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    Wyświetlanie 1-6 z 6
    Tytuł:
    Tropism for tuft cells determines immune promotion of norovirus pathogenesis.
    Autorzy:
    Wilen CB; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Lee S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Hsieh LL; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Orchard RC; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Desai C; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Hykes BL Jr; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    McAllaster MR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Balce DR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Feehley T; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Brestoff JR; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Hickey CA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Yokoyama CC; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Wang YT; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    MacDuff DA; Department of Microbiology and Immunology, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
    Kreamalmayer D; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Howitt MR; Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
    Neil JA; Kimmel Center for Biology and Medicine at the Skirball Institute and Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
    Cadwell K; Kimmel Center for Biology and Medicine at the Skirball Institute and Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA.
    Allen PM; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Handley SA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    van Lookeren Campagne M; Department of Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
    Baldridge MT; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Virgin HW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. .
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    Źródło:
    Science (New York, N.Y.) [Science] 2018 Apr 13; Vol. 360 (6385), pp. 204-208.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Caliciviridae Infections/*immunology
    Enterocytes/*immunology
    Enterocytes/*virology
    Microbiota/*immunology
    Norovirus/*physiology
    Viral Tropism/*immunology
    Animals ; Cell Proliferation ; Cytokines/metabolism ; Mice ; Receptors, Immunologic/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity.
    Autorzy:
    Schoggins JW
    MacDuff DA
    Imanaka N
    Gainey MD
    Shrestha B
    Eitson JL
    Mar KB
    Richardson RB
    Ratushny AV
    Litvak V
    Dabelic R
    Manicassamy B
    Aitchison JD
    Aderem A
    Elliott RM
    García-Sastre A
    Racaniello V
    Snijder EJ
    Yokoyama WM
    Diamond MS
    Virgin HW
    Rice CM
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    Źródło:
    Nature [Nature] 2015 Sep 03; Vol. 525 (7567), pp. 144. Date of Electronic Publication: 2015 Jul 08.
    Typ publikacji:
    Published Erratum
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mitochondrial DNA stress primes the antiviral innate immune response.
    Autorzy:
    West AP; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Khoury-Hanold W; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Staron M; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Tal MC; Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Pineda CM; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Lang SM; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Bestwick M; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Duguay BA; Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.
    Raimundo N; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    MacDuff DA; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Kaech SM; 1] Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815-6789, USA.
    Smiley JR; Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.
    Means RE; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
    Iwasaki A; 1] Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815-6789, USA.
    Shadel GS; 1] Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Genetics, Yale School of Medicine, New Haven, Connecticut 06520, USA.
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    Źródło:
    Nature [Nature] 2015 Apr 23; Vol. 520 (7548), pp. 553-7. Date of Electronic Publication: 2015 Feb 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Stress, Physiological*
    DNA, Mitochondrial/*metabolism
    Herpesvirus 1, Human/*immunology
    Immunity, Innate/*immunology
    Animals ; Cell Line ; DNA-Binding Proteins/deficiency ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Female ; Gene Expression Regulation/genetics ; Gene Expression Regulation/immunology ; High Mobility Group Proteins/deficiency ; High Mobility Group Proteins/genetics ; High Mobility Group Proteins/metabolism ; Humans ; Interferon Regulatory Factor-3/metabolism ; Interferon Type I/immunology ; Membrane Proteins/metabolism ; Mice ; Nucleotidyltransferases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity.
    Autorzy:
    Schoggins JW; 1] Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York 10065, USA [2] Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA (J.W.S.); MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland G61 1QH, UK (R.M.E.).
    MacDuff DA; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Imanaka N; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York 10065, USA.
    Gainey MD; Rheumatology Division, Department of Medicine, and Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Shrestha B; Infectious Diseases Division, Department of Medicine and Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Eitson JL; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Mar KB; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Richardson RB; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
    Ratushny AV; 1] Seattle Biomedical Research Institute, Seattle, Washington 98109, USA [2] Institute for Systems Biology, Seattle, Washington 98109, USA.
    Litvak V; Seattle Biomedical Research Institute, Seattle, Washington 98109, USA.
    Dabelic R; Department of Microbiology and Immunology, Columbia University, New York, New York 10032, USA.
    Manicassamy B; Department of Microbiology, University of Chicago, Chicago, Illinois 60637, USA.
    Aitchison JD; 1] Seattle Biomedical Research Institute, Seattle, Washington 98109, USA [2] Institute for Systems Biology, Seattle, Washington 98109, USA.
    Aderem A; Seattle Biomedical Research Institute, Seattle, Washington 98109, USA.
    Elliott RM; 1] School of Biology, University of St Andrews, St Andrews, Scotland KY16 9ST, UK [2] Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA (J.W.S.); MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland G61 1QH, UK (R.M.E.).
    García-Sastre A; 1] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [3] Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
    Racaniello V; Department of Microbiology and Immunology, Columbia University, New York, New York 10032, USA.
    Snijder EJ; Department of Medical Microbiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.
    Yokoyama WM; Rheumatology Division, Department of Medicine, and Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Diamond MS; 1] Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA [2] Infectious Diseases Division, Department of Medicine and Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Virgin HW; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
    Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York 10065, USA.
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    Źródło:
    Nature [Nature] 2014 Jan 30; Vol. 505 (7485), pp. 691-5. Date of Electronic Publication: 2013 Nov 27.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Immunity, Innate/*genetics
    Immunity, Innate/*immunology
    Interferons/*immunology
    Nucleotidyltransferases/*immunology
    Nucleotidyltransferases/*metabolism
    Viruses/*immunology
    Animals ; Cluster Analysis ; DNA Viruses/immunology ; DNA Viruses/pathogenicity ; Flow Cytometry ; Gene Library ; Interferon Regulatory Factor-3/immunology ; Interferon Regulatory Factor-3/metabolism ; Interferons/metabolism ; Membrane Proteins/metabolism ; Mice ; Mice, Knockout ; Nucleotidyltransferases/deficiency ; Nucleotidyltransferases/genetics ; RNA Viruses/immunology ; RNA Viruses/pathogenicity ; STAT1 Transcription Factor/metabolism ; Substrate Specificity ; Viruses/classification ; Viruses/pathogenicity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    APOBEC3 inhibits DEAD-END function to regulate microRNA activity.
    Autorzy:
    Ali S; Department of Genetics, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.
    Karki N
    Bhattacharya C
    Zhu R
    MacDuff DA
    Stenglein MD
    Schumacher AJ
    Demorest ZL
    Harris RS
    Matin A
    Aggarwal S
    Pokaż więcej
    Źródło:
    BMC molecular biology [BMC Mol Biol] 2013 Jul 26; Vol. 14, pp. 16. Date of Electronic Publication: 2013 Jul 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Down-Regulation*
    Cytidine Deaminase/*metabolism
    MicroRNAs/*metabolism
    Neoplasm Proteins/*metabolism
    3' Untranslated Regions ; APOBEC-3G Deaminase ; Animals ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Cytidine Deaminase/genetics ; Gene Expression Regulation ; Humans ; Mice ; Mice, Knockout ; MicroRNAs/genetics ; Neoplasm Proteins/genetics ; Protein Binding
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.
    Autorzy:
    Demorest ZL; Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Beckman Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.
    MacDuff DA
    Brown WL
    Morham SG
    Parise LV
    Harris RS
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    Źródło:
    PloS one [PLoS One] 2010 Jul 20; Vol. 5 (7), pp. e11660. Date of Electronic Publication: 2010 Jul 20.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Calcium-Binding Proteins/*metabolism
    Cytidine Deaminase/*metabolism
    Gene Conversion/*genetics
    Immunoglobulins/*genetics
    Animals ; Blotting, Southern ; Calcium-Binding Proteins/genetics ; Cell Line ; Cytidine Deaminase/genetics ; Humans ; Immunoglobulin Class Switching ; Immunoprecipitation ; Mice ; Mice, Knockout ; Polymerase Chain Reaction ; Protein Binding
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-6 z 6

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