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Tytuł:
Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry.
Autorzy:
Bhuria V; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany. .; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany. .; Center for Health and Medical Prevention - CHaMP, Otto-von-Guericke University, Magdeburg, Germany. .
Franz T; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Baldauf C; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Böttcher M; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany.; Department of Hematology and Oncology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Chatain N; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Center of Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Koschmieder S; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Center of Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Center of Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Mougiakakos D; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany.; Department of Hematology and Oncology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Schraven B; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany.; Center for Health and Medical Prevention - CHaMP, Otto-von-Guericke University, Magdeburg, Germany.
Kahlfuß S; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany.; Center for Health and Medical Prevention - CHaMP, Otto-von-Guericke University, Magdeburg, Germany.; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Fischer T; Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany. .; Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Center, Otto-von-Guericke University, Magdeburg, Germany. .; Center for Health and Medical Prevention - CHaMP, Otto-von-Guericke University, Magdeburg, Germany. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 21; Vol. 22 (1), pp. 186. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*
Myeloproliferative Disorders*/genetics
Myeloproliferative Disorders*/metabolism
Humans ; Fura-2 ; Signal Transduction ; Mutation ; Receptors, Erythropoietin/genetics ; Janus Kinase 2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cancer patients with clonal hematopoiesis die from primary malignancy or comorbidities despite higher rates of transformation to myeloid neoplasms.
Autorzy:
Chien KS; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ong F; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kim K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Li Z; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kanagal-Shamanna R; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
DiNardo CD; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Montalban-Bravo G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Hammond D; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Sasaki K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Pierce SA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kantarjian HM; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Garcia-Manero G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło:
Cancer medicine [Cancer Med] 2024 Mar; Vol. 13 (5), pp. e7093.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/epidemiology
Neoplasms*/genetics
Myeloproliferative Disorders*/epidemiology
Myeloproliferative Disorders*/genetics
Humans ; Clonal Hematopoiesis ; Retrospective Studies ; Hematopoiesis/genetics ; Comorbidity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Special Issue "Advances in Molecular Pathogenesis and Targeted Therapies for Myeloid Neoplasms".
Autorzy:
Kok CH; Precision Cancer Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide 5000, Australia.; Clinical and Health Sciences, University of South Australia, Adelaide 5000, Australia.
Yeung DT; Precision Cancer Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.; Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide 5000, Australia.
Hiwase DK; Precision Cancer Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.; Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide 5000, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Editorial
MeSH Terms:
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Myelodysplastic Syndromes*/genetics
Myelodysplastic Syndromes*/therapy
Myelodysplastic Syndromes*/pathology
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/therapy
Hematologic Neoplasms*/genetics
Hematologic Neoplasms*/therapy
Humans ; Mutation
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative Analyses of Targeted Myeloid Cancer Next-Generation Sequencing Panel in Fresh Blood, Bone Marrow and FFPE Material.
Autorzy:
Hobeck AD; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
Wendt S; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
Krohn S; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
Knuebel G; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
Bartels S; Institute of Pathology, Department of Molecular Pathology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Schipper E; Institute of Pathology, Department of Molecular Pathology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Junghanss C; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
Murua Escobar H; Clinic for Hematology, Oncology and Palliative Care, Medical Clinic III, Department of Internal Medicine, Rostock University Medical Center, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 21; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/genetics
Neoplasms*/pathology
Myeloproliferative Disorders*
Humans ; Bone Marrow/pathology ; Formaldehyde ; High-Throughput Nucleotide Sequencing/methods ; Paraffin Embedding ; Tissue Fixation ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploring the Molecular Aspects of Myeloproliferative Neoplasms Associated with Unusual Site Vein Thrombosis: Review of the Literature and Latest Insights.
Autorzy:
Morsia E; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, 60126 Ancona, Italy.
Torre E; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.
Martini F; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, 60126 Ancona, Italy.; Clinic of Gastroenterology, Hepatology, and Emergency Digestive Endoscopy, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.
Morè S; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, 60126 Ancona, Italy.
Poloni A; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, 60126 Ancona, Italy.
Olivieri A; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.; Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, 60126 Ancona, Italy.
Rupoli S; Hematology Clinic, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/pathology
Venous Thrombosis*/genetics
Venous Thrombosis*/complications
Budd-Chiari Syndrome*/complications
Budd-Chiari Syndrome*/genetics
Myeloproliferative Disorders*/complications
Myeloproliferative Disorders*/diagnosis
Myeloproliferative Disorders*/genetics
Thrombosis*/pathology
Humans ; Portal Vein ; Mutation ; Janus Kinase 2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
JAK/STAT in leukemia: a clinical update.
Autorzy:
Liang D; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Wang Q; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Zhang W; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Tang H; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Song C; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Yan Z; Department of Hematology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China. .
Liang Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China. .
Wang H; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Jan 26; Vol. 23 (1), pp. 25. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Leukemia*
Humans ; Janus Kinases/genetics ; Janus Kinases/metabolism ; STAT Transcription Factors/genetics ; STAT Transcription Factors/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Breakthrough in Blastic Plasmacytoid Dendritic Cell Neoplasm Cancer Therapy Owing to Precision Targeting of CD123.
Autorzy:
Zanotta S; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.
Galati D; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.
De Filippi R; Department of Clinical Medicine and Surgery, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Pinto A; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hematologic Neoplasms*/drug therapy
Hematologic Neoplasms*/pathology
Interleukin-3 Receptor alpha Subunit*/drug effects
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/pathology
Humans ; Dendritic Cells ; Neoplasm Recurrence, Local/pathology ; Skin Neoplasms/drug therapy ; Skin Neoplasms/pathology ; Stem Cell Transplantation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effectiveness of Ropeginterferon Alfa-2B in High-Risk Patients with Philadelphia Chromosome Negative Myeloproliferative Neoplasms- Evaluation of Clinicohaematologic Response, and Safety Profile: Single Centre Experience.
Autorzy:
Popova-Labachevska M; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Cvetanoski M; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Ridova N; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Trajkova S; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Stojanovska-Jakimovska S; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Mojsovska T; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Stojanoski Z; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Pivkova-Veljanovska A; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
Panovska-Stavridis I; 1University clinic of hematology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, RN Macedonia.
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Źródło:
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) [Pril (Makedon Akad Nauk Umet Odd Med Nauki)] 2023 Dec 18; Vol. 44 (3), pp. 57-62. Date of Electronic Publication: 2023 Dec 18 (Print Publication: 2023).
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Polycythemia Vera*/drug therapy
Polycythemia Vera*/genetics
Myeloproliferative Disorders*/diagnosis
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Humans ; Male ; Female ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Philadelphia Chromosome ; Polyethylene Glycols/adverse effects ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms.
Autorzy:
Bermes M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
Rodriguez MJ; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
de Toledo MAS; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
Ernst S; Confocal Microscopy Facility, Interdisciplinary Center for Clinical Research IZKF, RWTH Aachen University, 52074 Aachen, Germany.
Müller-Newen G; Department of Biochemistry, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.
Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
Chatain N; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
Baumeister J; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, 52074 Aachen, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), 52074 Aachen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 16; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
BRCA1 Protein*/genetics
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Neoplasms*/drug therapy
Humans ; DNA ; Germ Cells ; Haploinsufficiency ; Interferon-alpha/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; Recombinational DNA Repair ; Synthetic Lethal Mutations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Myeloproliferative Neoplasms: Contemporary Review and Molecular Landscape.
Autorzy:
Mahmud M; Department of Medicine, Midwestern University Internal Medicine Residency Consortium, Cottonwood, AZ 86326, USA.
Vasireddy S; Department of Medicine, University of Arizona Health Sciences, Tucson, AZ 85701, USA.
Gowin K; Division of Hematology and Oncology, Department of Medicine, University of Arizona Cancer Center, Tucson, AZ 85701, USA.
Amaraneni A; Division of Hematology and Oncology, Department of Medicine, University of Arizona Cancer Center, Tucson, AZ 85701, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 12; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Myeloproliferative Disorders*/diagnosis
Myeloproliferative Disorders*/genetics
Myeloproliferative Disorders*/therapy
Primary Myelofibrosis*/diagnosis
Primary Myelofibrosis*/genetics
Primary Myelofibrosis*/therapy
Neoplasms*
Humans ; Chromosome Aberrations ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The aetiology and burden of myeloproliferative neoplasms in the United Kingdom: the MyelOproliferative neoplasmS: an In-depth case-control (MOSAICC) study protocol.
Autorzy:
Abutheraa N; Aberdeen Centre for Health Data Science, Institute of Applied Health Science, School of Medicine, Medical Science and Nutrition, University of Aberdeen, Aberdeen, UK.
Tarburn EL; Aberdeen Centre for Health Data Science, Institute of Applied Health Science, School of Medicine, Medical Science and Nutrition, University of Aberdeen, Aberdeen, UK.
McShane CM; School of Medicine, Dentistry and Biomedical Sciences, Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, UK. .
Duncombe A; University Hospitals Southampton NHS Trust and Hon., University of Southampton Medical School, Southampton, UK.
McMullin MF; Centre for Medical Education School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.
Anderson LA; Aberdeen Centre for Health Data Science, Institute of Applied Health Science, School of Medicine, Medical Science and Nutrition, University of Aberdeen, Aberdeen, UK. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Dec 07; Vol. 23 (1), pp. 1207. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloproliferative Disorders*/etiology
Myeloproliferative Disorders*/genetics
Hematologic Neoplasms*
Humans ; Quality of Life ; Case-Control Studies ; United Kingdom/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blastic Plasmacytoid Dendritic Cell Neoplasm: A Comprehensive Review of the Disease, Central Nervous System Presentations, and Treatment Strategies.
Autorzy:
Mehra S; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Taylor J; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
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Źródło:
Cells [Cells] 2024 Jan 28; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Skin Neoplasms*/pathology
Myeloproliferative Disorders*/pathology
Humans ; Central Nervous System/pathology ; Dendritic Cells/pathology ; Recurrence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Venetoclax and Hypomethylating Agent Combination in Myeloid Malignancies: Mechanisms of Synergy and Challenges of Resistance.
Autorzy:
Mishra R; Department of Internal Medicine, Anne Arundel Medical Center, Annapolis, MD 21401, USA.
Zokaei Nikoo M; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Veeraballi S; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Singh A; Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 29; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Myeloproliferative Disorders*
Leukemia, Myeloid, Acute*/drug therapy
Humans ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Sulfonamides/pharmacology ; Sulfonamides/therapeutic use ; Down-Regulation ; Azacitidine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple Genomic Alterations, Including a Novel AFF4::IRF1 Fusion Gene, in a Treatment-Refractory Blastic Plasmacytoid Dendritic-Cell Neoplasm: A Case Report and Literature Review.
Autorzy:
Sahin Y; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Wang YL; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Molecular Diagnostics Lab, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Pei J; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Molecular Diagnostics Lab, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Mansoor N; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Styler M; Department of Bone Marrow Transplant and Cellular Therapies, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Testa JR; Clinical Cytogenomics Lab, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Nejati R; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 25; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 25.
Typ publikacji:
Review; Case Reports
MeSH Terms:
Hematologic Neoplasms*/drug therapy
Hematologic Neoplasms*/genetics
Myeloproliferative Disorders*
Male ; Humans ; Genomics ; Adaptor Proteins, Signal Transducing ; Death ; Transcriptional Elongation Factors ; Interferon Regulatory Factor-1/genetics
Recenzja
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Tytuł:
ETV6::ABL1 -Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment.
Autorzy:
Bochicchio MT; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Marconi G; Hematology Unit, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Baldazzi C; Istituto di Ematologia 'Seràgnoli', IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, BO, Italy.
Bandini L; Istituto di Ematologia 'Seràgnoli', IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, BO, Italy.
Ruggieri F; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40100 Bologna, BO, Italy.
Lucchesi A; Hematology Unit, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Agostinelli C; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40100 Bologna, BO, Italy.; Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, BO, Italy.
Sabattini E; Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, BO, Italy.
Orsatti A; Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, BO, Italy.
Ferrari A; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Capirossi G; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Servili C; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Ghelli Luserna di Rorà A; Fondazione Pisana per la Scienza ONLUS, 56017 San Giuliano Terme, PI, Italy.
Martinelli G; Scientific Directorate, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Simonetti G; Biosciences Laboratory, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
Rosti G; Hematology Unit, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, FC, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Case Reports
MeSH Terms:
Myeloproliferative Disorders*
Hypereosinophilic Syndrome*
Neoplasms*
Female ; Humans ; Middle Aged ; Imatinib Mesylate/therapeutic use ; Protein Kinase Inhibitors ; Cytogenetics ; Proto-Oncogene Proteins c-ets/genetics
Raport
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Tytuł:
Clinical characteristics and symptom burden of Thai myeloproliferative neoplasm patients.
Autorzy:
Cherdchoo N; Faculty of Medicine Chulalongkorn University, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Polprasert C; Faculty of Medicine Chulalongkorn University, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Faculty of Medicine, Center of excellence in Translational Hematology, Division of Hematology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand.
Rojnuckarin P; Faculty of Medicine Chulalongkorn University, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Faculty of Medicine, Center of excellence in Translational Hematology, Division of Hematology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand.
Kongkiatkamon S; Faculty of Medicine Chulalongkorn University, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Faculty of Medicine, Center of excellence in Translational Hematology, Division of Hematology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2280731. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloproliferative Disorders*/complications
Primary Myelofibrosis*/complications
Leukemia*
Humans ; Quality of Life ; Southeast Asian People
Czasopismo naukowe
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Tytuł:
Genomics of clonal evolution in a rare essential thrombocythemia with coexisting Type 2 CALR and MPL S204P mutations.
Autorzy:
Wang J; Department of Oncology and Hematology, Yizheng Hospital of Nanjing Drum Tower Hospital Group, Yizheng, PR China.; Department of Hematology, Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, Jiangsu, PR China.
Fu W; Department of Hematology, Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, Jiangsu, PR China.
Bao W; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
Gong W; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
Xu S; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
Ling C; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
Jin Q; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
Zhang Q; Department of Hematology, Nanjing Drum Tower Hospital Clinical College, Nanjing Medical University, Nanjing, Jiangsu, PR China.; Department of Hematology, The First People's Hospital of Chuzhou, Chuzhou Hospital affiliated to Anhui Medical University, Chuzhou, PR China.
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Źródło:
Platelets [Platelets] 2023 Dec; Vol. 34 (1), pp. 2176167.
Typ publikacji:
Case Reports; Review; Journal Article
MeSH Terms:
Myeloproliferative Disorders*
Thrombocythemia, Essential*/complications
Thrombocythemia, Essential*/diagnosis
Thrombocythemia, Essential*/genetics
Humans ; Calreticulin/genetics ; Janus Kinase 2/genetics ; Mutation ; Clonal Evolution ; Genomics ; Receptors, Thrombopoietin/genetics
Czasopismo naukowe
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Tytuł:
Splanchnic Vein Thrombosis in Myelofibrosis-An Underappreciated Hallmark of Disease Phenotype.
Autorzy:
Beleva EA; Clinic of Hematology, Military Medical Academy, 1606 Sofia, Bulgaria.; QSAR and Molecular Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 29; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Primary Myelofibrosis*/complications
Primary Myelofibrosis*/genetics
Myeloproliferative Disorders*/genetics
Venous Thrombosis*/genetics
Polycythemia Vera*
Thrombosis*/genetics
Thrombosis*/complications
Thrombocythemia, Essential*
Humans ; Phenotype
Czasopismo naukowe
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Tytuł:
JAK2, CALR, and MPL Mutation Profiles in Colombian patients with BCR-ABL Negative Myeloproliferative Neoplasms.
Autorzy:
Giraldo-Rincón AI; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Naranjo Molina S; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Gomez-Lopera N; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Aguirre Acevedo D; Universidad de Antioquia, Grupo Académico de Epidemiología Clinica, Medellin, Colombia.
Ucroz Benavidez A; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Gálvez Cárdenas K; Hospital Pablo Tobón Uribe, Medellín, Colombia.
Cuellar Ambrosí F; Hospital Alma Mater, Medellín, Colombia.
Torres JD; Hospital Universitario San Vicente Fundación, Medellín, Colombia.
Ospina S; Hospital Universitario San Vicente Fundación, Medellín, Colombia.
Palacio K; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Gaviria Jaramillo L; Hospital Universitario San Vicente Fundación, Medellín, Colombia.
Muñeton CM; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
Vasquez Palacio G; Universidad de Antioquia, Facultad de Medicina, Unidad de Genética Médica, Medellín, Colombia.
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Źródło:
Colombia medica (Cali, Colombia) [Colomb Med (Cali)] 2023 Sep 30; Vol. 54 (3), pp. e2035353. Date of Electronic Publication: 2023 Sep 30 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Janus Kinase 2*/genetics
Myeloproliferative Disorders*/genetics
Myeloproliferative Disorders*/metabolism
Receptors, Thrombopoietin*/genetics
Calreticulin*/genetics
Humans ; Colombia ; Mutation ; Polycythemia Vera/genetics ; Primary Myelofibrosis/genetics ; Thrombocythemia, Essential/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinical Impact of JAK2V617F Allele Burden in Philadelphia-Negative Myeloproliferative Neoplasms
Autorzy:
Yönal-Hindilerden İ; İstanbul University İstanbul Medical Faculty, Department of Internal Medicine, Division of Hematology, İstanbul, Türkiye
Şahin E; İstanbul University İstanbul Medical Faculty, Department of Internal Medicine, Division of Hematology, İstanbul, Türkiye
Hindilerden F; University of Health Sciences Türkiye Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Hematology, İstanbul, Türkiye
Dağlar-Aday A; İstanbul University İstanbul Medical Faculty, Department of Internal Medicine, Division of Medical Genetics, İstanbul, Türkiye
Nalçacı M; İstanbul University İstanbul Medical Faculty, Department of Internal Medicine, Division of Hematology, İstanbul, Türkiye
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Źródło:
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2023 Aug 31; Vol. 40 (3), pp. 174-182. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Primary Myelofibrosis*/genetics
Myeloproliferative Disorders*/diagnosis
Myeloproliferative Disorders*/genetics
Polycythemia Vera*/genetics
Thrombocythemia, Essential*/diagnosis
Thrombocythemia, Essential*/genetics
Humans ; Alleles ; Splenomegaly ; Janus Kinase 2/genetics ; Mutation
Czasopismo naukowe
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Wyświetlanie 1-20 z 3449

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