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Wyszukujesz frazę ""Macrophage Activation"" wg kryterium: Temat


Tytuł :
Comparison of baseline laboratory findings of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis and multisystem inflammatory syndrome in children.
Autorzy :
Aydın F; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Çelikel E; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Ekici Tekin Z; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Coşkun S; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Sezer M; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Karagöl C; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Kaplan MM; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Tekgöz N; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Kurt T; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Özcan S; Division of Pediatric Intensive Care Unit, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Kavurt AV; Division of Pediatric Cardiology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Özkaya Parlakay A; Division of Pediatric Infectious Disease, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Çelikel Acar B; Division of Pediatric Rheumatology, Department of Pediatrics, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
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Źródło :
International journal of rheumatic diseases [Int J Rheum Dis] 2021 Apr; Vol. 24 (4), pp. 542-547. Date of Electronic Publication: 2021 Feb 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Macrophage Activation*
C-Reactive Protein/*metabolism
COVID-19/*diagnosis
Ferritins/*blood
Fibrinogen/*metabolism
Macrophage Activation Syndrome/*diagnosis
Systemic Inflammatory Response Syndrome/*diagnosis
Biomarkers/blood ; COVID-19/blood ; COVID-19/complications ; Child ; Female ; Follow-Up Studies ; Humans ; Leukocyte Count ; Macrophage Activation Syndrome/blood ; Macrophage Activation Syndrome/etiology ; Male ; Retrospective Studies ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/blood ; Systemic Inflammatory Response Syndrome/complications
SCR Disease Name :
pediatric multisystem inflammatory disease, COVID-19 related
Czasopismo naukowe
Tytuł :
Unexpected macrophage activation syndrome in a healthy young woman: a case report.
Autorzy :
Saviano A; Department of Emergency Medicine, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy. .
Petrucci M
Tilli P
Pignataro G
Petruzziello C
Giuliano G
Ojetti V
Covino M
Franceschi F
Candelli M
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Źródło :
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2020 Jul; Vol. 24 (13), pp. 7320-7323.
Typ publikacji :
Case Reports
MeSH Terms :
Macrophage Activation*
Macrophage Activation Syndrome/*diagnosis
Macrophages/*immunology
Adult ; Disease Progression ; Fatal Outcome ; Female ; Humans ; Macrophage Activation Syndrome/complications ; Macrophage Activation Syndrome/immunology ; Macrophage Activation Syndrome/therapy ; Multiple Organ Failure/etiology ; Treatment Failure
Raport
Tytuł :
Pathogenesis and Treatment of Refractory Disease Courses in Systemic Juvenile Idiopathic Arthritis: Refractory Arthritis, Recurrent Macrophage Activation Syndrome and Chronic Lung Disease.
Autorzy :
Erkens R; Division of Pediatric Rheumatology & Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands; Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, the Netherlands.
Esteban Y; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Towe C; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Schulert G; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Vastert S; Division of Pediatric Rheumatology & Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands; Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, the Netherlands. Electronic address: .
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Źródło :
Rheumatic diseases clinics of North America [Rheum Dis Clin North Am] 2021 Nov; Vol. 47 (4), pp. 585-606. Date of Electronic Publication: 2021 Aug 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Arthritis, Juvenile*/complications
Arthritis, Juvenile*/drug therapy
Lung Diseases*
Macrophage Activation Syndrome*/diagnosis
Macrophage Activation Syndrome*/etiology
Macrophage Activation Syndrome*/therapy
Biological Therapy ; Child ; Humans
Czasopismo naukowe
Tytuł :
Macrophage activation syndrome triggered by systemic lupus erythematosus flare: successful treatment with a combination of dexamethasone sodium phosphate, intravenous immunoglobulin, and cyclosporine: a case report.
Autorzy :
Gouda W; Department of Rheumatology, Faculty of Medicine, Al Azhar University, Assiut, Egypt. .; Department of Rheumatology, Al-Sabah Hospital, Kuwait, Kuwait. .
Alsaqabi F; Department of Rheumatology, Al-Sabah Hospital, Kuwait, Kuwait.
Moshrif A; Department of Rheumatology, Faculty of Medicine, Al Azhar University, Assiut, Egypt.
Abbas AS; Department of Rheumatology, Faculty of Medicine, Al Azhar University, Assiut, Egypt.
Abdel-Aziz TM; Department of Rheumatology, Faculty of Medicine, Al Azhar University, Assiut, Egypt.
Islam MA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 Oct 07; Vol. 15 (1), pp. 497. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Lupus Erythematosus, Systemic*/complications
Lupus Erythematosus, Systemic*/drug therapy
Macrophage Activation Syndrome*/drug therapy
Macrophage Activation Syndrome*/etiology
Adult ; Cyclosporine/therapeutic use ; Dexamethasone/analogs & derivatives ; Female ; Humans ; Immunoglobulins, Intravenous ; Methylprednisolone/therapeutic use
Czasopismo naukowe
Tytuł :
Evaluating the multivisceral involvement on adult-onset Still's disease to retrieve imaging-based differences in patients with and without macrophage activation syndrome: results from a single-centre observational study.
Autorzy :
Di Cola I; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Bruno F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Berardicurti O; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Monti R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Conforti A; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Di Sibio A; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Pavlych V; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Masciocchi C; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Barile A; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Cipriani P; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.
Ruscitti P; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy. .
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Źródło :
Clinical rheumatology [Clin Rheumatol] 2021 Oct; Vol. 40 (10), pp. 3971-3978. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Macrophage Activation Syndrome*/complications
Macrophage Activation Syndrome*/diagnostic imaging
Still's Disease, Adult-Onset*/complications
Still's Disease, Adult-Onset*/diagnostic imaging
Adult ; Ferritins ; Humans ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Hyperinflammation: On the pathogenesis and treatment of macrophage activation syndrome.
Autorzy :
Andersson U; Department of Women's and Children's Health, Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden.
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Źródło :
Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2021 Oct; Vol. 110 (10), pp. 2717-2722. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Lymphohistiocytosis, Hemophagocytic*/etiology
Lymphohistiocytosis, Hemophagocytic*/therapy
Macrophage Activation Syndrome*/etiology
Macrophage Activation Syndrome*/therapy
Cytokines ; Humans ; Killer Cells, Natural
Czasopismo naukowe
Tytuł :
Efficacy of Moderately Dosed Etoposide in Macrophage Activation Syndrome-Hemophagocytic Lymphohistiocytosis.
Autorzy :
Horne A; A.C. Horne, MD, PhD, M. Meeths, MD, PhD, Childhood Cancer Research Unit, and Pediatric Rheumatology Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's Health, Karolinska University Hospital, Stockholm; .
von Bahr Greenwood T; T. von Bahr Greenwood, MD, J.I. Henter, Professor, MD, PhD, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's Health, Karolinska University Hospital, Stockholm.
Chiang SCC; S.C. Chiang, PhD, Y.T. Bryceson, PhD, Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, and Karolinska University Hospital Huddinge, Stockholm.
Meeths M; A.C. Horne, MD, PhD, M. Meeths, MD, PhD, Childhood Cancer Research Unit, and Pediatric Rheumatology Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's Health, Karolinska University Hospital, Stockholm.
Björklund C; C. Björklund, MD, Department of Pediatric Hematology and Oncology, Umeå University Hospital, Umeå.
Ekelund M; M. Ekelund, MD, Department of Pediatrics, Ryhov County Hospital, Jönköping, and Department of Women's and Children's Health, Uppsala University, Uppsala.
Erensjö P; P. Erensjö, MD, Department of Pediatrics, Falun Hospital, Falun.
Berg S; S. Berg, MD, PhD, Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg.
Hagelberg S; S. Hagelberg, MD, PhD, U. Andersson, Professor, MD, PhD, Pediatric Rheumatology Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, and Theme of Children's Health, Karolinska University Hospital, Stockholm, Sweden.
Bryceson YT; S.C. Chiang, PhD, Y.T. Bryceson, PhD, Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, and Karolinska University Hospital Huddinge, Stockholm.
Andersson U; S. Hagelberg, MD, PhD, U. Andersson, Professor, MD, PhD, Pediatric Rheumatology Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, and Theme of Children's Health, Karolinska University Hospital, Stockholm, Sweden.
Henter JI; T. von Bahr Greenwood, MD, J.I. Henter, Professor, MD, PhD, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's Health, Karolinska University Hospital, Stockholm.
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Źródło :
The Journal of rheumatology [J Rheumatol] 2021 Oct; Vol. 48 (10), pp. 1596-1602. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis, Juvenile*/complications
Arthritis, Juvenile*/drug therapy
Lymphohistiocytosis, Hemophagocytic*/drug therapy
Macrophage Activation Syndrome*/drug therapy
Sepsis*
Etoposide/therapeutic use ; Humans
Czasopismo naukowe
Tytuł :
Discrimination of COVID-19 From Inflammation-Induced Cytokine Storm Syndromes Using Disease-Related Blood Biomarkers.
Autorzy :
Kessel C; Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.
Vollenberg R; Department of Gastroenterology, Hepatology, Endocrinology and Clinical Infectiology, University Hospital Muenster, Muenster, Germany.
Masjosthusmann K; Department of General Pediatrics, University Children's Hospital Muenster, Muenster, Germany.
Hinze C; Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.
Wittkowski H; Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.
Debaugnies F; Laboratory of Translational Research, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium and Medical Biology Department, Laboratoire National de Santé, Dudelange, Luxembourg.
Nagant C; Immunology Department, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium.
Corazza F; Laboratory of Translational Research, Centre Hospitalier Universitaire Brugmann and Immunology Department, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium.
Vély F; Aix Marseille Université, CNRS, INSERM, CIML and Assistance Publique des Hôpitaux de Marseille, Hôpital de la Timone, Immunology, Marseille Immunopole, Marseilles, France.
Kaplanski G; Assistance Publique-Hôpitaux de Marseille, Centre Hospitalier Universitaire Conception, Service de Médecine Interne et Immunologie Clinique, Aix-Marseille Universitô and Center for Cardiovascular Research and Nutrition, Aix-Marseille Université, INSERM UMRS1263, Marseilles, France.
Girard-Guyonvarc'h C; Division of Rheumatology, Department of Medicine, University Hospital of GenevaDepartment of Medicine, University Hospital of Geneva, University of Geneva, Geneva, Switzerland.
Gabay C; Division of Rheumatology, Department of Medicine, University Hospital of GenevaDepartment of Medicine, University Hospital of Geneva, University of Geneva, Geneva, Switzerland.
Schmidt H; Department of Gastroenterology, Hepatology, Endocrinology and Clinical Infectiology, University Hospital Muenster, Muenster, Germany.
Foell D; Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany.
Tepasse PR; Department of Gastroenterology, Hepatology, Endocrinology and Clinical Infectiology, University Hospital Muenster, Muenster, Germany.
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Źródło :
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2021 Oct; Vol. 73 (10), pp. 1791-1799. Date of Electronic Publication: 2021 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*diagnosis
Cytokine Release Syndrome/*etiology
Interleukin-18/*blood
Interleukin-8/*blood
Lymphohistiocytosis, Hemophagocytic/*diagnosis
Macrophage Activation Syndrome/*diagnosis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; COVID-19/blood ; COVID-19/complications ; Cytokine Release Syndrome/blood ; Diagnosis, Differential ; Female ; Humans ; Lymphohistiocytosis, Hemophagocytic/blood ; Lymphohistiocytosis, Hemophagocytic/complications ; Macrophage Activation Syndrome/blood ; Macrophage Activation Syndrome/complications ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Tapering Doses of Methylprednisolone Pulse in the Treatment of Macrophage Activation Syndrome Associated with Systemic Juvenile Idiopathic Arthritis.
Autorzy :
Loganathan S; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Banday A; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Jindal AK; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. .
Sudhakar M; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Patra N; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Pulipaka S; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Bansal R; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Mohanandia B; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Singh S; Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
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Źródło :
Indian journal of pediatrics [Indian J Pediatr] 2021 Oct; Vol. 88 (10), pp. 1056. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Letter
MeSH Terms :
Arthritis, Juvenile*/complications
Arthritis, Juvenile*/drug therapy
Macrophage Activation Syndrome*/drug therapy
Macrophage Activation Syndrome*/etiology
Cyclosporine ; Heart Rate ; Humans ; Methylprednisolone
Opinia redakcyjna
Tytuł :
The role of interleukin-18 in the diagnosis and monitoring of hemophagocytic lymphohistiocytosis/macrophage activation syndrome - a systematic review.
Autorzy :
Krei JM; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
Møller HJ; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Larsen JB; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2021 Feb; Vol. 203 (2), pp. 174-182. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Interleukin-18/*immunology
Lymphohistiocytosis, Hemophagocytic/*diagnosis
Macrophage Activation Syndrome/*diagnosis
Macrophages/*immunology
Monitoring, Immunologic/*methods
Animals ; Diagnosis, Differential ; Humans ; Lymphohistiocytosis, Hemophagocytic/immunology ; Macrophage Activation ; Macrophage Activation Syndrome/immunology ; Phenotype
Czasopismo naukowe
Tytuł :
Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia.
Autorzy :
Brands X; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
de Vries FMC; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Uhel F; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Haak BW; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Peters-Sengers H; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Schuurman AR; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
van Engelen TSR; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Lutter R; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Respiratory Medicine and Experimental Immunology, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Cremer OL; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Bonten MJ; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Julius Center for Health Sciences and Primary Care, University of Utrecht, Utrecht, The Netherlands.
Schultz MJ; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Respiratory Medicine and Experimental Immunology, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Julius Center for Health Sciences and Primary Care, University of Utrecht, Utrecht, The Netherlands.; Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Mahidol-Oxford Tropical Medicine Research Unit (MORU), Mahidol University, Bangkok, Thailand.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Division of Infectious Diseases, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Scicluna BP; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
van der Poll T; Center for Experimental and Molecular Medicine (CEMM), Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Division of Infectious Diseases, Amsterdam University Medical Centers - Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
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Corporate Authors :
MARS Consortium
Źródło :
Critical care medicine [Crit Care Med] 2021 Nov 01; Vol. 49 (11), pp. 1901-1911.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Macrophage Activation*
Community-Acquired Infections/*blood
Critical Illness/*therapy
Ferritins/*blood
Pneumonia, Bacterial/*blood
Aged ; Biomarkers/blood ; Cohort Studies ; Community-Acquired Infections/therapy ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Netherlands ; Pneumonia, Bacterial/therapy ; Prospective Studies ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Autorzy :
Di Conza G; Department of Oncology, University of Lausanne, Epalinges, Switzerland.; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.
Tsai CH; Department of Oncology, University of Lausanne, Epalinges, Switzerland.; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.
Gallart-Ayala H; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Yu YR; Department of Oncology, University of Lausanne, Epalinges, Switzerland.; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.
Franco F; Department of Oncology, University of Lausanne, Epalinges, Switzerland.; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.
Zaffalon L; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Xie X; Program in Biology, Division of Science and Mathematics, New York University, Abu Dhabi, United Arab Emirates.
Li X; Department of Oncology, University of Lausanne, Epalinges, Switzerland.; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland.
Xiao Z; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.; Institute of Infections and Immunity, Translational Medicine Institute, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Raines LN; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Falquet M; Department of Oncology, University of Lausanne, Epalinges, Switzerland.
Jalil A; Lipids Nutrition Cancer-LNC, INSERM-Université de Bourgogne, Dijon, France.
Locasale JW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, USA.
Percipalle P; Program in Biology, Division of Science and Mathematics, New York University, Abu Dhabi, United Arab Emirates.; Department of Molecular Bioscience, Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
Masson D; Lipids Nutrition Cancer-LNC, INSERM-Université de Bourgogne, Dijon, France.
Huang SC; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Martinon F; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Ivanisevic J; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Ho PC; Department of Oncology, University of Lausanne, Epalinges, Switzerland. .; Ludwig Institute for Cancer Research, University of Lausanne, Epalinges, Switzerland. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Nov; Vol. 22 (11), pp. 1403-1415. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Macrophage Activation*
Endoplasmic Reticulum/*metabolism
Intracellular Membranes/*metabolism
Melanoma/*metabolism
Membrane Lipids/*metabolism
Skin Neoplasms/*metabolism
Tumor-Associated Macrophages/*metabolism
Animals ; Cell Line, Tumor ; Cell Survival ; Endoplasmic Reticulum/ultrastructure ; Glucosylceramidase/metabolism ; Intracellular Membranes/ultrastructure ; Melanoma/genetics ; Melanoma/ultrastructure ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Phenotype ; Phosphorylation ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Skin Neoplasms/genetics ; Skin Neoplasms/ultrastructure ; Tumor Escape ; Tumor Microenvironment ; Tumor-Associated Macrophages/ultrastructure ; X-Box Binding Protein 1/genetics ; X-Box Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
SPION-MSCs enhance therapeutic efficacy in sepsis by regulating MSC-expressed TRAF1-dependent macrophage polarization.
Autorzy :
Xu Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, 22 Hankou Road, Nanjing, 210093, China.
Liu X; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, 22 Hankou Road, Nanjing, 210093, China.
Li Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, 22 Hankou Road, Nanjing, 210093, China.
Dou H; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, 22 Hankou Road, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, 210093, China.
Liang H; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China. .
Hou Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, 22 Hankou Road, Nanjing, 210093, China. .; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, 210093, China. .
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Źródło :
Stem cell research & therapy [Stem Cell Res Ther] 2021 Oct 09; Vol. 12 (1), pp. 531. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Activation*
Sepsis*/therapy
Animals ; Macrophages ; Magnetic Iron Oxide Nanoparticles ; Mice ; TNF Receptor-Associated Factor 1
Czasopismo naukowe
Tytuł :
K regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages.
Autorzy :
Cristea I; Department of Clinical Medicine, University of Bergen, Norway.
Bruland O; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.
Rødahl E; Department of Clinical Medicine, University of Bergen, Norway.; Department of Ophthalmology, Haukeland University Hospital, Bergen, Norway.
Bredrup C; Department of Clinical Medicine, University of Bergen, Norway.; Department of Ophthalmology, Haukeland University Hospital, Bergen, Norway.
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Źródło :
FEBS letters [FEBS Lett] 2021 Oct; Vol. 595 (19), pp. 2437-2446. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Activation*
Inflammasomes/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Potassium/*metabolism
Cell Line ; Humans ; Protein Transport
Czasopismo naukowe
Tytuł :
Transfer of miRNA in tumor-derived exosomes suppresses breast tumor cell invasion and migration by inducing M1 polarization in macrophages.
Autorzy :
Moradi-Chaleshtori M; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shojaei S; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammadi-Yeganeh S; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Hashemi SM; Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119800. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Genetic Therapy*
Macrophage Activation*
Breast Neoplasms/*therapy
Exosomes/*genetics
MicroRNAs/*therapeutic use
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/immunology ; Cell Proliferation ; Female ; Mice ; Mice, Inbred C57BL ; MicroRNAs/administration & dosage ; MicroRNAs/genetics ; Phagocytosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Enterococcus faecalis sustained infection induces macrophage pro-resolution polarization.
Autorzy :
Polak D; Department of Periodontology, Jerusalem, Israel.
Yaya A; Department of Periodontology, Jerusalem, Israel.; Department of Endodontics, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.
Levy DH; Department of Endodontics, IDF Medical Corps, Sheba Hospital, Tel Aviv, Israel.
Metzger Z; Departments of Endodontology and Oral Biology, The Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.
Abramovitz I; Department of Endodontics, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.
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Źródło :
International endodontic journal [Int Endod J] 2021 Oct; Vol. 54 (10), pp. 1840-1849. Date of Electronic Publication: 2021 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Enterococcus faecalis*
Macrophage Activation*
Cell Differentiation ; Humans ; Macrophages ; Phagocytosis
Czasopismo naukowe
Tytuł :
Macrophage Activation Syndrome and COVID 19: Impact of MAPK Driven Immune-Epigenetic Programming by SARS-Cov-2.
Autorzy :
Roy RK; Amity Institute of Virology and Immunology, Amity University, NOIDA, Udham Singh Nagar, India.
Sharma U; Department of Zoology, Central University of Punjab, Bathinda, India.
Wasson MK; Amity Institute of Virology and Immunology, Amity University, NOIDA, Udham Singh Nagar, India.
Jain A; Department of Zoology, Central University of Punjab, Bathinda, India.
Hassan MI; Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, India.
Prakash H; Amity Institute of Virology and Immunology, Amity University, NOIDA, Udham Singh Nagar, India.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Oct 01; Vol. 12, pp. 763313. Date of Electronic Publication: 2021 Oct 01 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*pathology
Epigenesis, Genetic/*genetics
Macrophage Activation Syndrome/*pathology
Macrophages/*immunology
p38 Mitogen-Activated Protein Kinases/*metabolism
Humans ; Immunity, Innate/genetics ; Immunity, Innate/immunology ; Lung/pathology ; Macrophage Activation Syndrome/genetics ; Respiratory Distress Syndrome/immunology ; Respiratory Distress Syndrome/pathology ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Dickkopf-2 knockdown protects against classic macrophage polarization and lipid loading by activation of Wnt/β-catenin signaling.
Autorzy :
Zhang Y; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China.
Wu H; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China.
He R; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China.
Ye C; Department of Cardiology, Chongqing Qijiang District People's Hospital, Chongqing, PR China.
Chen H; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China.
Wang J; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China.
Li Z; Center of Cardiology, Chong Qing General Hospital, University of Chinese Academy of Sciences, Chongqing, PR China. Electronic address: .
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Źródło :
Journal of cardiology [J Cardiol] 2021 Oct; Vol. 78 (4), pp. 328-333. Date of Electronic Publication: 2021 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Activation*
Wnt Signaling Pathway*
Animals ; Lipids ; Macrophages/metabolism ; Mice ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Line-selective macrophage activation with an anti-CD40 antibody drives a hemophagocytic syndrome in mice.
Autorzy :
Ingoglia G; Division of Internal Medicine and.
Yalamanoglu A; Division of Internal Medicine and.
Pfefferlé M; Division of Internal Medicine and.
Dubach IL; Division of Internal Medicine and.
Schaer CA; Institute of Anesthesiology, University of Zurich, Zurich, Switzerland.
Valkova K; Division of Internal Medicine and.
Hansen K; Division of Internal Medicine and.
Schulthess N; Division of Internal Medicine and.
Humar R; Division of Internal Medicine and.
Schaer DJ; Division of Internal Medicine and.
Vallelian F; Division of Internal Medicine and.
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Źródło :
Blood advances [Blood Adv] 2020 Jun 23; Vol. 4 (12), pp. 2751-2761.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphohistiocytosis, Hemophagocytic*
Macrophage Activation Syndrome*
Animals ; Interferon-gamma ; Macrophage Activation ; Macrophages ; Mice
Czasopismo naukowe
Tytuł :
Predicting Macrophage Activation Syndrome in Childhood-onset Systemic Lupus Erythematosus Patients at Diagnosis.
Autorzy :
Gerstein M; M. Gerstein, MD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada, and Pediatric Rheumatology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Borgia RE; R.E. Borgia, MD, Division of Rheumatology, The Hospital for Sick Children, Toronto, and Department of Pediatrics, College of Medicine, University of Florida, Gainesville, Florida, USA.
Dominguez D; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Feldman BM; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Liao F; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Levy DM; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Ng L; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Abdelhaleem M; M. Abdelhaleem, MBBCh, PhD, FRCPC, Division of Haematopathology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Silverman ED; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada.
Hiraki LT; D. Dominguez, MD, MSc, B.M. Feldman, MD, MSc, FRCPC, F. Liao, MSc, D.M. Levy, MD, MS, FRCPC, L. Ng, BSc, E.D. Silverman, MD, FRCPC, L.T. Hiraki, MD, FRCPC, ScD, Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario Canada; .
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Źródło :
The Journal of rheumatology [J Rheumatol] 2021 Sep; Vol. 48 (9), pp. 1450-1457. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lupus Erythematosus, Systemic*/diagnosis
Macrophage Activation Syndrome*/diagnosis
Macrophage Activation Syndrome*/etiology
Rheumatology*
Child ; Fever ; Humans ; Retrospective Studies ; United States
Czasopismo naukowe

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