- Tytuł:
- Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
- Autorzy:
- Źródło:
- Chemical biology & drug design [Chem Biol Drug Des] 2013 Jul; Vol. 82 (1), pp. 12-21.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Antineoplastic Agents /*chemistry
Podophyllotoxin/*chemistry
Tubulin/*chemistry
Tubulin Modulators/*chemistryAntineoplastic Agents /toxicity ; Binding Sites ; Catalytic Domain ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drugs, Chinese Herbal ; HeLa Cells ; Hep G2 Cells ; Human Umbilical Vein Endothelial Cells ; Humans ; Molecular Docking Simulation ; Podophyllotoxin/analogs & derivatives ; Podophyllotoxin/toxicity ; Thermodynamics ; Tubulin/metabolism ; Tubulin Modulators/toxicity
Czasopismo naukowe