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Wyszukujesz frazę ""MONOAMINE oxidase inhibitors"" wg kryterium: Temat


Tytuł :
Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation.
Autorzy :
Ayoup MS; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria, 21321, Egypt. Electronic address: .
Abu-Serie MM; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Egypt.
Awad LF; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria, 21321, Egypt.
Teleb M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Ragab HM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Amer A; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria, 21321, Egypt; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah, Saudi Arabia. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 15; Vol. 222, pp. 113558. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Antineoplastic Agents/*pharmacology
Colorectal Neoplasms/*drug therapy
Matrix Metalloproteinase Inhibitors/*pharmacology
Monoamine Oxidase Inhibitors/*pharmacology
Quinoxalines/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line ; Cell Proliferation/drug effects ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase Inhibitors/chemical synthesis ; Matrix Metalloproteinase Inhibitors/chemistry ; Molecular Structure ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Quinoxalines/chemical synthesis ; Quinoxalines/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Three -(pyridin-2-yl)-2-(pyridin-2-ylimino)thiazolidin-4-one as a novel inhibitor of cerebral MAO-B activity with antioxidant properties and low toxicity potential.
Autorzy :
Carraro Junior LR; Programa de Pós-graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Bioquímica e Neurofarmacologia Molecular (LABIONEM), Grupo de Pesquisa em Neurobiotecnologia (GPN), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brasil.
Alves AG; Programa de Pós-graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Bioquímica e Neurofarmacologia Molecular (LABIONEM), Grupo de Pesquisa em Neurobiotecnologia (GPN), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brasil.
Rech TDST; Programa de Pós-graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Bioquímica e Neurofarmacologia Molecular (LABIONEM), Grupo de Pesquisa em Neurobiotecnologia (GPN), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brasil.
Campos Júnior JC; Programa de Pós-Graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Química Aplicada a Bioativos (LaQuiABio), Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Universidade Federal de Pelotas, UFPel, Pelotas, RS, Brasil.
Siqueira GM; Programa de Pós-Graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Química Aplicada a Bioativos (LaQuiABio), Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Universidade Federal de Pelotas, UFPel, Pelotas, RS, Brasil.
Cunico W; Programa de Pós-Graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Química Aplicada a Bioativos (LaQuiABio), Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Universidade Federal de Pelotas, UFPel, Pelotas, RS, Brasil.
Brüning CA; Programa de Pós-graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Bioquímica e Neurofarmacologia Molecular (LABIONEM), Grupo de Pesquisa em Neurobiotecnologia (GPN), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brasil.
Bortolatto CF; Programa de Pós-graduação em Bioquímica e Bioprospecção (PPGBBio), Laboratório de Bioquímica e Neurofarmacologia Molecular (LABIONEM), Grupo de Pesquisa em Neurobiotecnologia (GPN), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brasil.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Aug; Vol. 35 (8), pp. e22833. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*enzymology
Free Radical Scavengers/*pharmacology
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Animals ; Brain Diseases/drug therapy ; Brain Diseases/enzymology ; Female ; Free Radical Scavengers/adverse effects ; Free Radical Scavengers/chemical synthesis ; Free Radical Scavengers/chemistry ; Male ; Mice ; Monoamine Oxidase Inhibitors/adverse effects ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry
Czasopismo naukowe
Tytuł :
Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease.
Autorzy :
Mathew GE; Department of Pharmacology, Grace College of Pharmacy, Palakkad, Kerala, India.; Department of Pharmaceutical Chemistry, Vinayaka Mission's College of Pharmacy, Vinayaka Mission's Research Foundation (Deemed to be a University), Tamilnadu, Salem, India.
Oh JM; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
Mohan K; Department of Pharmaceutical Chemistry, Vinayaka Mission's College of Pharmacy, Vinayaka Mission's Research Foundation (Deemed to be a University), Tamilnadu, Salem, India.
Tengli A; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.
Mathew B; Department of Pharmaceutical Chemistry, Division of Drug Design and Medicinal Chemistry Research Lab, Ahalia School of Pharmacy, Palakkad, Kerala, India.
Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Aug; Vol. 39 (13), pp. 4786-4794. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Monoamine Oxidase Inhibitors*/pharmacology
Parkinson Disease*/drug therapy
Animals ; Chlorocebus aethiops ; Kinetics ; Molecular Docking Simulation ; Monoamine Oxidase ; Structure-Activity Relationship ; Vero Cells
Czasopismo naukowe
Tytuł :
Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer's disease agents.
Autorzy :
Mzezewa SC; Department of Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Bellville, South Africa.
Omoruyi SI; Department of Medical Biosciences, University of the Western Cape, Bellville, South Africa.
Zondagh LS; Department of Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Bellville, South Africa.
Malan SF; Department of Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Bellville, South Africa.
Ekpo OE; Department of Medical Biosciences, University of the Western Cape, Bellville, South Africa.
Joubert J; Department of Pharmaceutical Chemistry, School of Pharmacy, University of the Western Cape, Bellville, South Africa.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1607-1621.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Alzheimer Disease/*drug therapy
Coumarins/*pharmacology
Monoamine Oxidase Inhibitors/*pharmacology
Neuroprotective Agents/*pharmacology
Alzheimer Disease/metabolism ; Cell Line, Tumor ; Coumarins/chemical synthesis ; Coumarins/chemistry ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.
Autorzy :
Sasidharan R; College of Pharmaceutical Science, Government T.D. Medical College, Alappuzha, India.; Organic Chemistry Division, SAS, VIT University, Vellore, India.
Eom BH; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
Heo JH; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
Park JE; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
Abdelgawad MA; Pharmaceutical Chemistry Department, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni Suef, Egypt.
Musa A; Department of Pharmacogonosy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.; Department of Pharmacogonosy, Al-Azhar University, Cairo, Egypt.
Gambacorta N; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', Bari, Italy.
Nicolotti O; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', Bari, Italy.
Manju SL; Organic Chemistry Division, SAS, VIT University, Vellore, India.
Mathew B; Division of Drug Design and Medicinal Chemistry Research Lab, Department of Pharmaceutical Chemistry, Ahalia School of Pharmacy, Palakkad, India.
Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 188-197.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcholinesterase/*metabolism
Chalcones/*pharmacology
Cholinesterase Inhibitors/*pharmacology
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Morpholines/*pharmacology
Animals ; Chalcones/chemical synthesis ; Chalcones/chemistry ; Chlorocebus aethiops ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; HeLa Cells ; Humans ; Hydrogen Peroxide/antagonists & inhibitors ; Hydrogen Peroxide/pharmacology ; Molecular Docking Simulation ; Molecular Structure ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Morpholines/chemistry ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Vero Cells
Czasopismo naukowe
Tytuł :
Monoamine Oxidase Inhibition by Major Tanshinones from Salvia miltiorrhiza and Selective Muscarinic Acetylcholine M 4 Receptor Antagonism by Tanshinone I.
Autorzy :
Prajapati R; Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.
Park SE; Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.; Department of Biomedical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan, Seoul 05505, Korea.
Seong SH; Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.; Natural Product Research Division, Honam National Institute of Biological Resource, Mokpo 58762, Korea.
Paudel P; Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.; National Center for Natural Products Research, Research Institute of Pharmaceutical Science, The University of Mississippi, Oxford, MS 38677, USA.
Fauzi FM; Department of Pharmacology and Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam 42300, Malaysia.
Jung HA; Department of Food Science and Human Nutrition, Jeonbok National University, Jeonju 54896, Korea.
Choi JS; Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.
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Źródło :
Biomolecules [Biomolecules] 2021 Jul 08; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Abietanes*/chemistry
Abietanes*/pharmacology
Monoamine Oxidase*/chemistry
Monoamine Oxidase*/genetics
Monoamine Oxidase*/metabolism
Monoamine Oxidase Inhibitors*/chemistry
Monoamine Oxidase Inhibitors*/pharmacology
Phenanthrenes*/chemistry
Phenanthrenes*/pharmacology
Receptor, Muscarinic M4*/antagonists & inhibitors
Receptor, Muscarinic M4*/chemistry
Receptor, Muscarinic M4*/genetics
Receptor, Muscarinic M4*/metabolism
Salvia miltiorrhiza/*chemistry
Animals ; CHO Cells ; Cricetulus ; Humans
Czasopismo naukowe
Tytuł :
Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents.
Autorzy :
Ye C; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Xu R; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Cao Z; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Song Q; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Yu G; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Shi Y; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Liu Z; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Liu X; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address: .
Deng Y; Department of Medicinal Chemistry, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2021 Jun; Vol. 111, pp. 104895. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Design*
Alzheimer Disease/*drug therapy
Cholinesterase Inhibitors/*pharmacology
Monoamine Oxidase Inhibitors/*pharmacology
Neuroprotective Agents/*pharmacology
Phthalazines/*pharmacology
Acetylcholinesterase/metabolism ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/metabolism ; Animals ; Butyrylcholinesterase/metabolism ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Electrophorus ; Humans ; Molecular Structure ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Peptide Fragments/antagonists & inhibitors ; Peptide Fragments/metabolism ; Phthalazines/chemical synthesis ; Phthalazines/chemistry ; Platelet Aggregation/drug effects ; Protein Aggregates/drug effects ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Monoamine oxidase inhibitors (MAOI): pharmacology, metabolism and application in the treatment of depression
Autorzy :
Grabowski Ł; Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Filozofii i Nauk Społecznych, Instytut Psychologii, Katedra Psychologii Klinicznej i Neuropsychologii. .
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Transliterated Title :
Inhibitory monoaminooksydazy (IMAO): farmakologia, metabolizm i zastosowanie w terapii depresji o różnej etiologii.
Źródło :
Postepy biochemii [Postepy Biochem] 2021 May 25; Vol. 67 (2), pp. 130-140. Date of Electronic Publication: 2021 May 25 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Depression*/drug therapy
Monoamine Oxidase Inhibitors*/pharmacology
Monoamine Oxidase Inhibitors*/therapeutic use
Humans ; Moclobemide ; Monoamine Oxidase
Czasopismo naukowe
Tytuł :
Curcumin-Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders.
Autorzy :
Quezada E; Department of Organic Chemistry, Faculty of Pharmacy, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Rodríguez-Enríquez F; Center for Research in Molecular Medicine and Chronic Disease (CIMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Laguna R; Center for Research in Molecular Medicine and Chronic Disease (CIMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Cutrín E; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Otero F; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Uriarte E; Department of Organic Chemistry, Faculty of Pharmacy, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Instituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile, Santiago 7500912, Chile.
Viña D; Center for Research in Molecular Medicine and Chronic Disease (CIMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*chemical synthesis
Cholinesterase Inhibitors/*chemical synthesis
Coumarins/*chemical synthesis
Curcumin/*analogs & derivatives
Monoamine Oxidase Inhibitors/*chemical synthesis
Neuroprotective Agents/*chemical synthesis
Acetylcholinesterase/metabolism ; Animals ; Antioxidants/pharmacology ; Biphenyl Compounds/antagonists & inhibitors ; Butyrylcholinesterase/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cholinesterase Inhibitors/pharmacology ; Coumarins/pharmacology ; Curcumin/pharmacology ; GPI-Linked Proteins/metabolism ; Humans ; Hydrogen Peroxide/antagonists & inhibitors ; Hydrogen Peroxide/pharmacology ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Motor Cortex/cytology ; Motor Cortex/enzymology ; Nanoparticles/chemistry ; Neurons/cytology ; Neurons/drug effects ; Neurons/enzymology ; Neuroprotective Agents/pharmacology ; Picrates/antagonists & inhibitors ; Primary Cell Culture ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B.
Autorzy :
Mazej T; Faculty of Pharmacy, University of Ljubljana, Aškerčeva Cesta 7, SI-1000 Ljubljana, Slovenia.
Knez D; Faculty of Pharmacy, University of Ljubljana, Aškerčeva Cesta 7, SI-1000 Ljubljana, Slovenia.
Meden A; Faculty of Pharmacy, University of Ljubljana, Aškerčeva Cesta 7, SI-1000 Ljubljana, Slovenia.
Gobec S; Faculty of Pharmacy, University of Ljubljana, Aškerčeva Cesta 7, SI-1000 Ljubljana, Slovenia.
Sova M; Faculty of Pharmacy, University of Ljubljana, Aškerčeva Cesta 7, SI-1000 Ljubljana, Slovenia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 06; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Butyrylcholinesterase/*chemistry
Cholinesterase Inhibitors/*pharmacology
Monoamine Oxidase/*chemistry
Monoamine Oxidase Inhibitors/*pharmacology
Piperidines/*chemistry
Cholinesterase Inhibitors/chemistry ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Structure ; Monoamine Oxidase Inhibitors/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Trace Amine-Associated Receptor 1 Regulates Central Effects of Monoamine Oxidase Inhibitors: Involvement of Tyramine and Glutamate.
Autorzy :
Gautron S; Institute of Biology Paris-Seine, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Sorbonne Université, Paris, France. Electronic address: .
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Źródło :
Biological psychiatry [Biol Psychiatry] 2021 Jul 01; Vol. 90 (1), pp. 2-3.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Monoamine Oxidase*
Monoamine Oxidase Inhibitors*/pharmacology
Glutamic Acid ; Receptors, G-Protein-Coupled ; Tyramine
Czasopismo naukowe
Tytuł :
Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies.
Autorzy :
Tarpley M; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA.
Oladapo HO; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA; INBS PhD Program, North Carolina Central University, Durham, NC 27707, USA.
Strepay D; Department of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC 27707, USA.
Caligan TB; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA.
Chdid L; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA.
Shehata H; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA; INBS PhD Program, North Carolina Central University, Durham, NC 27707, USA.
Roques JR; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27514, USA.
Thomas R; Department of Pharmaceutical Sciences; North Carolina Central University, Durham, NC 27707, USA.
Laudeman CP; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA.
Onyenwoke RU; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA; Department of Pharmaceutical Sciences; North Carolina Central University, Durham, NC 27707, USA.
Darr DB; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27514, USA.
Williams KP; Biomanufacturing Research Institute and Technology Enterprise, North Carolina Central University, Durham, NC 27707, USA; Department of Pharmaceutical Sciences; North Carolina Central University, Durham, NC 27707, USA. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Jul 01; Vol. 162, pp. 105821. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Monoamine Oxidase Inhibitors*/pharmacology
Neoplasms*
Antineoplastic Agents/*pharmacology
Protein-Serine-Threonine Kinases/*antagonists & inhibitors
Protein-Tyrosine Kinases/*antagonists & inhibitors
Carbolines ; Harmine/pharmacology ; High-Throughput Screening Assays ; Humans ; Monoamine Oxidase
Czasopismo naukowe
Tytuł :
TAAR1-Dependent and -Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition.
Autorzy :
Mantas I; Department of Neurology and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address: .
Vallianatou T; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden.
Yang Y; Department of Neurology and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Shariatgorji M; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden; National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Kalomoiri M; Department of Neurology and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Fridjonsdottir E; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden.
Millan MJ; Centre for Therapeutic Innovation-CNS, Institut de Recherches Servier, Centre de Recherches de Croissy, Paris, France.
Zhang X; Department of Neurology and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Andrén PE; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden; National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Svenningsson P; Department of Neurology and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
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Źródło :
Biological psychiatry [Biol Psychiatry] 2021 Jul 01; Vol. 90 (1), pp. 16-27. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glutamic Acid*
Monoamine Oxidase Inhibitors*/pharmacology
Tyramine*
Receptors, G-Protein-Coupled/*physiology
Animals ; Mice ; Mice, Knockout ; Monoamine Oxidase
Czasopismo naukowe
Tytuł :
Evaluation of the inhibition of monoamine oxidase A by bioactive coffee compounds protecting serotonin degradation.
Autorzy :
Grzelczyk J; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland. Electronic address: .
Budryn G; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland. Electronic address: .
Peña-García J; Structural Bioinformatics and High-Performance Computing Research Group (BIO-HPC), Computer Science Department, Catholic University of Murcia (UCAM), Guadalupe, Murcia, Spain. Electronic address: .
Szwajgier D; Department of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences in Lublin, Lublin, Poland. Electronic address: .
Gałązka-Czarnecka I; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland. Electronic address: .
Oracz J; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland. Electronic address: .
Pérez-Sánchez H; Structural Bioinformatics and High-Performance Computing Research Group (BIO-HPC), Computer Science Department, Catholic University of Murcia (UCAM), Guadalupe, Murcia, Spain. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Jun 30; Vol. 348, pp. 129108. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Coffee/*chemistry
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Serotonin/*metabolism
Caffeine/analysis ; Chlorogenic Acid/analysis ; Diabetes Mellitus, Type 2/metabolism ; Monoamine Oxidase Inhibitors/chemistry ; Seeds/chemistry
Czasopismo naukowe
Tytuł :
Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy.
Autorzy :
Wang YC; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Wang X; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Yu J; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Ma F; Department of Molecular, Cell and Developmental Biology, and Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.
Li Z; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Zhou Y; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Zeng S; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Ma X; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Li YR; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Neal A; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Huang J; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
To A; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Clarke N; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Memarzadeh S; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; The VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, the David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA.
Pellegrini M; Department of Molecular, Cell and Developmental Biology, and Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.
Yang L; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA. .; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. .; Jonsson Comprehensive Cancer Center, the David Geffen School of Medicine, University of California, Los Angeles, CA, USA. .; Molecular Biology Institute, University of California, Los Angeles, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 10; Vol. 12 (1), pp. 3530. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy/*methods
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Neoplasms/*drug therapy
Tumor-Associated Macrophages/*drug effects
Tumor-Associated Macrophages/*metabolism
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/mortality ; Cell Line, Tumor ; Drug Synergism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Kaplan-Meier Estimate ; Lymphoma/genetics ; Lymphoma/metabolism ; Lymphoma/mortality ; Melanoma/genetics ; Melanoma/metabolism ; Melanoma/mortality ; Mice ; Mice, Inbred C57BL ; Monoamine Oxidase/deficiency ; Monoamine Oxidase/genetics ; Monoamine Oxidase Inhibitors/therapeutic use ; Neoplasms/genetics ; Neoplasms/immunology ; Neoplasms/mortality ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/mortality ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/metabolism ; RNA-Seq ; Reactive Oxygen Species/metabolism ; Single-Cell Analysis ; T-Lymphocytes/immunology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.
Autorzy :
Delogu GL; Department of Life and Environmental Sciences, University of Cagliari, 09042 Monserrato, Cagliari, Italy. Electronic address: .
Kumar A; Department of Electrical and Electronic Engineering, University of Cagliari 09123 Cagliari, Italy.
Gatto G; Department of Electrical and Electronic Engineering, University of Cagliari 09123 Cagliari, Italy.
Bustelo F; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Avda Barcelona s/n, Campus Vida 15782, Santiago de Compostela, Spain; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Saavedra LM; Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (IQM-CSIC), c/ Juan de la Cierva 3, E-28006 Madrid, Spain.
Rodríguez-Franco MI; Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (IQM-CSIC), c/ Juan de la Cierva 3, E-28006 Madrid, Spain.
Laguna R; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Avda Barcelona s/n, Campus Vida 15782, Santiago de Compostela, Spain.
Viña D; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Avda Barcelona s/n, Campus Vida 15782, Santiago de Compostela, Spain; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2021 Feb; Vol. 107, pp. 104616. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzofurans/*chemistry
Monoamine Oxidase/*chemistry
Monoamine Oxidase Inhibitors/*chemical synthesis
Benzofurans/metabolism ; Benzofurans/pharmacology ; Binding Sites ; Blood-Retinal Barrier/drug effects ; Blood-Retinal Barrier/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Molecular Docking Simulation ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Protein Structure, Tertiary ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
4-Oxoquinolines and monoamine oxidase: When tautomerism matters.
Autorzy :
Mesiti F; Dipartimento di Scienze Della Salute, Università'Magna Græcia' di Catanzaro, Campus Universitario 'S. Venuta', Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy; Net4Science Srl, Spin-off Accademico, Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy; CIQUP, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade Do Porto, Porto, 4169-007, Portugal.
Maruca A; Dipartimento di Scienze Della Salute, Università'Magna Græcia' di Catanzaro, Campus Universitario 'S. Venuta', Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy; Net4Science Srl, Spin-off Accademico, Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy.
Silva V; CIQUP, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade Do Porto, Porto, 4169-007, Portugal; UCIBIO-REQUIMTE, Laboratório de Toxicologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade Do Porto, 4050-313, Porto, Portugal.
Rocca R; Net4Science Srl, Spin-off Accademico, Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy; Dipartimento di Medicina Clinica e Sperimentale, Università'Magna Græcia' di Catanzaro, Campus Universitario 'S. Venuta', Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy.
Fernandes C; CIQUP, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade Do Porto, Porto, 4169-007, Portugal.
Remião F; UCIBIO-REQUIMTE, Laboratório de Toxicologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade Do Porto, 4050-313, Porto, Portugal.
Uriarte E; Departamento Química Orgánica, Facultad de Farmacia, Universidad de Santiago de Compostela, Campus Vida, 15782, Santiago de Compostela, España, Spain; Instituto de Ciencias Químicas Aplicadas, Universidad Autonoma de Chile, Av. Libertador Bernardo O'Higgins, 7500912, Santiago de Chile, Chile.
Alcaro S; Dipartimento di Scienze Della Salute, Università'Magna Græcia' di Catanzaro, Campus Universitario 'S. Venuta', Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy; Net4Science Srl, Spin-off Accademico, Viale Europa, Loc. Germaneto, 88100, Catanzaro, Italy. Electronic address: .
Gaspar A; CIQUP, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade Do Porto, Porto, 4169-007, Portugal. Electronic address: .
Borges F; CIQUP, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade Do Porto, Porto, 4169-007, Portugal. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Mar 05; Vol. 213, pp. 113183. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
4-Quinolones/*pharmacology
Antineoplastic Agents/*pharmacology
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
4-Quinolones/chemical synthesis ; 4-Quinolones/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Models, Molecular ; Molecular Structure ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Investigation of pyrazolo[1,5-a]quinoxalin-4-ones as novel monoamine oxidase inhibitors.
Autorzy :
Panova VA; Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University named after K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, Russian Federation. Electronic address: .
Filimonov SI; Yaroslavl State Technical University, 88 Moskovskii av., Yaroslavl, Russian Federation. Electronic address: .
Chirkova ZV; Yaroslavl State Technical University, 88 Moskovskii av., Yaroslavl, Russian Federation. Electronic address: .
Kabanova MV; Yaroslavl State Technical University, 88 Moskovskii av., Yaroslavl, Russian Federation. Electronic address: .
Shetnev AA; Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University named after K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, Russian Federation. Electronic address: .
Korsakov MK; Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University named after K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, Russian Federation. Electronic address: .
Petzer A; Pharmaceutical Chemistry and Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address: .
Petzer JP; Pharmaceutical Chemistry and Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address: .
Suponitsky KY; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov St. 28, Moscow 119991, Russian Federation; G.V. Plekhanov Russian University of Economics, Stremyanny per. 36, Moscow 117997, Russian Federation. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2021 Mar; Vol. 108, pp. 104563. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Quinoxalines/*pharmacology
Dose-Response Relationship, Drug ; Humans ; Models, Molecular ; Molecular Structure ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; Quinoxalines/chemical synthesis ; Quinoxalines/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Design, synthesis and biological evaluation of potential anti-AD hybrids with monoamine oxidase B inhibitory and iron-chelating effects.
Autorzy :
Guo J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China.
Mi Z; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China.
Jiang X; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China.
Zhang C; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China.
Guo Z; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China.
Li L; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China.
Gu J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China.
Zhou T; School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, PR China.
Bai R; College of Pharmacy, School of Medicine, Hangzhou Normal University, Hangzhou, PR China; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, PR China. Electronic address: .
Xie Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, PR China. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2021 Mar; Vol. 108, pp. 104564. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Design*
Alzheimer Disease/*drug therapy
Iron Chelating Agents/*pharmacology
Monoamine Oxidase/*metabolism
Monoamine Oxidase Inhibitors/*pharmacology
Alzheimer Disease/metabolism ; Animals ; Dose-Response Relationship, Drug ; Humans ; Iron Chelating Agents/chemical synthesis ; Iron Chelating Agents/chemistry ; Maze Learning/drug effects ; Mice ; Mice, Inbred ICR ; Models, Molecular ; Molecular Structure ; Monoamine Oxidase Inhibitors/chemical synthesis ; Monoamine Oxidase Inhibitors/chemistry ; PC12 Cells ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Revisiting monoamine oxidase inhibitors for the treatment of depressive disorders: A systematic review and network meta-analysis.
Autorzy :
Suchting R; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054. Electronic address: .
Tirumalajaru V; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Gareeb R; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Bockmann T; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
de Dios C; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Aickareth J; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Pinjari O; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Soares JC; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054.
Cowen PJ; Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK.
Selvaraj S; Faillace Department of Psychiatry and Behavioral Sciences, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054; Faillace Department of Psychiatry and Behavioral Sciences, Depression Research Program, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Rd, Houston, TX 77054; Houston Methodist Research Institute, Institute for Academic Medicine, 6670 Bertner St., Houston, TX 77030, USA.
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Źródło :
Journal of affective disorders [J Affect Disord] 2021 Mar 01; Vol. 282, pp. 1153-1160. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Depressive Disorder*/drug therapy
Monoamine Oxidase Inhibitors*/therapeutic use
Antidepressive Agents/therapeutic use ; Humans ; Network Meta-Analysis ; Randomized Controlled Trials as Topic
Czasopismo naukowe

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