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Tytuł :
Fatty acid binding protein 3 deficiency limits atherosclerosis development via macrophage foam cell formation inhibition.
Autorzy :
Tan L; Department of Cardiology, The Central Hospital Affiliated to Shenyang Medical College, Shenyang, Liaoning, People's Republic of China; Department of Cardiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, People's Republic of China. Electronic address: .
Lu J; Department of Cardiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, People's Republic of China.
Liu L; Department of Cardiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, People's Republic of China.
Li L; Department of Cardiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning, People's Republic of China.
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Oct 01; Vol. 407 (1), pp. 112768. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*metabolism
Atherosclerosis/*pathology
Cholesterol/*metabolism
Fatty Acid Binding Protein 3/*deficiency
Macrophages/*metabolism
Animals ; Fatty Acid Binding Protein 3/metabolism ; Lipid Metabolism/physiology ; Macrophages/pathology ; Macrophages, Peritoneal/metabolism ; PPAR gamma/metabolism
Czasopismo naukowe
Tytuł :
Prognostic significance of CD163+ tumor-associated macrophages in colorectal cancer.
Autorzy :
Xue T; Department of Traumatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.
Yan K; Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang Province, China.
Cai Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 1 West Fanhai Road, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Sun J; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 1 West Fanhai Road, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Chen Z; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 1 West Fanhai Road, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Chen X; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 1 West Fanhai Road, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Wu W; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, No. 1 West Fanhai Road, Ouhai District, Wenzhou, 325000, Zhejiang Province, China. .
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Źródło :
World journal of surgical oncology [World J Surg Oncol] 2021 Jun 24; Vol. 19 (1), pp. 186. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*
Tumor-Associated Macrophages*
Antigens, CD ; Antigens, Differentiation, Myelomonocytic ; Humans ; Macrophages ; Prognosis ; Receptors, Cell Surface
Czasopismo naukowe
Tytuł :
Pulmonary administration of a CSF-1R inhibitor alters the balance of tumor-associated macrophages and supports first-line chemotherapy in a lung cancer model.
Autorzy :
Zhang H; Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Almuqbil RM; Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Alhudaithi SS; Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
Sunbul FS; Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States.
da Rocha SRP; Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Apr 01; Vol. 598, pp. 120350. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Lung Neoplasms*/drug therapy
Macrophages*
Receptor, Macrophage Colony-Stimulating Factor*/antagonists & inhibitors
Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Cisplatin/administration & dosage ; Cisplatin/pharmacology ; Humans ; Lung ; Mice ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/pharmacology ; Receptor Protein-Tyrosine Kinases ; Small Molecule Libraries/administration & dosage ; Small Molecule Libraries/pharmacology ; Tumor Microenvironment ; Tumor-Associated Macrophages
Czasopismo naukowe
Tytuł :
[Polarized activation affects iron metabolism in macrophages].
Autorzy :
Li YQ; Analysis Center of Agrobiology and Environmental Science, Zhejiang University, Hangzhou 310058, China.
Liang L; Key Laboratory of Animal Molecular Nutrition, Ministry of Education, Zhejiang University, Hangzhou 310058, China.; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Gan ZS; Key Laboratory of Animal Molecular Nutrition, Ministry of Education, Zhejiang University, Hangzhou 310058, China.; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Tang XY; Key Laboratory of Animal Molecular Nutrition, Ministry of Education, Zhejiang University, Hangzhou 310058, China.; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
DU HH; Key Laboratory of Animal Molecular Nutrition, Ministry of Education, Zhejiang University, Hangzhou 310058, China.; College of Animal Science, Zhejiang University, Hangzhou 310058, China. .
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Źródło :
Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2021 Apr 25; Vol. 73 (2), pp. 244-252.
Typ publikacji :
Journal Article
MeSH Terms :
Cytokines*
Macrophages*/metabolism
Animals ; Ferritins ; Iron/metabolism ; Macrophages, Alveolar/metabolism ; Swine
Czasopismo naukowe
Tytuł :
Macrophage-Based Approaches for Cancer Immunotherapy.
Autorzy :
Anderson NR; Carisma Therapeutics, Philadelphia, Pennsylvania.
Minutolo NG; Carisma Therapeutics, Philadelphia, Pennsylvania.
Gill S; Department of Hematology Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.
Klichinsky M; Carisma Therapeutics, Philadelphia, Pennsylvania. .
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Źródło :
Cancer research [Cancer Res] 2021 Mar 01; Vol. 81 (5), pp. 1201-1208. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Macrophages*/pathology
Macrophages*/transplantation
Immunotherapy/*methods
Neoplasms/*therapy
Animals ; Cell- and Tissue-Based Therapy/methods ; Humans ; Immunotherapy, Adoptive/methods ; Neoplasms/pathology ; Tumor-Associated Macrophages/drug effects ; Tumor-Associated Macrophages/pathology
Czasopismo naukowe
Tytuł :
Therapeutic targeting of tumor-associated macrophages.
Autorzy :
Rasmussen RK; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Etzerodt A; Department of Biomedicine, Aarhus University, Aarhus, Denmark. Electronic address: .
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Źródło :
Advances in pharmacology (San Diego, Calif.) [Adv Pharmacol] 2021; Vol. 91, pp. 185-211. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/drug therapy
Tumor-Associated Macrophages*
Humans ; Macrophages ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Tumor-Associated Macrophages as Potential Targets for Anti-Cancer Activity of Marine Invertebrate-Derived Compounds.
Autorzy :
Dolmatova LS; Laboratory of Biochemistry, V.I. Il`ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, Russian Federation.
Dolmatov IY; Laboratory of Comparative Cytology, National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, Russian Federation.
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Źródło :
Current pharmaceutical design [Curr Pharm Des] 2021; Vol. 27 (28), pp. 3139-3160.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasms*/drug therapy
Tumor-Associated Macrophages*
Animals ; Immunotherapy ; Invertebrates ; Macrophages ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Glycolytic Reprogramming in Silica-Induced Lung Macrophages and Silicosis Reversed by Ac-SDKP Treatment.
Autorzy :
Mao N; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Yang H; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Yin J; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Li Y; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Jin F; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Li T; Hebei Key Laboratory for Chronic Diseases, Basic Medical College, North China University of Science and Technology, Tangshan 063210, China.
Yang X; Hebei Key Laboratory for Chronic Diseases, Basic Medical College, North China University of Science and Technology, Tangshan 063210, China.
Sun Y; Hebei Key Laboratory for Chronic Diseases, Basic Medical College, North China University of Science and Technology, Tangshan 063210, China.
Liu H; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Xu H; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Yang F; Hebei Key Laboratory for Organ Fibrosis Research, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Glycolysis*
Lung/*drug effects
Macrophages/*drug effects
Silicon Dioxide/*adverse effects
Silicosis/*therapy
Animals ; Fibroblasts/metabolism ; Inflammation/drug therapy ; Macrophages, Alveolar/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Oligopeptides/pharmacology ; Pulmonary Fibrosis/metabolism ; RNA, Small Interfering/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Oral Squamous Cell Carcinoma Contributes to Differentiation of Monocyte-Derived Tumor-Associated Macrophages via PAI-1 and IL-8 Production.
Autorzy :
Kai K; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Moriyama M; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.; OBT Research Center, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Haque ASMR; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.; Department of Dental Anatomy, Udayan Dental College, House No: 1, Ward No: 7, Chondipur, GPO, Rajpara, Rajshahi 6000, Bangladesh.
Hattori T; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Chinju A; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Hu C; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Kubota K; Department of Oral-Maxillofacial Surgery, Dentistry and Orthodontics, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Miyahara Y; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Kakizoe-Ishiguro N; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Kawano S; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Nakamura S; Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 31; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
Macrophages/*metabolism
Squamous Cell Carcinoma of Head and Neck/*metabolism
Carcinoma, Squamous Cell/pathology ; Cell Differentiation/genetics ; Cell Line, Tumor ; Head and Neck Neoplasms/pathology ; Humans ; Immunohistochemistry ; Interleukin-8/metabolism ; Interleukin-8/physiology ; Leukocytes, Mononuclear/cytology ; Macrophages/physiology ; Plasminogen Activator Inhibitor 1/metabolism ; Plasminogen Activator Inhibitor 1/physiology ; Squamous Cell Carcinoma of Head and Neck/pathology ; Tumor Microenvironment ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/physiology
Czasopismo naukowe
Tytuł :
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease.
Autorzy :
Mulder K; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Patel AA; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France.
Kong WT; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Piot C; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Halitzki E; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.
Dunsmore G; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France.
Khalilnezhad S; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Irac SE; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Dubuisson A; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France.
Chevrier M; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Zhang XM; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Tam JKC; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore.
Lim TKH; Department of Pathology, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore.
Wong RMM; Genome Institute of Singapore, A(∗)STAR, 60 Biopolis Street, Genome, #02-01, Singapore 138672, Singapore.
Pai R; Genome Institute of Singapore, A(∗)STAR, 60 Biopolis Street, Genome, #02-01, Singapore 138672, Singapore.
Khalil AIS; Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.
Chow PKH; Division of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore.
Wu SZ; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Al-Eryani G; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Roden D; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Swarbrick A; The Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Chan JKY; Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore 229899, Singapore; Academic Clinical Program in Obstetrics and Gynaecology, Duke-NUS Medical School, Singapore 169857, Singapore; Experimental Fetal Medicine Group, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore; Program in Emerging Infectious Disease, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Albani S; Translational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore.
Derosa L; Gustave Roussy Cancer Campus, Villejuif, France; Cancer Medicine Department, Gustave Roussy, Villejuif, France.
Zitvogel L; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France; Cancer Medicine Department, Gustave Roussy, Villejuif, France; Université Paris-Saclay, Ile-de-France, France; Center of Clinical Investigations in Biotherapies of Cancer (BIOTHERIS), 1428 Villejuif, France.
Sharma A; Genome Institute of Singapore, A(∗)STAR, 60 Biopolis Street, Genome, #02-01, Singapore 138672, Singapore; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, the University of Western Australia, PO Box 7214, 6 Verdun Street, Nedlands, Perth, WA 6009, Australia; School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Institute, Curtin University, Perth, WA 6102, Australia.
Chen J; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore.
Silvin A; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France.
Bertoletti A; Program in Emerging Infectious Disease, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Blériot C; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France.
Dutertre CA; Gustave Roussy Cancer Campus, Villejuif, France; Institut National de la Santé Et de la Recherche Médicale (INSERM) U1015, Equipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Translational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore. Electronic address: .
Ginhoux F; Singapore Immunology Network (SIgN), A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Translational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: .
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Źródło :
Immunity [Immunity] 2021 Aug 10; Vol. 54 (8), pp. 1883-1900.e5. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells/*immunology
Gene Expression/*immunology
Monocytes/*immunology
Transcriptome/*genetics
Tumor-Associated Macrophages/*immunology
Arthritis, Rheumatoid/immunology ; COVID-19/immunology ; Gene Expression/genetics ; Gene Expression Profiling ; Humans ; Interferon-gamma/immunology ; L-Amino Acid Oxidase/metabolism ; Liver Cirrhosis/immunology ; Macrophages/immunology ; Neoplasms/immunology ; RNA, Small Cytoplasmic/genetics ; Single-Cell Analysis ; T-Lymphocytes, Regulatory/immunology ; Transcriptome/immunology
Czasopismo naukowe
Tytuł :
Mst1/2-ALK promotes NLRP3 inflammasome activation and cell apoptosis during Listeria monocytogenes infection.
Autorzy :
Gao A; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China.
Tang H; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China.
Zhang Q; Department of Histology and Embryology, School of Medicine, Nankai University, Tianjin, 300071, P. R. China.
Liu R; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China.
Wang L; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China.
Liu Y; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China.
Qi Z; Department of Histology and Embryology, School of Medicine, Nankai University, Tianjin, 300071, P. R. China. .
Shen Y; School of Medical Laboratory, Tianjin Medical University, Tianjin, 300203, P. R. China. .
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Źródło :
Journal of microbiology (Seoul, Korea) [J Microbiol] 2021 Jul; Vol. 59 (7), pp. 681-692. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Anaplastic Lymphoma Kinase/*metabolism
Inflammasomes/*immunology
Listeria monocytogenes/*immunology
Macrophages/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Animals ; Cell Line, Tumor ; Cytokines/metabolism ; Down-Regulation ; Female ; Inflammasomes/metabolism ; JNK Mitogen-Activated Protein Kinases/genetics ; JNK Mitogen-Activated Protein Kinases/metabolism ; Macrophages/metabolism ; Macrophages/microbiology ; Macrophages, Peritoneal/immunology ; Mice ; Mice, Inbred C57BL ; NIMA-Related Kinases/genetics ; NIMA-Related Kinases/metabolism ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Granulocyte Macrophage-Colony Stimulating Factor Reverses HIV Protein-Induced Mitochondrial Derangements in Alveolar Macrophages.
Autorzy :
Staitieh BS; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Auld SC; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Ahmed M; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Fan X; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Smirnova N; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Yeligar SM; Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.; Atlanta VA Health Care System, Decatur, Georgia, USA.
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Źródło :
AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2021 Mar; Vol. 37 (3), pp. 224-232. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
HIV Infections*/drug therapy
HIV Infections*/metabolism
Macrophages, Alveolar*
Animals ; Granulocyte-Macrophage Colony-Stimulating Factor ; Granulocytes ; Human Immunodeficiency Virus Proteins/metabolism ; Humans ; Macrophages ; Mitochondria ; Rats
Czasopismo naukowe
Tytuł :
Human lung macrophages: roll up for the MISTRG tour.
Autorzy :
Jardine L; Biosciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Haematology Department, Freeman Hospital, the Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK. Electronic address: .
Haniffa M; Biosciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, the Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4LP, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK. Electronic address: .
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Źródło :
Immunity [Immunity] 2021 Feb 09; Vol. 54 (2), pp. 194-196.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Lung*
Macrophages, Alveolar*
Animals ; Humans ; Macrophages ; Mice ; Monocytes
Czasopismo naukowe
Tytuł :
Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection.
Autorzy :
Zhu B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Wu Y; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Huang S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Zhang R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Son YM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Li C; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Cheon IS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Gao X; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Wang M; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Chen Y; Versiti Blood Research Institute, Milwaukee, WI 53226, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Wauwatosa, WI 53226, USA.
Zhou X; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Division of Rheumatology, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Nguyen Q; Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Phan AT; Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Behl S; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Taketo MM; Division of Experimental Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mack M; Department of Nephrology, University Hospital Regensburg, 93053 Regensburg, Germany.
Shapiro VS; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Zeng H; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Division of Rheumatology, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Ebihara H; Department of Molecular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Mullon JJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Edell ES; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Reisenauer JS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Demirel N; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Kern RM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.
Chakraborty R; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Cui W; Versiti Blood Research Institute, Milwaukee, WI 53226, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Wauwatosa, WI 53226, USA.
Kaplan MH; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zhou X; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Goldrath AW; Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Sun J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA. Electronic address: .
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Źródło :
Immunity [Immunity] 2021 Jun 08; Vol. 54 (6), pp. 1200-1218.e9. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
COVID-19/*immunology
COVID-19/*virology
Cell Self Renewal/*immunology
Host-Pathogen Interactions/*immunology
Macrophages/*immunology
SARS-CoV-2/*immunology
Biomarkers ; COVID-19/metabolism ; Cytokines/metabolism ; Disease Susceptibility/immunology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Inflammation Mediators/metabolism ; Macrophages/cytology ; Macrophages/metabolism ; Macrophages, Alveolar/immunology ; Macrophages, Alveolar/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Tumour-associated macrophages process drug and radio-conjugates of the dead tumour cell-targeting APOMAB® antibody.
Autorzy :
Staudacher AH; Translational Oncology Laboratory, Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia; School of Medicine, University of Adelaide, Adelaide, SA 5000, Australia. Electronic address: .
Liapis V; Translational Oncology Laboratory, Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia.
Tieu W; School of Medicine, University of Adelaide, Adelaide, SA 5000, Australia; Molecular Imaging and Therapy Research Unit (MITRU), South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Wittwer NL; Translational Oncology Laboratory, Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia.
Brown MP; Translational Oncology Laboratory, Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5000, Australia; School of Medicine, University of Adelaide, Adelaide, SA 5000, Australia; Cancer Clinical Trials Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2020 Nov 10; Vol. 327, pp. 779-787. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmaceutical Preparations*
Tumor-Associated Macrophages*
Antibodies, Monoclonal ; Cell Line, Tumor ; Macrophages
Czasopismo naukowe
Tytuł :
Targeted Delivery of Dasatinib to Deplete Tumor-Associated Macrophages by Mannosylated Mixed Micelles for Tumor Immunotherapy.
Autorzy :
Zhang X; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016 PR China.
Zang X; School of Basic Medicine, Qingdao University, Ningxia Road 308, Qingdao 266071, PR China.
Qiao M; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016 PR China.
Zhao X; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016 PR China.
Hu H; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016 PR China.
Chen D; School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016 PR China.
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Źródło :
ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2020 Oct 12; Vol. 6 (10), pp. 5675-5684. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Micelles*
Tumor-Associated Macrophages*
Dasatinib/therapeutic use ; Immunotherapy ; Macrophages
Czasopismo naukowe
Tytuł :
Taraxacum mongolicum extract inhibited malignant phenotype of triple-negative breast cancer cells in tumor-associated macrophages microenvironment through suppressing IL-10 / STAT3 / PD-L1 signaling pathways.
Autorzy :
Deng XX; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, PR China; Ningxia Medical University Pharmacy College, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Research Center of Modern Hui Medicine Engineering and Technology, Yinchuan, 750004, PR China.
Jiao YN; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, PR China.
Hao HF; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, PR China.
Xue D; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, PR China. Electronic address: .
Bai CC; Ningxia Medical University Pharmacy College, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Research Center of Modern Hui Medicine Engineering and Technology, Yinchuan, 750004, PR China. Electronic address: .
Han SY; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jun 28; Vol. 274, pp. 113978. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
B7-H1 Antigen/*antagonists & inhibitors
Drugs, Chinese Herbal/*pharmacology
Interleukin-10/*antagonists & inhibitors
STAT3 Transcription Factor/*antagonists & inhibitors
Taraxacum/*chemistry
Triple Negative Breast Neoplasms/*metabolism
Tumor-Associated Macrophages/*metabolism
B7-H1 Antigen/metabolism ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Drugs, Chinese Herbal/chemistry ; Humans ; Interleukin-10/metabolism ; Macrophages/drug effects ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/pathology ; Tumor Microenvironment ; Tumor-Associated Macrophages/drug effects
Czasopismo naukowe
Tytuł :
Fusobacterium nucleatum Facilitates M2 Macrophage Polarization and Colorectal Carcinoma Progression by Activating TLR4/NF- κ B/S100A9 Cascade.
Autorzy :
Hu L; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Liu Y; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Kong X; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Wu R; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Peng Q; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Zhang Y; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Zhou L; Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China.
Duan L; Department of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 21; Vol. 12, pp. 658681. Date of Electronic Publication: 2021 May 21 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calgranulin B/*metabolism
Colorectal Neoplasms/*etiology
Colorectal Neoplasms/*metabolism
Macrophage Activation/*immunology
Macrophages/*immunology
Macrophages/*metabolism
NF-kappa B/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; Cell Line, Tumor ; Cell Movement/immunology ; Cell Plasticity/immunology ; Colorectal Neoplasms/pathology ; Disease Models, Animal ; Disease Susceptibility ; Female ; Fusobacterium Infections/immunology ; Fusobacterium Infections/microbiology ; Fusobacterium nucleatum/immunology ; Heterografts ; Humans ; Mice ; Models, Biological ; Signal Transduction ; Tumor Microenvironment/immunology ; Tumor-Associated Macrophages/immunology ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/pathology
Czasopismo naukowe
Tytuł :
The Role of Macrophages in the Pathogenesis of SARS-CoV-2-Associated Acute Respiratory Distress Syndrome.
Autorzy :
Kosyreva A; Department of Neuromorphology, Science Research Institute of Human Morphology, Moscow, Russia.; Histology Department, Peoples Friendship University of Russia (RUDN University), Moscow, Russia.
Dzhalilova D; Department of Immunomorphology of Inflammation, Science Research Institute of Human Morphology, Moscow, Russia.
Lokhonina A; Histology Department, Peoples Friendship University of Russia (RUDN University), Moscow, Russia.; Department of Regenerative Medicine, National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation, Moscow, Russia.
Vishnyakova P; Histology Department, Peoples Friendship University of Russia (RUDN University), Moscow, Russia.; Department of Regenerative Medicine, National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation, Moscow, Russia.
Fatkhudinov T; Histology Department, Peoples Friendship University of Russia (RUDN University), Moscow, Russia.; Department of Growth and Development, Science Research Institute of Human Morphology, Moscow, Russia.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 10; Vol. 12, pp. 682871. Date of Electronic Publication: 2021 May 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*pathology
Macrophages/*immunology
Respiratory Distress Syndrome/*pathology
COVID-19/complications ; COVID-19/immunology ; COVID-19/therapy ; Cell- and Tissue-Based Therapy ; Humans ; Inflammation ; Lung/immunology ; Lung/pathology ; Macrophage Activation ; Macrophages/transplantation ; Macrophages, Alveolar/immunology ; Monocytes/immunology ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/immunology ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Acid Aspiration Impairs Antibacterial Properties of Liver Macrophages.
Autorzy :
Langelage M; Justus-Liebig-University Giessen Giessen, Germany.
Better J; Justus-Liebig-University Giessen Giessen, Germany.
Wetstein M; Justus-Liebig-University Giessen Giessen, Germany.
Selvakumar B; Biomedicine Research Institute of Buenos Aires - CONICET-Partner Institute of the Max Planck Society (IBioBA-MPSP) Buenos Aires, Argentina.; Max Planck Institute for Heart and Lung Research Bad Nauheim, Germany.
Malainou C; Justus-Liebig-University Giessen Giessen, Germany.
Kimmig L; Justus-Liebig-University Giessen Giessen, Germany.; University of Chicago Medicine Chicago, Illinois and.
Arneth B; Giessen University Hospital Giessen, Germany.
Köhler K; Justus-Liebig-University Giessen Giessen, Germany.
Herden C; Justus-Liebig-University Giessen Giessen, Germany.
Herold S; Justus-Liebig-University Giessen Giessen, Germany.
Matt U; Justus-Liebig-University Giessen Giessen, Germany.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 May; Vol. 64 (5), pp. 641-643.
Typ publikacji :
Letter
MeSH Terms :
Klebsiella Infections/*immunology
Liver/*immunology
Lung/*immunology
Macrophages/*immunology
Pneumonia, Aspiration/*immunology
Pneumonia, Bacterial/*immunology
Pseudomonas Infections/*immunology
Animals ; Colony Count, Microbial ; Disease Models, Animal ; Immunity, Innate ; Klebsiella Infections/microbiology ; Klebsiella Infections/pathology ; Klebsiella pneumoniae/immunology ; Klebsiella pneumoniae/pathogenicity ; Liver/microbiology ; Lung/microbiology ; Macrophages/microbiology ; Macrophages, Alveolar/immunology ; Macrophages, Alveolar/microbiology ; Macrophages, Peritoneal/immunology ; Macrophages, Peritoneal/microbiology ; Mice ; Organ Specificity ; Peritoneum/immunology ; Peritoneum/microbiology ; Phagocytosis ; Pneumonia, Aspiration/microbiology ; Pneumonia, Aspiration/pathology ; Pneumonia, Bacterial/microbiology ; Pneumonia, Bacterial/pathology ; Primary Cell Culture ; Pseudomonas Infections/microbiology ; Pseudomonas Infections/pathology ; Pseudomonas aeruginosa/immunology ; Pseudomonas aeruginosa/pathogenicity ; Reactive Oxygen Species/immunology ; Reactive Oxygen Species/metabolism ; Spleen/immunology ; Spleen/microbiology
Opinia redakcyjna

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