Temat: "MORPHINE" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Experimental Study: Interleukin-31 Augments Morphine-Induced Antinociceptive Activity and Suppress Tolerance Development in Mice.
Autorzy:: Arai I; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Tsuji M; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.
Saito S; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Takeda H; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 20; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics*/pharmacology
Analgesics*/therapeutic use
Drug Tolerance*
Morphine*/pharmacology
Morphine*/therapeutic use
Animals ; Mice ; Analgesics, Opioid/pharmacology ; Dose-Response Relationship, Drug ; Interleukins/genetics ; Pruritus/drug therapy

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Skocz do pozycji: 2.

Tytuł:: Analgesic Peptides: From Natural Diversity to Rational Design.
Autorzy:: Gach-Janczak K; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
Biernat M; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Kuczer M; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Adamska-Bartłomiejczyk A; Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
Kluczyk A; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 29; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Analgesics*/pharmacology
Analgesics*/therapeutic use
Peptides*/pharmacology
Animals ; Humans ; Morphine ; Pain ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use

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Skocz do pozycji: 3.

Tytuł:: Analyzing the Antinociceptive Effect of Interleukin-31 in Mice.
Autorzy:: Arai I; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Tsuji M; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.
Takahashi K; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.
Saito S; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Takeda H; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 17; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:: Journal Article
MeSH Terms:: Capsaicin*/pharmacology
Capsaicin*/therapeutic use
Analgesics*/pharmacology
Analgesics*/therapeutic use
Mice ; Animals ; Morphine/pharmacology ; Morphine/therapeutic use ; Pain/drug therapy ; Pain/metabolism ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Interleukins/therapeutic use

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Skocz do pozycji: 4.

Tytuł:: Exploring pharmacological inhibition of G q/11 as an analgesic strategy.
Autorzy:: Marwari S; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Kowalski C; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Martemyanov KA; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (23), pp. 5196-5208. Date of Electronic Publication: 2022 Aug 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Analgesics*/pharmacology
Analgesics*/therapeutic use
Analgesics, Opioid*/pharmacology
Analgesics, Opioid*/therapeutic use
GTP-Binding Protein alpha Subunits, Gq-G11*/antagonists & inhibitors
Animals ; Mice ; Morphine/pharmacology ; Morphine/therapeutic use ; Pain/drug therapy ; Receptors, Opioid

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Skocz do pozycji: 5.

Tytuł:: The combined analgesic effect of pregabalin and morphine in the treatment of pancreatic cancer pain, a retrospective study.
Autorzy:: Dai J; Department of Pain Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Teng L; Department of Pain Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Zhao L; Department of Pain Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Zou H; Department of Pain Medicine, Harbin Medical University Cancer Hospital, Harbin, China.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2021 Mar; Vol. 10 (5), pp. 1738-1744. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics/*pharmacology
Breakthrough Pain/*drug therapy
Cancer Pain/*drug therapy
Morphine/*pharmacology
Pancreatic Neoplasms/*complications
Pregabalin/*pharmacology
Aged ; Analgesics/administration & dosage ; Analgesics/adverse effects ; Breakthrough Pain/etiology ; Cancer Pain/etiology ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Morphine/administration & dosage ; Morphine/adverse effects ; Neuralgia/drug therapy ; Pain Measurement ; Pregabalin/administration & dosage ; Pregabalin/adverse effects ; Retrospective Studies

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Skocz do pozycji: 6.

Tytuł:: Mechanisms, Characteristics, and Treatment of Neuropathic Pain and Peripheral Neuropathy Associated with Dinutuximab in Neuroblastoma Patients.
Autorzy:: Mastrangelo S; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Rivetti S; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Triarico S; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Romano A; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Attinà G; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Maurizi P; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.
Ruggiero A; Pediatric Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 23; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Analgesics/*therapeutic use
Antibodies, Monoclonal/*adverse effects
Neuralgia/*drug therapy
Neuroblastoma/*drug therapy
Peripheral Nervous System Diseases/*drug therapy
Antibodies, Monoclonal/therapeutic use ; Gabapentin/therapeutic use ; Gangliosides/metabolism ; Humans ; Morphine/therapeutic use ; Neoplasm Metastasis ; Neuralgia/chemically induced ; Neuralgia/metabolism ; Neuroblastoma/metabolism ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/metabolism

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Skocz do pozycji: 7.

Tytuł:: Morphine immunomodulation prolongs inflammatory and postoperative pain while the novel analgesic ZH853 accelerates recovery and protects against latent sensitization.
Autorzy:: Feehan AK; Brain Institute, Tulane University School of Medicine, New Orleans, LA, 70112, USA.
Zadina JE; SE LA Veterans Health Care System, New Orleans, LA, 70119, USA. .; Dept. of Medicine, Neuroscience Lab #8516, 1430 Tulane Avenue, New Orleans, LA, 70112, USA. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2019 May 21; Vol. 16 (1), pp. 100. Date of Electronic Publication: 2019 May 21.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics/*therapeutic use
Analgesics, Opioid/*therapeutic use
Immunomodulation/*drug effects
Morphine/*therapeutic use
Pain, Postoperative/*drug therapy
Peptides, Cyclic/*therapeutic use
Analgesics/pharmacology ; Analgesics, Opioid/pharmacology ; Animals ; Immunomodulation/physiology ; Inflammation/drug therapy ; Inflammation/immunology ; Male ; Morphine/pharmacology ; Pain Measurement/drug effects ; Pain Measurement/methods ; Pain, Postoperative/immunology ; Peptides, Cyclic/pharmacology ; Rats ; Rats, Sprague-Dawley ; Recovery of Function/drug effects ; Recovery of Function/physiology

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Skocz do pozycji: 8.

Tytuł:: Exercise Reduces Morphine-Induced Hyperalgesia and Antinociceptive Tolerance.
Autorzy:: Gong X; Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China.; Department of Anesthesiology and Pediatric Clinical Pharmacology Laboratory, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fan R; Department of Respiratory, Shiyan Renmin Hospital (Affiliated Hospital of Hubei University of Medicine), Shiyan, Hubei, China.
Zhu Q; Department of Laboratory, Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine), Shiyan, Hubei, China.
Ye X; Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China.
Chen Y; Department of Laboratory, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China.
Zhang M; Department of Anesthesiology and Pediatric Clinical Pharmacology Laboratory, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Sep 27; Vol. 2021, pp. 6667474. Date of Electronic Publication: 2021 Sep 27 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Physical Conditioning, Animal*
Analgesics/*pharmacology
Hyperalgesia/*chemically induced
Hyperalgesia/*pathology
Morphine/*adverse effects
Animals ; Imidazoles/pharmacology ; Male ; Phosphorylation/drug effects ; Pyridines/pharmacology ; Rats, Wistar ; Spinal Cord Dorsal Horn/drug effects ; Spinal Cord Dorsal Horn/pathology ; p38 Mitogen-Activated Protein Kinases/metabolism ; Rats

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Skocz do pozycji: 9.

Tytuł:: The impact of multimodal analgesia based enhanced recovery protocol on quality of recovery after laparoscopic gynecological surgery: a randomized controlled trial.
Autorzy:: Geng Z; Department of Anesthesiology, Peking University First Hospital, Beijing, China. .
Bi H; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Zhang D; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Xiao C; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Song H; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Feng Y; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Cao X; Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Li X; Department of Biostatics, Peking University First Hospital, Beijing, China.; Pokaż więcej
Źródło:: BMC anesthesiology [BMC Anesthesiol] 2021 Jun 28; Vol. 21 (1), pp. 179. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji:: Journal Article; Randomized Controlled Trial
MeSH Terms:: Analgesics/*administration & dosage
Gynecologic Surgical Procedures/*methods
Laparoscopy/*methods
Pain, Postoperative/*prevention & control
Adult ; Aged ; Analgesia, Patient-Controlled/methods ; Analgesics, Opioid/administration & dosage ; Female ; Humans ; Middle Aged ; Morphine/administration & dosage ; Pain Measurement ; Patient Satisfaction ; Prospective Studies ; Recovery of Function ; Time Factors

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Skocz do pozycji: 10.

Tytuł:: Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels.
Autorzy:: Tat QL; Department of Anesthesiology, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.
Joksimovic SM; Department of Anesthesiology, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.
Krishnan K; Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
Covey DF; Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.; Taylor Family Institute for Innovative Psychiatric Research, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
Todorovic SM; Department of Anesthesiology, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.; Neuroscience Graduate Program, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.
Jevtovic-Todorovic V; Department of Anesthesiology, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Dec 12; Vol. 9 (12). Date of Electronic Publication: 2020 Dec 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics/*administration & dosage
Analgesics/*therapeutic use
Calcium Channels, T-Type/*metabolism
Neurosteroids/*therapeutic use
Pain, Postoperative/*drug therapy
Pain, Postoperative/*metabolism
Analgesics/chemistry ; Analgesics/pharmacology ; Animals ; Disease Models, Animal ; Female ; Hyperalgesia/complications ; Hyperalgesia/drug therapy ; Injections, Spinal ; Morphine/administration & dosage ; Morphine/therapeutic use ; Neurosteroids/administration & dosage ; Neurosteroids/pharmacology ; Pregnanediones/chemistry ; Pregnanediones/pharmacology ; Pregnanediones/therapeutic use ; Rats, Sprague-Dawley

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Skocz do pozycji: 11.

Tytuł:: Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial.
Autorzy:: de Leeuw TG; Department of Anesthesia and Pain Medicine, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. .
Mangiarini L; Consorzio per Valutazione Biologiche e Farmacologiche, Pavia, Italy.
Lundin R; Fondazione Penta Onlus, Padova, Italy.
Kaguelidou F; Department of Pediatric Pharmacology and Pharmacogenetics, AP-HP, Hôpital Robert Debré, F-75019, Paris, France.; Inserm, CIC 1426, F-75019, Paris, France.; Université Paris Diderot, Sorbonne Paris Cité, EA 08, F-75010, Paris, France.
van der Zanden T; Intensive Care and Department of Paediatric Surgery, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Pasqua OD; University College London, London, UK.
Tibboel D; Intensive Care and Department of Paediatric Surgery, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Ceci A; Consorzio per Valutazione Biologiche e Farmacologiche, Pavia, Italy.
de Wildt SN; Intensive Care and Department of Paediatric Surgery, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Pharmacology and Toxicology, Radboud University, Nijmegen, The Netherlands.; Pokaż więcej
Corporate Authors:: GAPP consortium
Źródło:: Trials [Trials] 2019 Jan 15; Vol. 20 (1), pp. 49. Date of Electronic Publication: 2019 Jan 15.
Typ publikacji:: Clinical Trial Protocol; Journal Article
MeSH Terms:: Analgesics/*administration & dosage
Analgesics/*pharmacokinetics
Analgesics, Opioid/*administration & dosage
Chronic Pain/*drug therapy
Gabapentin/*administration & dosage
Gabapentin/*pharmacokinetics
Morphine/*administration & dosage
Neuralgia/*drug therapy
Pain Management/*methods
Administration, Oral ; Adolescent ; Age Factors ; Analgesics/adverse effects ; Analgesics, Opioid/adverse effects ; Child ; Child, Preschool ; Chronic Pain/diagnosis ; Chronic Pain/physiopathology ; Clinical Trials, Phase II as Topic ; Double-Blind Method ; Drug Therapy, Combination ; Equivalence Trials as Topic ; Female ; Gabapentin/adverse effects ; Humans ; Infant ; Male ; Morphine/adverse effects ; Multicenter Studies as Topic ; Netherlands ; Neuralgia/diagnosis ; Neuralgia/physiopathology ; Pain Management/adverse effects ; Pain Measurement ; Pharmaceutical Solutions ; Severity of Illness Index ; Treatment Outcome

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Skocz do pozycji: 12.

Tytuł:: Exchange factor directly activated by cAMP-PKCε signalling mediates chronic morphine-induced expression of purine P2X3 receptor in rat dorsal root ganglia.
Autorzy:: Wang W; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ma X; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Anesthesiology, Nantong Third People's Hospital, Nantong University, Nantong, China.
Luo L; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Huang M; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Dong J; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Zhang X; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Jiang W; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Xu T; Department of Anesthesiology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Anesthesiology, Tongzhou People's Hospital, Nantong, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2018 May; Vol. 175 (10), pp. 1760-1769. Date of Electronic Publication: 2018 Apr 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics/*pharmacology
Cyclic AMP/*metabolism
Ganglia, Spinal/*drug effects
Guanine Nucleotide Exchange Factors/*metabolism
Morphine/*pharmacology
Protein Kinase C-epsilon/*metabolism
Receptors, Purinergic P2X3/*genetics
Analgesics/administration & dosage ; Animals ; Ganglia, Spinal/metabolism ; Male ; Morphine/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Receptors, Purinergic P2X3/metabolism ; Signal Transduction

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Skocz do pozycji: 13.

Tytuł:: The effects of radio-frequency radiation (RFR) exposure on the analgesic efficacy of morphine in healthy rats and rats with inflammation.
Autorzy:: Bodera P; Military Institute of Hygiene and Epidemiology, Warsaw, Poland (Department of Microwave Safety). .
Antkowiak B; Military Institute of Hygiene and Epidemiology, Warsaw, Poland (Department of Pharmacology and Toxicology). .
Paluch M; Eppendorf Poland Ltd., Warsaw, Poland. .
Sirav B; Gazi University, Beşevler, Ankara, Turkey (Faculty of Medicine, Department of Biophysics). .
Siwicki AK; University of Warmia and Mazury, Olsztyn, Poland (Department of Microbiology and Clinical Immunology).
Stankiewicz W; Military Institute of Hygiene and Epidemiology, Warsaw, Poland (Department of Microwave Safety). .; Pokaż więcej
Źródło:: International journal of occupational medicine and environmental health [Int J Occup Med Environ Health] 2019 Jul 15; Vol. 32 (4), pp. 465-474. Date of Electronic Publication: 2019 Jul 03.
Typ publikacji:: Journal Article
MeSH Terms:: Radio Waves*
Analgesics/*pharmacology
Analgesics/*radiation effects
Morphine/*pharmacology
Morphine/*radiation effects
Animals ; Freund's Adjuvant/administration & dosage ; Inflammation/chemically induced ; Male ; Nociception/drug effects ; Nociception/radiation effects ; Pain ; Rats, Wistar

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Skocz do pozycji: 14.

Tytuł:: The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
Autorzy:: Pawlik K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Piotrowska A; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Kwiatkowski K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Ciapała K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Popiolek-Barczyk K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Makuch W; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.
Mika J; Department of Pain Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland.; Pokaż więcej
Źródło:: Immunology [Immunology] 2020 Apr; Vol. 159 (4), pp. 413-428. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics/*pharmacology
Buprenorphine/*pharmacology
Hyperalgesia/*drug therapy
Morphine/*pharmacology
Neuralgia/*drug therapy
Receptors, CCR1/*immunology
Xanthenes/*pharmacology
Animals ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/immunology ; Chemokine CCL2/genetics ; Chemokine CCL2/immunology ; Disease Models, Animal ; Drug Synergism ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/immunology ; Ganglia, Spinal/physiopathology ; Gene Expression Regulation ; Hyperalgesia/genetics ; Hyperalgesia/immunology ; Hyperalgesia/physiopathology ; Interleukin-18/genetics ; Interleukin-18/immunology ; Interleukin-1beta/genetics ; Interleukin-1beta/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology ; Male ; Microfilament Proteins/genetics ; Microfilament Proteins/immunology ; Neuralgia/genetics ; Neuralgia/immunology ; Neuralgia/physiopathology ; Nociception/drug effects ; Peroxidase/genetics ; Peroxidase/immunology ; Protein Isoforms/genetics ; Protein Isoforms/immunology ; Rats ; Rats, Wistar ; Receptors, CCR1/antagonists & inhibitors ; Receptors, CCR1/genetics ; Sciatic Nerve/drug effects ; Sciatic Nerve/injuries ; Sciatic Nerve/physiopathology ; Signal Transduction

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Skocz do pozycji: 15.

Tytuł:: Preliminary evidence of different and clinically meaningful opioid withdrawal phenotypes.
Autorzy:: Dunn KE; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Weerts EM; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Huhn AS; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Schroeder JR; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Tompkins DA; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Bigelow GE; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Strain EC; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA.; Pokaż więcej
Źródło:: Addiction biology [Addict Biol] 2020 Jan; Vol. 25 (1), pp. e12680. Date of Electronic Publication: 2018 Oct 08.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:: Analgesics/*therapeutic use
Narcotic Antagonists/*therapeutic use
Narcotics/*therapeutic use
Opiate Substitution Treatment/*methods
Opioid-Related Disorders/*drug therapy
Substance Withdrawal Syndrome/*physiopathology
Adult ; Buprenorphine/therapeutic use ; Clonidine/therapeutic use ; Cluster Analysis ; Double-Blind Method ; Female ; Humans ; Male ; Morphine/therapeutic use ; Naloxone/therapeutic use ; Phenotype ; Severity of Illness Index ; Tramadol/therapeutic use ; Treatment Outcome

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Skocz do pozycji: 16.

Tytuł:: APOLLO-2: A Randomized, Placebo and Active-Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein-Biased Ligand at the μ-Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty.
Autorzy:: Singla NK; Lotus Clinical Research, Pasadena, California, U.S.A.
Skobieranda F; Trevena Inc., Chesterbrook, Pennsylvania, U.S.A.
Soergel DG; Trevena Inc., Chesterbrook, Pennsylvania, U.S.A.
Salamea M; Trevena Inc., Chesterbrook, Pennsylvania, U.S.A.
Burt DA; Trevena Inc., Chesterbrook, Pennsylvania, U.S.A.
Demitrack MA; Trevena Inc., Chesterbrook, Pennsylvania, U.S.A.
Viscusi ER; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.; Pokaż więcej
Źródło:: Pain practice : the official journal of World Institute of Pain [Pain Pract] 2019 Sep; Vol. 19 (7), pp. 715-731. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji:: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptors, Opioid, mu*
Analgesics/*therapeutic use
Pain, Postoperative/*drug therapy
Spiro Compounds/*pharmacology
Thiophenes/*pharmacology
Abdominoplasty ; Acute Pain/drug therapy ; Adult ; Analgesia, Patient-Controlled ; Analgesics, Opioid/therapeutic use ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Morphine/administration & dosage ; Pain Management ; Pain Measurement

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Skocz do pozycji: 17.

Tytuł:: The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats.
Autorzy:: Hiranita T; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Leon F; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA.
Felix JS; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Restrepo LF; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Reeves ME; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Pennington AE; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Obeng S; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Avery BA; Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA.
McCurdy CR; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA.
McMahon LR; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA.
Wilkerson JL; Department of Pharmacodynamics, College of Pharmacy, University of Florida, P.O. Box 100487, Gainesville, FL, USA. .; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2019 Sep; Vol. 236 (9), pp. 2725-2734. Date of Electronic Publication: 2019 May 17.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics/*pharmacology
Discrimination Learning/*drug effects
Morphine/*pharmacology
Pain Measurement/*drug effects
Secologanin Tryptamine Alkaloids/*pharmacology
Analgesics, Opioid/pharmacology ; Animals ; Discrimination Learning/physiology ; Dose-Response Relationship, Drug ; Female ; Male ; Mitragyna ; Narcotic Antagonists/pharmacology ; Pain Measurement/methods ; Rats ; Rats, Sprague-Dawley ; Receptors, Opioid, mu/agonists

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Skocz do pozycji: 18.

Tytuł:: Effect of opioid-free anaesthesia on post-operative period in cardiac surgery: a retrospective matched case-control study.
Autorzy:: Guinot PG; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France. .
Spitz A; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Berthoud V; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Ellouze O; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Missaoui A; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Constandache T; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Grosjean S; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Radhouani M; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Anciaux JB; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Parthiot JP; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Merle JP; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Nowobilski N; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Nguyen M; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.
Bouhemad B; Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, 21000, Dijon, France.; Pokaż więcej
Źródło:: BMC anesthesiology [BMC Anesthesiol] 2019 Jul 31; Vol. 19 (1), pp. 136. Date of Electronic Publication: 2019 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: Cardiac Surgical Procedures*
Analgesics/*therapeutic use
Anesthetics, Local/*therapeutic use
Aged ; Airway Extubation ; Analgesics, Opioid/therapeutic use ; Antiemetics/therapeutic use ; Antihypertensive Agents/therapeutic use ; Cardiopulmonary Bypass ; Case-Control Studies ; Dexamethasone/therapeutic use ; Drug Utilization/statistics & numerical data ; Female ; Humans ; Ketamine/therapeutic use ; Length of Stay/statistics & numerical data ; Lidocaine/therapeutic use ; Male ; Middle Aged ; Morphine/therapeutic use ; Noninvasive Ventilation/statistics & numerical data ; Pain, Postoperative/prevention & control ; Retrospective Studies ; Sufentanil/therapeutic use ; Time Factors

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Skocz do pozycji: 19.

Tytuł:: The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis.
Autorzy:: Mao Y; Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang Chinese Medical University, 318 Chaowang Road, Hangzhou, Zhejiang, 310005, People's Republic of China.
Wu L; Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang Chinese Medical University, 318 Chaowang Road, Hangzhou, Zhejiang, 310005, People's Republic of China.
Ding W; Department of Orthopaedics, Tongde Hospital of Zhejiang Province, 234 Gucui Road, Hangzhou, Zhejiang, 310012, People's Republic of China. .; Pokaż więcej
Źródło:: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2016 Aug 30; Vol. 17 (1), pp. 373. Date of Electronic Publication: 2016 Aug 30.
Typ publikacji:: Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:: Amines/*therapeutic use
Analgesics/*therapeutic use
Arthroplasty, Replacement, Hip/*adverse effects
Cyclohexanecarboxylic Acids/*therapeutic use
Morphine/*therapeutic use
Pain Management/*methods
Pain, Postoperative/*drug therapy
Pregabalin/*therapeutic use
gamma-Aminobutyric Acid/*therapeutic use
Amines/administration & dosage ; Amines/adverse effects ; Analgesics/administration & dosage ; Cyclohexanecarboxylic Acids/administration & dosage ; Cyclohexanecarboxylic Acids/adverse effects ; Dizziness/chemically induced ; Dizziness/epidemiology ; Gabapentin ; Humans ; Incidence ; Morphine/administration & dosage ; Morphine/adverse effects ; Nausea/chemically induced ; Nausea/epidemiology ; Pain Measurement ; Pregabalin/administration & dosage ; Pregabalin/adverse effects ; Pruritus/chemically induced ; Pruritus/epidemiology ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Vomiting/chemically induced ; Vomiting/epidemiology ; gamma-Aminobutyric Acid/administration & dosage ; gamma-Aminobutyric Acid/adverse effects

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Skocz do pozycji: 20.

Tytuł:: Sustained exposure to acute migraine medications combined with repeated noxious stimulation dysregulates descending pain modulatory circuits: Relevance to medication overuse headache.
Autorzy:: Nation KM; 1 Department of Pharmacology, University of Arizona, Tucson, AZ, USA.
Dodick DW; 2 Mayo Clinic, Scottsdale, AZ, USA.
Navratilova E; 1 Department of Pharmacology, University of Arizona, Tucson, AZ, USA.; 2 Mayo Clinic, Scottsdale, AZ, USA.
Porreca F; 1 Department of Pharmacology, University of Arizona, Tucson, AZ, USA.; 2 Mayo Clinic, Scottsdale, AZ, USA.; Pokaż więcej
Źródło:: Cephalalgia : an international journal of headache [Cephalalgia] 2019 Apr; Vol. 39 (5), pp. 617-625. Date of Electronic Publication: 2018 Oct 04.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics/*pharmacology
Headache Disorders, Secondary/*physiopathology
Hyperalgesia/*physiopathology
Migraine Disorders/*physiopathology
Analgesics, Opioid/pharmacology ; Animals ; Male ; Morphine/pharmacology ; Rats ; Rats, Sprague-Dawley ; Repetition Priming/drug effects ; Repetition Priming/physiology ; Serotonin 5-HT1 Receptor Agonists/pharmacology ; Sumatriptan/pharmacology

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