (7), pp. 666. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipogenesis*
Mitosis*
Promoter Regions, Genetic*
Adipocytes, White/*metabolism
Adipose Tissue, White/*metabolism
CCAAT-Enhancer-Binding Protein-beta/*metabolism
HMGB2 Protein/*metabolism
Obesity/*metabolism
Adipocytes, White/pathology ; Adipose Tissue, White/pathology ; Animals ; Binding Sites ; CCAAT-Enhancer-Binding Protein-beta/genetics ; Cells, Cultured ; Diet, High-Fat ; Disease Models, Animal ; Female ; Gene Expression Regulation ; HMGB2 Protein/genetics ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Obesity/genetics ; Obesity/pathology ; Signal Transduction ; Weight Gain
Czasopismo naukowe
Tytuł :
Biomarkers of geno- and cytotoxicity in the native broad-snouted caiman (Caiman latirostris): Chromosomal aberrations and mitotic index.
Autorzy :
Chacón CF; Proyecto Yacaré- Lab. Zoología Aplicada: Anexo Vertebrados (FHUC-UNL/MAyCC), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina; Laboratorio de Ecología Molecular Aplicada (LEMA) - Instituto de Ciencias Veterinarias del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (ICiVet Litoral-CONICET/UNL), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina. Electronic address: .
López González EC; Proyecto Yacaré- Lab. Zoología Aplicada: Anexo Vertebrados (FHUC-UNL/MAyCC), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina; Laboratorio de Ecología Molecular Aplicada (LEMA) - Instituto de Ciencias Veterinarias del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (ICiVet Litoral-CONICET/UNL), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina. Electronic address: .
Poletta GL; Proyecto Yacaré- Lab. Zoología Aplicada: Anexo Vertebrados (FHUC-UNL/MAyCC), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina; Laboratorio de Ecología Molecular Aplicada (LEMA) - Instituto de Ciencias Veterinarias del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (ICiVet Litoral-CONICET/UNL), Av. Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina; Cát. Toxicol., Farmacol. y Bioq. Legal (FBCB-UNL, CONICET), Ciudad Universitaria - Paraje El Pozo S/N (3000), Santa Fe, Argentina. Electronic address: .
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Źródło :
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2021 Jul; Vol. 867, pp. 503353. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alkylating Agents/*toxicity
Alligators and Crocodiles/*genetics
Biomarkers/*metabolism
Chromosome Aberrations/*drug effects
Chromosomes/*drug effects
Mitosis/*drug effects
Animals ; Cells, Cultured ; Chromatids/drug effects ; Chromatids/genetics ; Chromosomes/genetics ; Lymphocytes/drug effects ; Micronucleus Tests/methods ; Mitosis/genetics ; Mitotic Index/methods
Czasopismo naukowe
Tytuł :
LMBD1 protein participates in cell mitosis by regulating microtubule assembly.
Autorzy :
Sun CY; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Chang SC; Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wang HP; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lee YJ; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Pan KH; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin CL; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsieh YT; Department of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.; Department of Medical Research, Chang Gung Memorial Hospital, Keelung, Taiwan.
Ta YC; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chen YH; Department of Chemistry, Tamkang University, New Taipei City, Taiwan.
Chang MF; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
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Źródło :
The Biochemical journal [Biochem J] 2021 Jun 25; Vol. 478 (12), pp. 2321-2337.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Cytoskeleton/*physiology
Microtubules/*physiology
Nucleocytoplasmic Transport Proteins/*metabolism
Nucleocytoplasmic Transport Proteins/*physiology
Tubulin/*chemistry
Animals ; Cell Cycle ; Embryo, Mammalian/cytology ; Embryo, Mammalian/metabolism ; Female ; Fibroblasts/cytology ; Fibroblasts/metabolism ; HeLa Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nucleocytoplasmic Transport Proteins/genetics ; Protein Interaction Domains and Motifs ; Spindle Apparatus/physiology
Czasopismo naukowe

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