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Wyszukujesz frazę ""MacGowan GA"" wg kryterium: Autor


Tytuł:
Application of non-invasive bioreactance to assess hemodynamic function in patients with hypertrophic cardiomyopathy.
Autorzy:
Okwose NC; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Research Centre for Health and Life Sciences, Institute for Health and Wellbeing, Faculty of Health and Life Sciences, Coventry University, Coventry, UK.
Fuller AS; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
Alyahya AI; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
Charman SJ; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
Eggett C; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
Luke P; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
MacGowan GA; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle University, Newcastle upon Tyne, UK.
Jakovljevic DG; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Research Centre for Health and Life Sciences, Institute for Health and Wellbeing, Faculty of Health and Life Sciences, Coventry University, Coventry, UK.
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Źródło:
Physiological reports [Physiol Rep] 2023 Jun; Vol. 11 (12), pp. e15729.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiomyopathy, Hypertrophic*/diagnosis
Humans ; Female ; Adult ; Middle Aged ; Aged ; Male ; Hemodynamics/physiology ; Heart ; Cardiac Output ; Stroke Volume/physiology ; Exercise Test ; Oxygen Consumption/physiology
Czasopismo naukowe
Tytuł:
Relationship between thrombosis and infections in ventricular assist device patients.
Autorzy:
Bouzas-Cruz N; Department of Cardiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.; University of Santiago de Compostela, Santiago de Compostela, Spain.
MacGowan GA; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.; Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Biosciences and Translational and Clinical Research Institutes, Newcastle upon Tyne, UK.
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Źródło:
Artificial organs [Artif Organs] 2023 Mar; Vol. 47 (3), pp. 462-463. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Heart-Assist Devices*
Heart Failure*
Thrombosis*
Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Does infection predispose to thrombosis during long-term ventricular assist device support?
Autorzy:
Bouzas-Cruz N; Department of Cardiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.; University of Santiago de Compostela, Santiago de Compostela, Spain.
Castrodeza J; Department of Cardiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Gonzalez-Fernandez O; Department of Cardiology, Hospital Universitario La Paz, Madrid, Spain.
Ferrera C; Department of Cardiology, Hospital Clínico San Carlos, Madrid, Spain.
Woods A; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Tovey S; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Robinson-Smith N; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
McDiarmid AK; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Parry G; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Samuel J; Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK.
Schueler S; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
MacGowan GA; Department of Cardiology and Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University, Biosciences Institute, Newcastle upon Tyne, UK.
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Źródło:
Artificial organs [Artif Organs] 2022 Jul; Vol. 46 (7), pp. 1399-1408. Date of Electronic Publication: 2022 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/etiology
Heart Failure*/complications
Heart Failure*/surgery
Heart-Assist Devices*/adverse effects
Stroke*/complications
Stroke*/etiology
Thrombosis*/etiology
Humans ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Gender differences in the assessment, decision-making and outcomes for ventricular assist devices and heart transplantation: An analysis from a UK transplant center.
Autorzy:
MacGowan GA; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
McDiarmid A; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Jansen K; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Coats L; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Crossland D; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Woods A; Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
Kunadian V; Department of Cardiology, Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.; Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Shah A; Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
Schueler S; Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
Parry G; Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
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Źródło:
Clinical transplantation [Clin Transplant] 2022 Jun; Vol. 36 (6), pp. e14666. Date of Electronic Publication: 2022 Apr 18.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Failure*/surgery
Heart Transplantation*/adverse effects
Heart-Assist Devices*/adverse effects
Adult ; Female ; Humans ; Male ; Retrospective Studies ; Sex Factors ; Treatment Outcome ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł:
Comparison of cardiac output estimates by echocardiography and bioreactance at rest and peak dobutamine stress test in heart failure patients with preserved ejection fraction.
Autorzy:
Sengupta SP; Cardiology, Sengupta Hospital and Research Institute, Ravinagar Nagpur, Maharashtra, India.; Faculty of Medical Sciences, Cardiovascular Research Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Mungulmare K; Cardiology, Sengupta Hospital and Research Institute, Ravinagar Nagpur, Maharashtra, India.
Okwose NC; Faculty of Medical Sciences, Cardiovascular Research Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
MacGowan GA; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Faculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Jakovljevic DG; Faculty of Medical Sciences, Cardiovascular Research Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Faculty of Health and Life Sciences, Coventry University, Coventry, UK.
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Źródło:
Echocardiography (Mount Kisco, N.Y.) [Echocardiography] 2020 Oct; Vol. 37 (10), pp. 1603-1609. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Dobutamine*
Heart Failure*/diagnostic imaging
Cardiac Output ; Echocardiography ; Exercise Test ; Female ; Humans ; Stroke Volume ; Ventricular Function, Left
Czasopismo naukowe
Tytuł:
Association between heart rate variability and haemodynamic response to exercise in chronic heart failure.
Autorzy:
Koshy A; a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.
Okwose NC; a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.
Nunan D; b Department of Primary Care Health Sciences , University of Oxford , Oxford , UK.
Toms A; a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.
Brodie DA; c Cardiovascular Research Centre , Buckinghamshire New University , London , UK.
Doherty P; d Department of Health Sciences , University of York , York , UK.
Seferovic P; e Faculty of Medicine, University of Belgrade, and Cardiology Department , Clinical Centre Serbia , Belgrade , Serbia.
Ristic A; e Faculty of Medicine, University of Belgrade, and Cardiology Department , Clinical Centre Serbia , Belgrade , Serbia.
Velicki L; f Faculty of Medicine, University of Novi Sad, and Department of Cardiovascular Surgery , Institute of Cardiovascular Diseases Vojvodina , Novi Sad , Serbia.
Filipovic N; g Research and Development Center for Bioengineering, BioIRC, Kragujevac, Serbia; Faculty of Engineering , University of Kragujevac , Kragujevac , Serbia.
Popovic D; e Faculty of Medicine, University of Belgrade, and Cardiology Department , Clinical Centre Serbia , Belgrade , Serbia.
Skinner J; h Newcastle upon Tyne Hospitals NHS Foundation Trust , Royal Victoria Infirmary , Newcastle upon Tyne , UK.
Bailey K; h Newcastle upon Tyne Hospitals NHS Foundation Trust , Royal Victoria Infirmary , Newcastle upon Tyne , UK.
MacGowan GA; a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.
Jakovljevic DG; a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.
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Źródło:
Scandinavian cardiovascular journal : SCJ [Scand Cardiovasc J] 2019 Apr; Vol. 53 (2), pp. 77-82. Date of Electronic Publication: 2019 Apr 08.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Cardiac Output*
Exercise Tolerance*
Heart Rate*
Autonomic Nervous System/*physiopathology
Heart/*innervation
Heart Failure/*physiopathology
Adult ; Aged ; Arterial Pressure ; Chronic Disease ; Female ; Heart Failure/diagnosis ; Humans ; Male ; Middle Aged ; Models, Cardiovascular ; Prospective Studies ; Stroke Volume ; Time Factors ; Ventricular Function, Left
Czasopismo naukowe
Tytuł:
Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.
Autorzy:
Blain AM; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
Greally E; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
McClorey G; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Manzano R; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Betts CA; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Godfrey C; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
O'Donovan L; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
Coursindel T; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
Gait MJ; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
Wood MJ; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
MacGowan GA; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
Straub VW; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
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Źródło:
PloS one [PLoS One] 2018 Jun 18; Vol. 13 (6), pp. e0198897. Date of Electronic Publication: 2018 Jun 18 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell-Penetrating Peptides/*therapeutic use
Heart Failure/*etiology
Morpholinos/*therapeutic use
Muscular Dystrophy, Duchenne/*complications
Animals ; Disease Models, Animal ; Dystrophin/metabolism ; Exons/genetics ; Frameshift Mutation/genetics ; Heart/physiopathology ; Heart Failure/physiopathology ; Heart Failure/prevention & control ; Mice ; Mice, Inbred mdx ; Muscular Dystrophy, Duchenne/genetics ; Muscular Dystrophy, Duchenne/physiopathology ; Myocardium/metabolism
Czasopismo naukowe
Tytuł:
Left ventricular functional, structural and energetic effects of normal aging: Comparison with hypertension.
Autorzy:
Parikh JD; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom.
Hollingsworth KG; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom.
Wallace D; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom.
Blamire AM; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom.
MacGowan GA; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom.; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Cardiology Freeman Hospital, Newcastle upon Tyne, United Kingdom.
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Źródło:
PloS one [PLoS One] 2017 May 11; Vol. 12 (5), pp. e0177404. Date of Electronic Publication: 2017 May 11 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Aging/*physiology
Hypertension/*physiopathology
Ventricular Function, Left/*physiology
Aged ; Blood Pressure/physiology ; Cross-Sectional Studies ; Diastole/physiology ; Echocardiography ; Female ; Heart Ventricles/physiopathology ; Humans ; Linear Models ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Pulse Wave Analysis ; Systole/physiology
Czasopismo naukowe
Tytuł:
Pregnancy in cardiac transplant recipients.
Autorzy:
Bhagra CJ; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK. .
Bhagra SK; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.
Donado A; Departments of Cardiothoracic Surgery and Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Butt T; Departments of Cardiothoracic Surgery and Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Forrest L; Departments of Cardiothoracic Surgery and Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
MacGowan GA; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.
Parry G; Departments of Cardiothoracic Surgery and Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
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Źródło:
Clinical transplantation [Clin Transplant] 2016 Sep; Vol. 30 (9), pp. 1059-65. Date of Electronic Publication: 2016 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Transplantation*
Registries*
Pregnancy Complications, Cardiovascular/*epidemiology
Adolescent ; Adult ; Female ; Follow-Up Studies ; Graft Survival ; Heart Diseases/surgery ; Humans ; Incidence ; Infant, Newborn ; Pregnancy ; Pregnancy Outcome ; Retrospective Studies ; Surveys and Questionnaires ; Survival Rate/trends ; Time Factors ; United Kingdom/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł:
Cardiac structure and function are altered in type 2 diabetes and non-alcoholic fatty liver disease and associate with glycemic control.
Autorzy:
Cassidy S
Hallsworth K
Thoma C
MacGowan GA
Hollingsworth KG
Day CP
Taylor R
Jakovljevic DG
Trenell MI
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2015 Feb 13; Vol. 14, pp. 23. Date of Electronic Publication: 2015 Feb 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Glucose/*metabolism
Diabetes Mellitus, Type 2/*blood
Glycemic Index/*physiology
Non-alcoholic Fatty Liver Disease/*blood
Ventricular Remodeling/*physiology
Adult ; Aged ; Case-Control Studies ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Humans ; Magnetic Resonance Imaging, Cine/methods ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/diagnosis ; Risk Factors
Czasopismo naukowe
Tytuł:
Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.
Autorzy:
Hollingsworth KG; Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK. />Willis TA
Bates MG
Dixon BJ
Lochmüller H
Bushby K
Bourke J
MacGowan GA
Straub V
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Źródło:
European journal of heart failure [Eur J Heart Fail] 2013 Sep; Vol. 15 (9), pp. 986-94. Date of Electronic Publication: 2013 Apr 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heart/*physiopathology
Muscular Dystrophies, Limb-Girdle/*complications
Pericardium/*physiopathology
Ventricular Dysfunction, Left/*etiology
Adult ; Aged ; Female ; Humans ; Magnetic Resonance Imaging, Cine ; Male ; Middle Aged ; Muscular Dystrophies, Limb-Girdle/genetics ; Mutation ; Pentosyltransferases ; Prospective Studies ; Proteins/genetics ; Spectrum Analysis ; Stroke Volume ; Systole ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Dysfunction, Left/physiopathology ; Young Adult
Czasopismo naukowe
Tytuł:
Heterogeneous abnormalities of in-vivo left ventricular calcium influx and function in mouse models of muscular dystrophy cardiomyopathy.
Autorzy:
Greally E; Institute of Genetic Medicine, Newcastle University, International Center for Life, Newcastle, UK.
Davison BJ
Blain A
Laval S
Blamire A
Straub V
MacGowan GA
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Źródło:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance [J Cardiovasc Magn Reson] 2013 Jan 16; Vol. 15, pp. 4. Date of Electronic Publication: 2013 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium Signaling*/drug effects
Ventricular Function, Left*/drug effects
Cardiomyopathies/*metabolism
Muscular Dystrophy, Duchenne/*metabolism
Myocardium/*metabolism
Age Factors ; Animals ; Calcium Channel Blockers/pharmacology ; Calcium Channels, L-Type/drug effects ; Calcium Channels, L-Type/metabolism ; Cardiomyopathies/genetics ; Cardiomyopathies/pathology ; Cardiomyopathies/physiopathology ; Chlorides ; Contrast Media ; Disease Models, Animal ; Disease Progression ; Genotype ; Heart Rate ; Hypertrophy, Left Ventricular/metabolism ; Hypertrophy, Left Ventricular/pathology ; Hypertrophy, Left Ventricular/physiopathology ; Magnetic Resonance Imaging ; Male ; Manganese Compounds ; Mice ; Mice, Inbred mdx ; Mice, Knockout ; Muscular Dystrophy, Duchenne/genetics ; Muscular Dystrophy, Duchenne/pathology ; Muscular Dystrophy, Duchenne/physiopathology ; Myocardium/pathology ; Phenotype ; Sarcoglycans/deficiency ; Sarcoglycans/genetics ; Stroke Volume ; Time Factors
Czasopismo naukowe
Tytuł:
Beta-blockers, left and right ventricular function, and in-vivo calcium influx in muscular dystrophy cardiomyopathy.
Autorzy:
Blain A; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, United Kingdom.
Greally E
Laval S
Blamire A
Straub V
MacGowan GA
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (2), pp. e57260. Date of Electronic Publication: 2013 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenergic beta-Antagonists/*pharmacology
Calcium/*metabolism
Cardiomyopathies/*drug therapy
Metoprolol/*pharmacology
Muscular Dystrophies/*drug therapy
Ventricular Function, Left/*drug effects
Ventricular Function, Right/*drug effects
Animals ; Body Weight/drug effects ; Calcium/agonists ; Cardiomyopathies/metabolism ; Cardiomyopathies/pathology ; Ion Transport/drug effects ; Male ; Mice ; Mice, Inbred mdx ; Mice, Knockout ; Muscular Dystrophies/metabolism ; Muscular Dystrophies/pathology ; Organ Size/drug effects ; Sarcoglycans/deficiency ; Sarcoglycans/genetics ; Stroke Volume/drug effects
Czasopismo naukowe
Tytuł:
Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy.
Autorzy:
Bauer R (AUTHOR)
Blain A (AUTHOR)
Greally E (AUTHOR)
Bushby K (AUTHOR)
Lochmüller H (AUTHOR)
Laval S (AUTHOR)
Straub V (AUTHOR)
Macgowan GA (AUTHOR)
Bauer, Ralf (AUTHOR)
Blain, Alison (AUTHOR)
Greally, Elizabeth (AUTHOR)
Bushby, Kate (AUTHOR)
Lochmüller, Hanns (AUTHOR)
Laval, Steve (AUTHOR)
Straub, Volker (AUTHOR)
MacGowan, Guy A (AUTHOR)
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Źródło:
European Journal of Heart Failure. Nov2010, Vol. 12 Issue 11, p1163-1170. 8p.
Czasopismo naukowe
Tytuł:
Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy.
Autorzy:
Bauer R; Institute of Human Genetics, Newcastle University, International Center for Life, Newcastle upon Tyne, UK.
Straub V
Blain A
Bushby K
MacGowan GA
Pokaż więcej
Źródło:
European journal of heart failure [Eur J Heart Fail] 2009 May; Vol. 11 (5), pp. 463-71. Date of Electronic Publication: 2009 Feb 20.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Angiotensin-Converting Enzyme Inhibitors/*administration & dosage
Cardiomyopathies/*drug therapy
Dystrophin/*deficiency
Glucocorticoids/*administration & dosage
Myocardium/*metabolism
Ventricular Dysfunction, Left/*chemically induced
Administration, Oral ; Animals ; Captopril/administration & dosage ; Cardiomyopathies/complications ; Cardiomyopathies/metabolism ; Diastole ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Gene Expression Regulation ; Glucocorticoids/adverse effects ; Male ; Mice ; Mice, Inbred C57BL ; Myocardial Contraction/drug effects ; Myocardium/pathology ; Prednisolone/administration & dosage ; Prednisolone/adverse effects ; RNA/drug effects ; RNA/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Sarcolemma/drug effects ; Sarcolemma/pathology ; Treatment Outcome ; Tumor Necrosis Factor-alpha/drug effects ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Ventricular Dysfunction, Left/drug therapy ; Ventricular Dysfunction, Left/physiopathology
Czasopismo naukowe
Tytuł:
Interaction of implantable defibrillator therapy with angiotensin-converting enzyme deletion/insertion polymorphism.
Autorzy:
Bedi MS; Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2582, USA.
Postava LA
Murali S
Macgowan GA
Mathier M
McNamara DM
London B
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Źródło:
Journal of cardiovascular electrophysiology [J Cardiovasc Electrophysiol] 2004 Oct; Vol. 15 (10), pp. 1162-6.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Defibrillators, Implantable*
Arrhythmias, Cardiac/*mortality
Arrhythmias, Cardiac/*therapy
Peptidyl-Dipeptidase A/*genetics
Alleles ; Death, Sudden, Cardiac ; Female ; Gene Deletion ; Genotype ; Humans ; Male ; Middle Aged ; Polymorphism, Genetic ; Survival Rate ; Telemetry
Czasopismo naukowe

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